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SaveShare Save Share Save Share Save Share Save Share Save Invention of MK-8262, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor Backup to Anacetrapib with Best-in-Class Properties
Vachal, Petr; Duffy, Joseph L.; Campeau, Louis-Charles; Amin, Rupesh P.; Mitra, Kaushik; Murphy, Beth Ann; Shao, Pengcheng P.; Sinclair, Peter J.; Ye, Feng; Katipally, Revathi; Lu, Zhijian; Ondeyka, Debra; Chen, Yi-Heng; Zhao, Kake; Sun, Wanying; Tyagarajan, Sriram; Bao, Jianming; Wang, Sheng-Ping; Cote, Josee; Lipardi, Concetta; Metzger, Daniel; Leung, Dennis; Hartmann, Georgy; Wollenberg, Gordon K.; Liu, Jian; Tan, Lushi; Xu, Yingju; Chen, Qinghao; Liu, Guiquan; Blaustein, Robert O.; Johns, Douglas G. Share Save Share Save Share Save Share Save Share Save Discovery of Benzimidazole Oxazolidinediones as Novel and Selective Nonsteroidal Mineralocorticoid Receptor AntagonistsYang, Christine; Balsells, Jaume; Chu, Hong D.; Cox, Jason M.; Crespo, Alejandro; Ma, Xiuying; Contino, Lisa; Brown, Patricia; Gao, Sheng; Zamlynny, Beata; Wiltsie, Judyann; Clemas, Joseph; Lisnock, Jean Marie; Gibson, Jack; Zhou, Gaochao; Garcia-Calvo, Margarita; Bateman, Thomas J.; Tong, Vincent; Xu, Ling; Crook, Martin; Sinclair, Peter; Shen, Hong C. Share Save Share Save Share Save Biphenyl-Substituted Oxazolidinones as Cholesteryl Ester Transfer Protein Inhibitors: Modifications of the Oxazolidinone Ring Leading to the Discovery of AnacetrapibSmith, Cameron J.; Ali, Amjad; Hammond, Milton L.; Li, Hong; Lu, Zhijian; Napolitano, Joann; Taylor, Gayle E.; Thompson, Christopher F.; Anderson, Matt S.; Chen, Ying; Eveland, Suzanne S.; Guo, Qiu; Hyland, Sheryl A.; Milot, Denise P.; Sparrow, Carl P.; Wright, Samuel D.; Cumiskey, Anne-Marie; Latham, Melanie; Peterson, Laurence B.; Rosa, Ray; Pivnichny, James V.; Tong, Xinchun; Xu, Suoyu S.; Sinclair, Peter J. Share Save Discovery of Substituted Biphenyl Oxazolidinone Inhibitors of Cholesteryl Ester Transfer ProteinThompson, Christopher F.; Ali, Amjad; Quraishi, Nazia; Lu, Zhijian; Hammond, Milton L.; Sinclair, Peter J.; Anderson, Matt S.; Eveland, Suzanne S.; Guo, Qiu; Hyland, Sheryl A.; Milot, Denise P.; Sparrow, Carl P.; Wright, Samuel D. Share Save Share Save Biochemical characterization of cholesteryl ester transfer protein inhibitorsRanalletta, Mollie; Bierilo, Kathleen K.; Chen, Ying; Milot, Denise; Chen, Qing; Tung, Elaine; Houde, Caroline; Elowe, Nadine H.; Garcia-Calvo, Margarita; Porter, Gene; Eveland, Suzanne; Frantz-Wattley, Betsy; Kavana, Mike; Addona, George; Sinclair, Peter; Sparrow, Carl; O'Neill, Edward A.; Koblan, Ken S.; Sitlani, Ayesha; Hubbard, Brian; Fisher, Timothy S. Share Save An inhibitor of Janus kinase 2 prevents polycythemia in miceMathur, Anjili; Mo, Jan-Rung; Kraus, Manfred; O'Hare, Erin; Sinclair, Peter; Young, Jonathan; Zhao, Shuxia; Wang, Yuxun; Kopinja, Johnny; Qu, Xianlu; Reilly, John; Walker, Deborah; Xu, Lin; Aleksandrowicz, Daniel; Marshall, Gary; Scott, Martin L.; Kohl, Nancy E.; Bachman, Eric Share Save Share Save 
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