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M

Mostafa M. Hamed

helmholtz centre for infection research

13H-index
65Paper Count
777Citation Count
Published Papers 30
Publication Date
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Targeting the Energy-Coupling Factor Transporters: A Novel Antibiotic Drug Target in Streptococcus pneumoniae
errJournal of Medicinal Chemistry
IF6.8
err2026-06-12
err0
errOAAI
errEleonora Diamanti; Amelieke J.H. Cremers; Yue Li; Ioulia Exapicheidou; Carole Baumann; Paddy Gibson; Atanaz Shams; Louise Martin; Rouven Becker; Inda Setyawati; Lucie Zeimetz; Jörg Haupenthal; Matthias Witschel; Dirk J. Slotboom; Jennifer Herrmann; Katharina Rox; Mostafa M. Hamed; Jan-Willem Veening; Anna K. H. Hirsch
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Design and Optimization of Simplified Inhibitors Targeting E. coli and K. pneumoniae IspE
errrsc med. chem.
IF0
err2026-01-09
err0
errOAAI
errDanica Walsh; Rawia Hamid; Tim Giele; Matthias Rottmann; Anna J Hirsch; Mostafa Hamed; Norbert Reiling
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A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum
errAngewandte Chemie International Edition
IF16.9
err2025-10-20
err0
errOAAI
errDr. Patricia Bravo; Dr. Eleonora Diamanti; Dr. Mostafa M. Hamed; Dr. Lorenzo Bizzarri; Dr. Natalie Wiedemar; Armin Passecker; Prof. Dr. Nicolas M. B. Brancucci; Dr. Anna Albisetti; Christin Gumpp; Dr. Boris Illarionov; Dr. Markus Fischer; Dr. Matthias Witschel; Tobias Schehl; Dr. Hannes Hahne; Prof. Dr. Pascal Mäser; Dr. Matthias Rottmann; Prof. Dr. Anna K. H. Hirsch
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Design and Simulation of All-Inorganic Wide-Bandgap CsPbIBr2 Solar Cells for Indoor Photovoltaic Applications
errNanomaterials and Nanotechnology
IF3.3
err2025-10-09
err0
errOAAI
errMostafa Hamed; Mona El Sabbagh; Marwa S. Salem; Mohamed Okil; Mostafa Salah; Ahmed Shaker
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Targeting isoprenoid precursor biosynthesis in Klebsiella pneumoniae: Design, synthesis and evaluation of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) inhibitors
errBioorganic Chemistry
IF4.7
err2025-08-15
err0
errOAAI
errSidra Eisa; Antoine Lacour; Sandra Johannsen; Rawia Hamid; Prateek Raj; Dirk W. Heinz; Mostafa M. Hamed; Eleonora Diamanti; Anna K.H. Hirsch
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From Dyrk1A inhibitors to a novel class of antiviral agents: Targeting Enterovirus EV-A71 with 2-aryl-substituted thiophene scaffolds
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-04-01
err0
PREAI
errKeddis, Parthiena M.; Tu, Tuong-Khanh My; Scherer, Hugo; Kany, Andreas M.; Hafez, Donia E.; Darwish, Sarah S.; Abadi, Ashraf H.; Hirsch, Anna K. H.; Engel, Matthias; Hamed, Mostafa M.; Horng, Jim-Tong; Abdel-Halim, Mohammad
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Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-01-01
err0
errOAAI
errKhalifa, Hend; ElHady, Ahmed K.; Liu, Ting; Elgaher, Walid A. M.; Filhol-Cochet, Odile; Cochet, Claude; Abadi, Ashraf H.; Hamed, Mostafa M.; Abdel-Halim, Mohammad; Engel, Matthias
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Targeting the Plasmodium falciparum IspE Enzyme
errACS OMEGA
IF4.3
err2024-10-25
err0
errOAAI
errDiamanti, Eleonora; Steinbach, Annina M.; de Carvalho, Lais P.; Ropponen, Henni-Karoliina; Lacour, Antoine; Hamid, Rawia; Eisa, Sidra; Bravo, Patricia; Bousis, Spyridon; Illarionov, Boris; Fischer, Markus; Hamed, Mostafa M.; Bach, Nina C.; Rottmann, Matthias; Held, Jana; Witschel, Matthias; Sieber, Stephan A.; Hirsch, Anna K. H.
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Discovery and optimization of thiazole-based quorum sensing inhibitors as potent blockers of Pseudomonas aeruginosa pathogenicity
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-10-01
err0
errOAAI
errAbdelsamie, Ahmed S.; Hamed, Mostafa M.; Schuetz, Christian; Roehrig, Teresa; Kany, Andreas M.; Schmelz, Stefan; Blankenfeldt, Wulf; Hirsch, Anna K. H.; Hartmann, Rolf W.; Empting, Martin
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Targeting Plasmodium falciparum IspD in the Methyl-D-erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on Target and Low-Micromolar Whole-Cell Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-20
err1
errOAAI
errWillocx, Daan; Bizzarri, Lorenzo; Alhayek, Alaa; Kannan, Deepika; Bravo, Patricia; Illarionov, Boris; Rox, Katharina; Lohse, Jonas; Fischer, Markus; Kany, Andreas M.; Hahne, Hannes; Rottmann, Matthias; Witschel, Matthias; Odom John, Audrey; Hamed, Mostafa M.; Diamanti, Eleonora; Hirsch, Anna K. H.
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Nanoparticles in liposomes: a platform for increased antibiotic selectivity in multidrug resistant bacteria in respiratory tract infections
errDRUG DELIVERY AND TRANSLATIONAL RESEARCH
IF5.5
err2024-07-24
err0
errOAAI
errFakhoury, Nathalie E.; Mansour, Samar; Abdel-Halim, Mohammad; Hamed, Mostafa M.; Empting, Martin; Boese, Annette; Loretz, Brigitta; Lehr, Claus-Michael; Tammam, Salma N.
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Hit optimization by dynamic combinatorial chemistry on Streptococcus pneumoniae energy-coupling factor transporter ECF-PanT
errCHEMICAL COMMUNICATIONS
IF4.2
err2024-01-01
err2
errOAAI
errExapicheidou, Ioulia Antonia; Shams, Atanaz; Ibrahim, Hamza; Tsarenko, Aleksei; Backenkoehler, Michael; Hamed, Mostafa M.; Diamanti, Eleonora; Volkamer, Andrea; Slotboom, Dirk J.; Hirsch, Anna K. H.
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Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle
errADVANCED SCIENCE
IF14.1
err2023-01-03
err13
errOAAI
errHamed, Mostafa M.; Abdelsamie, Ahmed S.; Rox, Katharina; Schuetz, Christian; Kany, Andreas M.; Roehrig, Teresa; Schmelz, Stefan; Blankenfeldt, Wulf; Arce-Rodriguez, Alejandro; Borrero-de Acuna, Jose Manuel; Jahn, Dieter; Rademacher, Jessica; Ringshausen, Felix C.; Cramer, Nina; Tuemmler, Burkhard; Hirsch, Anna K. H.; Hartmann, Rolf W.; Empting, Martin
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Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors
errPHARMACEUTICALS
IF4.8
err2022-06-22
err3
errOAAI
errDarwish, Sarah S.; Chen, Po-Jen; Hamed, Mostafa M.; Wagdy, Reem A.; Chen, Shun-Hua; Abadi, Ashraf H.; Abdel-Halim, Mohammad; Hwang, Tsong-Long; Engel, Matthias
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Structure-Guided Optimization of Small-Molecule Folate Uptake Inhibitors Targeting the Energy-Coupling Factor Transporters
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-06-16
err4
errOAAI
errKiefer, Alexander F.; Bousis, Spyridon; Hamed, Mostafa M.; Diamanti, Eleonora; Haupenthal, Joerg; Hirsch, Anna K. H.
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Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors
errPHARMACEUTICALS
IF4.8
err2022-05-20
err2
errOAAI
errHamdy, Jehad; Emadeldin, Nouran; Hamed, Mostafa M.; Frakolaki, Efseveia; Katsamakas, Sotirios; Vassilaki, Niki; Zoidis, Grigoris; Hirsch, Anna K. H.; Abdel-Halim, Mohammad; Abadi, Ashraf H.
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Redesigning of the cap conformation and symmetry of the diphenylethyne core to yield highly potent pan-genotypic NS5A inhibitors with high potency and high resistance barrier
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2022-02-01
err2
PREAI
errAbdallah, Mennatallah; Hamed, Mostafa M.; Frakolaki, Efseveia; Katsamakas, Sotirios; Vassilaki, Niki; Bartenschlager, Ralf; Zoidis, Grigoris; Hirsch, Anna K. H.; Abdel-Halim, Mohammad H.; Abadi, Ashraf
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Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class
errCHEMMEDCHEM
IF3.4
err2022-01-11
err6
errOAAI
errDiamanti, Eleonora; Hamed, Mostafa M.; Lacour, Antoine; Bravo, Patricia; Illarionov, Boris; Fischer, Markus; Rottmann, Matthias; Witschel, Matthias; Hirsch, Anna K. H.
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Divergent synthesis and biological evaluation of 2-(trifluoromethyl) pyridines as virulence-attenuating inverse agonists targeting PqsR
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2021-12-01
err10
PREAI
errSchutz, Christian; Hodzic, Amir; Hamed, Mostafa; Abdelsamie, Ahmed S.; Kany, Andreas M.; Bauer, Maximilian; Rohrig, Teresa; Schmelz, Stefan; Scrima, Andrea; Blankenfeldt, Wulf; Empting, Martin
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Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners
errMOLECULES
IF4.6
err2021-08-14
err8
errOAAI
errFrank, Nicolas A.; Szeles, Mario; Akone, Sergi H.; Rasheed, Sari; Huettel, Stephan; Frewert, Simon; Hamed, Mostafa M.; Herrmann, Jennifer; Schuler, Soeren M. M.; Hirsch, Anna K. H.; Mueller, Rolf
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Ralf Bartenschlager
H-index: 122 · Papers: 686
C
Claus‐Michael Lehr
H-index: 95 · Papers: 629
R
Rolf Müller
H-index: 94 · Papers: 1.2K
U
Ute Hentschel
H-index: 80 · Papers: 350
R
Robert Bals
H-index: 74 · Papers: 916
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