Philip Jones - Publications, H-index & Citations

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Philip Jones

The University of Texas MD Anderson Cancer Center

45H-index

223Paper Count

7.8KCitation Count

Published Papers 68

Publication Date

Nivolumab plus ipilimumab induce hyper-progression in renal medullary carcinoma: results of a phase II trial and preclinical evidence

Nature Communications

IF15.7

2025-11-25

OAAI

Melinda Soeung; Xinmiao Yan; Ciro Zanca; Jing Qian; Menuka Karki; Fei Duan; Hania Khan; Li Zhang; David H. Peng; Mariah Williams; Rong He; Ziheng Chen; Luigi Perelli; Jianfeng Chen; Rebecca S. Tidwell; Pankaj K. Chauhan; Courtney N. Le; Truong N. A. Lam; Nirjar Bhattacharya; Rutvi Shah; I-Lin Ho; Jason P. Gay; Caroline C. Carrillo; Ningping Feng; Kang Le; Guang Gao; Teresa L. Perry; Faika Mseeh; Yongying Jiang; Quanyun A. Xu; Niki Marie Zacharias; Rahul A. Sheth; Tharakeswara K. Bathala; Priya Rao; Najat C. Daw; Durga N. Tripathi; Cheryl L. Walker; Mohammad M. Mohammad; Jianhua Zhang; Guangchun Han; Yanshuo Chu; Ruiping Wang; Minghao Dang; Enyu Dai; Fuduan Peng; Yunhe Liu; Akshaya Jadhav; Wenhua Lang; Claudio A. Arrechedera; Leticia Campos Clemente; Edwin R. Parra; Hsinyi Lu; Cara L. Haymaker; Ignacio I. Wistuba; Andrew Futreal; Andrea Viale; Michael J. Soth; Philip Jones; Joseph R. Marszalek; Timothy Heffernan; Giulio F. Draetta; Nizar M. Tannir; Jianjun Gao; Linghua Wang; Giannicola Genovese; Pavlos Msaouel

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Introduction to the themed collection on kinases

RSC Med. Chem.

IF3.6

2025-09-27

OAAI

Meizhong Jin; Hayley Binch; David E. Heppner; Philip Jones

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Discovery of ART0380, a Potent and Selective ATR Kinase Inhibitor Undergoing Phase 2 Clinical Studies for the Treatment of Advanced or Metastatic Solid Cancers

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-12-04

PREAI

Carroll, Christopher L.; Johnson, Michael G.; Ding, Yanbing; Kang, Zhijun; Vijayan, R. S. K.; Bardenhagen, Jennifer P.; Fang, Cheng; Lapointe, David; Li, Meng; Liu, Chiu-Yi; Lv, Xiaobing; Ma, Xiaoyan; Pang, Jihai; Shepard, Hannah E.; Suarez, Catalina; Yau, Anne Ju; Williams, Christopher C.; Wu, Qi; Heald, Robert A.; Robinson, Helen M. R.; Smith, Graeme C. M.; Cross, Jason B.; Do, Mary K. Geck; Jiang, Yongying; Lively, Sarah; Yap, Timothy A.; Giuliani, Virginia; Heffernan, Timothy; Jones, Philip; Di Francesco, M. Emilia

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Evolution from quasivibrational to quasirotational structure in 155Tm and yrast 27/2- to 25/2- energy anomaly in the A ≈ 150 mass region (vol 97, 044306, 2018)

PHYSICAL REVIEW C

IF3.4

2024-11-19

OAAI

Liu, L.; Wang, S. Y.; Wang, S.; Hua, H.; Zhang, S. Q.; Meng, J.; Bark, R. A.; Wyngaardt, S. M.; Qi, B.; Sun, D. P.; Liu, C.; Li, Z. Q.; Jia, H.; Li, X. Q.; Xu, C.; Li, Z. H.; Sun, J. J.; Zhu, L. H.; Jones, P.; Lawrie, E. A.; Lawrie, J. J.; Wiedeking, M.; Bucher, T. D.; Dinoko, T.; Makhathini, L.; Majola, S. N. T.; Noncolela, S. P.; Shirinda, O.; Gal, J.; Kalinka, G.; Molnar, J.; Nyako, B. M.; Timar, J.; Juhasz, K.; Arogunjo, M.

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CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer

JCI INSIGHT

IF6.1

2024-09-17

OAAI

Yuan, Xueying; Hao, Xiaoxin; Chan, Hilda L.; Zhao, Na; Pedroza, Diego A.; Liu, Fengshuo; Le, Kang; Smith, Alex J.; Calderon, Sebastian J.; Lieu, Nadia; Soth, Michael J.; Jones, Philip; Zhang, Xiang H. F.; Rosen, Jeffrey M.

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IACS-16559, a CBP/P300 bromodomain inhibitor for the treatment of specific AML subsets

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Zanca, Ciro; Soth, Michael; Gao, Guang; Gay, Jason; Feng, Ningping; Bristow, Christopher; Le, Kang; Xu, Quanyun; Phuong Nguyen; Jiang, Yongying; Perry, Teresa; Mseeh, Faika; Leonard, Paul; Cross, Jason; Giuliani, Virginia; Marszalek, Joe; Jones, Philip; Heffernan, Tim

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Epigenetic reprogramming by CBP/P300 bromodomain inhibition of triple-negative breast cancer and the immune microenvironment

CANCER RESEARCH

IF16.6

2024-02-01

PREAI

Yuan, Xueying; Soth, Michael; Zhao, Na; Jones, Philip; Rosen, Jeffrey

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TAAR1 agonists improve glycemic control, reduce body weight and modulate neurocircuits governing energy balance and feeding

MOLECULAR METABOLISM

IF6.6

2024-02-01

OAAI

Dedic, Nina; Wang, Lien; Hajos-Korcsok, Eva; Hecksher-Sorensen, Jacob; Roostalu, Urmas; Vickers, Steven P.; Wu, Serena; Anacker, Christoph; Synan, Colleen; Jones, Philip G.; Milanovic, Snezana; Hopkins, Seth C.; Bristow, Linda J.; Koblan, Kenneth S.

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Modulating mitochondria metabolism to radiosensitize KEAP1 mutated non-small cell lung cancer

CANCER RESEARCH

IF16.6

2024-01-09

PREAI

Bright, Scott J.; Kolachina, Rishab; Ben Kacem, Mariam; Manandhar, Mandira; Jones, Philip; Yap, Timothy A.; Lin, Steven H.; Sawakuchi, Gabriel O.

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Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-07-12

PREAI

Le, Kang; Soth, Michael J. J.; Cross, Jason B. B.; Liu, Gang; Ray, William J. J.; Ma, Jiacheng; Goodwani, Sunil G. G.; Acton, Paul J. J.; Buggia-Prevot, Virginie; Akkermans, Onno; Barker, John; Conner, Michael L. L.; Jiang, Yongying; Liu, Zhen; McEwan, Paul; Warner-Schmidt, Jennifer; Xu, Alan; Zebisch, Matthias; Heijnen, Cobi J. J.; Abrahams, Brett; Jones, Philip

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TAAR1 Agonist Ulotaront Improves Glycemic Control and Reduces Body Weight in Rodent Models of Diabetes, Obesity, and Iatrogenic Weight Gain

CNS SPECTRUMS

IF4.1

2023-04-14

OAAI

Dedic, Nina; Jones, Philip G.; Hajos-Korcsok, Eva; Synan, Colleen; Wu, Serena; Anacker, Christoph; Vickers, Steve P.; Hecksher-Sorensen, Jacob; Zeni, Courtney; Milanovic, Snezana; Hopkins, Seth C.; Bristow, Linda J.; Koblan, Kenneth S.

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The ATR inhibitor ART0380 shows preclinical efficacy in monotherapy or in combination with gemcitabine, aPD1, PARP inhibitors and topoisomerase 1 poisons

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Majithiya, Jayesh Bhanabhai; Luzarraga, Marina Roy; Newman, Richard; Costales, Paula; Jones, Philip; Di Francesco, Maria Emilia; Giuliani, Virginia; Caroll, Chris; Do, Mary Geck; Heffernan, Tim; Feng, Ningpeng; Ma, XiaoYan; Lively, Sarah; Johnson, Michael G.; Geo, Lerin; Piscitello, Desiree; Rajendra, Eeson; Grinkevich, Vera; Ranzani, Marco; Stockley, Martin; Langford, Gillian; Heald, Robert; Robinson, Helen M.; Smith, Graeme C.

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Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials

NATURE MEDICINE

IF50

2023-01-19

120

OAAI

Yap, Timothy A.; Daver, Naval; Mahendra, Mikhila; Zhang, Jixiang; Kamiya-Matsuoka, Carlos; Meric-Bernstam, Funda; Kantarjian, Hagop M.; Ravandi, Farhad; Collins, Meghan E.; Di Francesco, Maria Emilia; Dumbrava, Ecaterina E.; Fu, Siqing; Gao, Sisi; Gay, Jason P.; Gera, Sonal; Han, Jing; Hong, David S.; Jabbour, Elias J.; Ju, Zhenlin; Karp, Daniel D.; Lodi, Alessia; Molina, Jennifer R.; Baran, Natalia; Naing, Aung; Ohanian, Maro; Pant, Shubham; Pemmaraju, Naveen; Bose, Prithviraj; Piha-Paul, Sarina A.; Rodon, Jordi; Salguero, Carolina; Sasaki, Koji; Singh, Anand K.; Subbiah, Vivek; Tsimberidou, Apostolia M.; Xu, Quanyun A.; Yilmaz, Musa; Zhang, Qi; Li, Yuan; Bristow, Christopher A.; Bhattacharjee, Meenakshi B.; Tiziani, Stefano; Heffernan, Timothy P.; Vellano, Christopher P.; Jones, Philip; Heijnen, Cobi J.; Kavelaars, Annemieke; Marszalek, Joseph R.; Konopleva, Marina

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Targeting RAS Mutant Colorectal Cancer with Dual Inhibition of MEK and CDK4/6

CANCER RESEARCH

IF16.6

2022-08-01

OAAI

Sorokin, Alexey V.; Marie, Preeti Kanikarla; Bitner, Lea; Syed, Muddassir; Woods, Melanie; Manyam, Ganiraju; Kwong, Lawrence N.; Johnson, Benny; Morris, Van K.; Jones, Philip; Menter, David G.; Lee, Michael S.; Kopetz, Scott

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Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome

PLOS GENETICS

IF3.7

2021-12-29

OAAI

Jewell, Brittany L.; Xu, An; Zhu, Dandan; Huang, Mo-Fan A.; Lu, Linchao; Liu, Mo; Underwood, Erica; Park, Jun Hyoung; Fan, Huihui; Gingold, Julian; Zhou, Ruoji; Tu, Jian; Huo, Zijun; Liu, Ying K.; Jin, Weidong A.; Chen, Yi-Hung; Xu, Yitian; Chen, Shu-Hsia K.; Rainusso, Nino; Berg, Nathaniel; Bazer, Danielle; Vellano, Christopher L.; Jones, Philip; Eltzschig, Holger; Zhao, Zhongming; Kaipparettu, Benny Abraham; Zhao, Ruiying; Wang, Lisa; Lee, Dung-Fang

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Ulotaront: A TAAR1 Agonist for the Treatment of Schizophrenia

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2021-12-06

OAAI

Heffernan, Michele L. R.; Herman, Lee W.; Brown, Scott; Jones, Philip G.; Shao, Liming; Hewitt, Michael C.; Campbell, John E.; Dedic, Nina; Hopkins, Seth C.; Koblan, Kenneth S.; Xie, Linghong

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Discovery of 6-[(3S,4S)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-10-13

PREAI

Czako, Barbara; Sun, Yuting; McAfoos, Timothy; Cross, Jason B.; Leonard, Paul G.; Burke, Jason P.; Carroll, Christopher L.; Feng, Ningping; Harris, Angela L.; Jiang, Yongying; Kang, Zhijun; Kovacs, Jeffrey J.; Mandal, Pijus; Meyers, Brooke A.; Mseeh, Faika; Parker, Connor A.; Yu, Simon S.; Williams, Christopher C.; Wu, Qi; Di Francesco, Maria Emilia; Draetta, Giulio; Heffernan, Timothy; Marszalek, Joseph R.; Kohl, Nancy E.; Jones, Philip

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Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer

CANCER RESEARCH

IF16.6

2021-09-13

OAAI

Evans, Kurt W.; Yuca, Erkan; Scott, Stephen S.; Zhao, Ming; Arango, Natalia Paez; Pico, Christian X. Cruz; Saridogan, Turcin; Shariati, Maryam; Class, Caleb A.; Bristow, Christopher A.; Vellano, Christopher P.; Zheng, Xiaofeng; Gonzalez-Angulo, Ana Maria; Su, Xiaoping; Tapia, Coya; Chen, Ken; Akcakanat, Argun; Lim, Bora; Tripathy, Debu; Yap, Timothy A.; Di Francesco, Maria Emilia; Draetta, Giulio F.; Jones, Philip; Heffernan, Timothy P.; Marszalek, Joseph R.; Meric-Bernstam, Funda

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PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma

NATURE COMMUNICATIONS

IF15.7

2021-07-30

OAAI

Giuliani, Virginia; Miller, Meredith A.; Liu, Chiu-Yi; Hartono, Stella R.; Class, Caleb A.; Bristow, Christopher A.; Suzuki, Erika; Sanz, Lionel A.; Gao, Guang; Gay, Jason P.; Feng, Ningping; Rose, Johnathon L.; Tomihara, Hideo; Daniele, Joseph R.; Peoples, Michael D.; Bardenhagen, Jennifer P.; Geck Do, Mary K.; Chang, Qing E.; Vangamudi, Bhavatarini; Vellano, Christopher; Ying, Haoqiang; Deem, Angela K.; Do, Kim-Anh; Genovese, Giannicola; Marszalek, Joseph R.; Kovacs, Jeffrey J.; Kim, Michael; Fleming, Jason B.; Guccione, Ernesto; Viale, Andrea; Maitra, Anirban; Emilia Di Francesco, M.; Yap, Timothy A.; Jones, Philip; Draetta, Giulio; Carugo, Alessandro; Chedin, Frederic; Heffernan, Timothy P.

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Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-07-22

PREAI

Hamilton, Matthew M.; Mseeh, Faika; McAfoos, Timothy J.; Leonard, Paul G.; Reyna, Naphtali J.; Harris, Angela L.; Xu, Alan; Han, Michelle; Soth, Michael J.; Czako, Barbara; Theroff, Jay P.; Mandal, Pijus K.; Burke, Jason P.; Virgin-Downey, Brett; Petrocchi, Alessia; Pfaffinger, Dana; Rogers, Norma E.; Parker, Connor A.; Yu, Simon S.; Jiang, Yongying; Krapp, Stephan; Lammens, Alfred; Trevitt, Graham; Tremblay, Martin R.; Mikule, Keith; Wilcoxen, Keith; Cross, Jason B.; Jones, Philip; Marszalek, Joseph R.; Lewis, Richard T.

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Research Directions