Not logged in Presence of tertiary lymphoid structures and exhausted tissue-resident T cells determines clinical response to PD-1 blockade in renal cell carcinoma Wirth, Lena Vanessa; Hugaboom, Miya B.; Street, Kelly; Ruthen, Neil; Jegede, Opeyemi; Schindler, Nicholas; Shah, Valisha; Zaemes, Jacob; El Ahmar, Nourhan; Matar, Sayed; Savla, Varunika; Choueiri, Toni; Denize, Thomas; West, Destiny; Mcdermott, David F.; Plimack, Elizabeth R.; Sosman, Jeffrey; Haas, Naomi; Hurwitz, Michael E.; Hammers, Hans; Stein, Mark; Alter, Robert; Bilen, Mehmet; Signoretti, Sabina; Atkins, Michael B.; Wu, Catherine J.; Braun, David Share Save
CD163+Tumor-Associated macrophages and clinical outcomes to First-Line nivolumab therapy in patients with metastatic clear cel renal cell carcinoma: insights from the HCRN GU16-260 trial Simsek, Berkay; Paul, Morgan A.; Xie, Wanling; El Ahmar, Nourhan; Matar, Sayed; Laimon, Yasmin Nabil; RobertiDe Oliveira, Gabriel; Mohanna, Razan; Delcea, Andrew; Choueri, Toni; Braun, David; Sun, Maxine; Haas, Naomi B.; Hammers, Hans J.; Bilen, Mehmet; Stein, Mark N.; Sosman, Jeffrey A.; Freeman, Gordon J.; Wu, Catherine; Mcdermott, David; Atkins, Michael B.; Signoretti, Sabina Share Save
Presence of tertiary lymphoid structures and exhausted tissue-resident T cells determines clinical response to PD-1 blockade in renal cell carcinoma Wirth, Lena; Hugaboom, Miya; Street, Kelly; Ruthen, Neil; Jegede, Opeyemi; Schindler, Nicholas; Shah, Valisha; Zaemes, Jacob; El Ahmar, Nourhan; Matar, Sayed; Savla, Varunika; Choueri, Toni; Denize, Thomas; West, Destiny; Mcdermott, David; Plimack, Elizabeth; Sosman, Jeffrey A.; Haas, Naomi B.; Hurwitz, Michael; Hammers, Hans J.; Stein, Mark N.; Alter, Robert; Bilen, Mehmet; Signoretti, Sabina; Atkins, Michael B.; Wu, Catherine; Braun, David Share Save
Tertiary Lymphoid Structures Predict Response to First-Line Nivolumab Therapy in Advanced Renal Cell Carcinoma: Findings from the HCRN GU16-260 Clinical Trial El Ahmar, Nourhan; Simsek, Berkay; Jegede, Opeyemi; Matar, Sayed; Savla, Varunika; Laimon, Yasmin; Mohanna, Razan; De Oliveira, Gabriel Roberti; Sheshdeh, Aseman Baghari; Delcea, Andrew; Paul, Morgan; Choueiri, Toni; Xie, Wanling; Freeman, Gordon; Braun, David; Haas, Naomi Balzer; Hammers, Hans; Bilen, Mehmet; Stein, Mark; Sosman, Jeffrey; Wu, Catherine; Mcdermott, David; Atkins, Michael; Signoretti, Sabina Share Save
AXL Receptor Tyrosine Kinase Expression in Metastatic Renal Cell Carcinoma: Insights from the METEOR trial Laimon, Yasmin; Paul, Morgan; Jammihal, Tejas; Ghandour, Fatme; El Ahmar, Nourhan; Simsek, Berkay; Matar, Sayed; Denize, Thomas; Mohanna, Razan; De Oliveira, Gabriel Roberti; Delcea, Andrew; Shukla, Sachet; Braun, David; Sun, Maxine; Aftab, Dana; Saad, Eddy; Machaalani, Marc; Xie, Wanling; Choueiri, Toni; Signoretti, Sabina Share Save
Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma El Zarif, Talal; Semaan, Karl; Eid, Marc; Seo, Ji-Heui; Garinet, Simon; Davidsohn, Matthew P.; Sahgal, Pranshu; Fortunato, Brad; Canniff, John; Nassar, Amin H.; Alaiwi, Sarah Abou; Bakouny, Ziad; Lakshminarayanan, Gitanjali; Savignano, Hunter; Lyons, Kevin; Matar, Sayed; Ali, Atef; Saad, Eddy; Saliby, Renee Maria; Cordeiro, Paulo; Zhang, Ziwei; Ahmar, Nourhan El; Laimon, Yasmin Nabil; Labaki, Chris; Shah, Valisha; Freeman, Dory; O'Toole, Jillian; Lee, Gwo-Shu Mary; Hwang, Justin; Pomerantz, Mark; Signoretti, Sabina; Allen, Eliezer M. Van; Xie, Wanling; Berchuck, Jacob E.; Viswanathan, Srinivas R.; Braun, David A.; Choueiri, Toni K.; Freedman, Matthew L.; Baca, Sylvan C. Share Save
PD-1 Expression on Intratumoral Regulatory T Cells Is Associated with Lack of Benefit from Anti-PD-1 Therapy in Metastatic Clear-Cell Renal Cell Carcinoma Patients Denize, Thomas; Jegede, Opeyemi A.; Matar, Sayed; El Ahmar, Nourhan; West, Destiny J.; Walton, Emily; Bagheri, Aseman Sheshdeh; Savla, Varunika; Laimon, Yasmin Nabil; Gupta, Saurabh; Vemula, Sai Vikram; Braun, David A.; Burke, Kelly P.; Catalano, Paul J.; Freeman, Gordon J.; Motzer, Robert J.; Atkins, Michael B.; McDermott, David F.; Sharpe, Arlene H.; Choueiri, Toni K.; Signoretti, Sabina Share Save
Regulation of HHLA2 expression in kidney cancer and myeloid cells Shigemura, Tomonari; Perrot, Nahuel; Huang, Zimo; Bhatt, Rupal S.; Sheshdeh, Aseman Bagheri; Ahmar, Nourhan El; Ghandour, Fatme; Signoretti, Sabina; Mcdermott, David F.; Freeman, Gordon J.; Mahoney, Kathleen M. Share Save
Determinants of exceptional response to immune checkpoint inhibition in metastatic clear cell renal cell carcinoma Saliby, R. M.; Jammihal, T.; Labaki, C.; Soulati, H.; Gallegos, J.; Peris, A.; McCurry, D.; Yu, C.; Shah, V.; Poduval, D.; El Zarif, T.; El Ahmar, N.; Laimon, Y. N.; Heng, D. Y. C.; Signoretti, S.; Van Allen, E. M.; Choueiri, T. K.; Shukla, S.; Braun, D. A. Share Save
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Epigenomic profiling nominates master transcription factors (TFs) driving sarcomatoid differentiation of renal cell carcinoma (RCC) Semaan, Karl; El Zarif, Talal; Eid, Marc; Shah, Valisha; Fortunato, Brad; Saliby, Renee Maria; Nassar, Amin H.; Abou Alaiwi, Sarah; Seo, Ji-Heui; Labaki, Chris; Bakouny, Ziad; Matar, Sayed; El Ahmar, Nourhan; Laimon, Yasmin Nabil; Lee, Gwo-Shu Mary; Pomerantz, Mark; Berchuck, Jacob; Signoretti, Sabina; Van Allen, Eliezer; Choueiri, Toni; Braun, David; Freedman, Matthew; Baca, Sylvan Share Save
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