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Optimization of Single Relaxin B-Chain Peptide Leads to the Identification of R2R01, a Potent, Long-Acting RXFP1 Agonist for Cardiovascular and Renal Diseases Mallart, Sergio; Ingenito, Raffaele; Magotti, Paola; Bresciani, Alberto; Di Marco, Annalise; Esposito, Simone; Monteagudo, Edith; Caretti, Fulvia; Orsatti, Laura; Santoprete, Alessia; Roversi, Daniela; Tucci, Federica; Veneziano, Maria; Brasseur, Denis; Chenede, Xavier; Corbier, Alain; Gauzy-Lazo, Laurence; Gervat, Vincent; Marguet, Frank; Minoletti, Claire; Pasquier, Olivier; Poirier, Bruno; Azam, Aurelien; Maillere, Bernard; Bianchi, Elisabetta; Janiak, Philip; Duclos, Olivier; Illiano, Stephane Share Save
Discovery of I-1000233, a potent, selective and brain permeable SHP2 allosteric inhibitor Puca, Francesca; Fabbrini, Danilo; Ciammaichella, Alina; Missineo, Antonino; Bisbocci, Monica; Nibbio, Martina; Di Marco, Annalise; Apicella, Claudia; Colaceci, Fabrizio; Sasso, Romina; Natale, Daniela; Scalabri, Francesco; Alli, Cristina; Pucci, Vincenzo; Montalbetti, Christian; Petrocchi, Alessia; Carugo, Alessandro; Toniatti, Carlo Share Save
Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors Torrente, Esther; Fodale, Valentina; Ciammaichella, Alina; Ferrigno, Federica; Ontoria, Jesus M.; Ponzi, Simona; Rossetti, Ilaria; Sferrazza, Alessio; Amaudrut, Jerome; Missineo, Antonino; Esposito, Simone; Palombo, Simone; Nibbio, Martina; Cerretani, Mauro; Bisbocci, Monica; Cellucci, Antonella; di Marco, Annalise; Alli, Cristina; Pucci, Vincenzo; Toniatti, Carlo; Petrocchi, Alessia Share Save
Transport of cationic liposomes in a human blood brain barrier model: Role of the stereochemistry of the gemini amphiphile on liposome biological features Simonis, Beatrice; Vignone, Domenico; Paz, Odalys Gonzalez; Donati, Enrica; Falchetti, Maria Laura; Bombelli, Cecilia; Cellucci, Antonella; Auciello, Giulio; Fini, Ivan; Galantini, Luciano; Syeda, Rudaba Zaman; Mazzonna, Marco; Mongiardi, Maria Patrizia; Buonocore, Francesco; Ceccacci, Francesca; Di Marco, Annalise; Mancini, Giovanna Share Save
Cyclic Phosphopantothenic Acid Prodrugs for Treatment of Pantothenate Kinase-Associated Neurodegeneration Auciello, Giulio; Di Marco, Annalise; Paz, Odalys Gonzalez; Malancona, Savina; Harper, Steven; Beconi, Maria; Rossetti, Ilaria; Ciammaichella, Alina; Fezzardi, Paola; Vecchi, Andrea; Bracacel, Elena; Cicero, Daniel; Monteagudo, Edith; Elbaum, Daniel Share Save
Establishment of an in Vitro Human Blood-Brain Barrier Model Derived from Induced Pluripotent Stem Cells and Comparison to a Porcine Cell-Based System Di Marco, Annalise; Vignone, Domenico; Paz, Odalys Gonzalez; Fini, Ivan; Battista, Maria Rosaria; Cellucci, Antonella; Bracacel, Elena; Auciello, Giulio; Veneziano, Maria; Khetarpal, Vinod; Rose, Mark; Rosa, Alessandro; Gloaguen, Isabelle; Monteagudo, Edith; Herbst, Todd; Dominguez, Celia; Munoz-Sanjuan, Ignacio Share Save
5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein Malancona, Savina; Mori, Mattia; Fezzardi, Paola; Santoriello, Marisabella; Basta, Andreina; Nibbio, Martina; Kovalenko, Lesia; Speziale, Roberto; Battista, Maria Rosaria; Cellucci, Antonella; Gennari, Nadia; Monteagudo, Edith; Di Marco, Annalise; Giannini, Alessia; Sharma, Rajhans; Pires, Manuel; Real, Eleonore; Zazzi, Maurizio; Lang, Maria Chiara Dasso; De Forni, Davide; Saladini, Francesco; Mely, Yves; Summa, Vincenzo; Harper, Steven; Botta, Maurizio Share Save
Synthesis and Biological Evaluation of RGD-Cryptophycin Conjugates for Targeted Drug Delivery Borbely, Adina; Figueras, Eduard; Martins, Ana; Esposito, Simone; Auciello, Giulio; Monteagudo, Edith; Di Marco, Annalise; Summa, Vincenzo; Cordella, Paola; Perego, Raffaella; Kemker, Isabell; Frese, Marcel; Gallinari, Paola; Steinkuehler, Christian; Sewald, Norbert Share Save
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1H-pyrrolyl)(phenyl)methyl-1H-innidazole Derivatives as Antiprotozoal Agents Saccoliti, Francesco; Madia, Valentina Noemi; Tudino, Valeria; De Leo, Alessandro; Pescatori, Luca; Messore, Antonella; De Vita, Daniela; Scipione, Luigi; Brun, Reto; Kaiser, Marcel; Maser, Pascal; Calvet, Claudia M.; Jennings, Gareth K.; Podust, Larissa M.; Pepe, Giacomo; Cirilli, Roberto; Faggi, Cristina; Di Marco, Annalise; Battista, Maria Rosaria; Summa, Vincenzo; Costi, Roberta; Di Santo, Roberto Share Save
Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides Bresciani, Alberto; Ontoria, Jesus M.; Biancofiore, Ilaria; Cellucci, Antonella; Ciammaichella, Alina; Di Marco, Annalise; Ferrigno, Federica; Francone, Alessandra; Malancona, Savina; Monteagudo, Edith; Nizi, Emanuela; Pace, Paola; Ponzi, Simona; Rossetti, Ilaria; Veneziano, Maria; Summa, Vincenzo; Harper, Steven Share Save
Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs Ontoria, Jesus M.; Paonessa, Giacomo; Ponzi, Simona; Ferrigno, Federica; Nizi, Emanuela; Biancofiore, Ilaria; Malancona, Savina; Graziani, Rita; Roberts, David; Willis, Paul; Bresciani, Alberto; Gennari, Nadia; Cecchetti, Ottavia; Monteagudo, Edith; Orsale, Maria V.; Veneziano, Maria; Di Marco, Annalise; Cellucci, Antonella; Laufer, Ralph; Altamura, Sergio; Summa, Vincenzo; Harper, Steven Share Save
PEGylation of Neuromedin U yields a promising candidate for the treatment of obesity and diabetes Ingallinella, Paolo; Peier, Andrea M.; Pocai, Alessandro; Di Marco, Annalise; Desai, Kunal; Zytko, Karolina; Qian, Ying; Du, Xiaobing; Cellucci, Antonella; Monteagudo, Edith; Laufer, Ralph; Bianchi, Elisabetta; Marsh, Donald J.; Pessi, Antonello Share Save
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Identification of Novel, Selective, and Stable Inhibitors of Class II Histone Deacetylases. Validation Studies of the Inhibition of the Enzymatic Activity of HDAC4 by Small Molecules as a Novel Approach for Cancer Therapy Ontoria, Jesus M.; Altamura, Sergio; Di Marco, Annalise; Ferrigno, Federica; Laufer, Ralph; Muraglia, Ester; Palumbi, Maria Cecilia; Rowley, Michael; Scarpelli, Rita; Schultz-Fademrecht, Carsten; Scrafini, Sergio; Steinkuehler, Christian; Jones, Philip Share Save
Cyclic phosphoramidates as prodrugs of 2′-C-methylcytidine Meppen, Malte; Pacini, Barbara; Bazzo, Renzo; Koch, Uwe; Leone, Joseph F.; Koeplinger, Kenneth A.; Rowley, Michael; Altamura, Sergio; Di Marco, Annalise; Fiore, Fabrizio; Giuliano, Claudio; Gonzalez-Paz, Odalys; Laufer, Ralph; Pucci, Vincenzo; Narjes, Frank; Gardelli, Cristina Share Save
Phosphoramidate Prodrugs of 2′-C-Methylcytidine for Therapy of Hepatitis C Virus Infection Gardelli, Cristina; Attenni, Barbara; Donghi, Monica; Meppen, Malte; Pacini, Barbara; Harper, Steven; Di Marco, Annalise; Fiore, Fabrizio; Giuliano, Claudio; Pucci, Vincenzo; Laufer, Ralph; Gennari, Nadia; Marcucci, Isabella; Leone, Joseph F.; Olsen, David B.; MacCoss, Malcolm; Rowley, Michael; Narjes, Frank Share Save
Design and synthesis of bicyclic pyrimidinones as potent and orally bioavailable HIV-1 integrase inhibitors Muraglia, Ester; Kinzel, Olaf; Gardelli, Cristina; Crescenzi, Benedetta; Donghi, Monica; Ferrara, Marco; Nizi, Emanuela; Orvieto, Federica; Pescatore, Giovanna; Laufer, Ralph; Gonzalez-Paz, Odalys; Di Marco, Annalise; Fiore, Fabrizio; Monteagudo, Edith; Fonsi, Massimiliano; Felock, Peter J.; Rowley, Michael; Summa, Vincenzo Share Save
Enhancing B- and T-cell immune response to a hepatitis C virus E2 DNA vaccine by intramuscular electrical gene transfer Zucchelli, S; Capone, S; Fattori, E; Folgori, A; Di Marco, A; Casimiro, D; Simon, AJ; Laufer, R; La Monica, N; Cortese, R; Nicosia, A Share Save
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