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Anti-mitotic agent SB-216 overcomes taxane resistance in castration-resistant prostate cancer and exhibits anti-tumour efficacy in pancreatic cancer Wang, Rui; Cai, Chun; Deng, Shanshan; Xie, Yang; Pochampally, Satyanarayana; Hamilton, David J.; Meibohm, Bernd; Glazer, Evan S.; Miller, Duane D.; Li, Wei Share Save
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The antiviral BDGR-49 provides protection from lethal, neurotropic Venezuelan equine encephalitis virus intranasal infection in mice Williams, Evan P.; Xue, Yi; Vogel, Peter; Yang, Dong; Ponce-Flores, Alejandro; Li, Xiaoyu; Ogorek, Tyler J.; Saini, Manisha; Iulek, Jorge; Ruiz, Francesc Xavier; Arnold, Eddy; Golden, Jennifer E.; Meibohm, Bernd; Jonsson, Colleen B. Share Save
Discovery of a potent and selective TRPC3 antagonist with neuroprotective effects Wang, Jiaxing; Zhang, Sicheng; Boda, Vijay K.; Chen, Hao; Park, Hyunseo; Parmar, Keyur; Ma, Dejian; Miller, Duane D.; Meibohm, Bernd; Du, Jianyang; Liao, Francesca-Fang; Wu, Zhongzhi; Li, Wei Share Save
Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis Bauman, Allison A.; Sarathy, Jansy P.; Kaya, Firat; Massoudi, Lisa M.; Scherman, Michael S.; Hastings, Courtney; Liu, Jiuyu; Xie, Min; Brooks, Elizabeth J.; Ramey, Michelle E.; Jones, Isabelle L.; Benedict, Noalani D.; Maclaughlin, Madelyn R.; Miller-Dawson, Jake A.; Waidyarachchi, Samanthi L.; Butler, Michelle M.; Bowlin, Terry L.; Zimmerman, Matthew D.; Lenaerts, Anne J.; Meibohm, Bernd; Gonzalez-Juarrero, Mercedes; Lyons, Michael A.; Dartois, Veronique; Lee, Richard E.; Robertson, Gregory T. Share Save
A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides Ali, Malik Zohaib; Dutt, Taru S.; MacNeill, Amy; Walz, Amanda; Pearce, Camron; Lam, Ha; Philp, Jamie S.; Patterson, Johnathan; Henao-Tamayo, Marcela; Lee, Richard; Liu, Jiuyu; Robertson, Gregory T.; Hickey, Anthony J.; Meibohm, Bernd; Juarrero, Mercedes Gonzalez Share Save
Translational modelling to predict human pharmacokinetics and pharmacodynamics of a Bruton's tyrosine kinase-targeted protein degrader BGB-16673 Wu, Yue; Meibohm, Bernd; Zhang, Taichang; Hou, Xinfeng; Wang, Haitao; Sun, Xiaona; Jiang, Ming; Zhang, Bo; Zhang, Wenjing; Liu, Ye; Jin, Wei; Wang, Fan Share Save
Biological activity of a stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor, 60c, in metastatic, triple-negative breast cancer Oluwalana, Damilola; Adeleye, Kelli L.; Krutilina, Raisa I.; Chen, Hao; Playa, Hilaire; Deng, Shanshan; Parke, Deanna N.; Abernathy, John; Middleton, Leona; Cullom, Alexandra; Thalluri, Bhargavi; Ma, Dejian; Meibohm, Bernd; Miller, Duane D.; Seagroves, Tiffany N.; Li, Wei Share Save
TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate cardiac allograft survival Miura, Shuhei; Habibabady, Zahra A.; Pollok, Franziska; Ma, Madelyn; Rosales, Ivy A.; Kinoshita, Kohei; Pratts, Shannon; McGrath, Gannon; Chaban, Ryan; Fogarty, Siobhan; Meibohm, Bernd; Daugherty, Bruce; Lederman, Seth; Pierson III, Richard N. Share Save
TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate renal allograft survival Lassiter, Grace; Otsuka, Ryo; Hirose, Takayuki; Rosales, Ivy; Karadagi, Ahmad; Tomosugi, Toshihide; Dehnadi, Abbas; Lee, Hang; Colvin, Robert B.; Baardsnes, Jason; Moraitis, Anna; Smith, Emma E.; Ali, Zahida; Berhe, Phil; Mulder, Andrew; Meibohm, Bernd; Daugherty, Bruce; Fogarty, Siobhan; Pierson, Richard N.; Lederman, Seth; Kawai, Tatsuo Share Save
Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics Parmar, Keyur R.; Lukka, Pradeep B.; Wagh, Santosh; Temrikar, Zaid H.; Liu, Jiuyu; Lee, Richard E.; Braunstein, Miriam; Hickey, Anthony J.; Robertson, Gregory T.; Gonzalez-Juarrero, Mercedes; Edginton, Andrea; Meibohm, Bernd Share Save
Barriers to global pharmacometrics: educational challenges and opportunities across the globe Michelet, Robin; Aulin, Linda B. S.; Borghardt, Jens M. M.; Dalla Costa, Teresa; Denti, Paolo; Ibarra, Manuel; Ma, Guangda; Meibohm, Bernd; Pillai, Goonaseelan (Colin); Schmidt, Stephan; Hennig, Stefanie; Kloft, Charlotte Share Save
SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis Deng, Shanshan; Banerjee, Souvik; Chen, Hao; Pochampally, Satyanarayana; Wang, Yuxi; Yun, Mi-Kyung; White, Stephen W.; Parmar, Keyur; Meibohm, Bernd; Hartman, Kelli L.; Wu, Zhongzhi; Miller, Duane D.; Li, Wei Share Save
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Colchicine-Binding Site Agent CH-2-77 as a Potent Tubulin Inhibitor Suppressing Triple-Negative Breast Cancer Deng, Shanshan; Krutilina, Raisa I.; Hartman, Kelli L.; Chen, Hao; Parke, Deanna N.; Wang, Rui; Mahmud, Foyez; Ma, Dejian; Lukka, Pradeep B.; Meibohm, Bernd; Seagroves, Tiffany N.; Miller, Duane D.; Li, Wei Share Save
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