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Modeling serum M-protein response for early detection of biochemical relapse in myeloma patients treated with bortezomib, lenalidomide and dexamethasone Otani, Yuki; Zhao, Yunqi; Wang, Guanyu; Labotka, Richard; Rogge, Mark; Gupta, Neeraj; Vakilynejad, Majid; Bottino, Dean; Tanigawara, Yusuke Share Save
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Heterogeneity in Vaccinal Immunity to SARS-CoV-2 Can Be Addressed by a Personalized Booster Strategy Stoddard, Madison; Yuan, Lin; Sarkar, Sharanya; Mangalaganesh, Shruthi; Nolan, Ryan P.; Bottino, Dean; Hather, Greg; Hochberg, Natasha S.; White, Laura F.; Chakravarty, Arijit Share Save
From Cold to Hot: Changing Perceptions and Future Opportunities for Quantitative Systems Pharmacology Modeling in Cancer Immunotherapy Lemaire, Vincent; Bassen, David; Reed, Mike; Song, Roy; Khalili, Samira; Lien, Yi Ting Kayla; Huang, Lu; Singh, Aman P.; Stamatelos, Spyros; Bottino, Dean; Hua, Fei Share Save
CONDITIONAL BISPECIFIC T CELL ENGAGER DESIGN AND DOSING OPTIMIZATION VIA MECHANISTIC MODELING Wu, Jess; Vilkhovoy, Michael; Shum, Sara; Chouitar, Johara; Leroy, Patrick; Fridman, Leticia; Kwok, Eilene; Wu, Glendon; Ecsedi, Matyas; Banerjee, Antara; Bottino, Dean Share Save
Quantitative Systems Pharmacology Approaches for Immuno-Oncology: Adding Virtual Patients to the Development Paradigm Chelliah, Vijayalakshmi; Lazarou, Georgia; Bhatnagar, Sumit; Gibbs, John P.; Nijsen, Marjoleen; Ray, Avijit; Stoll, Brian; Thompson, R. Adam; Gulati, Abhishek; Soukharev, Serguei; Yamada, Akihiro; Weddell, Jared; Sayama, Hiroyuki; Oishi, Masayo; Wittemer-Rump, Sabine; Patel, Chirag; Niederalt, Christoph; Burghaus, Rolf; Scheerans, Christian; Lippert, Joerg; Kabilan, Senthil; Kareva, Irina; Belousova, Natalya; Rolfe, Alex; Zutshi, Anup; Chenel, Marylore; Venezia, Filippo; Fouliard, Sylvain; Oberwittler, Heike; Scholer-Dahirel, Alix; Lelievre, Helene; Bottino, Dean; Collins, Sabrina C.; Nguyen, Hoa Q.; Wang, Haiqing; Yoneyama, Tomoki; Zhu, Andy Z. X.; van der Graaf, Piet H.; Kierzek, Andrzej M. Share Save
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Evaluation of large-scale quantitative systems pharmacology model predictions of in vitro cancer cell line sensitivity to TAK-659, an investigational oral spleen tyrosine kinase (SYK) inhibitor Abbasi, Taher; Vali, Shireen; Williams, Miguel; Sappal, Jessica; Li, Cong; Shin, Hyunjin; Gregory, Rick; Wu, Yujun; Wang, Shining; Stumpo, Kate; Bottino, Dean Share Save
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Transforming Translation Through Quantitative Pharmacology for High-Impact Decision Making in Drug Discovery and Development Gupta, Neeraj; Bottino, Dean; Simonsson, Ulrika S. H.; Musante, Cynthia J.; Bueters, Tjerk; Rieger, Theodore R.; Macha, Sreeraj; Chenel, Marylore; Fancourt, Craig; Kanodia, Jitendra; Nayak, Satyaprakash Share Save
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