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Glue-Tiful Inhibitors: Cyclic Depsipeptides Enhance Protein-Protein Interaction within the Subunits Heterotrimeric Gq/11 Proteins Juergenliemke, Lars; Alenfelder, Judith; Schihada, Hannes; Muhle, Jonas; Rodrigues, Matthew j.; Guixa-gonzalez, Ramon; Crusemann, Max; Konig, Gabriele m.; Schertler, Gebhard fx.; Kostenis, Evi; Deupi, Xavier Share Save
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Discovery of Anthranilic Acid Derivatives as Antagonists of the Pro-Inflammatory Orphan G Protein-Coupled Receptor GPR17 Boshta, Nader M.; Lewash, Michael; Koese, Meryem; Namasivayam, Vigneshwaran; Sarkar, Soumya; Voss, Jan H.; Liedtke, Andy J.; Junker, Anna; Tian, Maoqun; Stoessel, Anne; Rashed, Mahmoud; Mahal, Ahmed; Merten, Nicole; Pegurier, Cecile; Hockemeyer, Jo''rg; Kostenis, Evi; Mueller, Christa E. Share Save
Development of a NanoBRET Assay Platform to Detect Intracellular Ligands for the Chemokine Receptors CCR6 and CXCR1 Huber, Max E.; Wurnig, Silas L.; Moumbock, Aurelien F. A.; Toy, Lara; Kostenis, Evi; Bartolome, Ana Alonso; Szpakowska, Martyna; Chevigne, Andy; Gunther, Stefan; Hansen, Finn K.; Schiedel, Matthias Share Save
Pharmacological Gq inhibition induces strong pulmonary vasorelaxation and reverses pulmonary hypertension Seidinger, Alexander; Roberts, Richard; Bai, Yan; Mueller, Marion; Pfeil, Eva; Matthey, Michaela; Rieck, Sarah; Alenfelder, Judith; Koenig, Gabriele M.; Pfeifer, Alexander; Kostenis, Evi; Klinke, Anna; Fleischmann, Bernd K.; Wenzel, Daniela Share Save
GRK specificity and Gβγ dependency determines the potential of a GPCR for arrestin-biased agonism Matthees, Edda S. F.; Filor, Jenny C.; Jaiswal, Natasha; Reichel, Mona; Youssef, Noureldine; D'Uonnolo, Giulia; Szpakowska, Martyna; Drube, Julia; Koenig, Gabriele M.; Kostenis, Evi; Chevigne, Andy; Godbole, Amod; Hoffmann, Carsten Share Save
A MassQL-Integrated Molecular Networking Approach for the Discovery and Substructure Annotation of Bioactive Cyclic Peptides Berger, Tim; Alenfelder, Judith; Steinmueller, Sophie; Heimann, Dominik; Gohain, Namrata; Petras, Daniel; Wang, Mingxun; Berger, Robert; Kostenis, Evi; Reher, Raphael Share Save
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A human obesity-associated MC4R mutation with defective Gq/11α signaling leads to hyperphagia in mice Metzger, Peter J.; Zhang, Aileen; Carlson, Bradley A.; Sun, Hui; Cui, Zhenzhong; Li, Yongqi; Jahnke, Marshal T.; Layton, Daniel R.; Gupta, Meenakshi B.; Liu, Naili; Kostenis, Evi; Gavrilova, Oksana; Chen, Min; Weinstein, Lee S. Share Save
Reply to: How carvedilol does not activate β2-adrenoceptors Kostenis, Evi; Gomeza, Jesus; Miess-Tanneberg, Elke; Blum, Nina Kathleen; Benkel, Tobias; Chevigne, Andy; Hoffmann, Carsten; Kolb, Peter; Nikolaev, Viacheslav; Waldhoer, Maria; Szpakowska, Martyna; Inoue, Asuka; Schulz, Stefan Share Save
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Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets Lorza-Gil, Estela; Kaiser, Gabriele; Carlein, Christopher; Hoffmann, Markus D. A.; Koenig, Gabriele M.; Haug, Sieglinde; Roma, Leticia Prates; Ulven, Elisabeth Rexen; Ulven, Trond; Kostenis, Evi; Birkenfeld, Andreas L.; Haering, Hans-Ulrich; Ullrich, Susanne; Gerst, Felicia Share Save
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Selective optogenetic control of Gq signaling using human Neuropsin (vol 13, 1765, 2022) Wagdi, Ahmed; Malan, Daniela; Sathyanarayanan, Udhayabhaskar; Beauchamp, Janosch S.; Vogt, Markus; Zipf, David; Beiert, Thomas; Mansuroglu, Berivan; Dusend, Vanessa; Meininghaus, Mark; Schneider, Linn; Kalthof, Bernd; Wiegert, J. Simon; Koenig, Gabriele M.; Kostenis, Evi; Patejdl, Robert; Sasse, Philipp; Bruegmann, Tobias Share Save
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