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R

Rosa Purgatorio

universita degli studi di bari aldo moro

15H-index
55Paper Count
833Citation Count
Published Papers 36
Publication Date
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Exploring Pyrazolidinone and Pyrazolidinedione Scaffolds for Alzheimer's Therapy: Multitarget COX-2 Inhibitors with Anti-Amyloid β; Anti-Tau; Antioxidant; and Neuroprotective Activities
errRSC Med. Chem.
IF3.6
err2025-11-10
err0
PREAI
errMichael Emad; Reham Waheed; Zeinab Mostafa; Sarah S Darwish; Rosa Purgatorio; Daniela V Miniero; Annalisa De Palma; Tzu-Peng Cheng; Yu-Cheng Chen; Moustafa Gabr; Ahmed M El Kerdawy; Marco Catto; Ashraf H. Abadi; Tsong-Long Hwang; Mohammad Abdel-Halim
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Investigating Amphoteric 3,4′-Biscoumarin-Based ortho-[(Dialkylamino)methyl]phenols as Dual MAO and ChE Inhibitors
errInternational Journal of Molecular Sciences 2025, Vol. 26, Page 10197
IF0
err2025-10-20
err0
errOAAI
errAnthi Petrou; Caterina Deruvo; Rosa Purgatorio; Boris Lichitsky; Andrey N. Komogortsev; Victor G. Kartsev; Modesto de Candia; Marco Catto; Cosimo D. Altomare; Athina Geronikaki
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Revisiting COX-2 Inhibitors for Alzheimer's Disease as Multitargeted Ligands: Development of 4-Hydrazono-Pyrazolidinediones with Tuned COX Selectivity Profile and Improved Cellular Potency
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-10-13
err0
PREAI
errReham Waheed; Zeinab Moustafa; Michael Emad; Sarah S. Darwish; Rosa Purgatorio; Daniela Valeria Miniero; Annalisa De Palma; Tzu-Peng Cheng; Ting-Yu Wang; Yu-Cheng Chen; Ahmed M. El Kerdawy; Moustafa T. Gabr; Marco Catto; Ashraf H. Abadi; Tsong-Long Hwang; Mohammad Abdel-Halim
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The first-in-class 1,3,5-triazine-derived dual 5-HT6R/FAAH modulators in search for potential drug against neurodegenerative diseases with cognitive impairment
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-08-05
err0
errOAAI
errKinga Czarnota-Łydka; Katarzyna Kucwaj-Brysz; Barbara Mordyl; Monika Głuch-Lutwin; Tadeusz Karcz; Magdalena Jastrzębska-Więsek; Anna Partyka; Monika Dąbrowska; Grzegorz Satała; Sylwia Sudoł-Tałaj; Leonardo Brunetti; Modesto de Candia; Rosa Purgatorio; Marco Cerini; Luca Piemontese; Sabina Podlewska; Gniewomir Latacz; Małgorzata Starek; Anna Wesołowska; Antonio Carrieri; Jadwiga Handzlik
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Tunable Preparation of α-Aminoacyl Fluorides and α-Fluoroamides via Base-Induced Cascade Multiple-Cleavage Processes from Bromodifluorohydrin Reagents and Amines
errADVANCED SYNTHESIS & CATALYSIS
IF4
err2025-08-01
err0
errOAAI
errDe Santis, Giulia; Maranzana, Andrea; Lauria, Federica; Spennacchio, Mauro; Andresini, Michael; Purgatorio, Rosa; Colella, Marco; Luisi, Renzo; Degennaro, Leonardo
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Light-mediated activation/deactivation control and in vitro ADME-Tox profiling of a donepezil-like Dual AChE/MAO-B Inhibitor
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2025-06-01
err0
errOAAI
errPoggialini, Federica; Governa, Paolo; Vagaggini, Chiara; Maramai, Samuele; Lamponi, Stefania; Mugnaini, Claudia; Brizzi, Antonella; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Dreassi, Elena; Manetti, Fabrizio; Corelli, Federico; Altomare, Cosimo Damiano; Cappelli, Andrea; Paolino, Marco
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The potential of MAO inhibitors as chemotherapeutics in cancer: A literature survey
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-02-01
err0
errOAAI
errSblano, Sabina; Boccarelli, Angelina; Deruvo, Caterina; La Spada, Gabriella; de Candia, Modesto; Purgatorio, Rosa; Altomare, Cosimo Damiano; Catto, Marco
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Advances in synthesis of novel annulated azecines and their unique pharmacological properties
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-12-01
err0
PREAI
errListratova, Anna V.; Samarelli, Francesco; Titov, Alexander A.; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Varlamov, Alexey V.; Voskressensky, Leonid G.; Altomare, Cosimo D.
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errSave
Pleiotropic Effects of Direct Oral Anticoagulants in Chronic Heart Failure and Atrial Fibrillation: Machine Learning Analysis
errMOLECULES
IF4.6
err2024-06-04
err2
errOAAI
errMele, Marco; Mele, Antonietta; Imbrici, Paola; Samarelli, Francesco; Purgatorio, Rosa; Dinoi, Giorgia; Correale, Michele; Nicolotti, Orazio; De Luca, Annamaria; Brunetti, Natale Daniele; Liantonio, Antonella; Amoroso, Nicola
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Nature-Inspired 1-Phenylpyrrolo[2,1-a]isoquinoline Scaffold for Novel Antiproliferative Agents Circumventing P-Glycoprotein-Dependent Multidrug Resistance
errPHARMACEUTICALS
IF4.8
err2024-04-22
err2
errOAAI
errNevskaya, Alisa A.; Purgatorio, Rosa; Borisova, Tatiana N.; Varlamov, Alexey V.; Anikina, Lada V.; Obydennik, Arina Yu.; Nevskaya, Elena Yu.; Niso, Mauro; Colabufo, Nicola A.; Carrieri, Antonio; Catto, Marco; de Candia, Modesto; Voskressensky, Leonid G.; Altomare, Cosimo D.
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Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino [4,3-b]indol-1(2H)-one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-04-01
err6
errOAAI
errSamarelli, Francesco; Purgatorio, Rosa; Lopopolo, Gianfranco; Deruvo, Caterina; Catto, Marco; Andresini, Michael; Carrieri, Antonio; Nicolotti, Orazio; De Palma, Annalisa; Miniero, Daniela Valeria; de Candia, Modesto; Altomare, Cosimo D.
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A second life for MAO inhibitors? From CNS diseases to anticancer therapy
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-03-01
err6
errOAAI
errSblano, Sabina; Boccarelli, Angelina; Mesiti, Francesco; Purgatorio, Rosa; de Candia, Modesto; Catto, Marco; Altomare, Cosimo D.
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A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics
errANTIOXIDANTS
IF6.6
err2024-01-22
err5
errOAAI
errPurgatorio, Rosa; Boccarelli, Angelina; Pisani, Leonardo; de Candia, Modesto; Catto, Marco; Altomare, Cosimo D.
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Investigation on Novel E/Z 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity
errMOLECULES
IF4.6
err2023-08-03
err7
errOAAI
errPaolino, Marco; de Candia, Modesto; Purgatorio, Rosa; Catto, Marco; Saletti, Mario; Tondo, Anna Rita; Nicolotti, Orazio; Cappelli, Andrea; Brizzi, Antonella; Mugnaini, Claudia; Corelli, Federico; Altomare, Cosimo D.
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Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT6 receptor interaction
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2023-04-01
err6
errOAAI
errAsproni, Battistina; Catto, Marco; Loriga, Giovanni; Murineddu, Gabriele; Corona, Paola; Purgatorio, Rosa; Cichero, Elena; Fossa, Paola; Scarano, Naomi; Martinez, Anton L.; Brea, Jose; Pinna, Gerard A.
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Synthesis of Novel Benzo[b][1,6]naphthyridine Derivatives and Investigation of Their Potential as Scaffolds of MAO Inhibitors
errMOLECULES
IF4.6
err2023-02-09
err5
errOAAI
errKulikova, Larisa N.; Raesi, Ghulam Reza; Levickaya, Daria D.; Purgatorio, Rosa; Spada, Gabriella La; Catto, Marco; Altomare, Cosimo D.; Voskressensky, Leonid G.
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Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity
errMOLECULES
IF4.6
err2022-09-23
err7
errOAAI
errTitov, Alexander A.; Purgatorio, Rosa; Obydennik, Arina Y.; Listratova, Anna, V; Borisova, Tatiana N.; de Candia, Modesto; Catto, Marco; Altomare, Cosimo D.; Varlamov, Alexey V.; Voskressensky, Leonid G.
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errSave
Evaluation of Novel Guanidino-Containing Isonipecotamide Inhibitors of Blood Coagulation Factors against SARS-CoV-2 Virus Infection
errVIRUSES-BASEL
IF3.5
err2022-08-05
err5
errOAAI
errMaio, Flavio De; Rullo, Mariagrazia; de Candia, Modesto; Purgatorio, Rosa; Lopopolo, Gianfranco; Santarelli, Giulia; Palmieri, Valentina; Papi, Massimiliano; Elia, Gabriella; De Candia, Erica; Sanguinetti, Maurizio; Altomare, Cosimo Damiano
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Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases
errMOLECULES
IF4.6
err2022-07-02
err8
errOAAI
errPurgatorio, Rosa; Gambacorta, Nicola; Samarelli, Francesco; Lopopolo, Gianfranco; de Candia, Modesto; Catto, Marco; Nicolotti, Orazio; Altomare, Cosimo D.
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First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease
errMOLECULES
IF4.6
err2021-08-27
err12
errOAAI
errPurgatorio, Rosa; Gambacorta, Nicola; de Candia, Modesto; Catto, Marco; Rullo, Mariagrazia; Pisani, Leonardo; Nicolotti, Orazio; Altomare, Cosimo D.
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Research Directions

No research directions
Co-authors
Cooperation Journals
M
Maurizio Sanguinetti
H-index: 92 · Papers: 890
O
Ottavio Arancio
H-index: 84 · Papers: 332
G
Gabriella Elia
H-index: 58 · Papers: 196
T
Tsong‐Long Hwang
H-index: 58 · Papers: 711
A
Angelo Carotti
H-index: 50 · Papers: 365
View more