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L

Ludo Van Den Bosch

University of Leuven

82H-index
415Paper Count
3.4WCitation Count
Published Papers 162
Publication Date
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Early and Divergent Lipid Mediator Remodelling in Fast Versus Slow Skeletal Muscles of Female hSOD1G93A Mice
errJournal of Cachexia Sarcopenia and Muscle
IF9.1
err2026-08-05
err0
errOAAI
errSebastiaan Dalle; Kaat Vanderbeke; Thibaut Burg; Moniek Schouten; Wout Lauriks; Nicole Hersmus; Ludo Van Den Bosch; Katrien Koppo
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Using human 3D organoid models to gain mechanistic insight in motor neuron diseases
errNature Reviews Neuroscience
IF26.7
err2026-07-06
err0
PREAI
errBenedetta Frizzi; Adriana Margarida Barbosa Correia; Irene Faravelli; Ludo Van Den Bosch; Stefania Corti
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errSave
CREsted: modeling genomic and synthetic cell-type-specific enhancers across tissues and species
errNature Methods
IF32.1
err2026-04-02
err0
errOAAI
errNiklas Kempynck; Seppe De Winter; Casper H. Blaauw; Vasileios Konstantakos; Eren Can Ekşi; Sam Dieltiens; Darina Abaffyová; Valérie Bercier; Ibrahim I. Taskiran; Gert Hulselmans; Katina Spanier; Valerie Christiaens; Ludo Van Den Bosch; Lukas Mahieu; Stein Aerts
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errSave
Axonal Eif5a hypusination controls local translation and mitigates defects in FUS-ALS
errNature Neuroscience
IF20
err2025-12-22
err0
errOAAI
errDiana Piol; Bilal Khalil; Tessa Robberechts; Theo Killian; Maria Georgopoulou; Gabriele Partel; David Wouters; Nikolai Hecker; Paraskevi Tziortzouda; Yana Verresen; Nikky Corthout; Sam Kint; Katy Vandereyken; Philip Van Damme; Thierry Voet; Kristofer Davie; Suresh Poovathingal; Ludo Van Den Bosch; Stein Aerts; Alejandro Sifrim; Sandrine Da Cruz
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errSave
C9orf72 hexanucleotide repeat expansions impair microglial response in ALS
errNature Neuroscience
IF20
err2025-10-14
err0
errOAAI
errPegah Masrori; Baukje Bijnens; Laura Fumagalli; Kristofer Davie; Suresh Kumar Poovathingal; Tim Meese; Annet Storm; Nicole Hersmus; Raheem Fazal; Diede van den Biggelaar; Bob Asselbergh; Roxane Gruel; Johanna Van Den Daele; Heidi Denton; Paula Polanco Miquel; Simona Manzella; Winnok H. De Vos; Siddhartan Chandran; Ludo Van Den Bosch; Dietmar Rudolf Thal; Renzo Mancuso; Philip Van Damme
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Pharmacologic Inhibition of Glutamate Dehydrogenase 1 Improves Functional Recovery of Neuromuscular Junctions and Muscle Function in Duchenne Muscular Dystrophy
erramerican journal of pathology
IF0
err2025-06-02
err0
errOAAI
errAndreia Pereira-Nunes; Ummi Ammarah; Min Shang; Iris Charatsidou; Himal Sharma; Bruna Pereira Sorroche; Max Nobis; Thibaut Burg; Stijn Verschoren; Frédéric Relaix; Alessio Rotini; Ludo Van Den Bosch; Marcello Delfini; Emanuele Berardi; Massimiliano Mazzone
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errSave
Lipid metabolism alterations in peripheral neuropathies
errNeuron
IF15
err2025-04-30
err0
PREAI
errAlessio Silva; Robert Prior; Maurizio D’Antonio; Johannes V. Swinnen; Ludo Van Den Bosch
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errSave
Sporadic ALS hiPSC-derived motor neurons show axonal defects linked to altered axon guidance pathways
errNEUROBIOLOGY OF DISEASE
IF5.6
err2025-03-01
err0
errOAAI
errYe, Lisha; Dittlau, Katarina Stoklund; Sicart, Adria; Janky, Rekin''s; Van Damme, Philip; van den Bosch, Ludo
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errSave
Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo
errNATURE COMMUNICATIONS
IF15.7
err2025-01-08
err1
errOAAI
errKempthorne, Liam; Vaizoglu, Deniz; Cammack, Alexander J.; Carcole, Mireia; Roberts, Martha J.; Mikheenko, Alla; Fisher, Alessia; Suklai, Pacharaporn; Muralidharan, Bhavana; Kroll, Francois; Moens, Thomas G.; Yshii, Lidia; Verschoren, Stijn; Holbling, Benedikt V.; Moreira, Francisco C.; Katona, Eszter; Coneys, Rachel; de Oliveira, Paula; Zhang, Yong-Jie; Jansen, Karen; Daughrity, Lillian M.; Mcgown, Alexander; Ramesh, Tennore M.; van den Bosch, Ludo; Lignani, Gabriele; Rahim, Ahad A.; Coyne, Alyssa N.; Petrucelli, Leonard; Rihel, Jason
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errSave
C21ORF2 mutations point towards primary cilia dysfunction in amyotrophic lateral sclerosis
errBRAIN
IF11.7
err2024-12-20
err0
PREAI
errDe Decker, Mathias; Zelina, Pavol; Moens, Thomas G.; Beckers, Jimmy; Contardo, Matilde; Dittlau, Katarina Stoklund; Van Schoor, Evelien; Ronisz, Alicja; Eggermont, Kristel; Moisse, Matthieu; Chandran, Siddharthan; Veldink, Jan H.; Thal, Dietmar Rudolf; van den Bosch, Ludo; Pasterkamp, R. Jeroen; Van Damme, Philip
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errSave
A pathogenic mutation in the ALS/FTD gene VCP induces mitochondrial hypermetabolism by modulating the permeability transition pore
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2024-10-10
err0
errOAAI
errVanderhaeghe, Silke; Prerad, Jovan; Tharkeshwar, Arun Kumar; Goethals, Elien; Vints, Katlijn; Beckers, Jimmy; Scheveneels, Wendy; Debroux, Eveline; Princen, Katrien; Van Damme, Philip; Fivaz, Marc; Griffioen, Gerard; van den Bosch, Ludo
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errSave
Novel Far-Red Fluorescent 1,4-Dihydropyridines for L-Type Calcium Channel Imaging
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-10-10
err0
PREAI
errBorgarelli, Carlotta; Klingl, Yvonne E.; Escamilla-Ayala, Abril; Scarponi, Carlotta; La Rovere, Rita M. L.; Dittlau, Katarina Stoklund; Bultynck, Geert; Sampaolesi, Maurilio; Schoenberger, Matthias; Munck, Sebastian; Van Den Bosch, Ludo; De Borggraeve, Wim M.; Ismalaj, Ermal
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errSave
Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response
errCELL REPORTS
IF6.9
err2024-09-01
err1
errOAAI
errGermeys, Christine; Vandoorne, Tijs; Davie, Kristofer; Poovathingal, Suresh; Heeren, Kara; Vermeire, Wendy; Nami, Fatemeharefeh; Moisse, Matthieu; Quaegebeur, Annelies; Sierksma, Annerieke; Rue, Laura; Sicart, Adria; Eykens, Caroline; De Cock, Lenja; De Strooper, Bart; Carmeliet, Peter; Van Damme, Philip; De Bock, Katrien; van den Bosch, Ludo
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A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2024-08-28
err0
errOAAI
errAhuja, K.; Vandenabeele, M.; Nami, F.; Lefevere, E.; Van Hoecke, J.; Bergmans, S.; Claes, M.; Vervliet, T.; Neyrinck, K.; Burg, T.; De Herdt, D.; Bhaskar, P.; Zhu, Y.; Looser, Z. J.; Loncke, J.; Gsell, W.; Plaas, M.; Agostinis, P.; Swinnen, J. V.; van den Bosch, L.; Bultynck, G.; Saab, A. S.; Wolfs, E.; Chai, Y. C.; Himmelreich, U.; Verfaillie, C.; Moons, L.; De Groef, L.
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errSave
Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs (vol 147, 6, 2024)
errACTA NEUROPATHOLOGICA
IF9.3
err2024-06-13
err0
errOAAI
errZhu, Yingli; Burg, Thibaut; Neyrinck, Katrien; Vervliet, Tim; Nami, Fatemeharefeh; Vervoort, Ellen; Ahuja, Karan; Sassano, Maria Livia; Chai, Yoke Chin; Tharkeshwar, Arun Kumar; De Smedt, Jonathan; Hu, Haibo; Bultynck, Geert; Agostinis, Patrizia; Swinnen, Johannes V.; van den Bosch, Ludo; da Costa, Rodrigo Furtado Madeiro; Verfaillie, Catherine
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Advances and challenges in modeling inherited peripheral neuropathies using iPSCs
errEXPERIMENTAL AND MOLECULAR MEDICINE
IF12.9
err2024-06-03
err1
errOAAI
errVan Lent, Jonas; Prior, Robert; Siles, Gonzalo Perez; Cutrupi, Anthony N.; Kennerson, Marina L.; Vangansewinkel, Tim; Wolfs, Esther; Mukherjee-Clavin, Bipasha; Nevin, Zachary; Judge, Luke; Conklin, Bruce; Tyynismaa, Henna; Clark, Alex J.; Bennett, David L.; Van Den Bosch, Ludo; Saporta, Mario; Timmerman, Vincent
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errSave
PMP22 duplication dysregulates lipid homeostasis and plasma membrane organization in developing human Schwann cells
errBRAIN
IF11.7
err2024-05-14
err3
errOAAI
errPrior, Robert; Silva, Alessio; Vangansewinkel, Tim; Idkowiak, Jakub; Tharkeshwar, Arun Kumar; Hellings, Tom P.; Michailidou, Iliana; Vreijling, Jeroen; Loos, Maarten; Koopmans, Bastijn; Vlek, Nina; Agaser, Cedrick; Kuipers, Thomas B.; Michiels, Christine; Rossaert, Elisabeth; Verschoren, Stijn; Vermeire, Wendy; de Laat, Vincent; Dehairs, Jonas; Eggermont, Kristel; van den Biggelaar, Diede; Bademosi, Adekunle T.; Meunier, Frederic A.; Vandeven, Martin; Van Damme, Philip; Mei, Hailiang; Swinnen, Johannes, V; Lambrichts, Ivo; Baas, Frank; Fluiter, Kees; Wolfs, Esther; van den Bosch, Ludo
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errSave
FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease
errNATURE COMMUNICATIONS
IF15.7
err2024-03-09
err6
errOAAI
errKodavati, Manohar; Wang, Haibo; Guo, Wenting; Mitra, Joy; Hegde, Pavana M.; Provasek, Vincent; Rao, Vikas H. Maloji; Vedula, Indira; Zhang, Aijun; Mitra, Sankar; Tomkinson, Alan E.; Hamilton, Dale J.; van den Bosch, Ludo; Hegde, Muralidhar L.
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errSave
The sense of antisense therapies in ALS
errTrends in Molecular Medicine
IF13.8
err2024-03-01
err12
errOAAI
errVan Daele, Sien H.; Masrori, Pegah; Van Damme, Philip; Van Den Bosch, Ludo
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TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish
errFRONTIERS IN CELLULAR NEUROSCIENCE
IF4
err2024-02-21
err1
errOAAI
errVan Schoor, Evelien; Strubbe, Dufie; Braems, Elke; Weishaupt, Jochen; Ludolph, Albert C.; Van Damme, Philip; Thal, Dietmar Rudolf; Bercier, Valerie; Van den Bosch, Ludo
errShare
errSave

Research Directions

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Co-authors
Cooperation Journals
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Peter Carmeliet
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C
Cisca Wijmenga
H-index: 169 · Papers: 996
B
Benjamin M. Neale
H-index: 160 · Papers: 798
B
Bart De Strooper
H-index: 142 · Papers: 684
C
Christine Van Broeckhoven
H-index: 141 · Papers: 1.2K
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