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H

Hiten D. Madhani

Department of Biochemistry and Biophysics

51H-index
167Paper Count
1.4WCitation Count
Published Papers 61
Publication Date
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Mammalian-evolved strains of the fungal pathogen Cryptococcus neoformans show adaptation via heritable transcript level differences specific to mouse MHC haplotype
errBMC Genomics
IF3.7
err2026-07-21
err0
errOAAI
errCarter B. Ayers; Matthew J. Nalley; Hiten D. Madhani; Wayne K. Potts; Erin E. McClelland; Rebecca L. Seipelt-Thiemann
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Functional insight into cyclin-dependent kinase (CDK)7 via chemical inhibition of the priority fungal pathogen Cryptococcus neoformans
errMBIO
IF4.7
err2025-10-01
err0
PREAI
errSethiya, Pooja; Desmarini, Desmarini; Bowring, Bethany Grace; Cesar, Kyle; Boucher, Michael J.; Wei, Angela L.; Madhani, Hiten D.; Crossett, Ben; Connelly, Angela; Halliday, Catriona L.; Chen, Sharon C. -A.; Lai, Joey; Wong, Koon Ho; Djordjevic, Julianne Teresa
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errSave
CRISPR/Cas9-compatible plasmids enabling seven dominant genetic selection methods for the human fungal pathogen Cryptococcus neoformans
errMICROBIOLOGY SPECTRUM
IF3.8
err2025-09-01
err0
PREAI
errBoucher, Michael J.; Madhani, Hiten D.
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errSave
Phenotypic landscape of an invasive fungal pathogen reveals its unique biology
errCell
IF42.5
err2025-06-11
err0
PREAI
errMichael J. Boucher; Sanjita Banerjee; Meenakshi B. Joshi; Angela L. Wei; Matthew J. Nalley; Manning Y. Huang; Susan Lei; Massimiliano Ciranni; Andrew Condon; Andreas Langen; Thomas D. Goddard; Ippolito Caradonna; Alexi I. Goranov; Christina M. Homer; Yasaman Mortensen; Sarah Petnic; Morgann C. Reilly; Yi Xiong; Katherine J. Susa; Vito Paolo Pastore; Balyn W. Zaro; Hiten D. Madhani
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On-Resin Assembly of Macrocyclic Inhibitors of Cryptococcus neoformans May1: A Pathway to Potent Antifungal Agents
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-04-22
err0
errOAAI
errKrystufek, Robin; Verner, Vaclav; Sacha, Pavel; Hadzima, Martin; Trajhan, Filip; Starkova, Jana; Tloustova, Eva; Dvorakova, Alexandra; Pecina, Adam; Brynda, Jiri; Chalupsky, Karel; Hajek, Miroslav; Boucher, Michael J.; Majer, Pavel; Rezac, Jan; Madhani, Hiten D.; Craik, Charles S.; Konvalinka, Jan
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Understanding the dynamic design of the spliceosome
errTRENDS IN BIOCHEMICAL SCIENCES
IF11
err2024-07-01
err2
PREAI
errBeusch, Irene; Madhani, Hiten D.
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errSave
Convergent evolution of innate immune-modulating effectors in invasive fungal pathogens
errTRENDS IN MICROBIOLOGY
IF14.9
err2024-05-01
err3
PREAI
errBoucher, Michael J.; Madhani, Hiten D.
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errSave
Understanding the dynamic design of the human spliceosome
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errMadhani, Hiten
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errSave
Meet the authors: Irene Beusch and Hiten Madhani
errMOLECULAR CELL
IF16.6
err2023-07-01
err0
errOAAI
errBeusch, Irene; Madhani, Hiten
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errSave
Targeted high-throughput mutagenesis of the human spliceosome reveals its in vivo operating principles
errMOLECULAR CELL
IF16.6
err2023-07-01
err14
errOAAI
errBeusch, Irene; Rao, Beiduo; Studer, Michael K.; Luhovska, Tetiana; Sukyte, Viktorija; Lei, Susan; Oses-Prieto, Juan; SeGraves, Em; Burlingame, Alma; Jonas, Stefanie; Madhani, Hiten D.
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Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system
errIMMUNITY
IF26.3
err2023-07-01
err12
errOAAI
errDe Giovanni, Marco; Dang, Eric V.; Chen, Kevin Y.; An, Jinping; Madhani, Hiten D.; Cyster, Jason G.
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errSave
Intrinsic mesoscale properties of a Polycomb protein underpin heterochromatin fidelity
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2023-05-22
err3
PREAI
errLee, Sujin; Abini-Agbomson, Stephen; Perry, Daniela S.; Goodman, Allen; Rao, Beiduo; Huang, Manning Y.; Diedrich, Jolene K.; Moresco, James J.; Yates III, John R. R.; Armache, Karim-Jean; Madhani, Hiten D.
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Spt6 Is Required for Heterochromatic Silencing in the Fission Yeast Schizosaccharomyces pombe
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err40
errOAAI
errKiely, Christine M.; Marguerat, Samuel; Garcia, Jennifer F.; Madhani, Hiten D.; Baehler, Juerg; Winston, Fred
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errSave
Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance
errMOLECULAR CELL
IF16.6
err2022-03-01
err10
errOAAI
errWang, Juncheng; Catania, Sandra; Wang, Chongyuan; de la Cruz, M. Jason; Rao, Beiduo; Madhani, Hiten D.; Patel, Dinshaw J.
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errSave
Coupling of spliceosome complexity to intron diversity
errCURRENT BIOLOGY
IF7.5
err2021-11-01
err27
errOAAI
errSales-Lee, Jade; Perry, Daniela S.; Bowser, Bradley A.; Diedrich, Jolene K.; Rao, Beiduo; Beusch, Irene; Yates, John R.; Roy, Scott W.; Madhani, Hiten D.
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errSave
Short homology-directed repair using optimized Cas9 in the pathogen Cryptococcus neoformans enables rapid gene deletion and tagging
errGENETICS
IF5.1
err2021-10-23
err28
errOAAI
errHuang, Manning Y.; Joshi, Meenakshi B.; Boucher, Michael J.; Lee, Sujin; Loza, Liza C.; Gaylord, Elizabeth A.; Doering, Tamara L.; Madhani, Hiten D.
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errSave
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-05-18
err18
errOAAI
errKrystufek, Robin; Sacha, Pavel; Starkova, Jana; Brynda, Jiri; Hradilek, Martin; Tloust'ova, Eva; Grzymska, Justyna; Rut, Wioletta; Boucher, Michael J.; Drag, Marcin; Majer, Pavel; Hajek, Miroslav; Rezacova, Pavlina; Madhani, Hiten D.; Craik, Charles S.; Konvalinka, Jan
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Coordinate genomic association of transcription factors controlled by an imported quorum sensing peptide inCryptococcus neoformans
errPLOS GENETICS
IF3.7
err2020-09-21
err10
errOAAI
errSummers, Diana K.; Heitman, Joseph; Perry, Daniela S.; Rao, Beiduo; Madhani, Hiten D.
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ATP Hydrolysis by the SNF2 Domain of Dnmt5 Is Coupled to Both Specific Recognition and Modification of Hemimethylated DNA
errMOLECULAR CELL
IF16.6
err2020-07-01
err10
errOAAI
errDumesic, Phillip A.; Stoddard, Caitlin, I; Catania, Sandra; Narlikar, Geeta J.; Madhani, Hiten D.
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errSave
Cholesterol in quarantine
errNATURE IMMUNOLOGY
IF27.6
err2020-06-08
err6
PREAI
errDang, Eric V.; Madhani, Hiten D.; Vance, Russell E.
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Research Directions

No research directions
Co-authors
Cooperation Journals
E
Eric S. Lander
H-index: 271 · Papers: 897
J
John R. Yates
H-index: 188 · Papers: 1.5K
J
Jonathan S. Weissman
H-index: 157 · Papers: 550
G
Gerald R. Fink
H-index: 136 · Papers: 325
D
Dinshaw J. Patel
H-index: 135 · Papers: 837
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