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Candidate genes affecting stomatal density in rice (Oryza sativa L.) identified by genome-wide association Phetluan, Watchara; Wanchana, Samart; Aesomnuk, Wanchana; Adams, Julian; Pitaloka, Mutiara K.; Ruanjaichon, Vinitchan; Vanavichit, Apichart; Toojinda, Theerayut; Gray, Julie E.; Arikit, Siwaret Share Save
Targeting CDK9 for treatment of colorectal cancer Rahaman, Muhammed H.; Lam, Frankie; Zhong, Longjin; Teo, Theodosia; Adams, Julian; Yu, Mingfeng; Milne, Robert W.; Pepper, Chris; Lokman, Noor A.; Ricciardelli, Carmela; Oehler, Martin K.; Wang, Shudong Share Save
CDKI-73: an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia Rahaman, Muhammed H.; Yu, Yingyi; Zhong, Longjin; Adams, Julian; Lam, Frankie; Li, Peng; Noll, Ben; Milne, Robert; Peng, Jun; Wang, Shudong Share Save
US immigration order strikes against biotech Levin, Jeremy M.; Holtzman, Steven H.; Maraganore, John; Hastings, Paul J.; Cohen, Ron; Dahiyat, Bassil; Adams, Julian; Adams, Chris; Ahrens, Brett; Albers, Jeff; Aspinall, Mara G.; Audia, James E.; Babler, Martin; Barrett, Peter; Barry, Zoe; Bermingham, Nessan; Blocha, Stephen; Blum, Robert I.; Bolno, Paul B.; Bonney, Michael W.; Booth, Bruce; Bradbury, Daniel M.; Brauer, Steven K.; Byers, Brook; Cagnoni, Pablo J.; Cali, Brian M.; Ciechanover, Isaac; Clark, Chip; Clayman, Michael D.; Cleland, Jeff L.; Cobb, Paula; Cooper, Ron; Currie, Mark G.; Diekman, John; Dobmeier, Eric L.; Doerfler, Doug; Donley, Elizabeth L. R.; Dunsire, Deborah; During, Matthew; Eckstein, Jens W.; Elenko, Eric; Exter, Neil A.; Fleming, Jonathan J.; Flesher, Gregory J.; Formela, Jean-Francois; Forrester, Robert; Francois, Cedric; Franklin, Heather; Freemana, Mason W.; Furst, Howard; Gage, Leonard Patrick; Galakatos, Nicholas; Gallagher, Brian M.; Geraghty, James A.; Gill, Simba; Goeddel, David V.; Goldsmith, Mark A.; Gowen, Maxine; Goyal, Vikas; Graney, Tom; Grayzel, David; Greene, Barry; Grint, Paul; Gutierrez-Ramos, J. C.; Haney, Bill; Tuan Ha-Ngoc; Harris, Tim; Hasnain, Faheem; Hata, Yujiro Steve; Hecht, Peter; Henshaw, Leslie; Heyman, Rich; Hoppenot, Herve; Horvitz, H. Robert; Hughes, Thomas E.; Hutton, Wende S.; Isaacs, Stephen T.; Jenkins, Annalisa; Jonker, Jeff; Kaplan, Jeff; Karsen, Perry; Keiper, Jeb; Kim, Jean; Kindler, Jeff; King, Rachel; King, Vanessa; Kjellson, Nina; Koenig, Scott; Koenig, Gerhard; Kolchinsky, Peter; Laikind, Paul; Langer, Robert (Bob); Lee, John J.; Leff, Jonathan S.; Leicher, Bruce A.; Leschly, Nick; Levin, Andrew; Levin, Mark; Levine, Arnold J.; Levy, Alan; Liu, David R.; Lodish, Harvey F.; Lopatin, Uri; Love, Ted W.; Macdonald, Guy; Maderis, Gail J.; Mahadevia, Ankit; Mahanthappa, Nagesh K.; Martin, Joel F.; Martin, Alex; Martucci, W. Eddie; McArthur, James G.; McCann, Corey M.; McCarthy, Sean A.; McDonough, C. Geoffrey; Mendlein, John; Miller, Larry; Miralles, Diego; Moch, Kenneth I.; More, Bob; Myers, Andrew G.; Narachi, Michael A.; Nashat, Amir; Nelson, Wendy; Newell, William J.; Olle, Bernat; Osborn, John E.; Owens, Julia C.; Pande, Atul; Papadopoulos, Stelios; Parker, H. Stewart; Parmara, Kush M.; Patterson, Matthew R.; Paul, Steve M.; Perez, Rob; Perry, Matthew; Pfeffer, Cary G.; Powell, Mike; Pruzanski, Mark; Purcell, Dennis J.; Rakhit, Amit; Ramamoorthi, Kartik; Rastetter, William; Rawcliffe, Adrian (Ad); Reid, Laurence E.; Renaud, Ron C.; Rhodes, Jason P.; Rieflin, William J.; Robins, Chad; Rocklageb, Scott M.; Rosenblatt, Michael; Rosin, Jonathan G.; Rutter, William J.; Saha, Saurabh; Samuels, Camille; Sato, Vicki L.; Scangos, George; Scarlett, John A.; Schenkein, David; Schreiber, Stuart L.; Schwabb, Andrew; Sekhri, Paul; Shah, Rajeev; Shenk, Thomas; Siegall, Clay B.; Simon, Nick J.; Simonian, Nancy; Stein, Jeff; Su, Michael; Szela, Mary T.; Taglietti, Marco; Tandon, Nina; Termeer, Henri; Thornberry, Nancy A.; Tolar, Martin; Ulevitchc, Richard; Vaishnaw, Akshay K.; VanLent, Anne; Varsavsky, Martin; Vlasuk, George P.; Vounatsos, Michel; Waksal, Samuel G.; Warma, Neil; Watts, Ryan J.; Werber, Yaron; Westphal, Christoph; Wierenga, Wendell; Williams, Doug E.; Williams, Lewis (Rusty); Xanthopoulos, Kleanthis G.; Zohar, Daphne; Zweifach, Sandford (Sandy) Share Save
Development of a Multi Kilogram-Scale, Tandem Cyclopropanation Ring-Expansion Reaction en Route to Hedgehog Antagonist IPI-926 Austad, Brian C.; Hague, Andrew B.; White, Priscilla; Peluso, Stephane; Nair, Somarajan J.; Depew, Kristopher M.; Grogan, Michael J.; Charette, Andre B.; Yu, Lin-Chen; Lory, Caroline D.; Grenier, Louis; Lescarbeau, Andre; Lane, Benjamin S.; Lombardy, Richard; Behnke, Mark L.; Koney, Nii; Porter, James R.; Campbell, Matthew J.; Shaffer, Jeanne; Xiong, Jimin; Helble, Joseph C.; Foley, Michael A.; Adams, Julian; Castro, Alfredo C.; Tremblay, Martin R. Share Save
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Discovery of (E)-3-((Styrylsulfonyl)methyl)pyridine and (E)-2-((Styrylsulfonyl)methyl)pyridine Derivatives as Anticancer Agents: Synthesis, Structure-Activity Relationships, and Biological Activities Lu, Tiangong; Goh, Aik Wye; Yu, Mingfeng; Adams, Julian; Lam, Frankie; Teo, Theodosia; Li, Peng; Noll, Ben; Zhong, Longjin; Diab, Sarah; Chahrour, Osama; Hu, Anran; Abbas, Abdullahi Y.; Liu, Xiangrui; Huang, Shiliang; Sumby, Christopher J.; Milne, Robert; Midgley, Carol; Wang, Shudong Share Save
Hsp90 (Heat Shock Protein 90) Inhibitor Occupancy Is a Direct Determinant of Client Protein Degradation and Tumor Growth Arrest in Vivo Tillotson, Bonnie; Slocum, Kelly; Coco, John; Whitebread, Nigel; Thomas, Brian; West, Kip A.; MacDougall, John; Ge, Jie; Ali, Janid A.; Palombella, Vito J.; Normant, Emmanuel; Adams, Julian; Fritz, Christian C. Share Save
The antiproliferative activity of the heat shock protein 90 inhibitor IPI-504 is not dependent on NAD(P)H:quinone oxidoreductase 1 activity in vivo Douglas, Mark; Lim, Alice R.; Porter, James R.; West, Kip; Pink, Melissa M.; Ge, Jie; Wylie, Andrew A.; Tibbits, Thomas T.; Biggs, Kurtis; Curtis, Michael; Palombella, Vito J.; Adams, Julian; Fritz, Christian C.; Normant, Emmanuel Share Save
Discovery of a Potent and Orally Active Hedgehog Pathway Antagonist (IPI-926) Tremblay, Martin R.; Lescarbeau, Andre; Grogan, Michael J.; Tan, Eddy; Lin, Grace; Austad, Brian C.; Yu, Lin-Chen; Behnke, Mark L.; Nair, Somarajan J.; Hagel, Margit; White, Kerry; Conley, James; Manna, Joseph D.; Alvarez-Diez, Teresa M.; Hoyt, Jennifer; Woodward, Caroline N.; Sydor, Jens R.; Pink, Melissa; MacDougall, John; Campbell, Matthew J.; Cushing, Jill; Ferguson, Jeanne; Curtis, Michael S.; McGovern, Karen; Read, Margaret A.; Palombella, Vito J.; Adams, Julian; Castro, Alfredo C. Share Save
Semisynthetic Cyclopamine Analogues as Potent and Orally Bioavailable Hedgehog Pathway Antagonists Tremblay, Martin R.; Nevalainen, Marta; Nair, Sornarajan J.; Porter, Jarnes R.; Castro, Alfredo C.; Behnke, Mark L.; Yu, Lin-Chen; Hagel, Maroit; White, Kerry; Faia, Kerrie; Grenier, Louis; Campbell, Matthew J.; Cushing, Jill; Woodward, Caroline N.; Hoyt, Jennifer; Foley, Michael A.; Read, Margaret A.; Sydor, Jens R.; Tong, Jeffrey K.; Palombella, Vito J.; McGovern, Karen; Adams, Julian Share Save
Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90 Sydor, Jens R.; Normant, Emmanuel; Pien, Christine S.; Porter, James R.; Ge, Jie; Grenier, Louis; Pak, Roger H.; Ali, Janid A.; Dembski, Marlene S.; Hudak, Jebecka; Patterson, Jon; Penders, Courtney; Pink, Melissa; Read, Margaret A.; Sang, Jim; Woodward, Caroline; Zhang, Yilong; Grayzel, David S.; Wright, Jim; Barrett, John A.; Palombella, Vito J.; Adams, Julian; Tong, Jeffrey K. Share Save
Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90 Ge, Jie; Normant, Emmanuel; Porter, James R.; Ali, Janid A.; Dembski, Marlene S.; Gao, Yun; Georges, Asimina T.; Grenier, Louis; Pak, Roger H.; Patterson, Jon; Sydor, Jens R.; Tibbitts, Thomas T.; Tong, Jeffrey K.; Adams, Julian; Palombella, Vito J. Share Save
Inhibition of nuclear factor-κB and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma Van Waes, C; Chang, AA; Lebowitz, PF; Druzgal, CH; Chen, Z; Elsayed, YA; Sunwoo, JB; Rudy, SF; Morris, JC; Mitchell, JB; Camphausen, K; Gius, D; Adams, J; Sausville, EA; Conley, BA Share Save
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