Not logged inBelvarafenib Inhibits the Growth of RAS-Mutant Acute Myeloid Leukemia Cell Lines in Vitro and Drives Adaptive Resistance In Vivo
Levinson, Anya L.; Bland, Nicolas; Huang, Benjamin J.; Tjoa, Karensa; Angus, Steven P.; Liu, Yunlong; Gerosa, Luca; Dela Cruz, Darlene; Lasater, Elisabeth A.; Segal, Udi; Foster, Scott; Shannon, Kevin .png)
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SaveEmergence of MEK1 mutations in RAF or RAS-mutant solid tumors following treatment with a combination of selective type II RAF inhibitor belvarafenib and MEK inhibitor cobimetinibHilz, Stephanie; Chen, Marissa; Nowicka, Malgorzata; Chakravarthy, Harini; Moshref, Maryam; Gerosa, Luca; Eng-Wong, Jennifer; Chou, Cassie; Noh, Young S.; Hong, Yoon-hee; Yan, Yibing Share Save Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene inductionChen, Jia-Yun; Hug, Clemens; Reyes, Jose; Tian, Chengzhe; Gerosa, Luca; Frohlich, Fabian; Ponsioen, Bas; Snippert, Hugo J. G.; Spencer, Sabrina L.; Jambhekar, Ashwini; Sorger, Peter K.; Lahav, Galit Share Save Share Save Multiplexed and reproducible high content screening of live and fixed cells using Dye DropMills, Caitlin E.; Subramanian, Kartik; Hafner, Marc; Niepel, Mario; Gerosa, Luca; Chung, Mirra; Victor, Chiara; Gaudio, Benjamin; Yapp, Clarence; Nirmal, Ajit J.; Clark, Nicholas; Sorger, Peter K. Share Save Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapyNg, Thomas S. C.; Hu, Huiyu; Kronister, Stefan; Lee, Chanseo; Li, Ran; Gerosa, Luca; Stopka, Sylwia A.; Burgenske, Danielle M.; Khurana, Ishaan; Regan, Michael S.; Vallabhaneni, Sreeram; Putta, Niharika; Scott, Ella; Matvey, Dylan; Giobbie-Hurder, Anita; Kohler, Rainer H.; Sarkaria, Jann N.; Parangi, Sareh; Sorger, Peter K.; Agar, Nathalie Y. R.; Jacene, Heather A.; Sullivan, Ryan J.; Buchbinder, Elizabeth; Mikula, Hannes; Weissleder, Ralph; Miller, Miles A. Share Save Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma CellsGerosa, Luca; Chidley, Christopher; Frohlich, Fabian; Sanchez, Gabriela; Lim, Sang Kyun; Muhlich, Jeremy; Chen, Jia-Yun; Vallabhaneni, Sreeram; Baker, Gregory J.; Schapiro, Denis; Atanasova, Mariya, I; Chylek, Lily A.; Shi, Tujin; Yi, Lian; Nicora, Carrie D.; Claas, Allison; Ng, Thomas S. C.; Kohler, Rainer H.; Lauffenburger, Douglas A.; Weissleder, Ralph; Miller, Miles A.; Qian, Wei-Jun; Wiley, H. Steven; Sorger, Peter K. Share Save ERK pulses drive non-genetic resistance in drug-adapted BRAFV600E melanoma cellsGerosa, Luca; Chidley, Christopher; Froehlich, Fabian; Sanchez, Gabriela; Lim, Sang Kyun; Muhlich, Jeremy; Chen, Jia-Yun; Baker, Gregory J.; Schapiro, Denis; Shi, Tujin; Yi, Lian; Nicora, Carrie D.; Qian, Wei-Jun; Wiley, H. Steven; Sorger, Peter Share Save Share Save Share Save Share Save Share Save Share Save Share Save Share Save Share Save Share Save 
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