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张

张岩 (Yan Zhang)

Virginia Commonwealth University

35H-index
238Paper Count
4.8KCitation Count
Published Papers 105
Publication Date
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Structural Determinants of μ-Opioid Receptor Antagonism and Respiratory Liability in Phenylfentanyl Analogues
errACS Chemical Neuroscience
IF3.9
err2026-04-30
err0
errOAAI
errEnnian Li; Balaji S. Kale; Abeje A. Silte; Rui Lyu; Neha Upadhyay; Logan T. Neel; Ahmed Reda; Huiqun Wang; William L. Dewey; Piyusha P. Pagare; Yan Zhang
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Investigating the Landscape of C6-Azaindole Side Chain on the Epoxymorphinan Skeleton via the Nitrogen Walk Concept: A Strategy to Enhance Drug-Like Properties
errJournal of Medicinal Chemistry
IF6.8
err2026-01-22
err0
errOAAI
errLogan Neel; Hongguang Ma; Ahmed Reda; Mengchu Li; Rachael Flammia; Samuel Woodard; James C. Gillespie; Dana E. Selley; William L. Dewey; Piyusha P. Pagare; Yan Zhang
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errSave
Abandoning random biopsies after Barrett's eradication: a cost-prohibitive inefficiency
errGastrointestinal Endoscopy
IF7.5
err2025-11-11
err0
PREAI
errYunda Fang; Yan Zhang
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errSave
Design, Syntheses, and Pharmacological Evaluations of Core Ring Expanded Fentanyl Analogues as Potential Counteracting Agents Against Fentanyl Induced Respiratory Depression
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-11-01
err0
PREAI
errSilte, Abeje A.; Li, Ennian; Kale, Balaji S.; Neel, Logan; Upadhyay, Neha; Flammia, Rachael; Lyu, Rui; St Onge, Celsey M.; Reda, Ahmed; Woodard, Samuel; Gillespie, James C.; Kim, Daniel; Selley, Dana E.; Dewey, William L.; Pagare, Piyusha P.; Zhang, Yan
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An experimental study on the pollen particle blocking efficacy of a barrier nasal mask
errFrontiers in Medicine
IF3
err2025-10-16
err0
errOAAI
errYan Zhang†; Na Lu†; Yuxiang Zhao; Jinping Wang
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errSave
CDK11 Promotes Paclitaxel Resistance in Cervical Cancer by Regulating LATS1-Mediated Hippo Signaling Pathway Through Phosphorylation of NF2
errFASEB JOURNAL
IF4.2
err2025-10-11
err0
PREAI
errZhang, Yan; Lu, Jingyan; Qi, Minfang; Zhang, Xiaolu; Ou, Danmin
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errSave
Alpha-lipoic acid alleviates oxidative stress and brain damage in patients with sevoflurane anesthesia
errFRONTIERS IN PHARMACOLOGY
IF4.8
err2025-03-20
err0
errOAAI
errGao, Kailun; Wu, Ying; Zhang, Yan; Dang, Pei; Xue, Huanjia; Li, Teng; Zhou, Meiyan; Wang, Liwei; Zhu, Yangzi
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errSave
Exploring substitution effects on the potential dominant conformations of NBF derivatives leading to functional conversion at the mu opioid receptor
errRSC CHEMICAL BIOLOGY
IF3.1
err2025-01-01
err0
errOAAI
errLi, Ennian; Reda, Ahmed; Ma, Hongguang; Woodard, Samuel; Gillespie, James C.; Selley, Dana E.; Dewey, William L.; Pagare, Piyusha P.; Zhang, Yan
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errSave
Effects of derivatization and probiotic transformation on the antioxidative activity of fruit polyphenols
errFOOD CHEMISTRY-X
IF8.2
err2024-10-01
err1
errOAAI
errWang, Yixuan; Wang, Chenxi; Shi, Junling; Zhang, Yan
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errSave
Effects of Selective and Mixed-Action Kappa and Delta Opioid Receptor Agonists on Pain-Related Behavioral Depression in Mice
errMOLECULES
IF4.6
err2024-07-16
err1
errOAAI
errNegus, S. Stevens; Onge, Celsey M. St; Lee, Young K.; Li, Mengchu; Rice, Kenner C.; Zhang, Yan
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Win-win cooperation between plant substrates and probiotics: Revealing biotransformation and bioactive metabolites in Elaeagnus moorcroftii Wall. ex Schlecht fermented by Lacticaseibacillus paracasei YL-29
errLWT-FOOD SCIENCE AND TECHNOLOGY
IF6.6
err2024-07-01
err2
errOAAI
errWang, Chenxi; Wang, Yixuan; Teng, Yingdi; Zhang, Yan
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errSave
Systematic Structure-Activity Relationship Study of Nalfurafine Analogues toward Development of Potentially Nonaddictive Pain Management Treatments
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-05-30
err1
errOAAI
errSt. Onge, Celsey M.; Pagare, Piyusha P.; Zheng, Yi; Arriaga, Michelle; Stevens, David L.; Mendez, Rolando E.; Poklis, Justin L.; Halquist, Matthew S.; Selley, Dana E.; Dewey, William L.; Banks, Matthew L.; Zhang, Yan
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errSave
NCP, a Dual Kappa and Mu Opioid Receptor Agonist, Is a Potent Analgesic Against Inflammatory Pain without Reinforcing or Aversive Properties
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2024-04-01
err3
errOAAI
errHuang, Peng; Ho, Conrad K.; Cao, Danni; Inan, Saadet; Rawls, Scott M.; Li, Mengchu; Huang, Boshi; Pagare, Piyusha P.; Townsend, E. Andrew; Poklis, Justin L.; Halquist, Matthew S.; Banks, Matthew; Zhang, Yan; Liu-Chen, Lee-Yuan
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Investigation of volatile compounds during fermentation of Elaeagnus moorcroftii Wall.ex schlecht. juice by Bifidobacterium animalis subsp. lactis HN-3 and Lacticaseibacillus paracasei YL-29
errFOOD CHEMISTRY-X
IF8.2
err2024-03-01
err0
errOAAI
errWang, Yixuan; Li, Wenhao; Wang, Xiaojun; Hu, Qi; Kong, Junkai; Wang, Xiu; Lan, Zhenghui; Wang, Chenxi; Zhang, Yan
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errSave
Novel PROTAC probes targeting KDM3 degradation to eliminate colorectal cancer stem cells through inhibition of Wnt/β-catenin signaling
errRSC MEDICINAL CHEMISTRY
IF3.6
err2024-01-01
err0
errOAAI
errZaman, Shadid U.; Pagare, Piyusha P.; Ma, Hongguang; Hoyle, Rosalie G.; Zhang, Yan; Li, Jiong
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errSave
METTL3-mediated m6A RNA methylation was involved in aluminum-induced neurotoxicity
errECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
IF6.1
err2024-01-01
err2
errOAAI
errYang, Lingling; Chen, Liping; Li, Wenxue; Zhang, Yan; Yang, Guangyu; Huang, Bing; Cen, Yufang; Wang, Huiqi; Yang, Xueqin; Lin, Fangqin; Pang, Yaqin; Qi, Guangzi
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Molecular Pharmacology Profiling of Phenylfentanil and Its Analogues to Understand the Putative Involvement of an Adrenergic Mechanism in Fentanyl-Induced Respiratory Depression
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-12-29
err0
PREAI
errLi, Mengchu; Pagare, Piyusha P.; Ma, Hongguang; St Onge, Celsey M.; Mendez, Rolando E.; Gillespie, James C.; Stevens, David L.; Dewey, William L.; Selley, Dana E.; Zhang, Yan
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errSave
A cutting-edge strategy for spinal cord injury treatment: resident cellular transdifferentiation
errFRONTIERS IN CELLULAR NEUROSCIENCE
IF4
err2023-08-30
err0
errOAAI
errFang, Yu-Ming; Chen, Wei-Can; Zheng, Wan-Jing; Yang, Yu-Shen; Zhang, Yan; Chen, Xin-Li; Pei, Meng-Qin; Lin, Shu; He, He-Fan
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Quantitative assessment of the in-vitro binding kinetics of antisickling aromatic aldehydes with hemoglobin A: A universal HPLC-UV/Vis method to quantitate Schiff-base adduct formation
errJOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
IF3.1
err2023-01-01
err1
errOAAI
errXu, Xiaomeng; Ghatge, Mohini S.; Huang, Boshi; Alghamdi, Ahmed; Wang, Huiqun; Pierce, Daniel; Abdulmalik, Osheiza; Zhang, Yan; Safo, Martin K.; Venitz, Juergen
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Structural Alterations of the Address Moiety of NAN Leading to the Discovery of a Novel Opioid Receptor Modulator with Reduced hERG Toxicity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-12-20
err8
errOAAI
errMa, Hongguang; Pagare, Piyusha P.; Li, Mengchu; Neel, Logan T.; Mendez, Rolando E.; Gillespie, James C.; Stevens, David L.; Dewey, William L.; Selley, Dana E.; Zhang, Yan
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errSave

Research Directions

G蛋白偶联受体和信号转导研究基于受体和信号转导的天然产物药物筛选免疫抗炎活性天然产物的发现及机制研究
Co-authors
Cooperation Journals
I
Ian A. Wilson
H-index: 179 · Papers: 1.7K
D
Dale L. Boger
H-index: 102 · Papers: 1.1K
S
Stephen J. Benkovic
H-index: 92 · Papers: 565
张峰 cover
张峰 (Feng Zhang)
H-index: 91 · Papers: 1.1K
王
王志伟 (Zhiwei Wang)
H-index: 89 · Papers: 988
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