Not logged in Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers Chatterjee, Nilanjana; Pazarentzos, Evangelos; Mayekar, Manasi K.; Gui, Philippe; Allegakoen, David V.; Hrustanovic, Gorjan; Olivas, Victor; Lin, Luping; Verschueren, Erik; Johnson, Jeffrey R.; Hofree, Matan; Yan, Jenny J.; Newton, Billy W.; Dollen, John V.; Earnshaw, Charles H.; Flanagan, Jennifer; Chan, Elton; Asthana, Saurabh; Ideker, Trey; Wu, Wei; Suzuki, Junji; Barad, Benjamin A.; Kirichok, Yuriy; Fraser, James S.; Weiss, William A.; Krogan, Nevan J.; Tulpule, Asmin; Sabnis, Amit J.; Bivona, Trever G. Share Save
Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution Jonsson, Vanessa D.; Blakely, Collin M.; Lin, Luping; Asthana, Saurabh; Matni, Nikolai; Olivas, Victor; Pazarentzos, Evangelos; Gubens, Matthew A.; Bastian, Boris C.; Taylor, Barry S.; Doyle, John C.; Bivona, Trever G. Share Save
RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer Hrustanovic, Gorjan; Olivas, Victor; Pazarentzos, Evangelos; Tulpule, Asmin; Asthana, Saurabh; Blakely, Collin M.; Okimoto, Ross A.; Lin, Luping; Neel, Dana S.; Sabnis, Amit; Flanagan, Jennifer; Chan, Elton; Varella-Garcia, Marileila; Aisner, Dara L.; Vaishnavi, Aria; Ou, Sai-Hong I.; Collisson, Eric A.; Ichihara, Eiki; Mack, Philip C.; Lovly, Christine M.; Karachaliou, Niki; Rosell, Rafael; Riess, Jonathan W.; Doebele, Robert C.; Bivona, Trever G. Share Save
The Hippo effector YAP promotes resistance to RAF and MEK targeted therapies Lin, Luping; Sabnis, Amit; Chan, Elton; Olivas, Victor; Cade, Lindsay; Pazarentzos, Evangelos; Asthana, Saurabh; Neel, Dana; Yan, Jenny Jiacheng; Lu, Xinyuan; Pham, Luu; Wang, Mingxue; Karachaliou, Niki; Cao, Maria G.; Manzano, Jose L.; Ramirez, Jose L.; Torres, Jose M.; Buttitta, Fiamma; Rudin, Charles M.; Collisson, Eric A.; Algazi, Alain; Robinson, Eric; Osman, Iman; Munoz-Couselo, Eva; Cortes, Javier; Frederick, Dennie T.; Cooper, Zachary A.; McMahon, Martin; Marchetti, Antonio; Rosell, Rafael; Flaherty, Keith T.; Wargo, Jennifer A.; Bivona, Trever G. Share Save
Oncogenic activation of the PI3-kinase p110β isoform via the tumor-derived PIK3CβD1067V kinase domain mutation Pazarentzos, E.; Giannikopoulos, P.; Hrustanovic, G.; St John, J.; Olivas, V. R.; Gubens, M. A.; Balassanian, R.; Weissman, J.; Polkinghorn, W.; Bivona, T. G. Share Save
NF-κB-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer Blakely, Collin M.; Pazarentzos, Evangelos; Olivas, Victor; Asthana, Saurabh; Yan, Jenny Jiacheng; Tan, Irena; Hrustanovic, Gorjan; Chan, Elton; Lin, Luping; Neel, Dana S.; Newton, William; Bobb, Kathryn L.; Fouts, Timothy R.; Meshulam, Jeffrey; Gubens, Matthew A.; Jablons, David M.; Johnson, Jeffrey R.; Bandyopadhyay, Sourav; Krogan, Nevan J.; Bivona, Trever G. Share Save
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The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies Lin, Luping; Sabnis, Amit J.; Chan, Elton; Olivas, Victor; Cade, Lindsay; Pazarentzos, Evangelos; Asthana, Saurabh; Neel, Dana; Yan, Jenny Jiacheng; Lu, Xinyuan; Pham, Luu; Wang, Mingxue M.; Karachaliou, Niki; Gonzalez Cao, Maria; Luis Manzano, Jose; Luis Ramirez, Jose; Sanchez Torres, Jose Miguel; Buttitta, Fiamma; Rudin, Charles M.; Collisson, Eric A.; Algazi, Alain; Robinson, Eric; Osman, Iman; Munoz-Couselo, Eva; Cortes, Javier; Frederick, Dennie T.; Cooper, Zachary A.; McMahon, Martin; Marchetti, Antonio; Rosell, Rafael; Flaherty, Keith T.; Wargo, Jennifer A.; Bivona, Trever G. Share Save
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IκBα inhibits apoptosis at the outer mitochondrial membrane independently of NF-κB retention Pazarentzos, Evangelos; Mahul-Mellier, Anne-Laure; Datler, Christoph; Chaisaklert, Wanwisa; Hwang, Ming-Shih; Kroon, Jan; Qize, Ding; Osborne, Foy; Al-Rubaish, Abdullah; Al-Ali, Amein; Mazarakis, Nicholas D.; Aboagye, Eric O.; Grimm, Stefan Share Save
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The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis AbuAli, G.; Chaisaklert, W.; Stelloo, E.; Pazarentzos, E.; Hwang, M-S; Qize, D.; Harding, S. V.; Al-Rubaish, A.; Alzahrani, Aj; Al-Ali, A.; Sanders, T. A. B.; Aboagye, E. O.; Grimm, S. Share Save
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Dose-dependent Neuroprotection of VEGF165 in Huntington's Disease Striatum Ellison, Stuart M.; Trabalza, Antonio; Tisato, Veronica; Pazarentzos, Evangelos; Lee, Shirley; Papadaki, Vasiliki; Goniotaki, Despoina; Morgan, Sarah; Mirzaei, Nazanin; Mazarakis, Nicholas D. Share Save
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