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Thomas R. Ioerger

I Shou University
H-index:60
Citation Count:1.8万
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Evaluating selection at intermediate scales within genes provides robust identification of genes under positive selection in M. tuberculosis clinical isolates

评估基因内中等尺度上的选择作用，为识别在结核分枝杆菌临床分离株中受到正向选择的基因提供了稳健的方法。

Tuberculosis
IF2.9
2025-09-110
OA
Thomas R. Ioerger; Anthony Shatby
Genomic and Phenotypic Insights Into Antibiotic Resistance and Virulence of Klebsiella pneumoniae From the Environment in Southern Taiwan

来自中国台湾南部环境中克雷伯氏肺炎杆菌的抗生素耐药性和毒力的基因组与表型见解

JOURNAL OF INFECTIOUS DISEASES
IF4.5
2025-08-010
OAAI
Liao, Chun-Hsing; Huang, Ya-Ling; Ioerger, Thomas; Lim, Ke San; Huang, Yu-Chieh; Huang, Chen-Hsiu; Hsu, Chun-Ru
SuFEx-based antitubercular compound irreversibly inhibits Pks13

基于SuFEx的抗结核化合物不可逆地抑制Pks13

Nature
IF48.5
2025-07-300
PRE
Inna V. Krieger; Paridhi Sukheja; Baiyuan Yang; Su Tang; Daniel Selle; Ashley Woods; Curtis Engelhart; Pradeep Kumar; Michael B. Harbut; Dongdong Liu; Brendan Tsuda; Bo Qin; Grant A. L. Bare; Gencheng Li; Victor Chi; Julian Gambacurta; Janine Hvizdos; Matthew Reagan; Isabelle L. Jones; Lisa M. Massoudi; Lisa K. Woolhiser; Alessandro Cascioferro; Erica Kundrick; Parul Singh; William Reiley; Thomas R. Ioerger; Dilipkumar Reddy Kandula; Jacob W. McCabe; Taijie Guo; David Alland; Helena I. Boshoff; Dirk Schnappinger; Gregory T. Robertson; Khisi Mdluli; Kyoung-Jin Lee; Jiajia Dong; Shuangwei Li; Peter G. Schultz; Sean B. Joseph; Melissa S. Love; K. Barry Sharpless; H. Michael Petrassi; Arnab K. Chatterjee; James C. Sacchettini; Case W. McNamara
The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB): A Large-Scale Guide to Genetic Conditional Essentiality

结核分枝杆菌转座子测序数据库 (MtbTnDB)：遗传条件必需性的大规模指南

Molecular Microbiology
IF2.6
2025-06-170
OAAI
Adrian Jinich; Anisha Zaveri; Michael A. DeJesus; Amanda Spencer; Ricardo Almada-Monter; Emanuel Flores-Bautista; Clare M. Smith; Christopher M. Sassetti; Jeremy M. Rock; Sabine Ehrt; Dirk Schnappinger; Thomas R. Ioerger; Kyu Y. Rhee
TnSeq identifies genetic requirements of Mycobacterium tuberculosis for survival under vaccine-induced immunity

TnSeq鉴定了分枝杆菌 *Mycobacterium tuberculosis* 在疫苗诱导的免疫条件下的生存遗传需求

NPJ VACCINES
IF6.5
2025-05-220
OA
James, Kimra S.; Jain, Neharika; Witzl, Kelly; Cicchetti, Nico; Fortune, Sarah M.; Ioerger, Thomas R.; Martinot, Amanda J.; Carey, Allison F.
Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis

鉴定一类含有五氟苯基结构单元的化合物，该化合物靶向Pks13以抑制结核分枝杆菌的生长。

ACS INFECTIOUS DISEASES
IF3.8
2025-02-270
OA
Green, SR; Harrison, JR; Thompson, S; Murugesan, D; Libardo, MDJ; Engelhart, CA; Meshanni, J; Fletcher, D; Scullion, P; Edwards, D; Epemolu, O; Mutter, N; Shishikura, Y; Riley, J; Ioerger, TR; Guillén, JJR; López, LG; Read, KD; Barry, CE III; Schnappinger, D; Wyatt, PG; Boshoff, HIM; Cleghorn, LAT
Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains
MBIO
IF4.7
2025-02-050
PRE
Akusobi, Chidiebere; Choudhery, Sanjeevani; Benghomari, Bouchra S.; Wolf, Ian D.; Singhvi, Shreya; Ioerger, Thomas R.; Rubin, Eric J.
Frequently arising ESX-1-associated phase variants influence Mycobacterium tuberculosis fitness in the presence of host and antibiotic pressures
MBIO
IF4.7
2025-01-280
OAAI
Luna, Michael J.; Oluoch, Peter O.; Miao, Jiazheng; Culviner, Peter; Papavinasasundaram, Kadamba; Jaecklein, Eleni; Shell, Scarlet S.; Ioerger, Thomas R.; Fortune, Sarah M.; Farhat, Maha R.; Sassetti, Christopher M.
The anti-tubercular callyaerins target the Mycobacterium tuberculosis-specific non-essential membrane protein Rv2113
CELL CHEMICAL BIOLOGY
IF7.2
2024-10-010
OAAI
Podlesainski, David; Adeniyi, Emmanuel T.; Groener, Yvonne; Schulz, Florian; Krisilia, Violetta; Rehberg, Nidja; Richter, Tim; Sehr, Daria; Xie, Huzhuyue; Simons, Viktor E.; Kiffe-Delf, Anna-Lene; Kaschani, Farnusch; Ioerger, Thomas R.; Kaiser, Markus; Kalscheuer, Rainer
Mycobacterial RNase E cleaves with a distinct sequence preference and controls the degradation rates of most Mycolicibacterium smegmatis mRNAs
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2023-11-013
OAAI
Zhou, Ying; Sun, Huaming; Rapiejko, Abigail R.; Vargas-Blanco, Diego A.; Martini, Maria Carla; Chase, Michael R.; Joubran, Samantha R.; Davis, Alexa B.; Dainis, Joseph P.; Kelly, Jessica M.; Ioerger, Thomas R.; Roberts, Louis A.; Fortune, Sarah M.; Shell, Scarlet S.
Functional Whole Genome Screen of Nutrient-Starved Mycobacterium tuberculosis Identifies Genes Involved in Rifampin Tolerance
MICROORGANISMS
IF4.2
2023-09-090
OAAI
Matern, William M.; Harris, Harley T.; Danchik, Carina; McDonald, Marissa; Patel, Gopi; Srivastava, Aashish; Ioerger, Thomas R.; Bader, Joel S.; Karakousis, Petros C.
The Rip1 intramembrane protease contributes to iron and zinc homeostasis in Mycobacterium tuberculosis
MSPHERE
IF3.1
2023-08-242
OAAI
Nelson, Samantha J. J.; Williams, John T. T.; Buglino, John A. A.; Nambi, Subhalaxmi; Lojek, Lisa J. J.; Glickman, Michael S. S.; Ioerger, Thomas R. R.; Sassetti, Christopher M. M.
Synthesis and Structure-Activity Relationships of a New Class of Oxadiazoles Targeting DprE1 as Antitubercular Agents

靶向DprE1的新型恶二唑类抗结核药的合成和构效关系

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2023-08-152
OAAI
Yadav, Veena D. D.; Boshoff, Helena I. I.; Trifonov, Lena; Roma, Jose Santinni O.; Ioerger, Thomas R. R.; Barry, Clifton E. E.; Oh, Sangmi
Phase variation as a major mechanism of adaptation in Mycobacterium tuberculosis complex
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-07-039
OAAI
Vargas Jr, Roger; Luna, Michael J.; Freschi, Luca; Marin, Maximillian; Froom, Ruby; Murphy, Kenan C.; Campbell, Elizabeth A.; Ioerger, Thomas R.; Sassetti, Christopher M.; Farhat, Maha Reda
A mutant fitness assay identifies bacterial interactions in a model ocean hot spot

突变体适应性测定可识别模型海洋热点中的细菌相互作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-03-154
OAAI
Schreier, Jeremy E.; Smith, Christa B.; Ioerger, Thomas R.; Moran, Mary Ann
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2023-01-055
OAAI
Koller, Timm O.; Scheid, Ullrich; Koesel, Teresa; Herrmann, Jennifer; Krug, Daniel; Boshoff, Helena I. M.; Beckert, Bertrand; Evans, Joanna C.; Schlemmer, Jan; Sloan, Becky; Weiner, Danielle M.; Via, Laura E.; Moosa, Atica; Ioerger, Thomas R.; Graf, Michael; Zinshteyn, Boris; Abdelshahid, Maha; Nguyen, Fabian; Arenz, Stefan; Gille, Franziska; Siebke, Maik; Seedorf, Tim; Plettenburg, Oliver; Green, Rachel; Warnke, Anna-Luisa; Ullrich, Joachim; Warrass, Ralf; Barry, Clifton E., III; Warner, Digby F.; Mizrahi, Valerie; Kirschning, Andreas; Wilson, Daniel N.; Mueller, Rolf
1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis

1，3-二芳基吡唑基酰基磺酰胺靶向结核分枝杆菌中的HadAB/BC复合物

ACS INFECTIOUS DISEASES
IF3.8
2022-11-034
OAAI
Singh, Vinayak; Grzegorzewicz, Anna E.; Fienberg, Stephen; Muller, Rudolf; Khonde, Lutete Peguy; Sanz, Olalla; Alfonso, Salvatore; Urones, Beatriz; Drewes, Gerard; Bantscheff, Marcus; Ghidelli-Disse, Sonja; Ioerger, Thomas R.; Angala, Bhanupriya; Liu, Jiuyu; Lee, Richard E.; Sacchettini, James C.; Krieger, Inna, V; Jackson, Mary; Chibale, Kelly; Ghorpade, Sandeep R.
Deletion of Rv2571c Confers Resistance to Arylamide Compounds in Mycobacterium tuberculosis (65, e02334, 2021)
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2022-08-160
OA
Shelton, Catherine D.; McNeil, Matthew B.; Early, Julie V.; Ioerger, Thomas R.; Parish, Tanya
Transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding protein involved in septal peptidoglycan synthesis and antibiotic sensitivity
ELIFE
IF0
2022-06-0616
OA
Akusobi, Chidiebere; Benghomari, Bouchra S.; Zhu, Junhao; Wolf, Ian D.; Singhvi, Shreya; Dulberger, Charles L.; Ioerger, Thomas R.; Rubin, Eric J.; Kana, Bavesh D.
Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-04-0521
OAAI
Koh, Eun-Ik; Oluoch, Peter O.; Ruecker, Nadine; Proulx, Megan K.; Soni, Vijay; Murphy, Kenan C.; Papavinasasundaram, Kadamba; Reames, Charlotte J.; Trujillo, Carolina; Zaveri, Anisha; Zimmerman, Matthew D.; Aslebagh, Roshanak; Baker, Richard E.; Shaffer, Scott A.; Guinn, Kristine M.; Fitzgerald, Michael; Dartois, Veronique; Ehrt, Sabine; Hung, Deborah T.; Ioerger, Thomas R.; Rubin, Eric J.; Rhee, Kyu Y.; Schnappinger, Dirk; Sassetti, Christopher M.

Research Directions

The data has not been retrieved yet.
J
James C. Sacchettini
H-index:94Papers:384Citations:3.0万
E
Eric J. Rubin
H-index:90Papers:850Citations:2.9万
C
Christopher M. Sassetti
H-index:62Papers:191Citations:1.9万
S
Sarah M. Fortune
H-index:62Papers:247Citations:2.0万
R
Rainer Kalscheuer
H-index:42Papers:144Citations:7,438
H
Helena I. Boshoff
H-index:65Papers:266Citations:1.5万
C
Clifton E. Barry
H-index:113Papers:449Citations:5.0万
K
Kyu Y. Rhee
H-index:55Papers:197Citations:9,194
S
Sabine Ehrt
H-index:65Papers:169Citations:1.5万
T
Tanya Parish
H-index:56Papers:271Citations:1.1万