Gyanu Lamichhane - Publications, H-index & Citations

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Gyanu Lamichhane

johns hopkins university

41H-index

144Paper Count

5.1KCitation Count

Published Papers 58

Publication Date

Chemoproteomic Elucidation of β-Lactam Drug Targets in Mycobacterium abscessus

ACS Infectious Diseases

IF3.8

2026-04-17

OAAI

Kaylyn L. Devlin; Emily Hutchinson; Damon T. Leach; Leo J. Gorham; William C. Nelson; Gyanu Lamichhane; Vivian S. Lin; Kimberly E. Beatty

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Efficacies of Sequenced Monotherapies of Mycobacterium avium Lung Infection in Mouse

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2026-01-01

OAAI

Howe, Ruth A.; Rimal, Binayak; Khandelwal, Jay; Panthi, Chandra M.; Lamichhane, Gyanu

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Synthesis and evaluation of novel oxanthrene scaffold-derived oxazolidinone antibiotics with potent antitubercular activity and low cellular toxicity

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

IF2.2

2025-12-01

OAAI

Latterell, Kelsey R.; Keil, Evan; Kraemer, Benjamin R.; Huisken, Joe B.; Thomas, Ben A.; Daniels, Noah; Kaushik, Amit; Olson, Maria Lillian; Noriega, Pamela Melendez; Daniels, Maria Alejandra Pizarro; Janzen, Daron E.; Lamichhane, Gyanu; Campo, Monica; Ippoliti, J. Thomas

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Synthesis and antibacterial activity of novel benzodioxin-containing oxazolidinones against M. abscessus

Bioorganic & Medicinal Chemistry Letters

IF2.2

2025-08-06

PREAI

Connor M. Winkelhake; Binayak Rimal; Ben A. Thomas; Joe B. Huisken; Gyanu Lamichhane; J. Thomas Ippoliti

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A Phase 2a Study of the Early Bactericidal Activity of Rifampicin in Combination With Meropenem Plus Amoxicillin/Clavulanate Among Adults With Rifampicin-Resistant Pulmonary Tuberculosis

CLINICAL INFECTIOUS DISEASES

IF7.3

2025-06-01

OAAI

de Jager, Veronique; Mockeliunas, Laurynas; You, Huifang; Simonsson, Ulrika S. H.; Collings, Tarryn; Upton, Caryn M.; Bezuidenhout, Johannes A.; Gupte, Nikhil; Dorman, Susan E.; Nuermberger, Eric; Lamichhane, Gyanu; Diacon, Andreas H.; Dooley, Kelly E.

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The efficacy of a regimen comprising clarithromycin, clofazimine, and bedaquiline in a mouse model of chronic Mycobacterium avium lung infection

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2025-03-01

OAAI

Rimal, Binayak; Howe, Ruth A.; Panthi, Chandra; Lamichhane, Gyanu

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Oral oxaborole MRX-5 exhibits efficacy against pulmonary Mycobacterium abscessus in mouse

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2024-11-06

OAAI

Rimal, Binayak; Howe, Ruth A.; Panthi, Chandra M.; Wang, Wen; Lamichhane, Gyanu

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Efficacy of epetraborole against Mycobacteroides abscessus in a mouse model of lung infection

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2024-08-07

OAAI

Rimal, Binayak; Lippincott, Christopher K.; Panthi, Chandra M.; Xie, Yi; Keepers, Tiffany R.; Alley, M. R. K.; Lamichhane, Gyanu

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Efficacies of omadacycline plus amikacin plus imipenem and an all-oral regimen omadacycline plus clofazimine plus linezolid in a mouse model of M. abscessus lung disease

MSPHERE

IF3.1

2024-07-30

OAAI

Ignatius, Elisa H.; Rimal, Binayak; Panthi, Chandra M.; Belz, Daniel C.; Lippincott, Christopher K.; Deck, Daniel H.; Serio, Alisa W.; Lamichhane, Gyanu

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Case Commentary: Dual β-lactam as part of regimen to treat Mycobacterium abscessus lung disease

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2024-07-09

PREAI

Lippincott, Christopher K.; Lamichhane, Gyanu

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Efficacy of Omadacycline-Containing Regimen in a Mouse Model of Pulmonary Mycobacteroides abscessus Disease

MSPHERE

IF3.1

2023-04-20

OAAI

Rimal, Binayak; Nicklas, Danielle A.; Panthi, Chandra M.; Lippincott, Christopher K.; Belz, Daniel C.; Ignatius, Elisa H.; Deck, Daniel H.; Serio, Alisa W.; Lamichhane, Gyanu

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Structure-Activity Relationship of Penem Antibiotic Side Chains Used against Mycobacteria Reveals Highly Active Compounds

ACS INFECTIOUS DISEASES

IF3.8

2022-08-02

OAAI

Batchelder, Hunter R.; Zandi, Trevor A.; Kaushik, Amit; Naik, Akul; -Roller, Elizabeth Story; Maggioncalda, Emily C.; Lamichhane, Gyanu; Nuermberger, Eric L.; Townsend, Craig A.

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Peptidoglycan compositional analysis of Mycobacterium smegmatis using high-resolution LC-MS

SCIENTIFIC REPORTS

IF3.9

2022-06-30

OAAI

Rimal, Binayak; Senzani, Sibusiso; Ealand, Christopher; Lamichhane, Gyanu; Kana, Bavesh; Kim, Sung Joon

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T405, a New Penem, Exhibits In Vivo Efficacy against M. abscessus and Synergy with β-Lactams Imipenem and Cefditoren

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2022-06-21

OAAI

Rimal, Binayak; Batchelder, Hunter R.; Story-Roller, Elizabeth; Panthi, Chandra M.; Tabor, Chavis; Nuermberger, Eric L.; Townsend, Craig A.; Lamichhane, Gyanu

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Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis The COMRADE Randomized, Phase 2A Clinical Trial

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2022-05-15

OAAI

De Jager, Veronique; Gupte, Nikhil; Nunes, Silvia; Barnes, Grace L.; van Wijk, Rob Christiaan; Mostert, Joni; Dorman, Susan E.; Abulfathi, Ahmed A.; Upton, Caryn M.; Faraj, Alan; Nuermberger, Eric L.; Lamichhane, Gyanu; Svensson, Elin M.; Simonsson, Ulrika S. H.; Diacon, Andreas H.; Dooley, Kelly E.

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Allosteric cooperation in β-lactam binding to a non-classical transpeptidase

ELIFE

IF0

2022-04-27

OAAI

Ahmad, Nazia; Dugad, Sanmati; Chauhan, Varsha; Ahmed, Shubbir; Sharma, Kunal; Kachhap, Sangita; Zaidi, Rana; Bishai, William R.; Lamichhane, Gyanu; Kumar, Pankaj

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Penicillin Binding Proteins and β-Lactamases of Mycobacterium tuberculosis: Reexamination of the Historical Paradigm

MSPHERE

IF3.1

2022-02-23

OAAI

Kumar, Gaurav; Galanis, Christos; Batchelder, Hunter R.; Townsend, Craig A.; Lamichhane, Gyanu

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Potency of Omadacycline against Mycobacteroides abscessus Clinical Isolates In Vitro and in a Mouse Model of Pulmonary Infection

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2022-01-18

OAAI

Nicklas, Danielle A.; Maggioncalda, Emily C.; Story-Roller, Elizabeth; Eichelman, Benjamin; Tabor, Chavis; Serio, Alisa W.; Keepers, Tiffany R.; Chitra, Surya; Lamichhane, Gyanu

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β-Lactam Combinations That Exhibit Synergy against Mycobacteroides abscessus Clinical Isolates

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2021-03-18

OAAI

Story-Roller, Elizabeth; Galanis, Christos; Lamichhane, Gyanu

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Development of a penem antibiotic against Mycobacteroides abscessus

COMMUNICATIONS BIOLOGY

IF5.1

2020-12-07

OAAI

Batchelder, Hunter R.; Story-Roller, Elizabeth; Lloyd, Evan P.; Kaushik, Amit; Bigelow, Kristina M.; Maggioncalda, Emily C.; Nuermberger, Eric L.; Lamichhane, Gyanu; Townsend, Craig A.

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Research Directions