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Rilzabrutinib, a reversible covalent Bruton's tyrosine kinase inhibitor: Absorption, metabolism, excretion, and absolute bioavailability in healthy participants Ucpinar, Sibel; Smith, Patrick F.; Long, Li; Li, Fujun; Yan, Hui; Wadhwa, Jyoti; Chu, Katherine A.; Shu, Jin; Nunn, Philip; Li, Mengyao Share Save
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Assessing the Combined Public Health Impact of Pharmaceutical Interventions on Pandemic Transmission and Mortality: An Example in SARS CoV-2 Kamal, Mohamed A.; Kuznik, Andreas; Qi, Luyuan; Wiecek, Witold; Hussein, Mohamed; Hassan, Hazem E.; Patel, Kashyap; Obadia, Thomas; Toroghi, Masood Khaksar; Conrado, Daniela J.; Al-Huniti, Nidal; Casciano, Roman; O'Brien, Meagan P.; Barnabas, Ruanne, V; Cohen, Myron S.; Smith, Patrick F. Share Save
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A thorough QTc study to evaluate the effects of oral rilzabrutinib administered alone and with ritonavir in healthy subjects Ucpinar, Sibel; Darpo, Borje; Neale, Ann; Nunn, Philip; Shu, Jin; Chu, Katherine A.; Kavanagh, Marianne; Xue, Hongqi; Phiasivongsa, Pasit; Thomas, Dolca; Smith, Patrick F. Share Save
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Phase 1 clinical trial evaluating safety, exposure and pharmacodynamics of BTK inhibitor tolebrutinib (PRN2246, SAR442168) Owens, Timothy D.; Smith, Patrick F.; Redfern, Andrew; Xing, Yan; Shu, Jin; Karr, Dane E.; Hartmann, Sonja; Francesco, Michelle R.; Langrish, Claire L.; Nunn, Philip A.; Gourlay, Steven G. Share Save
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Model-Informed Drug Development for Anti-Infectives: State of the Art and Future Rayner, Craig R.; Smith, Patrick F.; Andes, David; Andrews, Kayla; Derendorf, Hartmut; Friberg, Lena E.; Hanna, Debra; Lepak, Alex; Mills, Edward; Polasek, Thomas M.; Roberts, Jason A.; Schuck, Virna; Shelton, Mark J.; Wesche, David; Rowland-Yeo, Karen Share Save
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Pharmacologic effects of oseltamivir in immunocompromised adult patients as assessed by population PK/PD analysis and drug-disease modelling for dosing regimen optimization Sturm, Stefan; Lemenuel-Diot, Annabelle; Patel, Kashyap; Gibiansky, Leonid; Bhardwaj, Rajinder; Smith, Patrick F.; Dang, Steve; Zwanziger, Elke; Nasmyth-Miller, Clare; Ravva, Patanjali Share Save
Timing of Antiviral Treatment Initiation is Critical to Reduce SARS-CoV-2 Viral Load Goncalves, Antonio; Bertrand, Julie; Ke, Ruian; Comets, Emmanuelle; de Lamballerie, Xavier; Malvy, Denis; Pizzorno, Andres; Terrier, Olivier; Calatrava, Manuel Rosa; Mentre, France; Smith, Patrick; Perelson, Alan S.; Guedj, Jeremie Share Save
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Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study Hershberger, Ellie; Sloan, Susan; Narayan, Kristin; Hay, Catherine A.; Smith, Patrick; Engler, Rank; Jeeninga, Rienk; Smits, Saskia; Trevejo, Jose; Shriver, Zach; Oldach, David Share Save
Respiratory syncytial virus-A dynamics and the effects of lumicitabine, a nucleoside viral replication inhibitor, in experimentally infected humans Patel, Kashyap; Kirkpatrick, Carl M.; Nieforth, Keith A.; Chanda, Sushmita; Zhang, Qingling; McClure, Matthew; Fry, John; Symons, Julian A.; Blatt, Lawrence M.; Beigelman, Leo; DeVincenzo, John P.; Huntjens, Dymphy R.; Smith, Patrick F. Share Save
A phase I trial of PRN1008, a novel reversible covalent inhibitor of Bruton's tyrosine kinase, in healthy volunteers Smith, Patrick F.; Krishnarajah, Janakan; Nunn, Philip A.; Hill, Ron J.; Karr, Dane; Tam, D.; Masjedizadeh, Mohammad; Funk, Jens O.; Gourlay, Steve G. Share Save
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