Genentech Inc.

学者数182

论文数35

被引数0

关联论文 (35)

发表时间

Molecular basis of CXC chemokine receptor 3 ligand multispecificity CXC趋化因子受体3配体多特异性的分子基础

Science Advances

IF12.5

2026-04-17

OAAI

Alexandre Bouyssou; Dawei Sun; Tricia Zhou; Shannon Smith; Hoangdung Ho; Matthew Johnson; Caleigh Azumaya; Sigrid Noreng; Peter Liu; Shu Ti; Prajakta Joshi; Christine Tam; Ying Yang; Eric Janezic; Laëtitia Comps-Agrar; Matthieu Masureel

Recurrent Genomic Alterations in BCRi-Experienced CLL Patients Treated With Venetoclax: Extended Phase 2 Follow-Up 接受维奈克拉治疗的BCRi经治CLL患者中复发性基因组改变：扩展的2期随访研究

American Journal of Hematology

IF9.9

2026-04-08

OAAI

Jennifer A. Woyach; Relja Popovic; Emily L. Rossi; Sanjana Singh; Toshihiko Oki; Tanya S. Rosenberg; Chen Qian; Michael Moran; Zihuan Liu; Michelle Boyer; Jeffrey Jones; Richard R. Furman; William Wierda; Jason Gotlib; Stephen J. Schuster; Brenda Chyla; Matthew S. Davids

Insights into siRNA Duplex Stability by UV Spectrophotometry Absorbance and Melting Temperature Analyses 通过紫外光谱吸光度和熔融温度分析对siRNA双链稳定性的认识

ACS Omega

IF4.3

2026-04-01

OAAI

Molly S. Blevins; Steven Chin; Natali M. Lelieur; Simeon Flier; Jenny Wang; Amin Famili

Population Pharmacokinetic Analysis of Vixarelimab in Healthy Volunteers and Patients With Chronic Pruritic Conditions Vixarelimab在健康志愿者和慢性瘙痒症患者中的群体药代动力学分析

cpt: pharmacometrics & systems pharmacology

IF0

2026-03-07

OAAI

Fei Tang; Steve Dang; Audrey Arjomandi; Lin Pan; Joy Hsu; Smita Kshirsagar; Nastya Kassir

A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Fenebrutinib and Effect on the QT/QTc Interval in Healthy Participants 一项评估Fenebrutinib安全性、耐受性和药代动力学以及其对QT/QTc间期影响的I期研究

Clinical and Translational Science

IF2.8

2026-03-04

OAAI

Yan Xu; Sonoko Kawakatsu; Denison Kuruvilla; John N. Ratchford; Qi Qi; Malgorzata Sierzega; Lin Pan; Jiajie Yu

BCDX2–CX3 and DX2–CX3 complexes assemble and stabilize RAD51 filaments BCDX2-CX3和DX2-CX3复合物组装和稳定RAD51细丝

Nature

IF48.5

2026-03-02

PREAI

Christopher W. Koo; Jiaqi Xiao; Sebastien Coassolo; Jie Liu; Christine Yu; Caleigh Azumaya; Steven K. Gore; Tommy K. Cheung; Bobby Brillantes; Chris M. Rose; Wolf-Dietrich Heyer; Claudio Ciferri; Stanislau Yatskevich

Understanding real-time water penetration dynamics in tablets using synchrotron X-ray micro-computed tomography 使用同步辐射X射线显微计算机断层扫描技术理解片剂中的实时水渗透动力学

Journal of Pharmaceutical Sciences

IF3.8

2026-02-26

OAAI

Denis Kalugin; Prajwal Thool; Carter Blocka; Ning Zhu; Chen Mao; Lifeng Zhang

Systematic Evaluation of Data-independent Acquisition Workflows for High-Throughput and Low-Input Proteomics Analysis with an Astral Mass Spectrometer 数据独立采集工作流程在高通量、低输入蛋白质组学分析中的系统评价（使用Astral质谱仪）

Journal of Proteome Research

IF3.6

2026-02-25

PREAI

Zhichang Yang; Taylur P. Ma; Meena Choi; Fengchao Yu; Ying Zhu

Unconventional Lysine-Type Lipid Assemblies Enable Efficient Antisense Oligonucleotide Delivery with Distinct Structural Features 非常规赖氨酸型脂质组装体通过独特的结构特征实现高效的反义寡核苷酸递送

Pharmaceutics

IF5.5

2026-02-11

OAAI

Jieyan He; Whitney Shatz-Binder; Alexandra Robles; Nanzhi Zang; Wei Jia; Sakura Sahai; Matthew C. Johnson; Jing Li; Chun-Wan Yen; Shinji Takeoka

Author Correction: Whole-body CD8+ T-cell PET imaging in patients with large B-cell lymphoma before and during CD19-directed CAR T-cell therapy: a phase 2 study 作者更正：大B细胞淋巴瘤患者治疗前及CD19定向CAR T细胞疗法期间全身CD8+ T细胞PET成像：一项2期研究

Nature Communications

IF15.7

2026-02-10

OAAI

Janneke W. de Boer; Kylie Keijzer; Jaap A. van Doesum; Nienke A. M. Smit; Adrienne H. Brouwers; Joyce van Sluis; Marjolijn N. Lub-de Hooge; Frank R. Pierik; Gerwin A. Huls; Lisanne V. van Dijk; Lydia Visser; Arjan Diepstra; Walter Noordzij; Simon P. Williams; Alexander Ungewickell; Sjoerd G. Elias; Elisabeth G. E. de Vries; Anne G. H. Niezink; Tom van Meerten

AI-Based Analysis of Label-Free Live Cell Imaging of T-Cell Mediated Tumor Killing Assay Enables Competitive and Robust Hit Calling 基于AI的T细胞介导的肿瘤杀伤测定的无标记活细胞成像分析可实现竞争性和稳健的命中调用

SLAS Discovery

IF2.7

2026-02-03

OAAI

Josefa Chuh; Daniel Siegismund; John Moffat; Stephan Heyse; Katherine Kozak; Stephan Steigele

High-Resolution Ion Mobility Mass Spectrometry for Separation of Oligonucleotide Phosphorothioate Diastereomers Blevins, M.S.; Du, J.; Aderorho, R.; Lieu, R.; Crittenden, C.M.; Chen, T. 高分辨离子迁移质谱法分离寡核苷酸硫代磷酸酯差向异构体。Anal. Chem. 2026, 98, 3510–3522. [Google Scholar] [CrossRef] [PubMed]

Analytical Chemistry

IF6.7

2026-01-28

PREAI

Molly S. Blevins; Jie Du; Ralph Aderorho; Raymond Lieu; Christopher M. Crittenden; Tao Chen

Multi-Scale Transcriptomics Redefining the Tumor Immune Microenvironment 多尺度转录组学重新定义肿瘤免疫微环境

BioTech

IF3.1

2026-01-25

OAAI

Jing Sun; Yingxue Xiao; Lingling Xie; Dan Qin; Yue Zou; Yingying Liu; Yitong Zhai; Minyi Zhang; Tong Li; Youjin Hao; Bo Li

Long-acting delivery of a model monoclonal antibody from ethylene vinyl acetate implants at a high loading: Drug release and protein stability

Journal of Pharmaceutical Sciences

IF3.8

2026-01-15

PREAI

Yu Tong Tam; Harsh Patel; Jeffrey C. Haley; Alexander Dimmling; Devin B. Tesar; Alavattam Sreedhara

Investigating the SNAC-to-drug ratio for the oral absorption of cyanocobalamin in rats

Journal of Pharmaceutical Sciences

IF3.8

2026-01-13

PREAI

Po-Chang Chiang; Jia Liu; Karthik Nagapudi; Jodie Pang; Emile Plise; Michael Dolton; Matthew R. Durk

Dictionary of human intestinal organoid responses to secreted niche factors at single cell resolution 单细胞分辨率下人类肠道类器官对分泌性微环境因子的响应词典

Nature Communications

IF15.7

2026-01-09

OAAI

Meghan M. Capeling; Bob Chen; Kazeera Aliar; Elisa Penna; Veronica Ibarra Lopez; Conrad Foo; Sandra Rost; Loryn Holokai; Xinming Tong; Devan Phillips; Caden Sweet; Jing Li; Sharmila Chatterjee; Elizabeth Skippington; Zora Modrusan; Lisa M. McGinnis; Runmin Wei; Mary Keir; Orit Rozenblatt-Rosen; Michelle B. Chen

Future Directions in Drug-Drug Interaction Evaluations: Industry Perspective on the ICH M12 Guidance 药物相互作用评价的未来方向：行业对ICH M12指导原则的视角

Drug Metabolism and Pharmacokinetics

IF2.2

2025-12-12

PREAI

Kenichi Umehara; Andrew Harrell; Chandra Prakash; Constanze Hilgendorf; T.Eric Ballard; Felix Huth; Justine Badée; Licong Jiang; Manoli Vourvahis; Natasa Pajkovic; Neil Parrott; Nilay Thakkar; Patrik Marroum; Ronald Laethem; Shiyao Xu; Yuan Chen

Chemically-inducible CRISPR/Cas9 circuits for ultra-high dynamic range gene perturbation 化学诱导的CRISPR/Cas9回路用于超高动态范围基因扰动

Nature Communications

IF15.7

2025-12-12

OAAI

Rajini Srinivasan; Tao Sun; Azalia Sandles; Diana Wu; Liang Wang; Hetal Patel; Ryan Pabalate; Maram Bader; Amy Heidersbach; Clark Ho; Shiqi Xie; Andrew Ng; Benjamin Haley

HTRA1/lncRNA HTRA1-AS1 dominates in age-related macular degeneration reticular pseudodrusen genetic risk with no complement involvement HTRA1/lncRNA HTRA1-AS1在年龄相关性黄斑变性网状假性玻璃疣遗传风险中占主导地位，且不涉及补体。

Nature Communications

IF15.7

2025-12-08

OAAI

Samaneh Farashi; Carla J. Abbott; Brendan R. E. Ansell; Zhichao Wu; Lebriz Altay; Ella Arnon; Louis Arnould; Yelena Bagdasarova; Konstantinos Balaskas; Fred K. Chen; Emily Chew; Itay Chowers; Steven Clarke; Catherine Cukras; Cécile Delcourt; Marie-Noëlle Delyfer; Anneke I. den Hollander; Sascha Fauser; Robert P. Finger; Pierre-Henry Gabrielle; Jiru Han; Lauren A. B. Hodgson; Ruth Hogg; Frank G. Holz; Carel Hoyng; Himeesh Kumar; Eleonora M. Lad; Aaron Lee; Ulrich F. O. Luhmann; Matthias M. Mauschitz; Amy J. McKnight; Samuel McLenachan; Aniket Mishra; Ismail Moghul; Luz D. Orozco; Danuta M. Sampson; Liam W. Scott; Vasilena Sitnilska; Scott Song; Amy Stockwell; Anand Swaroop; Jan H. Terheyden; Liran Tiosano; Adnan Tufail; Brian L. Yaspan; Alice Pébay; Erica L. Fletcher; Robyn H. Guymer; Melanie Bahlo

Cell type inference in cell-free nucleic acid liquid biopsy 细胞游离核酸液体活检中的细胞类型推断

Nature Biotechnology

IF41.7

2025-11-26

PREAI

Sevahn K. Vorperian; Lucas M. Dennis; Anna Hupalowska; Jennifer E. Rood; Stephen R. Quake