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S

Samuel W. Du

school of medicine
H指数:15
被引数:1,643

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Lipid-driven membrane remodeling engages a lysosome-dependent adaptive repair program during retinal aging

脂质驱动的膜重塑在视网膜衰老期间启动了溶酶体依赖的适应性修复程序

Molecular Neurodegeneration
IF17.5
2026-08-290
OA
Emily Tom; Fangyuan Gao; Carolina N. Franco; Adrian Wong; Nathan Kemmerer; Zichen Wang; Amit Jairaman; Qianlan Xu; Yinyin Zhuang; Samuel W. Du; Grazyna Palczewska; Krzysztof Palczewski; Itay Budin; Shivashankar Othy; Xiaoyu Shi; Vera L. Bonilha; Johannes Schoeneberg; Karl J. Wahlin; Lauren V. Albrecht; Dorota Skowronska-Krawczyk
A combinatorial synthetic strategy for developing genome-editing protein-delivery agents targeting mouse retina

开发针对小鼠视网膜的基因组编辑蛋白递送剂的组合合成策略

Nature Communications
IF15.7
2026-02-070
OAAI
Jianye Zhang; Rafał Hołubowicz; Roman Smidak; Yulun Hu; Samuel W. Du; Jiin H. Felgner; Grazyna Palczewska; Carolline Rodrigues Menezes; Eleonora Risaliti; Zhiqian Dong; Xiuli Ma; Mojtaba H. Shayegan; Paul Z. Chen; Li Xing; Maria Hołubowicz; Bowen Li; David R. Liu; Philip L. Felgner; Gregory P. Tochtrop; Krzysztof Palczewski
MFRP is a molecular hub that organizes the apical membrane of RPE cells by engaging in interactions with specific proteins and lipids

MFRP是一种分子枢纽，通过与特定蛋白质和脂质相互作用来组织RPE细胞的顶膜。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2025-04-180
OA
Tworak, Aleksander; Smidak, Roman; Menezes, Carolline Rodrigues; Du, Samuel W.; Suh, Susie; Choi, Elliot H.; Imanishi, Sanae S.; Dong, Zhiqian; Lewandowski, Dominik; Fong, Kristen E.; Grigorean, Gabriela; Pinto, Antonio F. M.; Xu, Qianlan; Skowronska-Krawczyk, Dorota; Blackshaw, Seth; Imanishi, Yoshikazu; Palczewski, Krzysztof
Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations
NATURE BIOMEDICAL ENGINEERING
IF26.6
2024-11-280
OAAI
Holubowicz, Rafal; Du, Samuel W.; Felgner, Jiin; Smidak, Roman; Choi, Elliot H.; Palczewska, Grazyna; Menezes, Carolline Rodrigues; Dong, Zhiqian; Gao, Fangyuan; Medani, Omar; Yan, Alexander L.; Holubowicz, Maria W.; Chen, Paul Z.; Bassetto, Marco; Risaliti, Eleonora; Salom, David; Workman, J. Noah; Kiser, Philip D.; Foik, Andrzej T.; Lyon, David C.; Newby, Gregory A.; Liu, David R.; Felgner, Philip L.; Palczewski, Krzysztof
In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration

体内碱基编辑可在早发性遗传性视网膜变性的小鼠模型中拯救视锥细胞

NATURE COMMUNICATIONS
IF15.7
2022-04-0548
OAAI
Choi, Elliot H.; Suh, Susie; Foik, Andrzej T.; Leinonen, Henri; Newby, Gregory A.; Gao, Xin D.; Banskota, Samagya; Thanh Hoang; Du, Samuel W.; Dong, Zhiqian; Raguram, Aditya; Kohli, Sajeev; Blackshaw, Seth; Lyon, David C.; Liu, David R.; Palczewski, Krzysztof

研究方向

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K
Krzysztof Palczewski
H 指数:115论文数:738被引数:5.0万
E
Elliot H. Choi
H 指数:25论文数:75被引数:2,310
S
Shaun W. Jackson
H 指数:27论文数:68被引数:3,231
D
David J. Rawlings
H 指数:77论文数:406被引数:2.2万
P
Paul Chen
H 指数:32论文数:104被引数:3,045
T
Tanvi Arkatkar
H 指数:16论文数:30被引数:1,099
D
David R. Liu
H 指数:124论文数:387被引数:7.8万
R
Roman Šmidák
H 指数:10论文数:25被引数:396
G
Gregory A. Newby
H 指数:42论文数:117被引数:1.5万
F
Fangyuan Gao
H 指数:21论文数:93被引数:1,999