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D

Dirk Daelemans

ku leuven

43H指数
296论文数
1.0W被引数
收录论文 144
发表时间
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Synthesis of 1,3,5-Triazine-Indole Conjugates as Broad-Spectrum Coronavirus Entry Inhibitors1,3,5-三嗪-吲哚共轭物的合成及其作为广谱冠状病毒入侵抑制剂的用途
errChemMedChem
IF3.4
err2026-09-07
err0
PREAI
errShazia Asghar; Leentje Persoons; Yanicka Smolders; Niels Willems; Dirk Daelemans; Steven De Jonghe; Najim A. Al-Masoudi; Shahid Hameed
err分享
err收藏
Discovery of pyridine formyl hydrazide derivatives as potent non-nucleoside RSV polymerase inhibitors吡啶甲酰肼衍生物作为强效非核苷类呼吸道合胞病毒聚合酶抑制剂的发现
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-08-21
err0
PREAI
errXin Li; Jinyuan Wu; Lin Zheng; Sining Tao; Wenjing Jin; Xiaolei Zhao; Steven De Jonghe; Leentje Persoons; Dirk Daelemans; Xinyong Liu; Yuanhui Fu; Dongwei Kang; Ni Gao
err分享
err收藏
Preclinical characterization of a reversible XPO1 inhibitor for cancer therapy一种可逆性XPO1抑制剂用于癌症治疗的临床前表征
errNature Communications
IF15.7
err2026-07-22
err0
errOAAI
errJanne Van Hauwenhuyse; Felien Reniers; Leentje Persoons; Sam Noppen; Casey E. Wing; Ashley B. Niesman; Ho Yee Joyce Fung; Els Vanstreels; Maarten Jacquemyn; Eline Boel; Ann Vankerckhoven; Yani Berckmans; Bert Kwanten; An Coosemans; Guy Van den Mooter; Yuh Min Chook; Wim Dehaen; Dirk Daelemans
err分享
err收藏
Design, synthesis, and evaluation of novel C6-substituted purine-isoxazole derivatives and their Re(I) tricarbonyl complexes: antiproliferative activity and integrated in silico studyC6取代的嘌呤-异噁唑衍生物及其Re(I)三羰基配合物的设计、合成与评价：抗增殖活性及整合的体外计算机研究
errJournal of Molecular Structure
IF4.7
err2026-05-23
err0
PREAI
errBenkovic, Martina Piskor; Sacer, Leon; Abhirami, Rajaram; Singh, Sanjeev Kumar; Sedic, Mirela; Persoons, Leentje; Daelemans, Dirk; Peric, Berislav; Kirin, Srecko, I; Raic-Malic, Silvana
err分享
err收藏
ADA2-deficient cells exhibit increased levels of cell death and metabolic disturbancesADA2缺陷细胞表现出细胞死亡和代谢紊乱水平升高
errCell Death Discovery
IF7
err2026-03-23
err0
PREAI
errEhlers, Lisa; Wouters, Marjon; Pillay, Bethany; Delafontaine, Selket; Bucciol, Giorgia; Baggio, Marco; Dzhus, Mariia; Hombrouck, Anneleen; Damerau, Alexandra; De Somer, Lien; Schrijvers, Rik; Vanderschueren, Steven; Jacquemyn, Maarten; Kallinich, Tilmann; Daelemans, Dirk; Ghesquiere, Bart; Agostinis, Patrizia; Moens, Leen; Meyts, Isabelle
err分享
err收藏
Benzoxazole Iminocoumarins as Multifunctional Heterocycles with Optical pH-Sensing and Biological Properties: Experimental, Spectroscopic and Computational Analysis苯并噁唑氨基香豆素作为具有光学pH传感和生物特性的多功能杂环：实验、光谱和计算分析
errChemosensors
IF3.7
err2026-01-04
err0
errOAAI
errMarina Galić; Ana Čikoš; Leentje Persoons; Dirk Daelemans; Karolina Vrandečić; Maja Karnaš; Marijana Hranjec; Robert Vianello
err分享
err收藏
Quinoline and coumarin isoxazole derivatives: synthesis; antitumor evaluation and molecular docking studies with Bcl-2喹啉和香豆素异恶唑衍生物：合成；抗肿瘤评价与Bcl-2的分子对接研究
errRSC Adv.
IF0
err2025-12-17
err0
errOAAI
errMartina Piškor; Marina Ter; Leentje Persoons; Dirk Daelemans; Ahmed Adel; Mutasem O. Taha; Astrid Milić; Mirela Sedić; Silvana Raić-Malić
err分享
err收藏
Sec61 translocon inhibitor flavitransin blocks selectively dengue virus polyprotein insertion in the ER with pan-orthoflavivirus antiviral potencySec61转位通道抑制剂flavitransin选择性地阻断登革病毒多聚蛋白在ER中的插入，并具有广谱正黄病毒抗病毒活性。
errCell Reports
IF6.9
err2025-12-04
err0
errOAAI
errMarijke Verhaegen; Marianne Croonenborghs; Nidhi Sorout; Andrea Sartori; Becky Provinciael; Eef Meyen; Joren Stroobants; Robin Hermans; Maarten Jacquemyn; Dirk Daelemans; Ana Lucia Rosales-Rosas; Leen Delang; Piet Maes; Enno Hartmann; Volkhard Helms; Kurt Vermeire
err分享
err收藏
Human and viral chemokines differentially modulate G protein signaling, β-arrestin recruitment and chemotaxis mediated by the viral G protein-coupled receptor ORF74人类和病毒的化学引诱物蛋白（chemokines）差异性地调节病毒G蛋白偶联受体ORF74介导的G蛋白信号传导、β抑制蛋白（β-arrestin）募集和趋化性。
errCell Communication and Signaling
IF8.9
err2025-11-23
err0
errOAAI
errQianqian Kong; Brent Van Bosstraeten; Maarten Jacquemyn; Dirk Daelemans; Steven De Jonghe; Dominique Schols; Tom Van Loy
err分享
err收藏
SINE compounds activate exportin 1 degradation through an allosteric mechanismSINE化合物通过别构机制激活exportin 1的降解
errNature Chemical Biology
IF13.7
err2025-11-21
err0
PREAI
errCasey E. Wing; Ho Yee Joyce Fung; Bert Kwanten; Tolga Cagatay; Ashley B. Niesman; Maarten Jacquemyn; Mehdi Gharghabi; Brecht Permentier; Binita Shakya; Rhituparna Nandi; Joseph M. Ready; Trinayan Kashyap; Sharon Shacham; Yosef Landesman; Rosa Lapalombella; Dirk Daelemans; Yuh Min Chook
err分享
err收藏
Mechanochemical Solvent-Free Synthesis and Biological Profiling of Novel 2-Hydrazone-Bridged Benzothiazoles as Potent Anticancer Agents
errSUSTAINABLE CHEMISTRY
IF4.2
err2025-11-03
err0
PREAI
errSokol, Ivana; Mlinar, Hanja; Grgic, Dajana Kucic; Persoons, Leentje; Daelemans, Dirk; Mihovilovic, Moris; Kraljevic, Tatjana Gazivoda
err分享
err收藏
Sustainable synthesis, dyeing performance, and biological evaluation of novel benzothiazole-based disperse azo dyes可持续合成、染色性能及新型苯并噻唑基分散偶氮染料的生物评价
errDyes and Pigments
IF4.2
err2025-10-17
err0
PREAI
errAnja Beč; Magda Relić; Mario Herceg; Ana Sutlović; Martinia Ira Glogar; Mario Cetina; Mihailo Banjanac; Vedrana Radovanović; Leentje Persoons; Dirk Daelemans; Livio Racané
err分享
err收藏
Benzoxazole-Acrylonitriles: Dual Bioactivity and DNA Binding from a Sustainable Synthetic ApproachBenzoxazole-Acrylonitriles: 双重生物活性与DNA结合：一种可持续合成方法
errCHEMMEDCHEM
IF3.4
err2025-09-01
err0
PREAI
errGalic, Marina; Rohtek, Tamara; Persoons, Leentje; Daelemans, Dirk; Banjanac, Mihailo; Bruketa, Tea; Stojkovic, Marijana Radic; Hranjec, Marijana
err分享
err收藏
Inhibition of lysosomal degradation increases expression of mutant ADA2 in DADA2 monocytes溶酶体降解的抑制增加了DADA2单核细胞中突变型ADA2的表达
errJournal of Allergy and Clinical Immunology
IF11.2
err2025-06-20
err0
errOAAI
errLisa Ehlers; Marjon Wouters; Bethany Pillay; Selket Delafontaine; Mariia Dzhus; Marco Baggio; Tim Niehues; Gregor Dückers; Lieve Sevenants; Kristina Casteels; Lien De Somer; Rik Schrijvers; Steven Vanderschueren; Maarten Jacquemyn; Dirk Daelemans; Anneleen Hombrouck; Eugene P. Chambers; Thomas Tousseyn; Giorgia Bucciol; Patrizia Agostinis; Leen Moens; Isabelle Meyts
err分享
err收藏
A Sustainable Synthesis of Novel 2-(3,4-Disubstituted phenyl)benzoxazole Derivatives and Their Antiproliferative and Antibacterial Evaluation
errMOLECULES
IF4.6
err2025-04-15
err0
errOAAI
errRakas, Anja; Persoons, Leentje; Daelemans, Dirk; Grgic, Dajana Kucic; Kraljevic, Tatjana Gazivoda
err分享
err收藏
Optimizing biofilm inhibitors: Balancing activity and toxicity in 2N-aminated 5-aryl-2-aminoimidazoles
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2025-04-01
err0
PREAI
errMaetens, Lynn; Maiti, Banibrata; Cools, Freya; Verheye, Stefan; Daelemans, Dirk; Persoons, Leentje; Temmerman, Liesbet; Kieswetter, Amanda; Van der Eycken, Erik V.; Coppola, Guglielmo A.; Vackier, Thijs; Steenackers, Hans P.
err分享
err收藏
A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses
errPLOS PATHOGENS
IF4.9
err2025-02-11
err0
errOAAI
errVan Loy, Benjamin; Pujol, Eugenia; Kamata, Kenichi; Lee, Xiao Yin; Bakirtzoglou, Nikolai; Van Berwaer, Ria; Vandeput, Julie; Mestdagh, Cato; Persoons, Leentje; De Wijngaert, Brent; Goovaerts, Quinten; Noppen, Sam; Jacquemyn, Maarten; Ahmadzadeh, Kourosh; Bernaerts, Eline; Martin-Lopez, Juan; Escriche, Celia; Vanmechelen, Bert; Krasniqi, Besir; Singh, Abhimanyu K.; Daelemans, Dirk; Maes, Piet; Matthys, Patrick; Dehaen, Wim; Rozenski, Jef; Das, Kalyan; Voet, Arnout; Vazquez, Santiago; Naesens, Lieve; Stevaert, Annelies
err分享
err收藏
Biological assessments of novel ultrasound-synthesized 2-arylbenzimidazole derivatives: antiproliferative and antibacterial effects新型超声合成的2-芳基苯并咪唑衍生物的生物评估：抗增殖和抗菌作用
errRSC MEDICINAL CHEMISTRY
IF3.6
err2025-01-01
err0
PREAI
errSokol, Ivana; Rakas, Anja; Grgic, Dajana Kucic; Persoons, Leentje; Daelemans, Dirk; Kraljevic, Tatjana Gazivoda
err分享
err收藏
Ibetazol, a novel inhibitor of importin β1-mediated nuclear import
errCOMMUNICATIONS BIOLOGY
IF5.1
err2024-11-23
err0
PREAI
errVercruysse, Thomas; Vanstreels, Els; Jacquemyn, Maarten; Boland, Sandro; Kilonda, Amuri; Allasia, Sara; Vandecaetsbeek, Ilse; Klaassen, Hugo; Versele, Matthias; Chaltin, Patrick; Marchand, Arnaud; Daelemans, Dirk
err分享
err收藏
Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation partially regulates aerobic activities in human hepatocytes and HepG2 cells (vol 227, 116445, 2024)
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2024-11-01
err0
PREAI
errDe Vos, Kristof; Mavrogiannis, Adamantios; Wolters, Justina Clarinda; Schlenner, Susan; Calabuig, Alvaro Cortes; Wierda, Keimpe; Chinnaraj, Reena; Dermesrobian, Vera; Armoudjian, Yeghig; Jacquemyn, Maarten; Corthout, Nikky; Daelemans, Dirk; Annaert, Pieter
err分享
err收藏

研究方向

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