Junjiu Huang - Publications, H-index & Citations

黄

黄军就 (Junjiu Huang)

Sun Yat-Sen University

38H指数

148论文数

6.1K被引数

收录论文 86

发表时间

Long-term in vivo CRISPR/Cas9 gene editing in liver triggers host immunity and clonal mutations in DNA damage response genes beyond off-target effects 长期在肝脏中进行体内CRISPR/Cas9基因编辑会触发宿主免疫反应并在DNA损伤应答基因中引发克隆突变，这超出了脱靶效应的影响

Protein & Cell

IF0

2026-08-21

OAAI

Tianqi Cao; Ao Zhang; Wenlian Wu; Jinkun Wen; Ming Mu; Simiao Liu; Yuxi Chen; Di Zhang; Haiying Liu; Shanjun Deng; Xionglei He; Junjiu Huang; null

A Novel X-linked Retinitis Pigmentosa Beagle Dog Model for Ophthalmic Research Established Rapidly by Editing the RPGR Gene in Zygotes 通过在受精卵中编辑RPGR基因快速建立的新型X连锁色素性视网膜炎比格犬模型，用于眼科研究。

Experimental Eye Research

IF2.7

2025-10-15

PREAI

Dongchun Xie; Jiahui Wang; Li Huang; Zhihong Zhao; Ronggen Wang; Haibin Long; Qingchun Ni; Haiying Liu; Minhua Hu; Junjiu Huang

Clinical patterns of thalidomide in the treatment of transfusion-dependent β-thalassaemia in children: a prospective single-arm study in China 沙利度胺治疗输血依赖性β-地中海贫血患儿的临床模式：一项在中国进行的前瞻性单臂研究

Annals of Medicine

IF4.3

2025-10-11

OAAI

Xinyu Li; Weicong Hong; Jinni Wu; Qianyi Liu; Yong Liu; Shuting Hu; Luhong Xu; Honggui Xu; Danping Zhong; Junjiu Huang; Jianpei Fang

Insufficient telomeric DNA damage response promotes chromosomal instability in aged oocytes 端粒DNA损伤反应不足促进衰老卵母细胞中的染色体不稳定

Science Bulletin

IF21.1

2025-08-25

PREAI

Tianqi Cao; Simiao Liu; Fang Wang; Min Gao; Wenlian Wu; Yanling Qiu; Ming Mu; Tengteng Xu; Jinkun Wen; Yuxi Chen; Haiying Liu; Xiqian Zhang; David L. Keefe; Lin Liu; Fenghua Liu; Junjiu Huang

Hyperandrogen-induced imbalance of FOXO4-AR regulatory loop contributes to ovulatory disorders in polycystic ovary syndrome 高雄激素诱导的FOXO4-AR调控环路失衡对多囊卵巢综合征中的排卵障碍有贡献。

Molecular Therapy Nucleic Acids

IF6.1

2025-04-20

OAAI

Ruiqiong Zhou; Zhaoyi Wang; Mei Dong; Songlu Wang; Xiangyuan Li; Junjiu Huang; Xiqian Zhang; Fenghua Liu

Age-associated accumulation of RAB9 disrupts oocyte meiosis 与年龄相关的RAB9积累破坏卵母细胞减数分裂

AGING CELL

IF7.1

2024-12-15

OAAI

Gao, Min; Wang, Fang; Xu, Tengteng; Qiu, Yanling; Cao, Tianqi; Liu, Simiao; Wu, Wenlian; Zhou, Yitong; Liu, Haiying; Liu, Fenghua; Huang, Junjiu

An integrated transcriptomic analysis of brain aging and strategies for healthy aging 脑老化的整合转录组学分析和健康老化策略

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2024-12-05

OAAI

Liu, Haiying; Nie, Xin; Wang, Fengwei; Chen, Dandan; Zeng, Zhuo; Shu, Peng; Huang, Junjiu

Rationally designed Campylobacter jejuni Cas9 enables efficient gene activation and base editing

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2024-12-01

OAAI

Chen, Yuxi; Kang, Rui; Jiang, Yuanling; Zheng, Qi; Yang, Yue; Liu, Jiaqi; Wu, Guanglan; Zhao, Weijun; Li, Zhan; Peng, Chengxiang; Zhang, Pengfei; Peng, Fei; Liu, Qianyi; Hu, Sihui; Luo, Xiao; Wu, Guifang; Cui, Kaixin; Huang, Junjiu; Wang, Yongming; Zhou, Songyang; Liang, Puping

Updated Safety and Efficacy Results of RM-001, Autologous HBG1/2 Promoter-Modified CD34+Hematopoietic Stem and Progenitor Cells, in Treating Transfusion-Dependent β-Thalassemia RM-001的安全性及有效性最新结果，RM-001为自体HBG1/2启动子修饰的CD34+造血干细胞和祖细胞，用于治疗输血依赖型β-地中海贫血

BLOOD

IF23.1

2024-11-05

PREAI

Liu, Rongrong; Wang, Li; Xu, Hui; Fang, Jianpei; Liu, Sixi; Yin, Xiaolin; Liang, Junbin; Li, Xinyu; Li, Yue; Yang, Gaohui; Li, Yaoyun; Zhou, Yali; Shi, Lei; Lai, Yongrong; Huang, Junjiu; Zhang, Xinhua

First-in-Human Study of Autologous HBA2-Edited CD34+Hematopoietic Stem and Progenitor Cells in Alpha-Thalassemia with Constant Spring Mutation 首次人体研究：自体HBA2编辑的CD34+造血干细胞和祖细胞在常春藤突变型α地中海贫血中的应用

BLOOD

IF23.1

2024-11-05

PREAI

Wang, Li; Xu, Hui; Liang, Junbin; Li, Yaoyun; Cheng, Lin; Luo, Ying; Huang, Liancheng; Shi, Lei; Zeng, Lihong; Luo, Rongrong; Xiao, Bin; Liu, Meiping; Huang, Liping; Xiao, Zhendong; Zhang, Xinhua; Huang, Junjiu

NSUN2 is critical for mouse oocyte meiosis and early embryonic development

REPRODUCTION

IF3.7

2024-09-04

PREAI

Xu, Tengteng; Gao, Min; Zhang, Ling; Cao, Tianqi; Qiu, Yanling; Liu, Simiao; Wu, Wenlian; Zhou, Yitong; Liu, Haiying; Zhang, Rui; Ruan, Xiaohong; Huang, Junjiu

YTHDC1 delays cellular senescence and pulmonary fibrosis by activating ATR in an m6A-independent manner YTHDC1通过m6A-independent激活ATR延缓细胞衰老和肺纤维化

EMBO JOURNAL

IF8.3

2023-12-15

OAAI

Zhang, Canfeng; Chen, Liping; Xie, Chen; Wang, Fengwei; Wang, Juan; Zhou, Haoxian; Liu, Qianyi; Zeng, Zhuo; Li, Na; Huang, Junjiu; Zhao, Yong; Liu, Haiying

RBMX involves in telomere stability maintenance by regulating TERRA expression

PLOS GENETICS

IF3.7

2023-09-27

OAAI

Liu, Jingfan; Zheng, Tian; Chen, Dandan; Huang, Junjiu; Zhao, Yong; Ma, Wenbin; Liu, Haiying

Transplantation of Gelatin Microspheres Loaded with Wharton's Jelly Derived Mesenchymal Stem Cells Facilitates Cartilage Repair in Mice

TISSUE ENGINEERING AND REGENERATIVE MEDICINE

IF4.1

2023-09-09

OAAI

Chen, Xiaolin; Huang, Sunxing; Niu, Yongxia; Luo, Mingxun; Liu, Haiying; Jiao, Yiren; Huang, Junjiu

Nme2Cas9-mediated therapeutic editing in inhibiting angiogenesis after wet age-related macular degeneration onset

CLINICAL AND TRANSLATIONAL MEDICINE

IF6.8

2023-08-20

OAAI

Hu, Sihui; Chen, Yuxi; Xie, Dongchun; Xu, Kan; Fu, Yunzhao; Chi, Wei; Liu, Haiying; Huang, Junjiu

Insufficient HtrA2 causes meiotic defects in aging germinal vesicle oocytes

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY

IF4.7

2022-12-20

OAAI

Gao, Min; Qiu, Yanling; Cao, Tianqi; Li, Dungao; Wang, Jingwen; Jiao, Yiren; Chen, Zhiyun; Huang, Junjiu

METTL3-mediated m6A modification stabilizes TERRA and maintains telomere stability

NUCLEIC ACIDS RESEARCH

IF13.1

2022-11-18

OAAI

Chen, Liping; Zhang, Canfeng; Ma, Wenbin; Huang, Junjiu; Zhao, Yong; Liu, Haiying

PDCL2 is essential for spermiogenesis and male fertility in mice

CELL DEATH DISCOVERY

IF7

2022-10-17

OAAI

Li, Minyan; Chen, Yuxi; Ou, Jianping; Huang, Junjiu; Zhang, Xiya

Folic Acid Preconditioning Alleviated Radiation-Induced Ovarian Dysfunction in Female Mice

FRONTIERS IN NUTRITION

IF5.1

2022-06-28

OAAI

Zhang, Qianyu; Wei, Zhifu; Weng, Huinan; Chen, Ye; Zhang, Jie; Mei, Shiwei; Wei, Jiahui; Zhu, Xiulan; Nong, Yingqi; Ruan, Jianxing; Liu, Wenjuan; Zhou, Ruiqiong; Wang, Fang; Xie, Yanni; Huang, Junjiu; Zhang, Xiqian; Liu, Fenghua

TIN2 deficiency leads to ALT-associated phenotypes and differentiation defects in embryonic stem cells

STEM CELL REPORTS

IF5.1

2022-05-01

OAAI

Yin, Shanshan; Zhang, Fangyingnan; Song Lin; Wei Chen; Kai Weng; Dan Liu; Wang, Chuanle; He, Zibin; Chen, Yuxi; Ma, Wenbin; Huang, Junjiu; Yan Huang; Zhou Songyang

研究方向