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A

Astrid Magenau

University of Konstanz
H指数:31
被引数:3,827

个人简介

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荣誉奖项

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Targeting the NPY/NPY1R signaling axis in mutant p53-dependent pancreatic cancer impairs metastasis

靶向突变型p53依赖性胰腺癌中的NPY/NPY1R信号轴抑制了转移

SCIENCE ADVANCES
IF12.5
2025-03-140
PRE
Chambers, Cecilia R.; Watakul, Supitchaya; Schofield, Peter; Howell, Anna E.; Zhu, Jessie; Tran, Alice M. H.; Kuepper, Nadia; Reed, Daniel A.; Murphy, Kendelle J.; Channon, Lily M.; Pereira, Brooke A.; Tyma, Victoria M.; Lee, Victoria; Trpceski, Michael; Henry, Jake; Melenec, Pauline; Abdulkhalek, Lea; Nobis, Max; Metcalf, Xanthe L.; Ritchie, Shona; Cadell, Antonia; Stoehr, Janett; Magenau, Astrid; Chacon-Fajardo, Diego; Chitty, Jessica L.; O'Connell, Savannah; Zaratzian, Anaiis; Tayao, Michael; Da Silva, Andrew; Lyons, Ruth J.; Goldstein, Leonard D.; Dale, Ashleigh; Rookyard, Alexander; Connolly, Angela; Crossett, Ben; Tran, Yen T. H.; Kaltzis, Peter; Vennin, Claire; Dinevska, Marija; Croucher, David R.; Samra, Jaswinder; Mittal, Anubhav; Weatheritt, Robert J.; Philp, Andrew; Del Monte-Nieto, Gonzalo; Zhang, Lei; Enriquez, Ronaldo F.; Cox, Thomas R.; Shi, Yan-Chuan C.; Pinese, Mark; Waddell, Nicola; Sim, Hao-Wen; Wang, Yingxiao; Joshua, Anthony M.; Chantrill, Lorraine; Evans, Thomas R. Jeffry; Gill, Anthony J.; Morton, Jennifer P.; Pajic, Marina; Herzog, Herbert; Timpson, Paul; Herrmann, David
Impact of symptom and functional burden on survival in pancreatic ductal adenocarcinoma (PDAC)

症状和功能负担对胰腺导管腺癌（PDAC）生存期的影响

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Pitiyarachchi, O.; Lin, F. P.; Spooner, A.; Sharbeen, G.; Barker, H. P.; Thornton, K.; Collignon, E.; Ballinger, M. L.; Thomas, D. M.; Magenau, A.; Porazinski, S.; Raina, A.; Sjoquist, K. M.; Chantrill, L. A.; Gebski, V.; Sowmya, A.; Timpson, P.; Pajic, M.; Goldstein, D.; Phillips, P. A.
Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response

暂时分辨的蛋白质组学将nidogen-2鉴定为胰腺癌的共靶标，其调节纤维化和治疗反应

SCIENCE ADVANCES
IF12.5
2024-07-052
OAAI
Pereira, Brooke A.; Ritchie, Shona; Chambers, Cecilia R.; Gordon, Katie A.; Magenau, Astrid; Murphy, Kendelle J.; Nobis, Max; Tyma, Victoria M.; Liew, Ying Fei; Lucas, Morghan C.; Naeini, Marjan M.; Barkauskas, Deborah S.; Chacon-Fajardo, Diego; Howell, Anna E.; Parker, Amelia L.; Warren, Sean C.; Reed, Daniel A.; Lee, Victoria; Metcalf, Xanthe L.; Lee, Young Kyung; O'Regan, Luke P.; Zhu, Jessie; Trpceski, Michael; Fontaine, Angela R. M.; Stoehr, Janett; Rouet, Romain; Lin, Xufeng; Chitty, Jessica L.; Porazinski, Sean; Wu, Sunny Z.; Filipe, Elysse C.; Cadell, Antonia L.; Holliday, Holly; Yang, Jessica; Papanicolaou, Michael; Lyons, Ruth J.; Zaratzian, Anaiis; Tayao, Michael; Da Silva, Andrew; Vennin, Claire; Yin, Julia; Dew, Alysha B.; Mcmillan, Paul J.; Goldstein, Leonard D.; Deveson, Ira W.; Croucher, David R.; Samuel, Michael S.; Sim, Hao-Wen; Batten, Marcel; Chantrill, Lorraine; Grimmond, Sean M.; Gill, Anthony J.; Samra, Jaswinder; Evans, Thomas R. Jeffry; Sasaki, Takako; Phan, Tri G.; Swarbrick, Alexander; Sansom, Owen J.; Morton, Jennifer P.; Pajic, Marina; Parker, Benjamin L.; Herrmann, David; Cox, Thomas R.; Timpson, Paul
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse
SCIENCE ADVANCES
IF12.5
2023-04-281
OAAI
Conway, James R. W.; Warren, Sean C.; Lee, Young-Kyung; McCulloch, Andrew T.; Magenau, Astrid; Lee, Victoria; Metcalf, Xanthe L.; Stoehr, Janett; Haigh, Katharina; Abdulkhalek, Lea; Guaman, Cristian S.; Reed, Daniel A.; Murphy, Kendelle J.; Pereira, Brooke A.; Melenec, Pauline; Chambers, Cecilia; Latham, Sharissa L.; Lenthall, Helen; Deenick, Elissa K.; Ma, Yuanqing; Phan, Tri; Lim, Elgene; Joshua, Anthony M.; Walters, Stacey; Grey, Shane T.; Shi, Yan-Chuan; Zhang, Lei; Herzog, Herbert; Croucher, David R.; Philp, Andy; Scheele, Colinda L. G. J.; Herrmann, David; Sansom, Owen J.; Morton, Jennifer P.; Papa, Antonella; Haigh, Jody J.; Nobis, Max; Timpson, Paul
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status

根据Merlin状态，活体成像技术指导FAK介导的胰腺癌精准医学启动

SCIENCE ADVANCES
IF12.5
2021-10-0130
OAAI
Murphy, Kendelle J.; Reed, Daniel A.; Vennin, Claire; Conway, James R. W.; Nobis, Max; Yin, Julia X.; Chambers, Cecilia R.; Pereira, Brooke A.; Lee, Victoria; Filipe, Elysse C.; Trpceski, Michael; Ritchie, Shona; Lucas, Morghan C.; Warren, Sean C.; Skhinas, Joanna N.; Magenau, Astrid; Metcalf, Xanthe L.; Stoehr, Janett; Major, Gretel; Parkin, Ashleigh; Bidanel, Romain; Lyons, Ruth J.; Zaratzian, Anaiis; Tayao, Michael; Da Silva, Andrew; Abdulkhalek, Lea; Gill, Anthony J.; Johns, Amber L.; Biankin, Andrew, V; Samra, Jaswinder; Grimmond, Sean M.; Chou, Angela; Goetz, Jacky G.; Samuel, Michael S.; Lyons, J. Guy; Burgess, Andrew; Caldon, C. Elizabeth; Horvath, Lisa G.; Daly, Roger J.; Gadegaard, Nikolaj; Wang, Yingxiao; Sansom, Owen J.; Morton, Jennifer P.; Cox, Thomas R.; Pajic, Marina; Herrmann, David; Timpson, Paul
Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype
CELL REPORTS
IF6.9
2021-04-0135
OAAI
Valdes-Mora, Fatima; Salomon, Robert; Gloss, Brian Stewart; Law, Andrew Man Kit; Venhuizen, Jeron; Castillo, Lesley; Murphy, Kendelle Joan; Magenau, Astrid; Papanicolaou, Michael; de la Fuente, Laura Rodriguez; Roden, Daniel Lee; Colino-Sanguino, Yolanda; Kikhtyak, Zoya; Farbehi, Nona; Conway, James Ronald William; Sikta, Neblina; Oakes, Samantha Richelle; Cox, Thomas Robert; O'Donoghue, Sean Ignatius; Timpson, Paul; Ormandy, Christopher John; Gallego-Ortega, David
Removing physiological motion from intravital and clinical functional imaging data
ELIFE
IF0
2018-07-0938
OAAI
Warren, Sean C.; Nobis, Max; Magenau, Astrid; Mohammed, Yousuf H.; Herrmann, David; Moran, Imogen; Vennin, Claire; Conway, James R. W.; Melenec, Pauline; Cox, Thomas R.; Wang, Yingxiao; Morton, Jennifer P.; Welch, Heidi C. E.; Strathdee, Douglas; Anderson, Kurt I.; Phan, Tri Giang; Roberts, Michael S.; Timpson, Paul
Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer

活体成像以监测胰腺癌中PI3K通路靶向的移动缺氧区域的治疗反应

CELL REPORTS
IF6.9
2018-06-0162
OAAI
Conway, James R. W.; Warren, Sean C.; Herrmann, David; Murphy, Kendelle J.; Cazet, Aurelie S.; Vennin, Claire; Shearer, Robert F.; Killen, Monica J.; Magenau, Astrid; Melenec, Pauline; Pinese, Mark; Nobis, Max; Zaratzian, Anaiis; Boulghourjian, Alice; Da Silva, Andrew M.; del Monte-Nieto, Gonzalo; Adam, Arne S. A.; Harvey, Richard P.; Haigh, Jody J.; Wang, Yingxiao; Croucher, David R.; Sansom, Owen J.; Pajic, Marina; Caldon, C. Elizabeth; Morton, Jennifer P.; Timpson, Paul
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis

通过ROCK抑制的瞬时组织启动可使胰腺癌的进展，对化学疗法的敏感性和转移脱钩

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2017-04-05211
OAAI
Chin, Venessa T.; Vennin, Claire; Warren, Sean C.; Lucas, Morghan C.; Herrmann, David; Magenau, Astrid; Melenec, Pauline; Walters, Stacey N.; Monte-Nieto, Gonzalo dl; Conway, James R. W.; Nobis, Max; Allam, Amr H.; McCloy, Rachael A.; Currey, Nicola; Pinese, Mark; Boulghourjian, Alice; Zaratzian, Anaiis; Adam, Arne A. S.; Heu, Celine; Nagrial, Adnan M.; Chou, Angela; Steinmann, Angela; Drury, Alison; Froio, Danielle; Giry-Laterriere, Marc; Harris, Nathanial L. E.; Phan, Tri; Jain, Rohit; Weninger, Wolfgang; McGhee, Ewan J.; Whan, Renee; Johns, Amber L.; Samra, Jaswinder S.; Chantrill, Lorraine; Gill, Anthony J.; Kohonen-Corish, Maija; Harvey, Richard P.; Biankin, Andrew V.; Evans, T. R. Jeffry; Anderson, Kurt I.; Grey, Shane T.; Ormandy, Christopher J.; Gallego-Ortega, David; Wang, Yingxiao; Samuel, Michael S.; Sansom, Owen J.; Burgess, Andrew; Cox, Thomas R.; Morton, Jennifer P.; Pajic, Marina; Timpson, Paul
A biosensor mouse to predict the dissociation and spread of pancreatic cancer
CANCER RESEARCH
IF16.6
2017-01-160
PRE
Herrmann, David; Erami, Zahra; Warren, Sean; Nobis, Max; Magenau, Astrid; Lucas, Morghan; Vennin, Claire; McGhee, Ewan J.; Leung, Wilfred; Reischmann, Nadine; Mrowinska, Agata; Schwarz, Juliane P.; Kadir, Shereen; Karim, Saadia A.; Campbell, Andrew D.; Gallego-Ortega, David; Evans, Jeffry; Sansom, Owen J.; Morton, Jennifer P.; Anderson, Kurt I.; Timpson, Paul
Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue
CELL REPORTS
IF6.9
2016-01-0150
OAAI
Erami, Zahra; Herrmann, David; Warren, Sean C.; Nobis, Max; McGhee, Ewan J.; Lucas, Morghan C.; Leung, Wilfred; Reischmann, Nadine; Mrowinska, Agata; Schwarz, Juliane P.; Kadir, Shereen; Conway, James R. W.; Vennin, Claire; Karim, Saadia A.; Campbell, Andrew D.; Gallego-Ortega, David; Magenau, Astrid; Murphy, Kendelle J.; Ridgway, Rachel A.; Law, Andrew M.; Walters, Stacey N.; Grey, Shane T.; Croucher, David R.; Zhang, Lei; Herzog, Herbert; Hardeman, Edna C.; Gunning, Peter W.; Ormandy, Christopher J.; Evans, T. R. Jeffry; Strathdee, Douglas; Sansom, Owen J.; Morton, Jennifer P.; Anderson, Kurt I.; Timpson, Paul
A Negative Regulatory Mechanism Involving 14-3-3ζ Limits Signaling Downstream of ROCK to Regulate Tissue Stiffness in Epidermal Homeostasis
DEVELOPMENTAL CELL
IF8.7
2015-12-0125
OA
Kular, Jasreen; Scheer, Kaitlin G.; Pyne, Natasha T.; Allam, Amr H.; Pollard, Anthony N.; Magenau, Astrid; Wright, Rebecca L.; Kolesnikoff, Natasha; Moretti, Paul A.; Wullkopf, Lena; Stomski, Frank C.; Cowin, Allison J.; Woodcock, Joanna M.; Grimbaldeston, Michele A.; Pitson, Stuart M.; Timpson, Paul; Ramshaw, Hayley S.; Lopez, Angel F.; Samuel, Michael S.

研究方向

暂未获取到该数据
K
Katharina Gaus
H 指数:68论文数:318被引数:1.5万
P
Paul Timpson
H 指数:70论文数:510被引数:1.4万
D
David Herrmann
H 指数:32论文数:319被引数:4,215
J
Jennifer P. Morton
H 指数:77论文数:391被引数:2.4万
M
Max Nobis
H 指数:31论文数:139被引数:3,223
D
Dylan M. Owen
H 指数:45论文数:182被引数:6,996
C
Claire Vennin
H 指数:28论文数:152被引数:2,987
S
Sean Warren
H 指数:27论文数:75被引数:3,228
J
J. Justin Gooding
H 指数:100论文数:910被引数:4.1万
J
James R. W. Conway
H 指数:33论文数:73被引数:8,663