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D

David Herrmann

Garvan Institute of Medical Research and Kinghorn Cancer Centre
H指数:32
被引数:4,186

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A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer

一种一流的泛赖氨酰氧化酶抑制剂可削弱胰腺癌的基质重塑并增强吉西他滨反应和生存率

NATURE CANCER
IF28.5
2023-08-2823
OAAI
Chitty, Jessica L.; Yam, Michelle; Perryman, Lara; Parker, Amelia L.; Skhinas, Joanna N.; Setargew, Yordanos F. I.; Mok, Ellie T. Y.; Tran, Emmi; Grant, Rhiannon D.; Latham, Sharissa L.; Pereira, Brooke A.; Ritchie, Shona C.; Murphy, Kendelle J.; Trpceski, Michael; Findlay, Alison D.; Melenec, Pauline; Filipe, Elysse C.; Nadalini, Audrey; Velayuthar, Sipiththa; Major, Gretel; Wyllie, Kaitlin; Papanicolaou, Michael; Ratnaseelan, Shivanjali; Phillips, Phoebe A.; Sharbeen, George; Youkhana, Janet; Russo, Alice; Blackwell, Antonia; Hastings, Jordan F.; Lucas, Morghan C.; Chambers, Cecilia R.; Reed, Daniel A.; Stoehr, Janett; Vennin, Claire; Pidsley, Ruth; Zaratzian, Anaiis; Da Silva, Andrew M.; Tayao, Michael; Charlton, Brett; Herrmann, David; Nobis, Max; Clark, Susan J.; Biankin, Andrew V.; Johns, Amber L.; Croucher, David R.; Nagrial, Adnan; Gill, Anthony J.; Grimmond, Sean M.; Pajic, Marina; Timpson, Paul; Jarolimek, Wolfgang; Cox, Thomas R.
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse
SCIENCE ADVANCES
IF12.5
2023-04-281
OAAI
Conway, James R. W.; Warren, Sean C.; Lee, Young-Kyung; McCulloch, Andrew T.; Magenau, Astrid; Lee, Victoria; Metcalf, Xanthe L.; Stoehr, Janett; Haigh, Katharina; Abdulkhalek, Lea; Guaman, Cristian S.; Reed, Daniel A.; Murphy, Kendelle J.; Pereira, Brooke A.; Melenec, Pauline; Chambers, Cecilia; Latham, Sharissa L.; Lenthall, Helen; Deenick, Elissa K.; Ma, Yuanqing; Phan, Tri; Lim, Elgene; Joshua, Anthony M.; Walters, Stacey; Grey, Shane T.; Shi, Yan-Chuan; Zhang, Lei; Herzog, Herbert; Croucher, David R.; Philp, Andy; Scheele, Colinda L. G. J.; Herrmann, David; Sansom, Owen J.; Morton, Jennifer P.; Papa, Antonella; Haigh, Jody J.; Nobis, Max; Timpson, Paul
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis

乳腺肿瘤微环境的时间分布显示胶原蛋白XII是转移的驱动因素

NATURE COMMUNICATIONS
IF15.7
2022-08-0697
OAAI
Papanicolaou, Michael; Parker, Amelia L.; Yam, Michelle; Filipe, Elysse C.; Wu, Sunny Z.; Chitty, Jessica L.; Wyllie, Kaitlin; Tran, Emmi; Mok, Ellie; Nadalini, Audrey; Skhinas, Joanna N.; Lucas, Morghan C.; Herrmann, David; Nobis, Max; Pereira, Brooke A.; Law, Andrew M. K.; Castillo, Lesley; Murphy, Kendelle J.; Zaratzian, Anaiis; Hastings, Jordan F.; Croucher, David R.; Lim, Elgene; Oliver, Brian G.; Mora, Fatima Valdes; Parker, Benjamin L.; Gallego-Ortega, David; Swarbrick, Alexander; O'Toole, Sandra; Timpson, Paul; Cox, Thomas R.
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status

根据Merlin状态，活体成像技术指导FAK介导的胰腺癌精准医学启动

SCIENCE ADVANCES
IF12.5
2021-10-0130
OAAI
Murphy, Kendelle J.; Reed, Daniel A.; Vennin, Claire; Conway, James R. W.; Nobis, Max; Yin, Julia X.; Chambers, Cecilia R.; Pereira, Brooke A.; Lee, Victoria; Filipe, Elysse C.; Trpceski, Michael; Ritchie, Shona; Lucas, Morghan C.; Warren, Sean C.; Skhinas, Joanna N.; Magenau, Astrid; Metcalf, Xanthe L.; Stoehr, Janett; Major, Gretel; Parkin, Ashleigh; Bidanel, Romain; Lyons, Ruth J.; Zaratzian, Anaiis; Tayao, Michael; Da Silva, Andrew; Abdulkhalek, Lea; Gill, Anthony J.; Johns, Amber L.; Biankin, Andrew, V; Samra, Jaswinder; Grimmond, Sean M.; Chou, Angela; Goetz, Jacky G.; Samuel, Michael S.; Lyons, J. Guy; Burgess, Andrew; Caldon, C. Elizabeth; Horvath, Lisa G.; Daly, Roger J.; Gadegaard, Nikolaj; Wang, Yingxiao; Sansom, Owen J.; Morton, Jennifer P.; Cox, Thomas R.; Pajic, Marina; Herrmann, David; Timpson, Paul
Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
CELL REPORTS
IF6.9
2021-09-0117
OAAI
Floerchinger, Alessia; Murphy, Kendelle J.; Latham, Sharissa L.; Warren, Sean C.; McCulloch, Andrew T.; Lee, Young-Kyung; Stoehr, Janett; Melenec, Pauline; Guaman, Cris S.; Metcalf, Xanthe L.; Lee, Victoria; Zaratzian, Anaiis; Da Silva, Andrew; Tayao, Michael; Rolo, Sonia; Phimmachanh, Monica; Sultani, Ghazal; McDonald, Laura; Mason, Susan M.; Ferrari, Nicola; Ooms, Lisa M.; Johnsson, Anna-Karin E.; Spence, Heather J.; Olson, Michael F.; Machesky, Laura M.; Sansom, Owen J.; Morton, Jennifer P.; Mitchell, Christina A.; Samuel, Michael S.; Croucher, David R.; Welch, Heidi C. E.; Blyth, Karen; Caldon, C. Elizabeth; Herrmann, David; Anderson, Kurt, I; Timpson, Paul; Nobis, Max
Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis
NATURE COMMUNICATIONS
IF15.7
2021-06-24107
OAAI
Samuel, Monisha; Fonseka, Pamali; Sanwlani, Rahul; Gangoda, Lahiru; Chee, Sing Ho; Keerthikumar, Shivakumar; Spurling, Alex; Chitti, Sai V.; Zanker, Damien; Ang, Ching-Seng; Atukorala, Ishara; Kang, Taeyoung; Shahi, Sanjay; Marzan, Akbar L.; Nedeva, Christina; Vennin, Claire; Lucas, Morghan C.; Cheng, Lesley; Herrmann, David; Pathan, Mohashin; Chisanga, David; Warren, Sean C.; Zhao, Kening; Abraham, Nidhi; Anand, Sushma; Boukouris, Stephanie; Adda, Christopher G.; Jiang, Lanzhou; Shekhar, Tanmay M.; Baschuk, Nikola; Hawkins, Christine J.; Johnston, Amelia J.; Orian, Jacqueline Monique; Hoogenraad, Nicholas J.; Poon, Ivan K.; Hill, Andrew F.; Jois, Markandeya; Timpson, Paul; Parker, Belinda S.; Mathivanan, Suresh
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

由胰腺癌细胞p53-status驱动的CAF层次结构通过perlecan创造了一个促转移和化学抗性的环境

NATURE COMMUNICATIONS
IF15.7
2019-08-12184
OAAI
Vennin, Claire; Melenec, Pauline; Rouet, Romain; Nobis, Max; Cazet, Aurelie S.; Murphy, Kendelle J.; Herrmann, David; Reed, Daniel A.; Lucas, Morghan C.; Warren, Sean C.; Elgundi, Zehra; Pinese, Mark; Kalna, Gabriella; Roden, Daniel; Samuel, Monisha; Zaratzian, Anaiis; Grey, Shane T.; Da Silva, Andrew; Leung, Wilfred; Mathivanan, Suresh; Wang, Yingxiao; Braithwaite, Anthony W.; Christ, Daniel; Benda, Ales; Parkin, Ashleigh; Phillips, Phoebe A.; Whitelock, John M.; Gill, Anthony J.; Sansom, Owen J.; Croucher, David R.; Parker, Benjamin L.; Pajic, Marina; Morton, Jennifer P.; Cox, Thomas R.; Timpson, Paul; Johns, Amber L.; Chantrill, Lorraine A.; Chou, Angela; Steinmann, Angela; Arshi, Mehreen; Dwarte, Tanya; Froio, Danielle; Pereira, Brooke; Ritchie, Shona; Chambers, Cecilia R.; Metcalf, Xanthe; Waddell, Nicola; Pearson, John, V; Patch, Ann-Marie; Nones, Katia; Newell, Felicity; Mukhopadhyay, Pamela; Addala, Venkateswar; Kazakoff, Stephen; Holmes, Oliver; Leonard, Conrad; Wood, Scott; Grimmond, Sean M.; Hofmann, Oliver; Christ, Angelika; Bruxner, Tim; Samra, Jaswinder S.; Pavlakis, Nick; High, Hilda A.; Asghari, Ray; Merrett, Neil D.; Pavey, Darren; Das, Amitabha; Cosman, Peter H.; Ismail, Kasim; O'Connnor, Chelsie; Stoita, Alina; Williams, David; Spigellman, Allan; Lam, Vincent W.; McLeod, Duncan; Kirk, Judy; Kench, James G.; Grimison, Peter; Cooper, Caroline L.; Sandroussi, Charbel; Goodwin, Annabel; Mead, R. Scott; Tucker, Katherine; Andrews, Lesley; Texler, Michael; Forest, Cindy; Epari, Krishna P.; Ballal, Mo; Fletcher, David R.; Mukhedkar, Sanjay; Zeps, Nikolajs; Beilin, Maria; Feeney, Kynan; Nguyen, Nan Q.; Ruszkiewicz, Andrew R.; Worthley, Chris; Chen, John; Brooke-Smith, Mark E.; Papangelis, Virginia; Clouston, Andrew D.; Barbour, Andrew P.; O'Rourke, Thomas J.; Fawcett, Jonathan W.; Slater, Kellee; Hatzifotis, Michael; Hodgkinson, Peter; Nikfarjam, Mehrdad; Eshleman, James R.; Hruban, Ralph H.; Wolfgang, Christopher L.; Lawlor, Rita T.; Beghelli, Stefania; Corbo, Vincenzo; Scardoni, Maria; Bassi, Claudio; Biankin, Andrew, V; Dixon, Judith; Jamieson, Nigel B.; Chang, David K.
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer

靶向基质重塑和癌症干细胞可塑性克服了三阴性乳腺癌的化学抗性

NATURE COMMUNICATIONS
IF15.7
2018-07-24326
OAAI
Cazet, Aurelie S.; Hui, Mun N.; Elsworth, Benjamin L.; Wu, Sunny Z.; Roden, Daniel; Chan, Chia-Ling; Skhinas, Joanna N.; Collot, Raphael; Yang, Jessica; Harvey, Kate; Johan, M. Zahied; Cooper, Caroline; Nair, Radhika; Herrmann, David; McFarland, Andrea; Deng, Niantao; Ruiz-Borrego, Manuel; Rojo, Federico; Trigo, Jose M.; Bezares, Susana; Caballero, Rosalia; Lim, Elgene; Timpson, Paul; O'Toole, Sandra; Watkins, D. Neil; Cox, Thomas R.; Samuel, Michael S.; Martin, Miguel; Swarbrick, Alexander
Removing physiological motion from intravital and clinical functional imaging data
ELIFE
IF0
2018-07-0938
OAAI
Warren, Sean C.; Nobis, Max; Magenau, Astrid; Mohammed, Yousuf H.; Herrmann, David; Moran, Imogen; Vennin, Claire; Conway, James R. W.; Melenec, Pauline; Cox, Thomas R.; Wang, Yingxiao; Morton, Jennifer P.; Welch, Heidi C. E.; Strathdee, Douglas; Anderson, Kurt I.; Phan, Tri Giang; Roberts, Michael S.; Timpson, Paul

研究方向

暂未获取到该数据
P
Paul Timpson
H 指数:70论文数:510被引数:1.4万
M
Max Nobis
H 指数:31论文数:139被引数:3,195
S
Sean Warren
H 指数:27论文数:75被引数:3,217
J
Jennifer P. Morton
H 指数:77论文数:391被引数:2.4万
C
Claire Vennin
H 指数:28论文数:152被引数:2,969
K
Kendelle J. Murphy
H 指数:19论文数:45被引数:2,161
M
Morghan C. Lucas
H 指数:25论文数:67被引数:3,437
A
Astrid Magenau
H 指数:31论文数:66被引数:3,818
J
James R. W. Conway
H 指数:33论文数:73被引数:8,609
T
Thomas R. Cox
H 指数:49论文数:350被引数:1.5万