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S

Sean Warren

imperial college london
H指数:27
被引数:3,228

个人简介

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教育背景

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工作经历

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荣誉奖项

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Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response

暂时分辨的蛋白质组学将nidogen-2鉴定为胰腺癌的共靶标，其调节纤维化和治疗反应

SCIENCE ADVANCES
IF12.5
2024-07-052
OAAI
Pereira, Brooke A.; Ritchie, Shona; Chambers, Cecilia R.; Gordon, Katie A.; Magenau, Astrid; Murphy, Kendelle J.; Nobis, Max; Tyma, Victoria M.; Liew, Ying Fei; Lucas, Morghan C.; Naeini, Marjan M.; Barkauskas, Deborah S.; Chacon-Fajardo, Diego; Howell, Anna E.; Parker, Amelia L.; Warren, Sean C.; Reed, Daniel A.; Lee, Victoria; Metcalf, Xanthe L.; Lee, Young Kyung; O'Regan, Luke P.; Zhu, Jessie; Trpceski, Michael; Fontaine, Angela R. M.; Stoehr, Janett; Rouet, Romain; Lin, Xufeng; Chitty, Jessica L.; Porazinski, Sean; Wu, Sunny Z.; Filipe, Elysse C.; Cadell, Antonia L.; Holliday, Holly; Yang, Jessica; Papanicolaou, Michael; Lyons, Ruth J.; Zaratzian, Anaiis; Tayao, Michael; Da Silva, Andrew; Vennin, Claire; Yin, Julia; Dew, Alysha B.; Mcmillan, Paul J.; Goldstein, Leonard D.; Deveson, Ira W.; Croucher, David R.; Samuel, Michael S.; Sim, Hao-Wen; Batten, Marcel; Chantrill, Lorraine; Grimmond, Sean M.; Gill, Anthony J.; Samra, Jaswinder; Evans, Thomas R. Jeffry; Sasaki, Takako; Phan, Tri G.; Swarbrick, Alexander; Sansom, Owen J.; Morton, Jennifer P.; Pajic, Marina; Parker, Benjamin L.; Herrmann, David; Cox, Thomas R.; Timpson, Paul
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse
SCIENCE ADVANCES
IF12.5
2023-04-281
OAAI
Conway, James R. W.; Warren, Sean C.; Lee, Young-Kyung; McCulloch, Andrew T.; Magenau, Astrid; Lee, Victoria; Metcalf, Xanthe L.; Stoehr, Janett; Haigh, Katharina; Abdulkhalek, Lea; Guaman, Cristian S.; Reed, Daniel A.; Murphy, Kendelle J.; Pereira, Brooke A.; Melenec, Pauline; Chambers, Cecilia; Latham, Sharissa L.; Lenthall, Helen; Deenick, Elissa K.; Ma, Yuanqing; Phan, Tri; Lim, Elgene; Joshua, Anthony M.; Walters, Stacey; Grey, Shane T.; Shi, Yan-Chuan; Zhang, Lei; Herzog, Herbert; Croucher, David R.; Philp, Andy; Scheele, Colinda L. G. J.; Herrmann, David; Sansom, Owen J.; Morton, Jennifer P.; Papa, Antonella; Haigh, Jody J.; Nobis, Max; Timpson, Paul
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status

根据Merlin状态，活体成像技术指导FAK介导的胰腺癌精准医学启动

SCIENCE ADVANCES
IF12.5
2021-10-0130
OAAI
Murphy, Kendelle J.; Reed, Daniel A.; Vennin, Claire; Conway, James R. W.; Nobis, Max; Yin, Julia X.; Chambers, Cecilia R.; Pereira, Brooke A.; Lee, Victoria; Filipe, Elysse C.; Trpceski, Michael; Ritchie, Shona; Lucas, Morghan C.; Warren, Sean C.; Skhinas, Joanna N.; Magenau, Astrid; Metcalf, Xanthe L.; Stoehr, Janett; Major, Gretel; Parkin, Ashleigh; Bidanel, Romain; Lyons, Ruth J.; Zaratzian, Anaiis; Tayao, Michael; Da Silva, Andrew; Abdulkhalek, Lea; Gill, Anthony J.; Johns, Amber L.; Biankin, Andrew, V; Samra, Jaswinder; Grimmond, Sean M.; Chou, Angela; Goetz, Jacky G.; Samuel, Michael S.; Lyons, J. Guy; Burgess, Andrew; Caldon, C. Elizabeth; Horvath, Lisa G.; Daly, Roger J.; Gadegaard, Nikolaj; Wang, Yingxiao; Sansom, Owen J.; Morton, Jennifer P.; Cox, Thomas R.; Pajic, Marina; Herrmann, David; Timpson, Paul
Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
CELL REPORTS
IF6.9
2021-09-0117
OAAI
Floerchinger, Alessia; Murphy, Kendelle J.; Latham, Sharissa L.; Warren, Sean C.; McCulloch, Andrew T.; Lee, Young-Kyung; Stoehr, Janett; Melenec, Pauline; Guaman, Cris S.; Metcalf, Xanthe L.; Lee, Victoria; Zaratzian, Anaiis; Da Silva, Andrew; Tayao, Michael; Rolo, Sonia; Phimmachanh, Monica; Sultani, Ghazal; McDonald, Laura; Mason, Susan M.; Ferrari, Nicola; Ooms, Lisa M.; Johnsson, Anna-Karin E.; Spence, Heather J.; Olson, Michael F.; Machesky, Laura M.; Sansom, Owen J.; Morton, Jennifer P.; Mitchell, Christina A.; Samuel, Michael S.; Croucher, David R.; Welch, Heidi C. E.; Blyth, Karen; Caldon, C. Elizabeth; Herrmann, David; Anderson, Kurt, I; Timpson, Paul; Nobis, Max
Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis
NATURE COMMUNICATIONS
IF15.7
2021-06-24107
OAAI
Samuel, Monisha; Fonseka, Pamali; Sanwlani, Rahul; Gangoda, Lahiru; Chee, Sing Ho; Keerthikumar, Shivakumar; Spurling, Alex; Chitti, Sai V.; Zanker, Damien; Ang, Ching-Seng; Atukorala, Ishara; Kang, Taeyoung; Shahi, Sanjay; Marzan, Akbar L.; Nedeva, Christina; Vennin, Claire; Lucas, Morghan C.; Cheng, Lesley; Herrmann, David; Pathan, Mohashin; Chisanga, David; Warren, Sean C.; Zhao, Kening; Abraham, Nidhi; Anand, Sushma; Boukouris, Stephanie; Adda, Christopher G.; Jiang, Lanzhou; Shekhar, Tanmay M.; Baschuk, Nikola; Hawkins, Christine J.; Johnston, Amelia J.; Orian, Jacqueline Monique; Hoogenraad, Nicholas J.; Poon, Ivan K.; Hill, Andrew F.; Jois, Markandeya; Timpson, Paul; Parker, Belinda S.; Mathivanan, Suresh
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

由胰腺癌细胞p53-status驱动的CAF层次结构通过perlecan创造了一个促转移和化学抗性的环境

NATURE COMMUNICATIONS
IF15.7
2019-08-12184
OAAI
Vennin, Claire; Melenec, Pauline; Rouet, Romain; Nobis, Max; Cazet, Aurelie S.; Murphy, Kendelle J.; Herrmann, David; Reed, Daniel A.; Lucas, Morghan C.; Warren, Sean C.; Elgundi, Zehra; Pinese, Mark; Kalna, Gabriella; Roden, Daniel; Samuel, Monisha; Zaratzian, Anaiis; Grey, Shane T.; Da Silva, Andrew; Leung, Wilfred; Mathivanan, Suresh; Wang, Yingxiao; Braithwaite, Anthony W.; Christ, Daniel; Benda, Ales; Parkin, Ashleigh; Phillips, Phoebe A.; Whitelock, John M.; Gill, Anthony J.; Sansom, Owen J.; Croucher, David R.; Parker, Benjamin L.; Pajic, Marina; Morton, Jennifer P.; Cox, Thomas R.; Timpson, Paul; Johns, Amber L.; Chantrill, Lorraine A.; Chou, Angela; Steinmann, Angela; Arshi, Mehreen; Dwarte, Tanya; Froio, Danielle; Pereira, Brooke; Ritchie, Shona; Chambers, Cecilia R.; Metcalf, Xanthe; Waddell, Nicola; Pearson, John, V; Patch, Ann-Marie; Nones, Katia; Newell, Felicity; Mukhopadhyay, Pamela; Addala, Venkateswar; Kazakoff, Stephen; Holmes, Oliver; Leonard, Conrad; Wood, Scott; Grimmond, Sean M.; Hofmann, Oliver; Christ, Angelika; Bruxner, Tim; Samra, Jaswinder S.; Pavlakis, Nick; High, Hilda A.; Asghari, Ray; Merrett, Neil D.; Pavey, Darren; Das, Amitabha; Cosman, Peter H.; Ismail, Kasim; O'Connnor, Chelsie; Stoita, Alina; Williams, David; Spigellman, Allan; Lam, Vincent W.; McLeod, Duncan; Kirk, Judy; Kench, James G.; Grimison, Peter; Cooper, Caroline L.; Sandroussi, Charbel; Goodwin, Annabel; Mead, R. Scott; Tucker, Katherine; Andrews, Lesley; Texler, Michael; Forest, Cindy; Epari, Krishna P.; Ballal, Mo; Fletcher, David R.; Mukhedkar, Sanjay; Zeps, Nikolajs; Beilin, Maria; Feeney, Kynan; Nguyen, Nan Q.; Ruszkiewicz, Andrew R.; Worthley, Chris; Chen, John; Brooke-Smith, Mark E.; Papangelis, Virginia; Clouston, Andrew D.; Barbour, Andrew P.; O'Rourke, Thomas J.; Fawcett, Jonathan W.; Slater, Kellee; Hatzifotis, Michael; Hodgkinson, Peter; Nikfarjam, Mehrdad; Eshleman, James R.; Hruban, Ralph H.; Wolfgang, Christopher L.; Lawlor, Rita T.; Beghelli, Stefania; Corbo, Vincenzo; Scardoni, Maria; Bassi, Claudio; Biankin, Andrew, V; Dixon, Judith; Jamieson, Nigel B.; Chang, David K.
Removing physiological motion from intravital and clinical functional imaging data
ELIFE
IF0
2018-07-0938
OAAI
Warren, Sean C.; Nobis, Max; Magenau, Astrid; Mohammed, Yousuf H.; Herrmann, David; Moran, Imogen; Vennin, Claire; Conway, James R. W.; Melenec, Pauline; Cox, Thomas R.; Wang, Yingxiao; Morton, Jennifer P.; Welch, Heidi C. E.; Strathdee, Douglas; Anderson, Kurt I.; Phan, Tri Giang; Roberts, Michael S.; Timpson, Paul
Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer

活体成像以监测胰腺癌中PI3K通路靶向的移动缺氧区域的治疗反应

CELL REPORTS
IF6.9
2018-06-0162
OAAI
Conway, James R. W.; Warren, Sean C.; Herrmann, David; Murphy, Kendelle J.; Cazet, Aurelie S.; Vennin, Claire; Shearer, Robert F.; Killen, Monica J.; Magenau, Astrid; Melenec, Pauline; Pinese, Mark; Nobis, Max; Zaratzian, Anaiis; Boulghourjian, Alice; Da Silva, Andrew M.; del Monte-Nieto, Gonzalo; Adam, Arne S. A.; Harvey, Richard P.; Haigh, Jody J.; Wang, Yingxiao; Croucher, David R.; Sansom, Owen J.; Pajic, Marina; Caldon, C. Elizabeth; Morton, Jennifer P.; Timpson, Paul
Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology

来自替代胶原来源的三维器官型基质作为细胞生物学的临床前模型

SCIENTIFIC REPORTS
IF3.9
2017-12-0423
OAAI
Conway, James R. W.; Vennin, Claire; Cazet, Aurelie S.; Herrmann, David; Murphy, Kendelle J.; Warren, Sean C.; Wullkopf, Lena; Boulghourjian, Alice; Zaratzian, Anaiis; Da Silva, Andrew M.; Pajic, Marina; Morton, Jennifer P.; Cox, Thomas R.; Timpson, Paul
A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts

RhoA-FRET生物传感器小鼠，用于在正常组织稳态和疾病背景下进行活体成像

CELL REPORTS
IF6.9
2017-10-0176
OAAI
Nobis, Max; Herrmann, David; Warren, Sean C.; Kadir, Shereen; Leung, Wilfred; Killen, Monica; Stevenson, David; Lucas, Morghan C.; Reischmann, Nadine; Vennin, Claire; Conway, James R. W.; Boulghourjian, Alice; Zaratzian, Anaiis; Law, Andrew M.; Gallego-Ortega, David; Ormandy, Christopher J.; Walters, Stacey N.; Grey, Shane T.; Bailey, Jacqueline; Chtanova, Tatyana; Quinn, Julian M. W.; Baldock, Paul A.; Croucher, Peter I.; Schwarz, Juliane P.; Mrowinska, Agata; Zhang, Lei; Herzog, Herbert; Masedunskas, Andrius; Hardeman, Edna C.; Gunning, Peter W.; del Monte-Nieto, Gonzalo; Harvey, Richard P.; Samuel, Michael S.; Pajic, Marina; McGhee, Ewan J.; Johnsson, Anna-Karin E.; Sansom, Owen J.; Welch, Heidi C. E.; Morton, Jennifer P.; Strathdee, Douglas; Anderson, Kurt I.; Timpson, Paul
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis

通过ROCK抑制的瞬时组织启动可使胰腺癌的进展，对化学疗法的敏感性和转移脱钩

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2017-04-05211
OAAI
Chin, Venessa T.; Vennin, Claire; Warren, Sean C.; Lucas, Morghan C.; Herrmann, David; Magenau, Astrid; Melenec, Pauline; Walters, Stacey N.; Monte-Nieto, Gonzalo dl; Conway, James R. W.; Nobis, Max; Allam, Amr H.; McCloy, Rachael A.; Currey, Nicola; Pinese, Mark; Boulghourjian, Alice; Zaratzian, Anaiis; Adam, Arne A. S.; Heu, Celine; Nagrial, Adnan M.; Chou, Angela; Steinmann, Angela; Drury, Alison; Froio, Danielle; Giry-Laterriere, Marc; Harris, Nathanial L. E.; Phan, Tri; Jain, Rohit; Weninger, Wolfgang; McGhee, Ewan J.; Whan, Renee; Johns, Amber L.; Samra, Jaswinder S.; Chantrill, Lorraine; Gill, Anthony J.; Kohonen-Corish, Maija; Harvey, Richard P.; Biankin, Andrew V.; Evans, T. R. Jeffry; Anderson, Kurt I.; Grey, Shane T.; Ormandy, Christopher J.; Gallego-Ortega, David; Wang, Yingxiao; Samuel, Michael S.; Sansom, Owen J.; Burgess, Andrew; Cox, Thomas R.; Morton, Jennifer P.; Pajic, Marina; Timpson, Paul
A biosensor mouse to predict the dissociation and spread of pancreatic cancer
CANCER RESEARCH
IF16.6
2017-01-160
PRE
Herrmann, David; Erami, Zahra; Warren, Sean; Nobis, Max; Magenau, Astrid; Lucas, Morghan; Vennin, Claire; McGhee, Ewan J.; Leung, Wilfred; Reischmann, Nadine; Mrowinska, Agata; Schwarz, Juliane P.; Kadir, Shereen; Karim, Saadia A.; Campbell, Andrew D.; Gallego-Ortega, David; Evans, Jeffry; Sansom, Owen J.; Morton, Jennifer P.; Anderson, Kurt I.; Timpson, Paul

研究方向

暂未获取到该数据
P
Paul Timpson
H 指数:70论文数:510被引数:1.4万
D
David Herrmann
H 指数:32论文数:319被引数:4,215
J
Jennifer P. Morton
H 指数:77论文数:391被引数:2.4万
M
Max Nobis
H 指数:31论文数:139被引数:3,223
O
Owen J. Sansom
H 指数:113论文数:1,190被引数:5.1万
M
Morghan C. Lucas
H 指数:25论文数:67被引数:3,467
C
Claire Vennin
H 指数:28论文数:152被引数:2,987
K
Kendelle J. Murphy
H 指数:19论文数:45被引数:2,184
J
James R. W. Conway
H 指数:33论文数:73被引数:8,660
A
Astrid Magenau
H 指数:31论文数:66被引数:3,827