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J

James R. W. Conway

University of Helsinki
H指数:33
被引数:8,609

个人简介

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工作经历

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荣誉奖项

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ADAM10 Knockout from Human Glioblastoma and Colon Cancer Cells Modulates Diverse Signalling Networks and Inhibits Tumour Growth In Vivo

ADAM10基因敲除的人胶质母细胞瘤和结癌细胞可调节多种信号网络并抑制体内肿瘤生长

International Journal of Molecular Sciences 2025, Vol. 26, Page 10684
IF4.9
2025-11-030
OAAI
Hengkang Yan; Sakshi Arora; Linda Hii; Carmen Llerena; Mary E. Vail; Amr Allam; James R. W. Conway; Joel R. Steele; Han-Chung Lee; Ralf B. Schittenhelm; Andrew M. Scott; Peter W. Janes
Cell-penetrant peptides as novel inhibitors of the interaction of coatomer protein COPB2/RACK2 with protein kinase Cε and cargo proteins

细胞穿透肽作为新型抑制剂，可抑制coatamer蛋白COPB2/RACK2与蛋白激酶Cε及货物蛋白的相互作用

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
IF0
2025-10-180
OAAI
Abisola A. Olushola-Siedoks; Lewin Small; Kathryn J. Fincham; Dorothy C.C. Wai; Dhruv Monteiro; James R.W. Conway; Antonia Cadell; Benjamin J. Parker; David R. Croucher; Carsten Schmitz-Peiffer; Raymond S. Norton
SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers

SHANK3耗竭导致KRAS突变癌症中ERK信号过量和细胞死亡

NATURE COMMUNICATIONS
IF15.7
2024-09-122
OAAI
Lilja, Johanna; Kaivola, Jasmin; Conway, James R. W.; Vuorio, Joni; Parkkola, Hanna; Roivas, Pekka; Dibus, Michal; Chastney, Megan R.; Varila, Taru; Jacquemet, Guillaume; Peuhu, Emilia; Wang, Emily; Pentikainen, Ulla; Posada, Itziar Martinez D.; Hamidi, Hellyeh; Najumudeen, Arafath K.; Sansom, Owen J.; Barsukov, Igor L.; Abankwa, Daniel; Vattulainen, Ilpo; Salmi, Marko; Ivaska, Johanna
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse
SCIENCE ADVANCES
IF12.5
2023-04-281
OAAI
Conway, James R. W.; Warren, Sean C.; Lee, Young-Kyung; McCulloch, Andrew T.; Magenau, Astrid; Lee, Victoria; Metcalf, Xanthe L.; Stoehr, Janett; Haigh, Katharina; Abdulkhalek, Lea; Guaman, Cristian S.; Reed, Daniel A.; Murphy, Kendelle J.; Pereira, Brooke A.; Melenec, Pauline; Chambers, Cecilia; Latham, Sharissa L.; Lenthall, Helen; Deenick, Elissa K.; Ma, Yuanqing; Phan, Tri; Lim, Elgene; Joshua, Anthony M.; Walters, Stacey; Grey, Shane T.; Shi, Yan-Chuan; Zhang, Lei; Herzog, Herbert; Croucher, David R.; Philp, Andy; Scheele, Colinda L. G. J.; Herrmann, David; Sansom, Owen J.; Morton, Jennifer P.; Papa, Antonella; Haigh, Jody J.; Nobis, Max; Timpson, Paul
Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis (vol 23, pg 1073, 2021)
NATURE CELL BIOLOGY
IF19.1
2022-08-290
OA
Moreno-Layseca, Paulina; Jantti, Niklas Z.; Godbole, Rashmi; Sommer, Christian; Jacquemet, Guillaume; Al-Akhrass, Hussein; Conway, James R. W.; Kronqvist, Pauliina; Kallionpaa, Roosa E.; Oliveira-Ferrer, Leticia; Cervero, Pasquale; Linder, Stefan; Aepfelbacher, Martin; Zauber, Henrik; Rae, James; Parton, Robert G.; Disanza, Andrea; Scita, Giorgio; Mayor, Satyajit; Selbach, Matthias; Veltel, Stefan; Ivaska, Johanna
Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis
NATURE CELL BIOLOGY
IF19.1
2021-10-0636
OA
Moreno-Layseca, Paulina; Jantti, Niklas Z.; Godbole, Rashmi; Sommer, Christian; Jacquemet, Guillaume; Al-Akhrass, Hussein; Conway, James R. W.; Kronqvist, Pauliina; Kallionpaa, Roosa E.; Oliveira-Ferrer, Leticia; Cervero, Pasquale; Linder, Stefan; Aepfelbacher, Martin; Zauber, Henrik; Rae, James; Parton, Robert G.; Disanza, Andrea; Scita, Giorgio; Mayor, Satyajit; Selbach, Matthias; Veltel, Stefan; Ivaska, Johanna
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status

根据Merlin状态，活体成像技术指导FAK介导的胰腺癌精准医学启动

SCIENCE ADVANCES
IF12.5
2021-10-0130
OAAI
Murphy, Kendelle J.; Reed, Daniel A.; Vennin, Claire; Conway, James R. W.; Nobis, Max; Yin, Julia X.; Chambers, Cecilia R.; Pereira, Brooke A.; Lee, Victoria; Filipe, Elysse C.; Trpceski, Michael; Ritchie, Shona; Lucas, Morghan C.; Warren, Sean C.; Skhinas, Joanna N.; Magenau, Astrid; Metcalf, Xanthe L.; Stoehr, Janett; Major, Gretel; Parkin, Ashleigh; Bidanel, Romain; Lyons, Ruth J.; Zaratzian, Anaiis; Tayao, Michael; Da Silva, Andrew; Abdulkhalek, Lea; Gill, Anthony J.; Johns, Amber L.; Biankin, Andrew, V; Samra, Jaswinder; Grimmond, Sean M.; Chou, Angela; Goetz, Jacky G.; Samuel, Michael S.; Lyons, J. Guy; Burgess, Andrew; Caldon, C. Elizabeth; Horvath, Lisa G.; Daly, Roger J.; Gadegaard, Nikolaj; Wang, Yingxiao; Sansom, Owen J.; Morton, Jennifer P.; Cox, Thomas R.; Pajic, Marina; Herrmann, David; Timpson, Paul
Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype
CELL REPORTS
IF6.9
2021-04-0135
OAAI
Valdes-Mora, Fatima; Salomon, Robert; Gloss, Brian Stewart; Law, Andrew Man Kit; Venhuizen, Jeron; Castillo, Lesley; Murphy, Kendelle Joan; Magenau, Astrid; Papanicolaou, Michael; de la Fuente, Laura Rodriguez; Roden, Daniel Lee; Colino-Sanguino, Yolanda; Kikhtyak, Zoya; Farbehi, Nona; Conway, James Ronald William; Sikta, Neblina; Oakes, Samantha Richelle; Cox, Thomas Robert; O'Donoghue, Sean Ignatius; Timpson, Paul; Ormandy, Christopher John; Gallego-Ortega, David

研究方向

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P
Paul Timpson
H 指数:70论文数:510被引数:1.4万
J
Johanna Ivaska
H 指数:71论文数:250被引数:1.8万
D
David Herrmann
H 指数:32论文数:319被引数:4,186
S
Sean Warren
H 指数:27论文数:75被引数:3,217
J
Jennifer P. Morton
H 指数:77论文数:391被引数:2.4万
A
Astrid Magenau
H 指数:31论文数:66被引数:3,818
O
Owen J. Sansom
H 指数:113论文数:1,190被引数:5.1万
C
Claire Vennin
H 指数:28论文数:152被引数:2,969
M
Max Nobis
H 指数:31论文数:139被引数:3,195
K
Kendelle J. Murphy
H 指数:19论文数:45被引数:2,161