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Optimization of Prodiginines as Single-Dose Curative Antimalarials 单剂量根治性抗疟药Prodiginines的优化 Kumar, Amrendra; Li, Yuexin; Zhang, Xiaowei; Gaddam, Mahesh; Caridha, Diana; Madejczyk, Michael S.; Jin, Xiannu; Dennis, William E.; Chetree, Ravi; Blount, Cameron; DeLuca, Jesse; Vuong, Chau; Kudyba, Karl; Roncal, Norma; Ashraf, Kutub; Lee, Patricia J.; Pannone, Kristina; Leed, Susan; Dinh, Hieu T.; Mdaki, Kennedy; Navarrete, Kimberly; Charlton, Jordan; Binauhan, Angely J.; Qahash, Tarrick; Kibe, Kevin Mugambi; Shoue, Douglas A.; Checkley, Lisa; Ferdig, Michael T.; Chim-Ong, Anongruk; Cui, Liwang; Orena, Stephen; Byaruhanga, Oswald; Assimwe, Jackson; Tibagambirwa, Innocent; Chithanna, Sivanna; Dodean, Rozalia A.; Legac, Jennifer; Kreutzfeld, Oriana; Rosenthal, Philip J.; Cooper, Roland A.; Reynolds, Kevin A.; Roth, Alison; Kelly, Jane X.; Kancharla, Papireddy 分享 收藏
The extended recovery ring-stage survival assay is a scalable alternative for artemisinin susceptibility phenotyping of fresh Plasmodium falciparum isolates 延长恢复环阶段存活试验是新鲜恶性疟原虫分离株青蒿素敏感性表型的可扩展替代方法 Okitwi, Martin; Shoue, Douglas A.; Checkley, Lisa A.; Orena, Stephen; Ceja, Frida G.; Taremwa, Yoweri; Tumwebaze, Patrick K.; Katairo, Thomas; Byaruhanga, Oswald; Sievert, Mackenzie A. C.; Garg, Shreeya; Kreutzfeld, Oriana K.; Legac, Jennifer; Bailey, Jeffrey A.; Nsobya, Sam L.; Conrad, Melissa D.; Rosenthal, Philip J.; Ferdig, Michael T.; Cooper, Roland A. 分享 收藏
MalKinID: A classification model for identifying malaria parasite genealogical relationships using identity-by-descent Wong, Wesley; Wang, Lea; Schaffner, Stephen F.; Li, Xue; Cheeseman, Ian; Anderson, Timothy J. C.; Vaughan, Ashley; Ferdig, Michael; Volkman, Sarah K.; Hartl, Daniel L.; Wirth, Dyann F. 分享 收藏
A Plasmodium falciparum genetic cross reveals the contributions of pfcrt and plasmepsin II/III to piperaquine drug resistance Kane, John; Li, Xue; Kumar, Sudhir; Button-Simons, Katrina A.; Brenneman, Katelyn M. Vendrely; Dahlhoff, Haley; Sievert, Mackenzie A. C.; Checkley, Lisa A.; Shoue, Douglas A.; Singh, Puspendra P.; Abatiyow, Biley A.; Haile, Meseret T.; Nair, Shalini; Reyes, Ann; Tripura, Rupam; Peto, Thomas J.; Lek, Dysoley; Mukherjee, Angana; Kappe, Stefan H. I.; Dhorda, Mehul; Nkhoma, Standwell C.; Cheeseman, Ian H.; Vaughan, Ashley M.; Anderson, Timothy J. C.; Ferdig, Michael T. 分享 收藏
Chemogenomic Profiling of a Plasmodium falciparum Transposon Mutant Library Reveals Shared Effects of Dihydroartemisinin and Bortezomib on Lipid Metabolism and Exported Proteins Pires, Camilla Valente; Oberstaller, Jenna; Wang, Chengqi; Casandra, Debora; Zhang, Min; Chawla, Jyotsna; Adapa, Swamy Rakesh; Otto, Thomas D.; Ferdig, Michael T.; Rayner, Julian C.; Jiang, Rays H. Y.; Adams, John H. 分享 收藏
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The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite Zhang, Min; Wang, Chengqi; Oberstaller, Jenna; Thomas, Phaedra; Otto, Thomas D.; Casandra, Debora; Boyapalle, Sandhya; Adapa, Swamy R.; Xu, Shulin; Button-Simons, Katrina; Mayho, Matthew; Rayner, Julian C.; Ferdig, Michael T.; Jiang, Rays H. Y.; Adams, John H. 分享 收藏
The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice Button-Simons, Katrina A.; Kumar, Sudhir; Carmago, Nelly; Haile, Meseret T.; Jett, Catherine; Checkley, Lisa A.; Kennedy, Spencer Y.; Pinapati, Richard S.; Shoue, Douglas A.; McDew-White, Marina; Li, Xue; Nosten, Francois H.; Kappe, Stefan H.; Anderson, Timothy J. C.; Romero-Severson, Jeanne; Ferdig, Michael T.; Emrich, Scott J.; Vaughan, Ashley M.; Cheeseman, Ian H. 分享 收藏
Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle Li, Xue; Kumar, Sudhir; McDew-White, Marina; Haile, Meseret; Cheeseman, Ian H.; Emrich, Scott; Button-Simons, Katie; Nosten, Francois; Kappe, Stefan H., I; Ferdig, Michael T.; Anderson, Tim J. C.; Vaughan, Ashley M. 分享 收藏
Leveraging crowdsourcing to accelerate global health solutions Davis, Sage; Button-Simons, Katrina; Bensellak, Taoufik; Ahsen, Eren Mehmet; Checkley, Lisa; Foster, Gabriel J.; Su, Xinzhuan; Moussa, Ahmed; Mapiye, Darlington; Khoo, Sok Kean; Nosten, Francois; Anderson, Timothy J. C.; Vendrely, Katelyn; Bletz, Julie; Yu, Thomas; Panji, Sumir; Ghouila, Amel; Mulder, Nicola; Norman, Thea; Kern, Steven; Meyer, Pablo; Stolovitzky, Gustavo; Ferdig, Michael T.; Siwo, Geoffrey H. 分享 收藏
Altered expression of K13 disrupts DNA replication and repair in Plasmodium falciparum Gibbons, Justin; Button-Simons, Katrina A.; Adapa, Swamy R.; Li, Suzanne; Pietsch, Maxwell; Zhang, Min; Liao, Xiangyun; Adams, John H.; Ferdig, Michael T.; Jiang, Rays H. Y. 分享 收藏
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Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum Miles, Alistair; Iqbal, Zamin; Vauterin, Paul; Pearson, Richard; Campino, Susana; Theron, Michel; Gould, Kelda; Mead, Daniel; Drury, Eleanor; O'Brien, John; Rubio, Valentin Ruano; MacInnis, Bronwyn; Mwangi, Jonathan; Samarakoon, Upeka; Ranford-Cartwright, Lisa; Ferdig, Michael; Hayton, Karen; Su, Xin-zhuan; Wellems, Thomas; Rayner, Julian; McVean, Gil; Kwiatkowski, Dominic 分享 收藏
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Van Voorhis, Wesley C.; Adams, John H.; Adelfio, Roberto; Ahyong, Vida; Akabas, Myles H.; Alano, Pietro; Alday, Aintzane; Resto, Yesmalie Aleman; Alsibaee, Aishah; Alzualde, Ainhoa; Andrews, Katherine T.; Avery, Simon V.; Avery, Vicky M.; Ayong, Lawrence; Baker, Mark; Baker, Stephen; Ben Mamoun, Choukri; Bhatia, Sangeeta; Bickle, Quentin; Bounaadja, Lotfi; Bowling, Tana; Bosch, Juergen; Boucher, Lauren E.; Boyom, Fabrice F.; Brea, Jose; Brennan, Marian; Burton, Audrey; Caffrey, Conor R.; Camarda, Grazia; Carrasquilla, Manuela; Carter, Dee; Cassera, Maria Belen; Cheng, Ken Chih-Chien; Chindaudomsate, Worathad; Chubb, Anthony; Colon, Beatrice L.; Colon-Lopez, Daisy D.; Corbett, Yolanda; Crowther, Gregory J.; Cowan, Noemi; D'Alessandro, Sarah; Le Dang, Na; Delves, Michael; DeRisi, Joseph L.; Du, Alan Y.; Duffy, Sandra; El-Sayed, Shimaa Abd El-Salam; Ferdig, Michael T.; Robledo, Jose A. Fernandez; Fidock, David A.; Florent, Isabelle; Fokou, Patrick V. T.; Galstian, Ani; Javier Gamo, Francisco; Gokool, Suzanne; Gold, Ben; Golub, Todd; Goldgof, Gregory M.; Guha, Rajarshi; Guiguemde, W. Armand; Gural, Nil; Guy, R. Kiplin; Hansen, Michael A. E.; Hanson, Kirsten K.; Hemphill, Andrew; van Huijsduijnen, Rob Hooft; Horii, Takaaki; Horrocks, Paul; Hughes, Tyler B.; Huston, Christopher; Igarashi, Ikuo; Ingram-Sieber, Katrin; Itoe, Maurice A.; Jadhav, Ajit; Jensen, Amornrat Naranuntarat; Jensen, Laran T.; Jiang, Rays H. Y.; Kaiser, Annette; Keiser, Jennifer; Ketas, Thomas; Kicka, Sebastien; Kim, Sunyoung; Kirk, Kiaran; Kumar, Vidya P.; Kyle, Dennis E.; Jose Lafuente, Maria; Landfear, Scott; Lee, Nathan; Lee, Sukjun; Lehane, Adele M.; Li, Fengwu; Little, David; Liu, Liqiong; Llinas, Manuel; Loza, Maria I.; Lubar, Aristea; Lucantoni, Leonardo; Lucet, Isabelle; Maes, Louis; Mancama, Dalu; Mansour, Nuha R.; March, Sandra; McGowan, Sheena; Vera, Iset Medina; Meister, Stephan; Mercer, Luke; Mestres, Jordi; Mfopa, Alvine N.; Misra, Raj N.; Moon, Seunghyun; Moore, John P.; Rodrigues da Costa, Francielly Morais; Mueller, Joachim; Muriana, Arantza; Hewitt, Stephen Nakazawa; Nare, Bakela; Nathan, Carl; Narraidoo, Nathalie; Nawaratna, Sujeevi; Ojo, Kayode K.; Ortiz, Diana; Panic, Gordana; Papadatos, George; Parapini, Silvia; Patra, Kailash; Ngoc Pham; Prats, Sarah; Plouffe, David M.; Poulsen, Sally-Ann; Pradhan, Anupam; Quevedo, Celia; Quinn, Ronald J.; Rice, Christopher A.; Rizk, Mohamed Abdo; Ruecker, Andrea; St Onge, Robert; Ferreira, Rafaela Salgado; Samra, Jasmeet; Robinett, Natalie G.; Schlecht, Ulrich; Schmitt, Marjorie; Villela, Filipe Silva; Silvestrini, Francesco; Sinden, Robert; Smith, Dennis A.; Soldati, Thierry; Spitzmueller, Andreas; Stamm, Serge Maximilian; Sullivan, David J.; Sullivan, William; Suresh, Sundari; Suzuki, Brian M.; Suzuki, Yo; Swamidass, S. Joshua; Taramelli, Donatella; Tchokouaha, Lauve R. Y.; Theron, Anjo; Thomas, David; Tonissen, Kathryn F.; Townson, Simon; Tripathi, Abhai K.; Trofimov, Valentin; Udenze, Kenneth O.; Ullah, Imran; Vallieres, Cindy; Vigil, Edgar; Vinetz, Joseph M.; Phat Voong Vinh; Hoan Vu; Watanabe, Nao-aki; Weatherby, Kate; White, Pamela M.; Wilks, Andrew F.; Winzeler, Elizabeth A.; Wojcik, Edward; Wree, Melanie; Wu, Wesley; Yokoyama, Naoaki; Zollo, Paul H. A.; Abla, Nada; Blasco, Benjamin; Burrows, Jeremy; Laleu, Benoit; Leroy, Didier; Spangenberg, Thomas; Wells, Timothy; Willis, Paul A. 分享 收藏
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Population Structure Shapes Copy Number Variation in Malaria Parasites Cheeseman, Ian H.; Miller, Becky; Tan, John C.; Tan, Asako; Nair, Shalini; Nkhoma, Standwell C.; De Donato, Marcos; Rodulfo, Hectorina; Dondorp, Arjen; Branch, Oralee H.; Ruiz Mesia, Lastenia; Newton, Paul; Mayxay, Mayfong; Amambua-Ngwa, Alfred; Conway, David J.; Nosten, Francois; Ferdig, Michael T.; Anderson, Tim J. C. 分享 收藏
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