Alex S. Kiselyov - Publications, H-index & Citations

Alex S. Kiselyov

moscow institute of physics & technology

25H指数

80论文数

2.1K被引数

收录论文 24

发表时间

Design and development of microformulations for rapid release of small molecules and oligonucleotides

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2023-09-01

OAAI

Brown, T.; Stanton, M.; Cros, F.; Cho, S.; Kiselyov, A.

Robust Reductions of Body Weight and Food Intake by an Oxytocin Analog in Rats

FRONTIERS IN PHYSIOLOGY

IF3.4

2021-09-27

OAAI

Elfers, Clinton T.; Blevins, James E.; Lawson, Elizabeth A.; Pittner, Richard; Silva, David; Kiselyov, Alex; Roth, Christian L.

Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates

SCIENTIFIC REPORTS

IF3.9

2021-09-09

OAAI

Herrmann, Frank; Hessmann, Manuela; Schaertl, Sabine; Berg-Rosseburg, Karola; Brown, Christopher J.; Bursow, Galina; Chiki, Anass; Ebneth, Andreas; Gehrmann, Miriam; Hoeschen, Nicole; Hotze, Madlen; Jahn, Stefanie; Johnson, Peter D.; Khetarpal, Vinod; Kiselyov, Alex; Kottig, Karsten; Ladewig, Stefanie; Lashuel, Hilal; Letschert, Sven; Mills, Matthew R.; Petersen, Kathrin; Prime, Michael E.; Scheich, Christoph; Schmiedel, Gerhard; Wityak, John; Liu, Longbin; Dominguez, Celia; Munoz-Sanjuan, Ignacio; Bard, Jonathan A.

Synthesis and anti-mitotic activity of 6,7-dihydro-4H-isothiazolo [4,5-b]pyridin-5-ones: In vivo and cell-based studies

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2017-01-01

PREAI

Semenov, Victor V.; Lichitsky, Boris V.; Komogortsev, Andrey N.; Dudinov, Arkady A.; Krayushkin, Mikhail M.; Konyushkin, Leonid D.; Atamanenko, Olga P.; Karmanova, Irina B.; Strelenko, Yuri A.; Shor, Boris; Semenova, Marina N.; Kiselyov, Alex S.

3-Amino-thieno[2,3-b]pyridines as microtubule-destabilising agents: Molecular modelling and biological evaluation in the sea urchin embryo and human cancer cells

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2017-01-01

PREAI

Eurtivong, Chatchakorn; Semenov, Victor; Semenova, Marina; Konyushkin, Leonid; Atamanenko, Olga; Reynisson, Johannes; Kiselyov, Alex

Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity

JOURNAL OF NATURAL PRODUCTS

IF3.6

2016-04-21

PREAI

Semenov, Victor V.; Tsyganov, Dmitry V.; Semenova, Marina N.; Chuprov-Netochin, Roman N.; Raihstat, Mikhail M.; Konyushkin, Leonid D.; Volynchuk, Polina B.; Marusich, Elena I.; Nazarenko, Vera V.; Leonov, Sergey V.; Kiselyov, Alex S.

Key signaling pathways in the muscle-invasive bladder carcinoma: Clinical markers for disease modeling and optimized treatment

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2015-11-23

OAAI

Kiselyov, Alex; Bunimovich-Mendrazitsky, Svetlana; Startsev, Vladimir

A facile synthesis and microtubule-destabilizing properties of 4-(1H-benzo[d]imidazol-2-yl)-furazan-3-amines

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2015-04-01

PREAI

Stepanov, Andrei I.; Astrat'ev, Alexander A.; Sheremetev, Aleksei B.; Lagutina, Nataliya K.; Palysaeva, Nadezhda V.; Tyurin, Aleksei Yu.; Aleksandrova, Nataliya S.; Sadchikova, Nataliya P.; Suponitsky, Kyrill Yu.; Atamanenko, Olga P.; Konyushkin, Leonid D.; Semenov, Roman V.; Firgang, Sergei I.; Kiselyov, Alex S.; Semenova, Marina N.; Semenov, Victor V.

Lead Optimization toward Proof-of-Concept Tools for Huntington's Disease within a 4-(1H-Pyrazol-4-yl)pyrimidine Class of Pan-JNK Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2015-03-19

PREAI

Wityak, John; McGee, Kevin F.; Conlon, Michael P.; Song, Ren Hua; Duffy, Bryan C.; Clayton, Brent; Lynch, Michael; Wang, Gwen; Freeman, Emily; Haber, James; Kitchen, Douglas B.; Manning, David D.; Ismail, Jiffry; Khmelnitsky, Yuri; Michels, Peter; Webster, Jeff; Irigoyen, Macarena; Luche, Michele; Hultman, Monica; Bai, Mei; Kuok, IokTeng D.; Newell, Ryan; Lamers, Marieke; Leonard, Philip; Yates, Dawn; Matthews, Kim; Ongeri, Lynette; Clifton, Steve; Mead, Tania; Deupree, Susan; Wheelan, Pat; Lyons, Kathy; Wilson, Claire; Kiselyov, Alex; Toledo-Sherman, Leticia; Beconi, Maria; Munoz-Sanjuan, Ignacio; Bard, Jonathan; Dominguez, Celia

3-(5-)-Amino-o-diarylisoxazoles: Regioselective synthesis and antitubulin activity

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2014-02-01

PREAI

Tsyganov, Dmitry V.; Khrustalev, Victor N.; Konyushkin, Leonid D.; Raihstat, Mikhail M.; Firgang, Sergei I.; Semenov, Roman V.; Kiselyov, Alex S.; Semenova, Marina N.; Semenov, Victor V.

Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2014-01-01

PREAI

Demchuk, Dmitry V.; Samet, Alexander V.; Chernysheva, Natalia B.; Ushkarov, Vladimir I.; Stashina, Galina A.; Konyushkin, Leonid D.; Raihstat, Mikhail M.; Firgang, Sergei I.; Philchenkov, Alex A.; Zavelevich, Michael P.; Kuiava, Ludmila M.; Chekhun, Vasyl F.; Blokhin, Dmitry Yu.; Kiselyov, Alex S.; Semenova, Marina N.; Semenov, Victor V.

cis-Restricted 3-Aminopyrazole Analogues of Combretastatins: Synthesis from Plant Polyalkoxybenzenes and Biological Evaluation in the Cytotoxicity and Phenotypic Sea Urchin Embryo Assays

JOURNAL OF NATURAL PRODUCTS

IF3.6

2013-08-07

PREAI

Tsyganov, Dmitry V.; Konyushkin, Leonid D.; Karmanova, Irina B.; Firgang, Sergei I.; Strelenko, Yuri A.; Semenova, Marina N.; Kiselyov, Alex S.; Semenov, Victor V.

Polyalkoxybenzenes from Plants. 5. Parsley Seed Extract in Synthesis of Azapodophyllotoxins Featuring Strong Tubulin Destabilizing Activity in the Sea Urchin Embryo and Cell Culture Assays

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2011-09-29

PREAI

Semenova, Marina N.; Kiselyov, Alex S.; Tsyganov, Dmitry V.; Konyushkin, Leonid D.; Firgang, Sergei I.; Semenov, Roman V.; Malyshey, Oleg R.; Raihstat, Mikhail M.; Fuchs, Fabian; Stielow, Anne; Lantow, Margareta; Philchenkov, Alex A.; Zavelevich, Michael P.; Zefirov, NIkolay S.; Kuznetsov, Sergei A.; Semenov, Victor V.

Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays 1,3，4-恶二唑的新型衍生物是有效的线粒体抑制剂，在海胆胚胎和细胞培养测定中具有很强的微管解聚活性

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2010-05-01

PREAI

Kiselyov, Alex S.; Semenova, Marina N.; Chernyshova, Natalya B.; Leitao, Andrei; Samet, Alexandr V.; Kislyi, Konstantine A.; Raihstat, Mikhail M.; Oprea, Tudor; Lemcke, Heiko; Lantow, Margareta; Weiss, Dieter G.; Ikizalp, Nazli N.; Kuznetsov, Sergei A.; Semenov, Victor V.

Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety 设计磷酸二酯酶4D (PDE4D) 变构调节剂以增强认知并提高安全性

NATURE BIOTECHNOLOGY

IF41.7

2010-01-01

367

PREAI

Burgin, Alex B.; Magnusson, Olafur T.; Singh, Jasbir; Witte, Pam; Staker, Bart L.; Bjornsson, Jon M.; Thorsteinsdottir, Margret; Hrafnsdottir, Sigrun; Hagen, Timothy; Kiselyov, Alex S.; Stewart, Lance J.; Gurney, Mark E.

Structure-Activity Relationship Studies Leading to the Identification of (2E)-3-[1-[2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-1H-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041), a Potent and Selective Prostanoid EP3 Receptor Antagonist, as a Novel Antiplatelet Agent That Does Not Prolong Bleeding

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-12-03

PREAI

Singh, Jasbir; Zeller, Wayne; Zhou, Nian; Hategan, Georgeta; Mishra, Rama K.; Polozov, Alex; Yu, Peng; Onua, Emmanuel; Zhang, Jun; Ramirez, Jose L.; Sigthorsson, Gudmundur; Thorsteinnsdottir, Margret; Kiselyov, Alex. S.; Zembower, David E.; Andresson, Thorkell; Gurney, Mark E.

Discovery of 4-[(2S)-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic Acid (DG-051) as a Novel Leukotriene A4 Hydrolase Inhibitor of Leukotriene B4 Biosynthesis

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-12-01

PREAI

Sandanayaka, Vincent; Mamat, Bjorn; Mishra, Rama K.; Winger, Jennifer; Krohn, Michael; Zhou, Li-Ming; Keyvan, Monica; Enache, Livia; Sullins, David; Onua, Emmanuel; Zhang, Jun; Halldorsdottir, Gudrun; Sigthorsdottir, Heida; Thorlaksdottir, Audur; Sigthorsson, Gudmundur; Thorsteinnsdottir, Margret; Davies, Douglas R.; Stewart, Lance J.; Zembower, David E.; Andresson, Thorkell; Kiselyov, Alex S.; Singh, Jasbir; Gurney, Mark E.

Development of a Scalable Synthetic Process for DG-051B, A First-in-Class Inhibitior of LTA4H

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2009-11-02

PREAI

Enache, Livia A.; Kennedy, Isaac; Sullins, David W.; Chen, Wei; Ristic, Dragan; Stahl, Glenn L.; Dzekhtser, Sergey; Erickson, Robert A.; Yan, Changren; Muellner, Frank W.; Krohn, Michael D.; Winger, Jennifer; Sandanayaka, Vincent; Singh, Jasbir; Zembower, David E.; Kiselyov, Alex S.

Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-07-20

115

OAAI

Davies, Douglas R.; Mamat, Bjorn; Magnusson, Olafur T.; Christensen, Jeff; Haraldsson, Magnus H.; Mishra, Rama; Pease, Brian; Hansen, Erik; Singh, Jasbir; Zembower, David; Kim, Hidong; Kisclyov, Alex S.; Burgin, Alex B.; Gurney, Mark E.; Stewart, Lance J.

Antagonists of the EP3 Receptor for Prostaglandin E2 Are Novel Antiplatelet Agents That Do Not Prolong Bleeding

ACS CHEMICAL BIOLOGY

IF3.8

2009-02-05

PREAI

Singh, Jasbir; Zeller, Wayne; Zhou, Nian; Hategen, Georgeta; Mishra, Rama; Polozov, Alex; Yu, Peng; Onua, Emmanuel; Zhang, Jun; Zembower, David; Kiselyov, Alex; Ramirez, Jose L.; Sigthorsson, Gudmundur; Bjornsson, Jon Mar; Thorsteinsdottir, Margret; Andresson, Thorkell; Bjarnadottir, Maria; Magnusson, Olafur; Fabre, Jean-Etienne; Stefansson, Kari; Gurney, Mark E.

研究方向