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H

Hyeung‐geun Park

Seoul National University

33H指数
186论文数
3.6K被引数
收录论文 66
发表时间
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Synthesis and Structure–Activity Relationship Study of 2-(amino)quinazolin-4(3H)-one Derivatives as Potential Inhibitors of Methicillin-Resistant Staphylococcus aureus (MRSA)2-(氨基)喹唑啉-4(3H)-酮衍生物的合成及其构效关系研究，作为耐甲氧西林金黄色葡萄球菌(MRSA)的潜在抑制剂
errAntibiotics 2025, Vol. 14, Page 967
IF0
err2025-09-26
err0
errOAAI
errJun Young Lee; Hyunjung Lee; Sungmin Kim; Jihwan Gim; Yunmi Lee; Chae Jo Lim; Hyun-Seob Song; Hyeung-geun Park; Soojin Jang; Chul Min Park
err分享
err收藏
Discovery of 3-acyl-2-anilino-1,4-dihydroquinolin-4-one derivatives as potential inhibitors of methicillin-resistant Staphylococcus aureus3-乙酰基-2-苯胺基-1,4-二氢喹啉-4-酮衍生物作为耐甲氧西林金黄色葡萄球菌潜在抑制剂的发现
errBIOORGANIC & MEDICINAL CHEMISTRY LETTERS
IF2.2
err2025-04-01
err0
PREAI
errLee, Jun Young; Kim, Sungmin; Gim, Jihwan; Lee, Yunmi; Lee, Hyunjung; Lim, Chae Jo; Song, Hyun-Seob; Park, Hyeung-geun; Jang, Soojin; Park, Chul Min
err分享
err收藏
Antitumor activity of selenopsammaplin A analog (SPA-10091-HCl) via histone methyltransferase DOT1L degradation and apoptosis induction in castration-resistant prostate cancer cells
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2025-02-01
err0
errOAAI
errHan, Jaeho; Yang, Sehun; Byun, Woong Sub; Jang, Sung Chul; Bae, Eun Seo; Park, Hyeung-geun; Lee, Sang Kook
err分享
err收藏
Discovery of Spirosnuolides A-D, Type I/III Hybrid Polyketide Spiro-Macrolides for a Chemotherapeutic Lead against Lung Cancer发现Spirosnuolides a-d，I/III型杂合聚酮化合物螺环大环内酯类用于抗肺癌的化疗先导物
errJACS AU
IF8.7
err2024-12-10
err0
errOAAI
errHuynh, Thanh-Hau; Jang, Sung Chul; Ban, Yeon Hee; Lee, Eun-Young; Kim, Taeho; Kang, Ilnam; An, Joon Soo; Kang, Sangwook; Han, Jaeho; Kwon, Yun; Oh, Daehyun; Park, Hyeung-geun; Cho, Jang-Cheon; Jang, Jichan; Oh, Ki-Bong; Nam, Sang-Jip; Lee, Sang Kook; Oh, Dong-Chan
err分享
err收藏
Tunicamycins from Marine-Derived Streptomyces bacillaris Inhibit MurNAc-Pentapeptide Translocase in Staphylococcus aureus
errMARINE DRUGS
IF5.4
err2024-06-26
err1
errOAAI
errLee, Jayho; Hwang, Ji-Yeon; Oh, Daehyun; Oh, Dong-Chan; Park, Hyeung-geun; Shin, Jongheon; Oh, Ki-Bong
err分享
err收藏
Enantioselective Synthesis of (R)-Sitagliptin via Phase-Transfer Catalytic aza-Michael Addition
errACS OMEGA
IF4.3
err2024-03-21
err2
errOAAI
errOh, Daehyun; Lee, Jaeyong; Yang, Sehun; Jung, So Hyun; Kim, Mihyun; Lee, Geumwoo; Park, Hyeung-geun
err分享
err收藏
An RORα agonist, ODH-08, inhibits fibrogenic activation of hepatic stellate cells via suppression of SMAD3RORα 激动剂ODH-08通过抑制SMAD3抑制肝星状细胞的纤维化激活
errLIFE SCIENCES
IF5.1
err2024-03-01
err3
PREAI
errChoi, Haena; Oh, Daehyun; Kim, Hyeon-Ji; Chambugong, Melody; Kim, Mi-Hyun; Lee, Mi-Ock; Park, Hyeung-Geun
err分享
err收藏
Novel SARS-CoV-2 entry inhibitors, 2-anilinoquinazolin-4(3H)-one derivatives, show potency as SARS-CoV-2 antivirals in a human ACE2 transgenic mouse model
errJOURNAL OF MEDICAL VIROLOGY
IF4.6
err2023-06-13
err1
PREAI
errKo, Meehyun; Lee, Jun Young; Shin, Young Sup; Jeon, Sangeun; Myung, Subeen; Cho, Jung-Eun; Jang, Min Seong; Song, Jong Hwan; Kim, Hyoung Rae; Park, Hyeung-geun; Park, Chul Min; Kim, Seungtaek
err分享
err收藏
Synthesis of chiral malonates by a-alkylation of 2,2-diphenylethyl tert-butyl malonates via enantioselective phase-transfer catalysis
errFRONTIERS IN CHEMISTRY
IF4.2
err2023-06-08
err1
errOAAI
errGuo, Zhibin; Oh, Daehyun; Sagong, Min; Yang, Jewon; Lee, Geumwoo; Park, Hyeung-geun
err分享
err收藏
Optimization of 2-Aminoquinazolin-4-(3H)-one Derivatives as Potent Inhibitors of SARS-CoV-2: Improved Synthesis and Pharmacokinetic Properties
errPHARMACEUTICALS
IF4.8
err2022-07-04
err7
errOAAI
errShin, Young Sup; Lee, Jun Young; Jeon, Sangeun; Cho, Jung-Eun; Myung, Subeen; Jang, Min Seong; Kim, Seungtaek; Song, Jong Hwan; Kim, Hyoung Rae; Park, Hyeung-geun; Jeong, Lak Shin; Park, Chul Min
err分享
err收藏
Inhibition of Streptococcus mutans adhesion and biofilm formation with small-molecule inhibitors of sortase A from Juniperus chinensis
errJOURNAL OF ORAL MICROBIOLOGY
IF5.5
err2022-06-14
err6
errOAAI
errCho, Eunji; Hwang, Ji-Yeon; Park, Jae Sung; Oh, Daehyun; Oh, Dong-Chan; Park, Hyeung-Geun; Shin, Jongheon; Oh, Ki-Bong
err分享
err收藏
Asymmetric Phase-Transfer Catalytic aza-Michael Addition to Cyclic Enone: Highly Enantioselective and Diastereoselective Synthesis of Cyclic 1,3-Aminoalcohols
errORGANIC LETTERS
IF5
err2022-02-17
err6
PREAI
errLee, Jaeyong; Ban, Jeong Woo; Kim, Jeongseok; Yang, Sehun; Lee, Geumwoo; Dhorma, Lama Prema; Kim, Mi-hyun; Ha, Min Woo; Hong, Suckchang; Park, Hyeung-geun
err分享
err收藏
Psammocindoles A-C: Isolation, Synthesis, and Bioactivity of Indole-γ-lactams from the Sponge Psammocinia vermis
errORGANIC LETTERS
IF5
err2021-06-01
err7
PREAI
errKwon, Oh-Seok; Ahn, Sungjin; Jeon, Ju-eun; Park, In Guk; Won, Tae Hyung; Sim, Chung J.; Park, Hyeung-geun; Oh, Dong-Chan; Oh, Ki-Bong; Noh, Minsoo; Shin, Jongheon
err分享
err收藏
Synthesis and biological activity of selenopsammaplin A and its analogues as antitumor agents with DOT1L inhibitory activity具有DOT1L抑制活性的硒代马普林A及其类似物的合成和生物活性
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2021-04-01
err10
PREAI
errHan, Hae Ju; Byun, Woong Sub; Lee, Gyu Ho; Kim, Won Kyung; Jang, Kyungkuk; Yang, Sehun; Yang, Jewon; Ha, Min Woo; Hong, Suckchang; Lee, Jeeyeon; Shin, Jongheon; Oh, Ki Bong; Lee, Sang Kook; Park, Hyeung-geun
err分享
err收藏
Enantioselective Total Synthesis of Nitraria Alkaloids: (+)-Nitramine, (+)-Isonitramine, (-)-Isonitramine, and (-)-Sibirine via Asymmetric Phase-Transfer Catalytic α-Allylations of α-Carboxylactams
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2021-01-19
err11
PREAI
errYang, Jewon; Park, Yohan; Yang, Sehun; Lee, Geumwoo; Ha, Min Woo; Kim, Mi-hyun; Hong, Suckchang; Park, Hyeung-geun
err分享
err收藏
Inhibition of DOT1L by Half-Selenopsammaplin A Analogs Suppresses Tumor Growth and EMT-Mediated Metastasis in Triple-Negative Breast Cancer
errPHARMACEUTICALS
IF4.8
err2020-12-28
err7
errOAAI
errByun, Woong Sub; Lee, Gyu Ho; Park, Hyeung-geun; Lee, Sang Kook
err分享
err收藏
Enantioselective Synthesis of (+)-Coerulescine by a Phase-Transfer Catalytic Allylation of Diphenylmethyl tert-Butyl α-(2-Nitrophenyl)Malonate
errFRONTIERS IN CHEMISTRY
IF4.2
err2020-11-12
err4
errOAAI
errLee, Sangki; Yang, Jewon; Yang, Sehun; Lee, Geumwoo; Oh, Daehyun; Ha, Min Woo; Hong, Suckchang; Park, Hyeung-geun
err分享
err收藏
Targeting Histone Methyltransferase DOT1L by a Novel Psammaplin A Analog Inhibits Growth and Metastasis of Triple-Negative Breast Cancer
errMOLECULAR THERAPY-ONCOLYTICS
IF0
err2019-12-01
err32
errOAAI
errByun, Woong Sub; Kim, Won Kyung; Han, Hae Ju; Chung, Hwa-Jin; Jang, Kyungkuk; Kim, Han Sun; Kim, Sunghwa; Kim, Donghwa; Bae, Eun Seo; Park, Sunghyouk; Lee, Jeeyeon; Park, Hyeung-geun; Lee, Sang Kook
err分享
err收藏
Chemistry-oriented synthesis (ChOS) and target deconvolution on neuroprotective effect of a novel scaffold, oxaza spiroquinone
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2019-02-01
err15
PREAI
errVenkanna, Arramshetti; Cho, Kyo Hee; Dhorma, Lama Prema; Kumar, Duddukuri Nandan; Hah, Jung Mi; Park, Hyeung-geun; Kim, Sun Yeou; Kim, Mi-hyun
err分享
err收藏
Enantioselective Synthesis of Chiral α-Thio-Quaternary Stereogenic Centers via Phase-Transfer-Catalyzed α-Alkylation of α-Acylthiomalonates
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2018-01-10
err4
PREAI
errHa, Min Woo; Lee, Jun Young; Kim, Doyoung; Lee, Geumwoo; Lee, Jae Kyun; Hong, Suckchang; Park, Hyeung-geun
err分享
err收藏

研究方向

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