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T

Taekyu Lee

Vanderbilt University School of Medicine
H指数:18
被引数:2,334

个人简介

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教育背景

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工作经历

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荣誉奖项

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Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent In Vivo Activities in Mouse Models of Hematological and Solid Tumors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-08-052
OAAI
Tarr, James C.; Salovich, James M.; Aichinger, Martin; Jeon, Kyuok; Veerasamy, Nagarathanam; Sensintaffar, John L.; Arnhof, Heribert; Samwer, Matthias; Christov, Plamen P.; Kim, Kwangho; Wunberg, Tobias; Schweifer, Norbert; Trapani, Francesca; Arnold, Allison; Martin, Florian; Zhao, Bin; Miriyala, Nagaraju; Sgubin, Danielle; Fogarty, Stuart; Moore, William J.; Stott, Gordon M.; Olejniczak, Edward T.; Engelhardt, Harald; Rudolph, Dorothea; Lee, Taekyu; Mcconnell, Darryl B.; Fesik, Stephen W.
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-12-2712
OAAI
Teuscher, Kevin B.; Chowdhury, Somenath; Meyers, Kenneth M.; Tian, Jianhua; Sai, Jiqing; Van Meveren, Mayme; South, Taylor M.; Sensintaffar, John L.; Rietz, Tyson A.; Goswami, Soumita; Wang, Jing; Grieb, Brian C.; Lorey, Shelly L.; Howard, Gregory C.; Liu, Qi; Moore, William J.; Stott, Gordon M.; Tansey, William P.; Leea, Taekyu; Fesik, Stephen W.
Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-12-2047
OAAI
Tian, Jianhua; Teuscher, Kevin B.; Aho, Erin R.; Alvarado, Joseph R.; Mills, Jonathan J.; Meyers, Kenneth M.; Gogliotti, Rocco D.; Han, Changho; Macdonald, Jonathan D.; Sai, Jiqing; Shaw, J. Grace; Sensintaffar, John L.; Zhao, Bin; Rietz, Tyson A.; Thomas, Lance R.; Payne, William G.; Moore, William J.; Stott, Gordon M.; Kondo, Jumpei; Inoue, Masahiro; Coffey, Robert J.; Tansey, William P.; Stauffer, Shaun R.; Lee, Taekyu; Fesik, Stephen W.
Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-03-3051
OAAI
Lee, Taekyu; Christov, Plamen P.; Shaw, Subrata; Tarr, James C.; Zhao, Bin; Veerasamy, Nagarathanam; Jeon, Kyu Ok; Mills, Jonathan J.; Bian, Zhiguo; Sensintaffar, John L.; Arnold, Allison L.; Fogarty, Stuart A.; Perry, Evan; Ramsey, Haley E.; Cook, Rebecca S.; Hollingshead, Melinda; Millin, Myrtle Davis; Lee, Kyung-min; Koss, Brian; Budhraja, Amit; Opferman, Joseph T.; Kim, Kwangho; Arteaga, Carlos L.; Moore, William J.; Olejniczak, Edward T.; Savona, Michael R.; Fesik, Stephen W.
A Novel MCL1 Inhibitor Combined with Venetoclax Rescues Venetoclax-Resistant Acute Myelogenous Leukemia

一种新型MCL1抑制剂联合维尼托克治疗维尼托克耐药急性髓系白血病

CANCER DISCOVERY
IF33.3
2018-12-03279
OAAI
Ramsey, Haley E.; Fischer, Melissa A.; Lee, Taekyu; Gorskal, Agnieszka E.; Arratel, Maria Pia; Fuller, Londa; Boyd, Kelli L.; Strickland, Stephen A.; Sensintaffar, John; Hogdal, Leah J.; Ayerss, Gregory D.; Olejniczak, Edward T.; Fesik, Stephen W.; Savona, Michael R.
Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors
FEBS LETTERS
IF3
2016-12-1961
OAAI
Lee, Taekyu; Bian, Zhiguo; Zhao, Bin; Hogdal, Leah J.; Sensintaffar, John L.; Goodwin, Craig M.; Belmar, Johannes; Shaw, Subrata; Tarr, James C.; Veerasamy, Nagarathanam; Matulis, Shannon M.; Koss, Brian; Fischer, Melissa A.; Arnold, Allison L.; Camper, DeMarco V.; Browning, Carrie F.; Rossanese, Olivia W.; Budhraja, Amit; Opferman, Joseph; Boise, Lawrence H.; Savona, Michael R.; Letai, Anthony; Olejniczak, Edward T.; Fesik, Stephen W.

研究方向

暂未获取到该数据
S
Stephen W. Fesik
H 指数:97论文数:432被引数:4.4万
E
Edward T. Olejniczak
H 指数:63论文数:246被引数:1.3万
J
John Sensintaffar
H 指数:23论文数:129被引数:4,907
B
Bin Zhao
H 指数:33论文数:106被引数:3,107
A
Allison L. Arnold
H 指数:9论文数:31被引数:471
O
Olivia W. Rossanese
H 指数:30论文数:92被引数:3,580
S
Subrata Shaw
H 指数:19论文数:49被引数:2,437
D
DeMarco V. Camper
H 指数:14论文数:39被引数:1,204
J
James C. Tarr
H 指数:16论文数:48被引数:1,055
C
Craig M. Goodwin
H 指数:15论文数:153被引数:1,639