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B

Bin Zhao

chinese academy of medical sciences - peking union medical college
H指数:33
被引数:3,100

个人简介

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教育背景

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工作经历

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荣誉奖项

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Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent In Vivo Activities in Mouse Models of Hematological and Solid Tumors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-08-052
OAAI
Tarr, James C.; Salovich, James M.; Aichinger, Martin; Jeon, Kyuok; Veerasamy, Nagarathanam; Sensintaffar, John L.; Arnhof, Heribert; Samwer, Matthias; Christov, Plamen P.; Kim, Kwangho; Wunberg, Tobias; Schweifer, Norbert; Trapani, Francesca; Arnold, Allison; Martin, Florian; Zhao, Bin; Miriyala, Nagaraju; Sgubin, Danielle; Fogarty, Stuart; Moore, William J.; Stott, Gordon M.; Olejniczak, Edward T.; Engelhardt, Harald; Rudolph, Dorothea; Lee, Taekyu; Mcconnell, Darryl B.; Fesik, Stephen W.
Impact of WIN site inhibitor on the WDR5 interactome
CELL REPORTS
IF6.9
2021-01-0136
OAAI
Guarnaccia, Alissa D.; Rose, Kristie L.; Wang, Jing; Zhao, Bin; Popay, Tessa M.; Wang, Christina E.; Guerrazzi, Kiana; Hill, Salisha; Woodley, Chase M.; Hansen, Tyler J.; Lorey, Shelly L.; Shaw, J. Grace; Payne, William G.; Weissmiller, April M.; Olejniczak, Edward T.; Fesik, Stephen W.; Liu, Qi; Tansey, William P.
Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-12-2047
OAAI
Tian, Jianhua; Teuscher, Kevin B.; Aho, Erin R.; Alvarado, Joseph R.; Mills, Jonathan J.; Meyers, Kenneth M.; Gogliotti, Rocco D.; Han, Changho; Macdonald, Jonathan D.; Sai, Jiqing; Shaw, J. Grace; Sensintaffar, John L.; Zhao, Bin; Rietz, Tyson A.; Thomas, Lance R.; Payne, William G.; Moore, William J.; Stott, Gordon M.; Kondo, Jumpei; Inoue, Masahiro; Coffey, Robert J.; Tansey, William P.; Stauffer, Shaun R.; Lee, Taekyu; Fesik, Stephen W.
Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-11-1448
OAAI
Macdonald, Jonathan D.; Simon, Selena Chacon; Han, Changho; Wang, Fen; Shaw, J. Grace; Howes, Jennifer E.; Sai, Jiqing; Yuh, Joannes P.; Camper, Demarco; Alicie, Bethany M.; Alvarado, Joseph; Nikhar, Sameer; Payne, William; Aho, Erin R.; Bauer, Joshua A.; Zhao, Bin; Phan, Jason; Thomas, Lance R.; Rossanese, Olivia W.; Tansey, William P.; Waterson, Alex G.; Stauffer, Shaun R.; Fesik, Stephen W.
Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-03-3051
OAAI
Lee, Taekyu; Christov, Plamen P.; Shaw, Subrata; Tarr, James C.; Zhao, Bin; Veerasamy, Nagarathanam; Jeon, Kyu Ok; Mills, Jonathan J.; Bian, Zhiguo; Sensintaffar, John L.; Arnold, Allison L.; Fogarty, Stuart A.; Perry, Evan; Ramsey, Haley E.; Cook, Rebecca S.; Hollingshead, Melinda; Millin, Myrtle Davis; Lee, Kyung-min; Koss, Brian; Budhraja, Amit; Opferman, Joseph T.; Kim, Kwangho; Arteaga, Carlos L.; Moore, William J.; Olejniczak, Edward T.; Savona, Michael R.; Fesik, Stephen W.
Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity
CELL REPORTS
IF6.9
2019-03-0188
OAAI
Aho, Erin R.; Wang, Jing; Gogliotti, Rocco D.; Howard, Gregory C.; Phan, Jason; Acharya, Pankaj; Macdonald, Jonathan D.; Cheng, Ken; Lorey, Shelly L.; Lu, Bin; Wenzel, Sabine; Foshage, Audra M.; Alvarado, Joseph; Wang, Feng; Shaw, J. Grace; Zhao, Bin; Weissmiller, April M.; Thomas, Lance R.; Vakoc, Christopher R.; Hall, Matthew D.; Hiebert, Scott W.; Liu, Qi; Stauffer, Shaun R.; Fesik, Stephen W.; Tansey, William P.

研究方向

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S
Stephen W. Fesik
H 指数:97论文数:432被引数:4.4万
T
Taekyu Lee
H 指数:18论文数:76被引数:2,333
E
Edward T. Olejniczak
H 指数:63论文数:246被引数:1.3万
M
Michael R. Waterman
H 指数:81论文数:460被引数:2.7万
J
John Sensintaffar
H 指数:23论文数:129被引数:4,905
D
David C. Lamb
H 指数:52论文数:169被引数:1.2万
S
Steven L. Kelly
H 指数:65论文数:294被引数:1.7万
A
Allison L. Arnold
H 指数:9论文数:31被引数:470
W
William P. Tansey
H 指数:45论文数:174被引数:8,561
O
Olivia W. Rossanese
H 指数:30论文数:92被引数:3,576