James M. Holton - Publications, H-index & Citations

James M. Holton

lawrence berkeley national laboratory

52H指数

179论文数

1.4W被引数

收录论文 44

发表时间

An additional water is introduced into the manganese cluster during the formation of the S3 state of photosystem II 在光合系统II的S3状态形成过程中，锰簇中引入了一分子水

Nature Communications

IF15.7

2026-08-22

OAAI

Asmit Bhowmick; Miao Zhang; Philipp S. Simon; Hiroki Makita; Isabela I. Nangca; Erzsi Szilagyi; Moritz Kretzschmar; Margaret D. Doyle; Natalie M. Minnetian; Rana Hussein; Olli Hart; Kuntal Chatterjee; A. Orkun Aydin; Dmitry Shevela; Mun Hon Cheah; Nicholas Croy; Petko Chernev; Thomas Fransson; Vandana Tiwari; Humberto Sanchez; Pamela Schleissner; Randy Lemons; Greg Gate; Meredith Henstridge; James M. Glownia; Frédéric Poitevin; Daniel J. Rosenberg; Sebastian Dehe; Leland B. Gee; Kensuke Tono; Shigeki Owada; Roland Oggenfuss; Dmitry Ozerov; Mathias Sander; Roman Mankowsky; Henrik T. Lemke; Iris D. Young; James M. Holton; David W. Mittan-Moreau; Daniel W. Paley; Pavel V. Afonine; Nigel W. Moriarty; Paul D. Adams; Fikret Mamedov; Holger Dobbek; Athina Zouni; Roberto Alonso-Mori; Uwe Bergmann; Aaron S. Brewster; Nicholas K. Sauter; Johannes Messinger; Jan F. Kern; Vittal K. Yachandra; Junko Yano

Report of high data rate macromolecular crystallography (HDRMX) meeting, 23 July 2025 高数据率大分子晶体学（HDRMX）会议报告，2025年7月23日

Structural Dynamics-US

IF2.3

2026-05-01

PREAI

Beavers, Christine; Bernstein, Herbert J.; Brewster, Aaron S.; Burian, Max; Devenish, Nicholas; Duan, Jiaxin Dawn; Eriksson, Daniel; Gamperle, Diego; Ha, Yang; Hall, David R.; Holton, James; Keller, Peter; Kroon-Batenburg, Loes; Mittan-Moreau, David W.; Nakaye, Yasukazu; Paley, Daniel W.; Peisach, Ezra; Sauter, Nicholas K.; Trampari, Sofia; Vonrhein, Clemens; Waterman, David G.; White, Thomas A.; Winter, Graeme

Testing the limits: serial crystallography using unpatterned fixed targets 测试极限: 使用未图案化的固定目标的串行晶体学

IUCRJ

IF3.6

2025-11-01

OAAI

Gorel, Alexander; Shoeman, Robert L.; Hartmann, Elisabeth; Nizinski, Stanislaw; Appleby, Martin V.; Beale, Emma V.; Dworkowski, Florian; Gotthard, Guillaume C.; Beale, John H.; Holton, James; Doak, R. Bruce; Barends, Thomas R. M.; Schlichting, Ilme

3D Nanocrystallography and the Imperfect Molecular Lattice

ANNUAL REVIEW OF PHYSICAL CHEMISTRY

IF11.7

2024-06-28

PREAI

Vlahakis, Niko; Holton, James; Sauter, Nicholas K.; Ercius, Peter; Brewster, Aaron S.; Rodriguez, Jose A.

Water Networks in Photosystem II Using Crystalline Molecular Dynamics Simulations and Room-Temperature XFEL Serial Crystallography

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-06-27

OAAI

Doyle, Margaret D. D.; Bhowmick, Asmit; Wych, David C. C.; Lassalle, Louise; Simon, Philipp S. S.; Holton, James; Sauter, Nicholas K. K.; Yachandra, Vittal K. K.; Kern, Jan F. F.; Yano, Junko; Wall, Michael E. E.

Large language models generate functional protein sequences across diverse families 大型语言模型生成跨不同家族的功能蛋白质序列

NATURE BIOTECHNOLOGY

IF41.7

2023-01-26

304

OAAI

Madani, Ali; Ben Krause, Ben; Greene, Eric R.; Subramanian, Subu; Mohr, Benjamin P.; Holton, James M.; Olmos, Jose Luis; Xiong, Caiming; Sun, Zachary Z. Z.; Socher, Richard; Fraser, James S.; Naik, Nikhil

The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature

SCIENCE ADVANCES

IF12.5

2022-05-27

OAAI

Correy, Galen J.; Kneller, Daniel W.; Phillips, Gwyndalyn; Pant, Swati; Russi, Silvia; Cohen, Aina E.; Meigs, George; Holton, James M.; Gahbauer, Stefan; Thompson, Michael C.; Ashworth, Alan; Coates, Leighton; Kovalevsky, Andrey; Meilleur, Flora; Fraser, James S.

Structural dynamics in the water and proton channels of photosystem II during the S2 to S3 transition 在S2到S3过渡期间，光系统II的水和质子通道中的结构动力学

NATURE COMMUNICATIONS

IF15.7

2021-11-11

OAAI

Hussein, Rana; Ibrahim, Mohamed; Bhowmick, Asmit; Simon, Philipp S.; Chatterjee, Ruchira; Lassalle, Louise; Doyle, Margaret; Bogacz, Isabel; Kim, In-Sik; Cheah, Mun Hon; Gul, Sheraz; de Lichtenberg, Casper; Chernev, Petko; Pham, Cindy C.; Young, Iris D.; Carbajo, Sergio; Fuller, Franklin D.; Alonso-Mori, Roberto; Batyuk, Alex; Sutherlin, Kyle D.; Brewster, Aaron S.; Bolotovsky, Robert; Mendez, Derek; Holton, James M.; Moriarty, Nigel W.; Adams, Paul D.; Bergmann, Uwe; Sauter, Nicholas K.; Dobbek, Holger; Messinger, Johannes; Zouni, Athina; Kern, Jan; Yachandra, Vittal K.; Yano, Junko

Clear evidence of binding of Ox to the oxygen-evolving complex of photosystem II is best observed in the omit map 在省略图中最好观察到Ox与光系统II的析氧复合物结合的明确证据

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-06-11

OAAI

Ibrahim, Mohamed; Moriarty, Nigel W.; Kern, Jan; Holton, James M.; Brewster, Aaron S.; Bhowmick, Asmit; Bergmann, Uwe; Zouni, Athina; Messinger, Johannes; Yachandra, Vittal K.; Yano, Junko; Dobbek, Holger; Sauter, Nicholas K.; Adams, Paul D.

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

SCIENCE ADVANCES

IF12.5

2021-04-16

102

OAAI

Schuller, Marion; Correy, Galen J.; Gahbauer, Stefan; Fearon, Daren; Wu, Taiasean; Diaz, Roberto Efrain; Young, Iris D.; Martins, Luan Carvalho; Smith, Dominique H.; Schulze-Gahmen, Ursula; Owens, Tristan W.; Deshpande, Ishan; Merz, Gregory E.; Thwin, Aye C.; Biel, Justin T.; Peters, Jessica K.; Moritz, Michelle; Herrera, Nadia; Kratochvil, Huong T.; Aimon, Anthony; Bennett, James M.; Neto, Jose Brandao; Cohen, Aina E.; Dias, Alexandre; Douangamath, Alice; Dunnett, Louise; Fedorov, Oleg; Ferla, Matteo P.; Fuchs, Martin R.; Gorrie-Stone, Tyler J.; Holton, James M.; Johnson, Michael G.; Krojer, Tobias; Meig, George; Powell, Ailsa J.; Rack, Johannes Gregor Matthias; Rangel, Victor L.; Russi, Silvia; Skyner, Rachael E.; Smith, Clyde A.; Soares, Alexei S.; Wierman, Jennifer L.; Zhu, Kang; O'Brien, Peter; Jura, Natalia; Ashworth, Alan; Irwin, John J.; Thompson, Michael C.; Gestwicki, Jason E.; von Delft, Frank; Shoichet, Brian K.; Fraser, James S.; Ahel, Ivan

Untangling the sequence of events during the S2 → S3 transition in photosystem II and implications for the water oxidation mechanism

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-05-20

175

OAAI

Ibrahim, Mohamed; Fransson, Thomas; Chatterjee, Ruchira; Cheah, Mun Hon; Hussein, Rana; Lassalle, Louise; Sutherlin, Kyle D.; Young, Iris D.; Fuller, Franklin D.; Gul, Sheraz; Kim, In-Sik; Simon, Philipp S.; de Lichtenberg, Casper; Chernev, Petko; Bogacz, Isabel; Pham, Cindy C.; Orville, Allen M.; Saichek, Nicholas; Northen, Trent; Batyuk, Alexander; Carbajo, Sergio; Alonso-Mori, Roberto; Tono, Kensuke; Owada, Shigeki; Bhowmick, Asmit; Bolotovsky, Robert; Mendez, Derek; Moriarty, Nigel W.; Holton, James M.; Dobbek, Holger; Brewster, Aaron S.; Adams, Paul D.; Sauter, Nicholas K.; Bergmann, Uwe; Zouni, Athina; Messinger, Johannes; Kern, Jan; Yachandra, Vittal K.; Yano, Junko

Radiation damage and dose limits in serial synchrotron crystallography at cryo- and room temperatures 低温和室温下串行同步加速器晶体学中的辐射损伤和剂量限制

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-02-11

OAAI

de la Mora, Eugenio; Coquelle, Nicolas; Bury, Charles S.; Rosenthal, Martin; Holton, James M.; Carmichael, Ian; Garman, Elspeth F.; Burghammer, Manfred; Colletier, Jacques-Philippe; Weik, Martin

Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite

CELL CHEMICAL BIOLOGY

IF7.2

2019-05-01

OAAI

Bruning, John M.; Wang, Yan; Oltrabella, Francesca; Tian, Boxue; Kholodar, Svetlana A.; Liu, Harrison; Bhattacharya, Paulomi; Guo, Su; Holton, James M.; Fletterick, Robert J.; Jacobson, Matthew P.; England, Pamela M.

Structuring of Hydrogels across Multiple Length Scales for Biomedical Applications 用于生物医学应用的跨多个长度尺度的水凝胶的结构化

ADVANCED MATERIALS

IF26.8

2018-02-12

OAAI

Cooke, Megan E.; Jones, Simon W.; ter Horst, Britt; Moiemen, Naiem; Snow, Martyn; Chouhan, Gurpreet; Hill, Lisa J.; Esmaeli, Maryam; Moakes, Richard J. A.; Holton, James; Nandra, Rajpal; Williams, Richard L.; Smith, Alan M.; Grover, Liam M.

Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2017-09-11

138

OAAI

Knott, Gavin J.; East-Seletsky, Alexandra; Cofsky, Joshua C.; Holton, James M.; Charles, Emeric; O'Connell, Mitchell R.; Doudna, Jennifer A.

Selenium single-wavelength anomalous diffraction de novo phasing using an X-ray-free electron laser

NATURE COMMUNICATIONS

IF15.7

2016-11-04

OAAI

Hunter, Mark S.; Yoon, Chun Hong; DeMirci, Hasan; Sierra, Raymond G.; Dao, E. Han; Ahmadi, Radman; Aksit, Fulya; Aquila, Andrew L.; Ciftci, Halilibrahim; Guillet, Serge; Hayes, Matt J.; Lane, Thomas J.; Liang, Meng; Lundstrom, Ulf; Koglin, Jason E.; Mgbam, Paul; Rao, Yashas; Zhang, Lindsey; Wakatsuki, Soichi; Holton, James M.; Boutet, Sebastien

Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1 / SNARE complex

ELIFE

IF0

2016-10-12

OAAI

Lyubimov, Artem Y.; Uervirojnangkoorn, Monarin; Zeldin, Oliver B.; Zhou, Qiangjun; Zhao, Minglei; Brewster, Aaron S.; Michels-Clark, Tara; Holton, James M.; Sauter, Nicholas K.; Weis, William I.; Brunger, Axel T.

Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography

ELIFE

IF0

2015-09-30

149

OAAI

Keedy, Daniel A.; Kenner, Lillian R.; Warkentin, Matthew; Woldeyes, Rahel A.; Hopkins, Jesse B.; Thompson, Michael C.; Brewster, Aaron S.; Van Benschoten, Andrew H.; Baxter, Elizabeth L.; Uervirojnangkoorn, Monarin; McPhillips, Scott E.; Song, Jinhu; Alonso-Mori, Roberto; Holton, James M.; Weis, William I.; Brunger, Axel T.; Soltis, S. Michael; Lemke, Henrik; Gonzalez, Ana; Sauter, Nicholas K.; Cohen, Aina E.; van den Bedem, Henry; Thorne, Robert E.; Fraser, James S.

Macromolecular X-ray structure determination using weak, single-wavelength anomalous data

NATURE METHODS

IF32.1

2014-12-22

OAAI

Bunkoczi, Gabor; Mccoy, Airlie J.; Echols, Nathaniel; Grosse-Kunstleve, Ralf W.; Adams, Paul D.; Holton, James M.; Read, Randy J.; Terwilliger, Thomas C.

Goniometer-based femtosecond crystallography with X-ray free electron lasers

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-10-31

123

OAAI

Cohen, Aina E.; Soltis, S. Michael; Gonzalez, Ana; Aguila, Laura; Alonso-Mori, Roberto; Barnes, Christopher O.; Baxter, Elizabeth L.; Brehmer, Winnie; Brewster, Aaron S.; Brunger, Axel T.; Calero, Guillermo; Chang, Joseph F.; Chollet, Matthieu; Ehrensberger, Paul; Eriksson, Thomas L.; Feng, Yiping; Hattne, Johan; Hedman, Britt; Hollenbeck, Michael; Holton, James M.; Keable, Stephen; Kobilka, Brian K.; Kovaleva, Elena G.; Kruse, Andrew C.; Lemke, Henrik T.; Lin, Guowu; Lyubimov, Artem Y.; Manglik, Aashish; Mathews, Irimpan I.; McPhillips, Scott E.; Nelson, Silke; Peters, John W.; Sauter, Nicholas K.; Smith, Clyde A.; Song, Jinhu; Stevenson, Hilary P.; Tsai, Yingssu; Uervirojnangkoorn, Monarin; Vinetsky, Vladimir; Wakatsuki, Soichi; Weis, William I.; Zadvornyy, Oleg A.; Zeldin, Oliver B.; Zhu, Diling; Hodgson, Keith O.

研究方向