Carrie K. Jones - Publications, H-index & Citations

Carrie K. Jones

vanderbilt university

53H指数

271论文数

8.6K被引数

收录论文 107

发表时间

Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent; Selective; and CNS-Penetrant Agonists for the Cannabinoid Receptor 2

Journal of Medicinal Chemistry

IF6.8

2026-02-05

OAAI

Daniel H. Haymer; Renn A. Duncan; Alice L. Rodriguez; Allie Han; Richard J. Lindsay; N. Kithmini Wijesiri; Analisa Thompson Gray; Srinivasan Krishnan; Aidong Qi; Benjamin P. Brown; Olivier Boutaud; Darren W. Engers; Carrie K. Jones; Colleen M. Niswender; Craig W. Lindsley; Aaron M. Bender

Discovery of VU6052254: A Novel; Potent M1 Positive Allosteric Modulator VU6052254的发现：一种新型的强效M1正向别构调节剂

ACS Chemical Neuroscience

IF3.9

2025-11-26

OAAI

Julie L. Engers; Joseph D. Bungard; Christopher C. Presley; Irene Zagol-Ikapitte; Katherine J. Watson; Sichen Chang; Colin O’Carroll; P. Markus Dey; Ethan S. Burstein; Jonathan W. Dickerson; Analisa Thompson Gray; Michael Bubser; Jerri M. Rook; Hyekyung P. Cho; Valerie M. Kramlinger; Olivier Boutaud; Carrie K. Jones; P. Jeffrey Conn; Darren W. Engers; Craig W. Lindsley

Optimization of Selective and CNS Penetrant Alkyne-Based TREK Inhibitors: The Discovery and Characterization of ONO-9517601 (VU6022856) and ONO-7927846 (VU6024391)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-10-01

PREAI

Tanaka, Motoyuki; Sekioka, Yoko; Hashimoto, Gakuji; Mori, Takahiro; Shono, Tomoyuki; Isaji, Yuuki; Hisaichi, Katsuya; Childress, Elizabeth S.; Bollinger, Sean; Schmitt, Joza A.; Chopko, Trevor C.; Garrison, Aaron T.; Perry, Charles K.; Chronister, Keagan; Kramer, Meghan; Chang, Sichen; Watson, Katherine J.; Dickerson, Jonathan W.; Bubser, Michael; Rook, Jerri M.; Jones, Carrie K.; Boutaud, Olivier; Bridges, Thomas M.; Denton, Jerod S.; Engers, Darren W.; Kurata, Haruto; Lindsley, Craig W.

THE DEVELOPMENT OF DRUGS TO ACTIVATE THE MUSCARINIC M1 AND M4 RECEPTORS TO TREAT DISORDERS OF THE HUMAN CNS

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

IF3.7

2025-08-01

OAAI

Jones, C. K.

Shank3 modulates Rpl3 expression and protein synthesis via mGlu5: implications for Phelan McDermid syndrome Shank3通过mGlu5调节Rpl3的表达和蛋白质合成：对Phelan McDermid综合征的启示

MOLECULAR PSYCHIATRY

IF10.1

2025-03-15

OAAI

Giona, Federica; Beretta, Stefania; Zippo, Antonio; Stefanoni, Alessia; Tomasoni, Zaira; Vicidomini, Cinzia; Ponzoni, Luisa; Sala, Mariaelvina; Jones, Carrie K.; Conn, P. Jeffrey; Boeckers, Tobias M.; Sala, Carlo; Verpelli, Chiara

Discovery of VU0467319: an M1 Positive Allosteric Modulator Candidate That Advanced into Clinical Trials

ACS CHEMICAL NEUROSCIENCE

IF3.9

2024-12-11

OAAI

Poslunsey, Michael S.; Wood, Michael R.; Han, Changho; Stauffer, Shaun R.; Panarese, Joseph D.; Melancon, Bruce J.; Engers, Julie L.; Dickerson, Jonathan W.; Peng, Weimin; Noetzel, Meredith J.; Cho, Hyekyung P.; Rodriguez, Alice L.; Hopkins, Corey R.; Morrison, Ryan; Crouch, Rachel D.; Bridges, Thomas M.; Blobaum, Anna L.; Boutaud, Olivier; Daniels, J. Scott; Kates, Michael J.; Castelhano, Arlindo; Rook, Jerri M.; Niswender, Colleen M.; Jones, Carrie K.; Conn, P. Jeffrey; Lindsley, Craig W.

Discovery of 4-(5-Membered)Heteroarylether-6-methylpicolinamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2024-11-18

OAAI

Childress, Elizabeth S.; Capstick, Rory A.; Crocker, Katherine E.; Ledyard, Miranda L.; Bender, Aaron M.; Maurer, Mallory A.; Billard, Natasha B.; Cho, Hyekyung P.; Rodriguez, Alice L.; Niswender, Colleen M.; Peng, Weimin; Rook, Jerri M.; Chang, Sichen; Blobaum, Anna L.; Boutaud, Olivier; Thompson Gray, Analisa; Jones, Carrie K.; Conn, P. Jeffrey; Felts, Andrew S.; Lindsley, Craig W.; Temple, Kayla J.

Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM)

ACS CHEMICAL NEUROSCIENCE

IF3.9

2024-09-24

OAAI

Engers, Julie L.; Baker, Logan A.; Chang, Sichen; Luscombe, Vincent B.; Rodriguez, Alice L.; Niswender, Colleen M.; Cho, Hyekyung P.; Bubser, Michael; Gray, Analisa Thompson; Jones, Carrie K.; Peng, Weimin; Rook, Jerri M.; Bridges, Thomas M.; Boutaud, Olivier; Conn, P. Jeffrey; Engers, Darren W.; Lindsley, Craig W.; Temple, Kayla J.

Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M5 Muscarinic Acetylcholine Receptor

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-08-06

OAAI

Li, Jinming; Orsi, Douglas L.; Engers, Julie L.; Long, Madeline F.; Capstick, Rory A.; Maurer, Mallory A.; Presley, Christopher C.; Vinson, Paige N.; Rodriguez, Alice L.; Han, Allie; Cho, Hyekyung P.; Chang, Sichen; Jackson, Megan; Bubser, Michael; Blobaum, Anna L.; Boutaud, Olivier; Nader, Michael A.; Niswender, Colleen M.; Conn, P. Jeffrey; Jones, Carrie K.; Lindsley, Craig W.; Han, Changho

Evaluation of the Indazole Analogs of 5-MeO-DMT and Related Tryptamines as Serotonin Receptor 2 Agonists

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2024-01-19

OAAI

Jayakodiarachchi, Navoda; Maurer, Mallory A.; Schultz, Daniel C.; Dodd, Cayden J.; Gray, Analisa Thompson; Cho, Hyekyung P.; Boutaud, Olivier; Jones, Carrie K.; Lindsley, Craig W.; Bender, Aaron M.

M1-selective muscarinic allosteric modulation enhances cognitive flexibility and effective salience in nonhuman primates

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-04-27

OAAI

Hassani, Seyed A.; Neumann, Adam; Russell, Jason; Jones, Carrie K.; Womelsdorf, Thilo

M1/M4-Preferring Muscarinic Cholinergic Receptor Agonist Xanomeline Reverses Wake and Arousal Deficits in Nonpathologically Aged Mice

ACS CHEMICAL NEUROSCIENCE

IF3.9

2023-01-19

OAAI

Russell, Jason K.; Ingram, Shalonda M.; Teal, Laura B.; Lindsley, Craig W.; Jones, Carrie K.

Development of VU6019650: A Potent, Highly Selective, andSystemically Active Orthosteric Antagonist of the M5MuscarinicAcetylcholine Receptor for the Treatment of Opioid Use Disorder

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-04-13

PREAI

Garrison, Aaron T.; Orsi, Douglas L.; Capstick, Rory A.; Whomble, David; Li, Jinming; Carter, Trever R.; Felts, Andrew S.; Vinson, Paige N.; Rodriguez, Alice L.; Han, Allie; Hajari, Krishma; Cho, Hyekyung P.; Teal, Laura B.; Ragland, Madeline G.; Ghamari-Langroudi, Masoud; Bubser, Michael; Chang, Sichen; Schnetz-Boutaud, Nathalie C.; Boutaud, Olivier; Blobaum, Anna L.; Foster, Daniel J.; Niswender, Colleen M.; Conn, P. Jeffrey; Lindsley, Craig W.; Jones, Carrie K.; Han, Changho

Partial mGlu5 Negative Allosteric Modulator M-5MPEP Demonstrates Antidepressant-Like Effects on Sleep Without Affecting Cognition or Quantitative EEG 部分mGlu5负性变构调节剂M-5MPEP对睡眠表现出抗抑郁样作用，而不影响认知或定量脑电图

FRONTIERS IN NEUROSCIENCE

IF3.2

2021-07-02

OAAI

Holter, Kimberly M.; Lekander, Alex D.; LaValley, Christina M.; Bedingham, Elizabeth G.; Pierce, Bethany E.; Sands, L. Paul; Lindsley, Craig W.; Jones, Carrie K.; Gould, Robert W.

Acetylcholine Muscarinic M4 Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents

BIOLOGICAL PSYCHIATRY

IF9

2020-12-01

OAAI

Walker, Leigh C.; Berizzi, Alice E.; Chen, Nicola A.; Rueda, Patricia; Perreau, Victoria M.; Huckstep, Katherine; Srisontiyakul, Jirawoot; Govitrapong, Piyarat; Jia Xiaojian; Lindsley, Craig W.; Jones, Carrie K.; Riddy, Darren M.; Christopoulos, Arthur; Langmead, Christopher J.; Lawrence, Andrew J.

Modulation of arousal and sleep/wake architecture by M1PAM VU0453595 across young and aged rodents and nonhuman primates

NEUROPSYCHOPHARMACOLOGY

IF7.1

2020-08-31

OAAI

Gould, Robert W.; Russell, Jason K.; Nedelcovych, Michael T.; Bubser, Michael; Blobaum, Anna L.; Bridges, Thomas M.; Newhouse, Paul A.; Lindsley, Craig W.; Conn, P. Jeffrey; Nader, Michael A.; Jones, Carrie K.

The Effects of the M1 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator VU0486846 on Cognitive Performance in Aged Nonhuman Primates

FASEB JOURNAL

IF4.2

2020-04-19

PREAI

Norman, Christina; Gould, Robert; Bragg, Chrystal; Lindsley, Craig; Jones, Carrie; Nader, Michael

Acute Negative Allosteric Modulation of M5 Muscarinic Acetylcholine Receptors Inhibits Oxycodone Self-Administration and Cue-Induced Reactivity with No Effect on Antinociception

ACS CHEMICAL NEUROSCIENCE

IF3.9

2019-07-03

OAAI

Gould, Robert W.; Gunter, Barak W.; Bubser, Michael; Matthews, Robert T.; Teal, Laura B.; Ragland, Madeline G.; Bridges, Thomas M.; Garrison, Aaron T.; Winder, Danny G.; Lindsley, Craig W.; Jones, Carrie K.

The Role of Estrogen in Brain and Cognitive Aging

NEUROTHERAPEUTICS

IF6.9

2019-07-01

145

OAAI

Russell, Jason K.; Jones, Carrie K.; Newhouse, Paul A.

Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain Models (vol 10, pg 1294, 2019)

ACS CHEMICAL NEUROSCIENCE

IF3.9

2019-03-26

PREAI

Abney, Kristopher K.; Bubser, Michael; Du, Yu; Kozek, Krystian A.; Bridges, Thomas M.; Lindsley, Craig W.; Daniels, J. Scott; Morrison, Ryan D.; Wickman, Kevin; Hopkins, Corey R.; Jones, Carrie K.; Weaver, C. David

研究方向