Yanling Wu - Publications, H-index & Citations

Yanling Wu

zhejiang provincial center for disease control & prevention

20H指数

51论文数

1.8K被引数

收录论文 25

发表时间

Design, synthesis, and evaluation of antitumor activity of 2-arylmethox-y-4-(2-fluoromethyl-biphenyl-3-ylmethoxy) benzylamine derivatives as PD-1/PD-l1 inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-10-01

PREAI

Zhang, Feng; Zhang, Hua; Zhou, Shijia; Plewka, Jacek; Wang, Ming; Sun, Shishi; Wu, Caiyun; Yu, Qimeng; Zhu, Mengyu; Awadasseid, Annoor; Wu, Yanling; Magiera-Mularz, Katarzyna; Zhang, Wen

Small molecule and PROTAC molecule experiments in vitro and in vivo, focusing on mouse PD-L1 and human PD-L1 differences as targets

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2024-03-01

OAAI

Awadasseid, Annoor; Wang, Rui; Sun, Shishi; Zhang, Feng; Wu, Yanling; Zhang, Wen

Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2,2′-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-07-26

PREAI

Zhang, Hua; Zhou, Shijia; Plewka, Jacek; Wu, Caiyun; Zhu, Mengyu; Yu, Qimeng; Musielak, Bogdan; Wang, Xiao; Awadasseid, Annoor; Magiera-Mularz, Katarzyna; Wu, Yanling; Zhang, Wen

PD-L1 dimerisation induced by biphenyl derivatives mediates anti-breast cancer activity via the non-immune PD-L1-AKT-mTOR/Bcl2 pathway

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2023-07-13

OAAI

Zhang, Hua; Zhou, Shi-Jia; Shen, Chen-Feng; Zhou, Yong-Nan; Wu, Cai-Yun; Zhu, Meng-Yu; Yu, Qi-Meng; Awadasseid, Annoor; Wu, Yan-Ling; Zhang, Wen

Artificial intelligence in cancer immunotherapy: Applications in neoantigen recognition, antibody design and immunotherapy response prediction

SEMINARS IN CANCER BIOLOGY

IF15.7

2023-06-01

PREAI

Li, Tong; Li, Yupeng; Zhu, Xiaoyi; He, Yao; Wu, Yanling; Ying, Tianlei; Xie, Zhi

Current studies and future promises of PD-1 signal inhibitors in cervical cancer therapy PD-1信号抑制剂在宫颈癌治疗中的研究现状及展望

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2023-01-01

OAAI

Awadasseid, Annoor; Zhou, Yongnan; Zhang, Koutian; Tian, Kaiming; Wu, Yanling; Zhang, Wen

Design, synthesis and bioactivity of novel naphthalimide-benzotriazole conjugates against A549 cells via targeting BCL2 G-quadruplex and inducing autophagy

LIFE SCIENCES

IF5.1

2022-08-01

PREAI

Wang, Xiao; Zhang, Mi; Xiong, Xu-Qiong; Yang, Hao; Wang, Panpan; Zhang, Koutian; Awadasseid, Annoor; Narva, Suresh; Wu, Yan-Ling; Zhang, Wen

Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex

BIOCHEMICAL PHARMACOLOGY

IF5.6

2022-07-01

PREAI

Huang, Qiong; Wang, Xiao; Chen, An; Zhang, Hua; Yu, Qimeng; Shen, Chenfeng; Awadasseid, Annoor; Zhao, Xiaoyin; Xiong, Xuqiong; Wu, Yanling; Zhang, Wen

Genetic variants in choline metabolism pathway are associated with the risk of bladder cancer in the Chinese population

ARCHIVES OF TOXICOLOGY

IF6.9

2022-03-03

PREAI

Han, Zhichao; Gu, Jingjing; Xin, Junyi; Liu, Hanting; Wu, Yanling; Du, Mulong; Chu, Haiyan; Liu, Yadong; Zhang, Zhengdong

Potential protective role of the anti-PD-1 blockade against SARS-CoV-2 infection

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2021-10-01

OAAI

Awadasseid, Annoor; Yin, Qiang; Wu, Yanling; Zhang, Wen

Advance investigation on synthetic small-molecule inhibitors targeting PD-1/PD-L1 signaling pathway 靶向PD-1/PD-L1信号通路的合成小分子抑制剂研究进展

LIFE SCIENCES

IF5.1

2021-10-01

PREAI

Awadasseid, Annoor; Wu, Yanling; Zhang, Wen

Extracellular Vesicles (Exosomes) as Immunosuppressive Mediating Variables in Tumor and Chronic Inflammatory Microenvironments

CELLS

IF5.2

2021-09-24

OAAI

Awadasseid, Annoor; Wu, Yanling; Zhang, Wen

G-quadruplex stabilization via small-molecules as a potential anti-cancer strategy

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2021-07-01

OAAI

Awadasseid, Annoor; Ma, Xudong; Wu, Yanling; Zhang, Wen

Discovery of Pyrrole-imidazole Polyamides as PD-L1 Expression Inhibitors and Their Anticancer Activity via Immune and Nonimmune Pathways

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-05-05

PREAI

Wang, Ming; Ma, Xudong; Zhou, Kang; Mao, Huijuan; Liu, Jiachun; Xiong, Xuqiong; Zhao, Xiaoyin; Narva, Suresh; Tanaka, Yoshimasa; Wu, Yanling; Guo, Chuanxin; Sugiyama, Hiroshi; Zhang, Wen

Effect of 4,5-diazafluorene derivative on γδ T cell-mediated cytotoxicity against renal cell carcinoma

LIFE SCIENCES

IF5.1

2021-03-01

PREAI

Wen, Xiaolan; Wu, Yanling; Tanaka, Yoshimasa; Awadasseid, Annoor; Tao, Houquan; Zhang, Wen

Design, synthesis and anti-cancer activity of pyrrole-imidazole polyamides through target-downregulation of c-kit gene expression

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-12-01

PREAI

Zhang, Mi; Liang, Jing; Jiang, Shi-Kun; Xu, Ling; Wu, Yan-Ling; Awadasseid, Annoor; Zhao, Xiao-Yin; Xiong, Xu-Qiong; Sugiyama, Hiroshi; Zhang, Wen

Anti-cancer activity of benzoxazinone derivatives via targeting c-Myc G-quadruplex structure

LIFE SCIENCES

IF5.1

2020-10-01

PREAI

Jiang, Shikun; Awadasseid, Annoor; Narva, Suresh; Cao, Song; Tanaka, Yoshimasa; Wu, Yanling; Fu, Wei; Zhao, Xiaoyin; Wei, Chuanhe; Zhang, Wen

Synthesis and Evaluation of Biphenyl-1,2,3-Triazol-Benzonitrile Derivatives as PD-1/PD-L1 Inhibitors

ACS OMEGA

IF4.3

2020-08-14

OAAI

Narva, Suresh; Xiong, Xuqiong; Ma, Xudong; Tanaka, Yoshimasa; Wu, Yanling; Zhang, Wen

Design, synthesis of 4,5-diazafluorene derivatives and their anticancer activity via targeting telomeric DNA G-quadruplex 4，5-二氮芴衍生物的设计、合成及其靶向端粒DNA G-四链体的抗癌活性

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-09-01

PREAI

Zhou, Kang; Liu, Jiachun; Xiong, Xuqiong; Cheng, Mei; Hu, Xiaolin; Narva, Suresh; Zhao, Xiaoyin; Wu, Yanling; Zhang, Wen

Angiotensin I-converting enzyme inhibitory peptides from Sipuncula (Phascolosoma esculenta): Purification, identification, molecular docking and antihypertensive effects on spontaneously hypertensive rats

PROCESS BIOCHEMISTRY

IF4

2017-12-01

PREAI

Guo, Mingrong; Chen, Xujun; Wu, Yanling; Zhang, Lujia; Huang, Weixue; Yuan, Ying; Fang, Ming; Xie, Jingli; Wei, Dongzhi

研究方向