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收藏A novel first-in-class USP19 inhibitor for the treatment of cancer-induced muscle atrophy
Page, Natalie; Karthikaisamy, Vignesh; O'Hara, Darren; Cranston, Aaron N.; O'Dowd, Colin R.; Jacq, Xavier; Wilkinson, Richard; Burton, Stephanie; Gibson, Hayley; Costa, Joana; Longley, Daniel; Helm, Matthew; McGivern, Chris; Shepherd, Steven; Bell, Christina; Hewitt, Peter; McFarland, Mary; Miel, Hugues; Whitehead, Steven; Proctor, Lauren; Rountree, Shane J.; Wappett, Mark; Diaz, Mauricio Berriel; Herzig, Stephan; Harrison, Timothy
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收藏Targeting the ubiquitin-proteasome system by small molecule inhibition of the DUBome
Harrison, Tim; Jacq, Xavier; O'Dowd, Colin; Gavory, Gerald; Barker, Oliver; Bell, Christina; Burkamp, Frank; Burton, Stephanie; Cassidy, Eamon; Helm, Matthew; Hewitt, Peter; Page, Natalie; Rountree, Shane; Rozycka, Ewelina; Shepherd, Steven; Whitehead, Steven; Wappett, Mark
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收藏Accessing the cancer DUBome with UbiPlex: A bespoke drug discovery platform for deubiquitinase enzymes
Gavory, Gerald; O'Dowd, Colin; Barker, Oliver; Bell, Christina; Burkamp, Frank; Burton, Stephanie; Cassidy, Eamon; Costa, Joana; Dossang, Anthony; Helm, Matt; Henderson, Ashling; Hewitt, Peter; Hughes, Caroline; McFarland, Mary; Miel, Hugues; Page, Natalie; Proctor, Lauren; Rountree, Shane; Rozycka, Ewelina; Shepherd, Steven; Treder, Adam; Wappett, Mark; Whitehead, Steven; Harrison, Tim
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收藏Development and characterization of ADC999: A novel, potent orally available Wee1 inhibitor with robust antitumor efficacy in vivo
Gavory, Gerald; O'Dowd, Colin; Rozycka, Ewelina; Boyd, Caroline; Gorges, Beronia; McLean, Estelle; Daubriac, Julien; Rountree, Shane; Shepherd, Steven; Burton, Stephanie; McFarland, Mary; Treder, Adam; Wilkinson, Andy; Burkamp, Frank; Harrison, Tim
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收藏A novel, potent and selective inhibitor of Wee1 with robust antitumor activity in various cancer xenograph models
Gavory, Gerald; O'Dowd, Colin; Burkamp, Frank; Rountree, Shane; Rozycka, Ewelina; Boyd, Caroline; Gorges, Beronia; Burton, Stephanie; Wilkinson, Andy; Shepherd, Steven; Janssen, Dominic; McFarland, Mary; Rountree, Shane; Harrison, Tim
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