Wannian Zhang - Publications, H-index & Citations

Wannian Zhang

Naval Medical University

36H指数

154论文数

4.0K被引数

收录论文 78

发表时间

Structure-based molecular hybridization design and synthesis of Keap1-Nrf2 inhibitors for anti-inflammatory treatment 基于结构的分子杂交设计及抗炎治疗用Keap1-Nrf2抑制剂的合成

BIOORGANIC CHEMISTRY

IF4.7

2025-05-01

PREAI

Qin, Xiuting; Hou, Ruilin; Qu, Zhuo; Yu, Jianqiang; Zhang, Wannian; Ma, Hao; Zhuang, Chunlin

Labeled and Label-Free Target Identifications of Natural Products

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-10-03

PREAI

Wang, Shuyu; Zhang, Yu; Yu, Ruizhi; Chai, Yue; Liu, Ruyun; Yu, Jianqiang; Qu, Zhuo; Zhang, Wannian; Zhuang, Chunlin

Discovery of Sophoridine α-Aryl Propionamide Derivative ZM600 as a Novel Antihepatic Fibrosis Agent

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-06-28

PREAI

Li, Guoqing; Lu, Juanni; Wang, Chuanhao; Chang, Xuliang; Qu, Zhuo; Zhang, Wannian; Zhuang, Chunlin; Miao, Zhenyuan; Xu, Weiheng

Real-Time Adaptive Energy Management for Hybrid Electric Vehicles Based on Monte Carlo Tree Search 基于蒙特卡洛树搜索的混合动力汽车实时自适应能量管理

IEEE TRANSACTIONS ON TRANSPORTATION ELECTRIFICATION

IF8.3

2024-06-01

PREAI

Yang, Ningkang; Han, Lijin; Ruan, Shumin; Zhang, Wannian; Liu, Hui; Xiang, Changle

Pharmacokinetic, Tissue Distribution, Metabolite, and Toxicity Evaluation of the Matrine Derivative, (6aS, 10S, 11aR, 11bR, 11cS)-10-Methylaminododecahydro-3a, 7a-Diaza-benzo (de) Anthracene-8-thione

MOLECULES

IF4.6

2024-01-06

OAAI

Li, Liuyan; Lu, Fangfang; Ding, Shuqin; Wang, Xiaoying; Wang, Weibiao; Zhang, Wannian; Xu, Weiheng; Zhuang, Chunlin; Miao, Zhenyuan; Ma, Xueqin

Diallyl trisulfide inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung cancer via modulating gut microbiota and the PPARγ/NF-κB pathway

FOOD & FUNCTION

IF5.4

2024-01-01

PREAI

Qu, Zhuo; Tian, Jiahui; Sun, Jiachen; Shi, Ying; Yu, Jianqiang; Zhang, Wannian; Zhuang, Chunlin

Diallyl Disulfide Blocks Cigarette Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced Lung Tumorigenesis via Activation of the Nrf2 Antioxidant System and Suppression of NF-κB Inflammatory Response

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

IF6.2

2023-11-13

PREAI

Tian, Jiahui; Zhao, Wenli; Wu, Yanran; Shi, Ying; Yu, Jianqiang; Zhang, Wannian; Xing, Chengguo; Zhuang, Chunlin; Qu, Zhuo

Receptor-interacting protein kinase 1 (RIPK1) inhibitor: a review of the patent literature (2018-present)受体相互作用蛋白激酶1 (RIPK1) 抑制剂: 专利文献综述 (2018)

EXPERT OPINION ON THERAPEUTIC PATENTS

IF4.6

2023-03-28

PREAI

Xu, Lijuan; Zhang, Wannian; Zhuang, Chunlin

Targeting Receptor-Interacting Protein Kinase 1 by Novel Benzothiazole Derivatives: Treatment of Acute Lung Injury through the Necroptosis Pathway

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-03-13

PREAI

Zhang, Xinqi; Han, Qianyu; Hou, Ruilin; Xu, Lijuan; Zhang, Wannian; Xing, Chengguo; Xue, Lei; Zhuang, Chunlin

Structure-Based Design of Novel Alkynyl Thio-Benzoxazepinone Receptor-Interacting Protein Kinase-1 Inhibitors: Extending the Chemical Space from the Allosteric to ATP Binding Pockets

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-02-01

PREAI

Quan, Danni; Hou, Ruilin; Shao, Hongming; Zhang, Xinqi; Yu, Jianqiang; Zhang, Wannian; Yuan, Hongbin; Zhuang, Chunlin

Roxarsone inhibits hepatic stellate cell activation and ameliorates liver fibrosis by blocking TGF-β1/Smad signaling pathway Roxarsone通过阻断TGF-β1/Smad信号通路抑制肝星状细胞活化并改善肝纤维化

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2023-01-01

PREAI

Li, Ting-Ting; Su, Xiao-Wei; Chen, Lin-Lin; Zhang, Wan-Nian; Zhang, Jun-Ping; Wang, Yan; Xu, Wei-Heng

JMJD4-demethylated RIG-I prevents hepatic steatosis and carcinogenesis

JOURNAL OF HEMATOLOGY & ONCOLOGY

IF40.4

2022-11-04

OAAI

Li, Zhenyang; Zhou, Ye; Jia, Kaiwei; Yang, Yingyun; Zhang, Liyuan; Wang, Suyuan; Dong, Yue; Wang, Mu; Li, Yunhui; Lu, Shan; Zhang, Wannian; Zhang, Luxin; Fan, Yiwen; Zhang, Dingji; Li, Nan; Yu, Yizhi; Cao, Xuetao; Hou, Jin

Discovery of a Trifluoromethoxy Cyclopentanone Benzothiazole Receptor-Interacting Protein Kinase 1 Inhibitor as the Treatment for Alzheimer's Disease

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-10-26

PREAI

Sun, Yi; Xu, Lijuan; Shao, Hongming; Quan, Danni; Mo, Zixin; Wang, Jue; Zhang, Wannian; Yu, Jianqiang; Zhuang, Chunlin; Xu, Ke

Investigation on the chemical space of the substituted triazole thio-benzoxazepinone RIPK1 inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-06-01

PREAI

Hao, Yanan; Shao, Hongming; Qu, Zhuo; Li, Jiao; Shi, Ying; Zhang, Wannian; Yu, Jianqiang; Fu, Peng; Zhuang, Chunlin

Targeting Necroptosis as a Promising Therapy for Alzheimer's Disease 针对坏死性凋亡作为阿尔茨海默氏病的有希望的治疗方法

ACS CHEMICAL NEUROSCIENCE

IF3.9

2022-05-24

PREAI

Zhao, Wenli; Liu, Yue; Xu, Lijuan; He, Yuan; Cai, Zhenyu; Yu, Jianqiang; Zhang, Wannian; Xing, Chengguo; Zhuang, Chunlin; Qu, Zhuo

Structure-based optimizations of a necroptosis inhibitor (SZM594) as novel protective agents of acute lung injury

CHINESE CHEMICAL LETTERS

IF8.9

2022-05-01

PREAI

Xu, Lijuan; Tu, Ye; Li, Jiao; Zhang, Wannian; Wang, Zhibin; Zhuang, Chunlin; Xue, Lei

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7-acetylated and cytoplasm-translocated G protein GαS

HEPATOLOGY

IF15.8

2022-04-11

OAAI

Zhou, Ye; Jia, Kaiwei; Wang, Suyuan; Li, Zhenyang; Li, Yunhui; Lu, Shan; Yang, Yingyun; Zhang, Liyuan; Wang, Mu; Dong, Yue; Zhang, Luxin; Zhang, Wannian; Li, Nan; Yu, Yizhi; Cao, Xuetao; Hou, Jin

Peramivir, an Anti-Influenza Virus Drug, Exhibits Potential Anti-Cytokine Storm Effects

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-02-28

OAAI

Zhang, Chen-xi; Tu, Ye; Sun, Xiao-chen; Chen, Da-gui; Zhang, Wan-nian; Zhuang, Chun-lin; Wang, Zhi-bin; Su, Li

Discovery of a Potent Botulinum Neurotoxin A Inhibitor ZM299 with Effective Protections in Botulism Mice

CHINESE JOURNAL OF CHEMISTRY

IF5.5

2021-12-19

PREAI

Wang, Jianxin; Wu, Yuelin; Luo, Deyan; Zhuang, Chunlin; Ning, Nianzhi; Zhang, Yanming; He, Zhili; Gao, Jie; Hong, Zhanying; Xv, Xiguo; Zhang, Wannian; Li, Tao; Miao, Zhenyuan; Wang, Hui

Garlic oil blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis by inducing phase II drug-metabolizing enzymes

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2021-11-01

PREAI

Zhang, Lei; Qu, Zhuo; Song, Aiwei; Yang, Jianhong; Yu, Jianqiang; Zhang, Wannian; Zhuang, Chunlin

研究方向