未登录 Safety, Pharmacokinetics and Target Engagement of a Novel Brain Penetrant RIPK1 Inhibitor (SIR9900) in Healthy Adults and Elderly Participants Gonen, Ofer Michael; Porter, Tim; Wang, Buwei; Xue, Fenchao; Ma, Yongfen; Song, Linan; Sun, Pei; Fan, Weiliang; Shen, Yang 分享 收藏
A phase I randomized study to evaluate safety, pharmacokinetics, and pharmacodynamics of SIR2446M, a selective RIPK1 inhibitor, in healthy participants Sun, Ana Liza Andresan; Gillies, John David; Shen, Yang; Deng, Huajun; Xue, Fenchao; Ma, Yongfen; Song, Linan 分享 收藏
Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration 血浆神经丝光可预测家族性额颞叶变性的疾病进展 Rojas, Julio C.; Wang, Ping; Staffaroni, Adam M.; Heller, Carolin; Cobigo, Yann; Wolf, Amy; Goh, Sheng-Yang M.; Ljubenkov, Peter A.; Heuer, Hilary W.; Fong, Jamie C.; Taylor, Joanne B.; Veras, Eliseo; Song, Linan; Jeromin, Andreas; Hanlon, David; Yu, Lili; Khinikar, Arvind; Sivasankaran, Rajeev; Kieloch, Agnieszka; Valentin, Marie-Anne; Karydas, Anna M.; Mitic, Laura L.; Pearlman, Rodney; Kornak, John; Kramer, Joel H.; Miller, Bruce L.; Kantarci, Kejal; Knopman, David S.; Graff-Radford, Neill; Petrucelli, Leonard; Rademakers, Rosa; Irwin, David J.; Grossman, Murray; Ramos, Eliana Marisa; Coppola, Giovanni; Mendez, Mario F.; Bordelon, Yvette; Dickerson, Bradford C.; Ghoshal, Nupur; Huey, Edward D.; Mackenzie, Ian R.; Appleby, Brian S.; Domoto-Reilly, Kimiko; Hsiung, Ging-Yuek R.; Toga, Arthur W.; Weintraub, Sandra; Kaufer, Daniel I.; Kerwin, Diana; Litvan, Irene; Onyike, Chiadikaobi U.; Pantelyat, Alexander; Roberson, Erik D.; Tartaglia, Maria C.; Foroud, Tatiana; Chen, Weiping; Czerkowicz, Julie; Graham, Danielle L.; van Swieten, John C.; Borroni, Barbara; Sanchez-Valle, Raquel; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; Galimberti, Daniela; Rowe, James B.; Masellis, Mario; Finger, Elizabeth; Vandenberghe, Rik; de Mendonca, Alexandre; Tagliavini, Fabrizio; Santana, Isabel; Ducharme, Simon; Butler, Chris R.; Gerhard, Alexander; Levin, Johannes; Danek, Adrian; Otto, Markus; Sorbi, Sandro; Cash, David M.; Convery, Rhian S.; Bocchetta, Martina; Foiani, Martha; Greaves, Caroline V.; Peakman, Georgia; Russell, Lucy; Swift, Imogen; Todd, Emily; Rohrer, Jonathan D.; Boeve, Bradley F.; Rosen, Howard J.; Boxer, Adam L. 分享 收藏
Toxin A-Predominant Pathogenic Clostridioides difficile: A Novel Clinical Phenotype Lin, Qianyun; Pollock, Nira R.; Banz, Alice; Lantz, Aude; Xu, Hua; Gu, Limei; Gerding, Dale N.; Garey, Kevin W.; Gonzales-Luna, Anne J.; Zhao, Mingwei; Song, Linan; Duffy, David C.; Kelly, Ciaran P.; Chen, Xinhua 分享 收藏
Glial fibrillary acidic protein elevations relate to neuroimaging abnormalities after mild TBI Gill, Jessica; Latour, Lawrence; Diaz-Arrastia, Ramon; Motamedi, Vida; Turtzo, Christine; Shahim, Pashtun; Mondello, Stefania; DeVoto, Christina; Veras, Eliseo; Hanlon, David; Song, Linan; Jeromin, Andreas 分享 收藏
Increases of Plasma Levels of Glial Fibrillary Acidic Protein, Tau, and Amyloid β up to 90 Days after Traumatic Brain Injury 创伤性脑损伤后90天内血浆胶质纤维酸性蛋白，Tau和淀粉样蛋白 β 水平升高 Bogoslovsky, Tanya; Wilson, David; Chen, Yao; Hanlon, David; Gill, Jessica; Jeromin, Andreas; Song, Linan; Moore, Carol; Gong, Yunhua; Kenney, Kimbra; Diaz-Arrastia, Ramon 分享 收藏
A digital enzyme-linked immunosorbent assay for ultrasensitive measurement of amyloid-β 1-42 peptide in human plasma with utility for studies of Alzheimer's disease therapeutics Song, Linan; Lachno, D. Richard; Hanlon, David; Shepro, Adam; Jeromin, Andreas; Gemani, Dipika; Talbot, Jayne A.; Racke, Margaret M.; Dage, Jeffrey L.; Dean, Robert A. 分享 收藏
Plasma tau in Alzheimer disease Mattsson, Niklas; Zetterberg, Henrik; Janelidze, Shorena; Insel, Philip S.; Andreasson, Ulf; Stomrud, Erik; Palmqvist, Sebastian; Baker, David; Hehir, Cristina A. Tan; Jeromin, Andreas; Hanlon, David; Song, Linan; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael W.; Hansson, Oskar; Blennow, Kaj 分享 收藏
Plasma β-amyloid in Alzheimer's disease and vascular disease Janelidze, Shorena; Stomrud, Erik; Palmqvist, Sebastian; Zetterberg, Henrik; van Westen, Danielle; Jeromin, Andreas; Song, Linan; Hanlon, David; Tan Hehir, Cristina A.; Baker, David; Blennow, Kaj; Hansson, Oskar 分享 收藏
Development and Validation of Digital Enzyme-Linked Immunosorbent Assays for Ultrasensitive Detection and Quantification of Clostridium difficile Toxins in Stool Song, Linan; Zhao, Mingwei; Duffy, David C.; Hansen, Joshua; Shields, Kelsey; Wungjiranirun, Manida; Chen, Xinhua; Xu, Hua; Leffler, Daniel A.; Sambol, Susan P.; Gerding, Dale N.; Kelly, Ciaran P.; Pollock, Nira R. 分享 收藏
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Direct Detection of Bacterial Genomic DNA at Sub-Femtomolar Concentrations Using Single Molecule Arrays Song, Linan; Shan, Dandan; Zhao, Mingwei; Pink, Brian A.; Minnehan, Kaitlin A.; York, Lyndsey; Gardel, Melissa; Sullivan, Sean; Phillips, Aaron F.; Hayman, Ryan B.; Walt, David R.; Duffy, David C. 分享 收藏
Multiplexed single molecule immunoassays Rissin, David M.; Kan, Cheuk W.; Song, Linan; Rivnak, Andrew J.; Fishburn, Matthew W.; Shao, Qichao; Piech, Tomasz; Ferrell, Evan P.; Meyer, Raymond E.; Campbell, Todd G.; Fournier, David R.; Duffy, David C. 分享 收藏
Fifth-Generation Digital Immunoassay for Prostate-Specific Antigen by Single Molecule Array Technology Wilson, David H.; Hanlon, David W.; Provuncher, Gail K.; Chang, Lei; Song, Linan; Patel, Purvish P.; Ferrell, Evan P.; Lepor, Herbert; Partin, Alan W.; Chan, Dan W.; Sokoll, Lori J.; Cheli, Carol D.; Thiel, Robert P.; Fournier, David R.; Duffy, David C. 分享 收藏
Simultaneous Detection of Single Molecules and Singulated Ensembles of Molecules Enables Immunoassays with Broad Dynamic Range Rissin, David M.; Fournier, David R.; Piech, Tomasz; Kan, Cheuk W.; Campbell, Todd G.; Song, Linan; Chang, Lei; Rivnak, Andrew J.; Patel, Purvish P.; Provuncher, Gail K.; Ferrell, Evan P.; Howes, Stuart C.; Pink, Brian A.; Minnehan, Kaitlin A.; Wilson, David H.; Duffy, David C. 分享 收藏
Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations Rissin, David M.; Kan, Cheuk W.; Campbell, Todd G.; Howes, Stuart C.; Fournier, David R.; Song, Linan; Piech, Tomasz; Patel, Purvish P.; Chang, Lei; Rivnak, Andrew J.; Ferrell, Evan P.; Randall, Jeffrey D.; Provuncher, Gail K.; Walt, David R.; Duffy, David C. 分享 收藏
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Phosphopeptide analysis by directly coupling two-dimensional planar electrochromatography/thin-layer chromatography with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Panchagnula, Venkateswarlu; Mikulskis, Alvydas; Song, Linan; Wang, Yang; Wang, Mei; Knubovets, Tanya; Scrivener, Elaine; Golenko, Eva; Krull, Ira S.; Schulz, Michael; Heinz-Emil-Hauck; Patton, Wayne F. 分享 收藏
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