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Alkylation-based optimization of antifungal FPPS inhibitors yields a potent, broad-spectrum lipophilic zoledronate derivative 基于烷基化的抗真菌FPPS抑制剂优化获得了一种强效、广谱的亲脂性唑来磷酸衍生物 Kane, Aidan; Lai, Felcia; Rothwell, Joanna G.; Dinh, Thanh Thi Hue; Campbell, Leona; Cain, Amy K.; Hibbs, David; Hanrahan, Jane; Carter, Dee 分享 收藏
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PK 11195 derivatives: exploring the influence of amide and heterocyclic substitution on A147T TSPO discrimination Sokias, Renee; Zhao, Andrea; Werry, Eryn L.; Montgomery, Andrew P.; Hibbs, David E.; Sullivan, Michael A.; Mckenzie, Andre D. J.; Cumbers, Grace A.; Allen, Beau M.; Danon, Jonathan J.; Kassiou, Michael 分享 收藏
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Structure-Activity Relationships, Deuteration, and Fluorination of Synthetic Cannabinoid Receptor Agonists Related to AKB48, 5F-AKB-48, and AFUBIATA Sparkes, Eric; Maloney, Callan J.; Markham, Jack W.; Dane, Chianna; Boyd, Rochelle; Gilchrist, Jayson; Moir, Michael; Gordon, Rebecca; Luo, Jia Lin; Pike, Edward; Walker, Katelyn A.; Kassiou, Michael; Mcgregor, Iain S.; Kevin, Richard C.; Hibbs, David E.; Jorgensen, William T.; Banister, Samuel D.; Cairns, Elizabeth A.; Ametovski, Adam 分享 收藏
Synthesis and Functional Evaluation of Synthetic Cannabinoid Receptor Agonists Related to ADB-HEXINACA Sparkes, Eric; Timmerman, Axelle; Markham, Jack W.; Boyd, Rochelle; Gordon, Rebecca; Walker, Katelyn A.; Kevin, Richard C.; Hibbs, David E.; Banister, Samuel D.; Cairns, Elizabeth A.; Stove, Christophe; Ametovski, Adam 分享 收藏
Synthesis and functional evaluation of proteinogenic amino acid-derived synthetic cannabinoid receptor agonists related to MPP-5F-PICA, MMB-5F-PICA, and MDMB-5F-PICA Sparkes, Eric; Markham, Jack W.; Boyd, Rochelle; Udoh, Michael; Gordon, Rebecca; Zaman, Humayra; Walker, Katelyn A.; Dane, Chianna; Kevin, Richard C.; Santiago, Marina J.; Hibbs, David E.; Banister, Samuel D.; Ametovski, Adam; Cairns, Elizabeth A. 分享 收藏
Synthesis and Preclinical Evaluation of Fluorinated 5-Azaindoles as CB2 PET Radioligands Kallinen, Annukka; Mardon, Karine; Lane, Samuel; Montgomery, Andrew P.; Bhalla, Rajiv; Stimson, Damion H. R.; Ahamed, Muneer; Cowin, Gary J.; Hibbs, David; Werry, Eryn L.; Fulton, Roger; Connor, Mark; Kassiou, Michael 分享 收藏
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Comprehensive Characterization of a Systematic Library of Alkyl and Alicyclic Synthetic Cannabinoids Related to CUMYL-PICA, CUMYL-BUTICA, CUMYL-CBMICA, and CUMYL-PINACA Janssens, Liesl K.; Ametovski, Adam; Sparkes, Eric; Boyd, Rochelle; Lai, Felcia; Maloney, Callan J.; Rhook, Dane; Gerona, Roy R.; Connolly, Matthew; Liu, Huiling; Hibbs, David E.; Cairns, Elizabeth A.; Banister, Samuel D.; Stove, Christophe P. 分享 收藏
Discovery of 2′,6-Bis(4-hydroxybenzyl)-2-acetylcyclohexanone, a Novel FtsZ Inhibitor Lin, Hsuan-Yu J.; Battaje, Rachana Rao; Tan, Jinlong; Doddareddy, Munikumar; Dhaked, Hemendra Pal Singh; Srivastava, Shalini; Hawkins, Bryson A.; Al-Shdifat, Laith Mohammad Hilal; Hibbs, David E.; Panda, Dulal; Groundwater, Paul W. 分享 收藏
Synthesis and pharmacological evaluation of newly detected synthetic cannabinoid receptor agonists AB-4CN-BUTICA, MMB-4CN-BUTINACA, MDMB-4F-BUTICA, MDMB-4F-BUTINACA and their analogs Sparkes, Eric; Boyd, Rochelle; Chen, Shuli; Markham, Jack W.; Luo, Jia Lin; Foyzun, Tahira; Zaman, Humayra; Fletcher, Charlotte; Ellison, Ross; McGregor, Iain S.; Santiago, Marina J.; Lai, Felcia; Gerona, Roy R.; Connor, Mark; Hibbs, David E.; Cairns, Elizabeth A.; Glass, Michelle; Ametovski, Adam; Banister, Samuel D. 分享 收藏
Putative Synthetic Cannabinoids MEPIRAPIM, 5F-BEPIRAPIM (NNL-2), and Their Analogues Are T-Type Calcium Channel (CaV3) Inhibitors Kevin, Richard C.; Mirlohi, Somayeh; Manning, Jamie J.; Boyd, Rochelle; Cairns, Elizabeth A.; Ametovski, Adam; Lai, Felcia; Luo, Jia Lin; Jorgensen, William; Ellison, Ross; Gerona, Roy R.; Hibbs, David E.; McGregor, Iain S.; Glass, Michelle; Connor, Mark; Bladen, Chris; Zamponi, Gerald W.; Banister, Samuel D. 分享 收藏
Defining Steric Requirements at CB1 and CB2 Cannabinoid Receptors Using Synthetic Cannabinoid Receptor Agonists 5F-AB-PINACA, 5FADB-PINACA, PX-1, PX-2, NNL-1, and Their Analogues Markham, Jack; Sparkes, Eric; Boyd, Rochelle; Chen, Shuli; Manning, Jamie J.; Finlay, David; Lai, Felcia; McGregor, Eila; Maloney, Callan J.; Gerona, Roy R.; Connor, Mark; McGregor, Iain S.; Hibbs, David E.; Glass, Michelle; Kevin, Richard C.; Banister, Samuel D. 分享 收藏
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