未登录 Discovery of an ApoE4-targeted small-molecule SirT1 enhancer for the treatment of Alzheimer's disease 靶向ApoE4的小分子SirT1增强剂的发现及其在阿尔茨海默病治疗中的应用 Campagna, Jesus; Chandra, Sujyoti; Teter, Bruce; Cohn, Whitaker; Pham, Johnny; Kim, Young-Sug; Jagodzinska, Barbara; Vadivel, Kanagasabai; Alam, Parvez; Bilousova, Tina; Young, Malaney; Elias, Chris; Marcucci, Juan; Flacau, Ilinca; Jackman, Ainsley; Padder, Samar; Wi, Dongwook; Zhu, Chunni; Spilman, Patricia; Jung, Michael E.; Bredesen, Dale E.; John, Varghese 分享 收藏
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Combination of CDK4/6 inhibitors with biguanides for treatment of triple negative breast cancer Martinez, Mario Morales; Gonzalez, Eduardo Mauricio; Deng, Gang; Ma, Gaoyuan; Kim, Hyunsoo; Stiles, Linsey; Hamilton, Nalo; Jung, Michael E.; Pietras, Richard J.; Marquez-Garban, Diana C. 分享 收藏
Development of a novel histone deacetylase inhibitor unveils the role of HDAC11 in alleviating depression by inhibition of microglial activation Baek, Soo Yeon; Lee, Jeehee; Kim, Taegwan; Lee, Hyelim; Choi, Hoon-Seong; Park, Hahnbeom; Koh, Minseob; Kim, Eunha; Jung, Michael E.; Iliopoulos, Dimitrios; Lee, Jeong-Yeon; Kim, Jonghoon; Lee, Sanghee 分享 收藏
Targeting metabolic vulnerabilities to reduce triple negative breast cancer health disparities Marquez-Garban, Diana C.; Deng, Gang; Burton, Lorena P.; Ma, Gaoyuan; Muhunthan, Vishaka; Comin-Anduix, Begonya; Llarena, Gabriela; Moatamed, Neda; Murphy, Jennifer; Hamilton, Nalo; Shackelford, Daivd; Jung, Michael E.; Pietras, Richard J. 分享 收藏
Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA Martinez, Orlando E.; Mahoney, Brendan J.; Goring, Andrew K.; Yi, Sung-Wook; Tran, Denise P.; Cascio, Duilio; Phillips, Martin L.; Muthana, Musleh M.; Chen, Xi; Jung, Michael E.; Loo, Joseph A.; Clubb, Robert T. 分享 收藏
Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair Li, Shen; Yokota, Tomohiro; Wang, Ping; Hoeve, Johanna ten; Ma, Feiyang; Le, Thuc M.; Abt, Evan R.; Zhou, Yonggang; Wu, Rimao; Nanthavongdouangsy, Maxine; Rodriguez, Abraham; Wang, Yijie; Lin, Yen-Ju; Muranaka, Hayato; Sharpley, Mark; Braddock, Demetrios T.; MacRae, Vicky E.; Banerjee, Utpal; Chiou, Pei-Yu; Seldin, Marcus; Huang, Dian; Teitell, Michael; Gertsman, Ilya; Jung, Michael; Bensinger, Steven J.; Damoiseaux, Robert; Faull, Kym; Pellegrini, Matteo; Lusis, Aldons J.; Graeber, Thomas G.; Radu, Caius G.; Deb, Arjun 分享 收藏
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Discovery of novel metformin derivatives with potent antitumor activity in combination with immunotherapy for treatment of triple-negative breast cancer Marquez-Garban, Diana C.; Deng, Gang; Comin-Anduix, Begonya; Muhunthan, Vishaka; Ma, Gaoyuan; Murphy, Jennifer; Garcia, Alejandro J.; Yanes, Cristian D.; Burton, Lorena R.; Hamilton, Nalo; Shackelford, David; Jung, Michael E.; Pietras, Richard J. 分享 收藏
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A Cell-based Screen in Actinomyces oris to Identify Sortase Inhibitors Gosschalk, Jason E.; Chang, Chungyu; Sue, Christopher K.; Siegel, Sara D.; Wu, Chenggang; Kattke, Michele D.; Yi, Sung Wook; Damoiseaux, Robert; Jung, Michael E.; Ton-That, Hung; Clubb, Robert T. 分享 收藏
Development of a Potent Brain-Penetrant EGFR Tyrosine Kinase Inhibitor against Malignant Brain Tumors Tsang, Jonathan E.; Urner, Lorenz M.; Kim, Gyudong; Chow, Kingsley; Baufeld, Lynn; Faull, Kym; Cloughesy, Timothy F.; Clark, Peter M.; Jung, Michael E.; Nathanson, David A. 分享 收藏
Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism Abt, Evan R.; Rosser, Ethan W.; Durst, Matthew A.; Lok, Vincent; Poddar, Soumya; Le, Thuc M.; Cho, Arthur; Kim, Woosuk; Wei, Liu; Song, Janet; Capri, Joseph R.; Xu, Shili; Wu, Nanping; Slavik, Roger; Jung, Michael E.; Damoiseaux, Robert; Czernin, Johannes; Donahue, Timothy R.; Lavie, Arnon; Radu, Caius G. 分享 收藏
Development and preclinical pharmacology of a novel dCK inhibitor, DI-87 Poddar, Soumya; Capparelli, Edmund, V; Rosser, Ethan W.; Gipson, Raymond M.; Wei, Liu; Le, Thuc; Jung, Michael E.; Radu, Caius; Nikanjam, Mina 分享 收藏
Isoquinoline thiosemicarbazone displays potent anticancer activity with in vivo efficacy against aggressive leukemias Sun, Daniel L.; Poddar, Soumya; Pan, Roy D.; Rosser, Ethan W.; Abt, Evan R.; Van Valkenburgh, Juno; Le, Thuc M.; Lok, Vincent; Hernandez, Selena P.; Song, Janet; Li, Joanna; Turlik, Aneta; Chen, Xiaohong; Cheng, Chi-An; Chen, Wei; Mona, Christine E.; Stuparu, Andreea D.; Vergnes, Laurent; Reue, Karen; Damoiseaux, Robert; Zink, Jeffrey I.; Czernin, Johannes; Donahue, Timothy R.; Houk, Kendall N.; Jung, Michael E.; Radu, Caius G. 分享 收藏
A Novel Therapeutic Induces DEPTOR Degradation in Multiple Myeloma Cells with Resulting Tumor Cytotoxicity Vega, Mario, I; Shi, Yijiang; Frost, Patrick; Huerta-Yepez, Sara; Antonio-Andres, Gabriela; Hernandez-Pando, Rogelio; Lee, Jihye; Jung, Michael E.; Gera, Joseph F.; Lichtenstein, Alan 分享 收藏
PTPσ inhibitors promote hematopoietic stem cell regeneration Zhang, Yurun; Roos, Martina; Himburg, Heather; Termini, Christina M.; Quarmyne, Mamle; Li, Michelle; Zhao, Liman; Kan, Jenny; Fang, Tiancheng; Yan, Xiao; Pohl, Katherine; Diers, Emelyne; Gim, Hyo Jin; Damoiseaux, Robert; Whitelegge, Julian; McBride, William; Jung, Michael E.; Chute, John P. 分享 收藏
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