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M

Michael K. Pugsley

toxicology and safety pharmacology
H指数:31
被引数:3,787

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Regulatory safety pharmacology & toxicology assessment studies: Measurement of the ECG and hemodynamic parameters in nonrodent species

安全性药理学与毒理学评价研究：非啮齿类物种的心电图和血流动力学参数测量

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
IF1.8
2025-09-010
PRE
Valentina, Jean-Pierre; Bourcierb, Todd; Chib, Xuan; Delaunoisa, Annie; Foleyc, C. Michael; Hendersond, Kim A.; Laineee, Pierre; Leishmanf, Derek J.; Lig, Dingzhou Dean; Pawluka, Emma; Pugsleyh, Michael K.; Rajamanii, Sridharan; Reganj, Christopher P.; Rolfk, Michael G.; Rossmanl, Eric I.; Rossm, Rebecca; Tichenorn, Stephen D.; Vargasd, Hugo M.; Moask, Immaculada C.; Wisialowskig, Todd A.; Wub, Jean
Reevaluating safety pharmacology respiratory studies within the ICH S7A core battery: A multi-company evaluation of preclinical utility and clinical translation

重新评估ICH S7A核心组中的安全性药理学呼吸研究：一项多公司评估，评估其非临床效用和临床转化

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
IF1.8
2025-09-010
PRE
Kremer, John J.; Abernathy, Matt M.; Ackley, David; Clark, Matthew; Dasilva, Jamie K.; Foley, Michael C.; Greiter-Wilke, A.; Henderson-Park, Kim H.; Morimoto, Bruce H.; Paglialunga, Sabina; Pugsley, Michael K.; Regan, Chris P.; Rossman, Eric I.; Segretti, Jason A.; Traebert, Martin; Vargas, Hugo M.; Wisialowski, Todd A.; Friedrichs, Greg S.
QT risk assessment for the development of oligonucleotide therapeutics - An industry survey sponsored by the Safety Pharmacology Society (SPS) ion channel working group and oligonucleotide safety working group

寡核苷酸治疗药物开发的QT风险评估——由安全药理学学会（SPS）离子通道工作组与寡核苷酸安全性工作组赞助的行业调查

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
IF1.8
2025-09-010
PRE
Chaudhary, Khuram; Lagrutta, Armando; Melliti, Karim; Traebert, Martin; Brimecombe, Jessica; Pugsley, Michael; Qu, Yusheng; Hebeisen, Simon; Martin, Ruth; Stoelzle-Feix, Sonja; Foy, Jeff; Harper, Tod; Leishman, Derek; Valentin, Jean-Pierre; Vargas, Hugo
Characterization of vasoactive agents in a canine safety pharmacology PKPD model: A HESI initiative

血管活性剂在犬安全性药理学PKPD模型中的表征：一项HESI倡议

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
IF1.8
2025-09-010
PRE
Koshmana, Yevgeniya E.; Foleya, C. Michael; Piersonb, Jennifer; Bhattc, Siddhartha; Wisialowskic, Todd; Vargasd, Hugo A.; Hoffmanne, Peter; Nortonf, Kevin; Rossmang, Eric I.; Osinskih, Mark A.; Ashcroft-Hawleyi, Kelly; Pugsleyj, Michael K.
Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&As (vol 123, 107270, 2023)

非啮齿类动物非临床在体心血管遥测研究最佳实践考量：提供高质量QTc数据以支持ICH E14/S7B答疑（卷123，107270，2023）

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
IF1.8
2025-09-010
OAAI
Rossman, Eric I.; Wisialowski, Todd A.; Vargas, Hugo M.; Valentin, Jean-Pierre; Rolf, Michael G.; Roche, Brian M.; Riley, Steve; Pugsley, Michael K.; Nicholsi, Jill; Li, Dingzhou; Leishman, Derek J.; Kleiman, Robert B.; Greiter-Wilke, Andrea; Gintant, Gary A.; Engwall, Michael J.; Delaunois, Annie; Authier, Simon
Reevaluating safety pharmacology respiratory studies within the ICH S7A core battery: A multi-company evaluation of preclinical utility and clinical translation

重新评估ICH S7A核心电池内的安全药理学呼吸研究: 临床前效用和临床翻译的多公司评估

REGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
2024-11-010
PRE
Friedrichs, G. S.; Abernathy, M. M.; Ackley, D.; Clark, M.; DaSilva, J. K.; Foley, C. M.; Greiter-Wilke, A.; Henderson, K. A.; Kremer, J. J.; Morimoto, B. H.; Paglialunga, S.; Pugsley, M. K.; Regan, C. P.; Rossman, E. I.; Segretti, J. A.; Traebert, M.; Vargas, H. M.; Wisialowski, T. A.
Opportunities for use of one species for longer-term toxicology testing during drug development: A cross-industry evaluation
REGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
2020-06-0127
OAAI
Prior, Helen; Baldrick, Paul; Beken, Sonja; Booler, Helen; Bower, Nancy; Brooker, Paul; Brown, Paul; Burlinson, Brian; Burns-Naas, Leigh Ann; Casey, Warren; Chapman, Melissa; Clarke, David; de Haan, Lolke; Doehr, Olaf; Downes, Noel; Flaherty, Meghan; Gellatly, Nichola; Moesgaard, Sophia Gry; Harris, Jennifer; Holbrook, Mark; Hui, Julia; Jones, David; Jones, Keith; Kedar, Hilla; Mahl, Andreas; Manninen, Alli; McGuire, Aidan; Mortimer-Cassen, Elisabeth; Peraza, Marjorie; Pugsley, Michael K.; Richard, Jacques; Roberts, Ruth; Roosen, Wendy; Rothfuss, Andreas; Schoenmakers, Ankie; Sewell, Fiona; Weaver, Richard; Weir, Lucinda; Wolfreys, Alison; Kimber, Ian

研究方向

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S
Simon Authier
H 指数:0论文数:3被引数:0
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Hugo M. Vargas
H 指数:38论文数:220被引数:4,365
E
Eric I. Rossman
H 指数:16论文数:74被引数:895
E
Eric Hayes
H 指数:21论文数:84被引数:1,194
A
Alan L. Goldin
H 指数:56论文数:110被引数:1.4万
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Todd Wisialowski
H 指数:20论文数:78被引数:1,277
M
Michael Walker
H 指数:41论文数:291被引数:7,553
C
C. Michael Foley
H 指数:18论文数:84被引数:1,011
J
Jean‐Pierre Valentin
H 指数:45论文数:364被引数:6,189