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H

Hugo M. Vargas

Amgen Research
H指数:38
被引数:4,365

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Regulatory safety pharmacology & toxicology assessment studies: Measurement of the ECG and hemodynamic parameters in nonrodent species

安全性药理学与毒理学评价研究：非啮齿类物种的心电图和血流动力学参数测量

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
IF1.8
2025-09-010
PRE
Valentina, Jean-Pierre; Bourcierb, Todd; Chib, Xuan; Delaunoisa, Annie; Foleyc, C. Michael; Hendersond, Kim A.; Laineee, Pierre; Leishmanf, Derek J.; Lig, Dingzhou Dean; Pawluka, Emma; Pugsleyh, Michael K.; Rajamanii, Sridharan; Reganj, Christopher P.; Rolfk, Michael G.; Rossmanl, Eric I.; Rossm, Rebecca; Tichenorn, Stephen D.; Vargasd, Hugo M.; Moask, Immaculada C.; Wisialowskig, Todd A.; Wub, Jean
Reevaluating safety pharmacology respiratory studies within the ICH S7A core battery: A multi-company evaluation of preclinical utility and clinical translation

重新评估ICH S7A核心组中的安全性药理学呼吸研究：一项多公司评估，评估其非临床效用和临床转化

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
IF1.8
2025-09-010
PRE
Kremer, John J.; Abernathy, Matt M.; Ackley, David; Clark, Matthew; Dasilva, Jamie K.; Foley, Michael C.; Greiter-Wilke, A.; Henderson-Park, Kim H.; Morimoto, Bruce H.; Paglialunga, Sabina; Pugsley, Michael K.; Regan, Chris P.; Rossman, Eric I.; Segretti, Jason A.; Traebert, Martin; Vargas, Hugo M.; Wisialowski, Todd A.; Friedrichs, Greg S.
QT risk assessment for the development of oligonucleotide therapeutics - An industry survey sponsored by the Safety Pharmacology Society (SPS) ion channel working group and oligonucleotide safety working group

寡核苷酸治疗药物开发的QT风险评估——由安全药理学学会（SPS）离子通道工作组与寡核苷酸安全性工作组赞助的行业调查

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
IF1.8
2025-09-010
PRE
Chaudhary, Khuram; Lagrutta, Armando; Melliti, Karim; Traebert, Martin; Brimecombe, Jessica; Pugsley, Michael; Qu, Yusheng; Hebeisen, Simon; Martin, Ruth; Stoelzle-Feix, Sonja; Foy, Jeff; Harper, Tod; Leishman, Derek; Valentin, Jean-Pierre; Vargas, Hugo
Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&As (vol 123, 107270, 2023)

非啮齿类动物非临床在体心血管遥测研究最佳实践考量：提供高质量QTc数据以支持ICH E14/S7B答疑（卷123，107270，2023）

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
IF1.8
2025-09-010
OAAI
Rossman, Eric I.; Wisialowski, Todd A.; Vargas, Hugo M.; Valentin, Jean-Pierre; Rolf, Michael G.; Roche, Brian M.; Riley, Steve; Pugsley, Michael K.; Nicholsi, Jill; Li, Dingzhou; Leishman, Derek J.; Kleiman, Robert B.; Greiter-Wilke, Andrea; Gintant, Gary A.; Engwall, Michael J.; Delaunois, Annie; Authier, Simon
Reevaluating safety pharmacology respiratory studies within the ICH S7A core battery: A multi-company evaluation of preclinical utility and clinical translation

重新评估ICH S7A核心电池内的安全药理学呼吸研究: 临床前效用和临床翻译的多公司评估

REGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
2024-11-010
PRE
Friedrichs, G. S.; Abernathy, M. M.; Ackley, D.; Clark, M.; DaSilva, J. K.; Foley, C. M.; Greiter-Wilke, A.; Henderson, K. A.; Kremer, J. J.; Morimoto, B. H.; Paglialunga, S.; Pugsley, M. K.; Regan, C. P.; Rossman, E. I.; Segretti, J. A.; Traebert, M.; Vargas, H. M.; Wisialowski, T. A.
Time for a Fully Integrated Nonclinical-Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective
CLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
2020-09-2468
OAAI
Vargas, Hugo M.; Rolf, Michael G.; Wisialowski, Todd A.; Achanzar, William; Bahinski, Anthony; Bass, Alan; Benson, Charles T.; Chaudhary, Khuram W.; Couvreur, Nicolas; Dota, Corina; Engwall, Michael J.; Michael Foley, C.; Gallacher, David; Greiter-Wilke, Andrea; Guillon, Jean-Michel; Guth, Brian; Himmel, Herbert M.; Hegele-Hartung, Christa; Ito, Maki; Jenkinson, Stephen; Chiba, Katsuyoshi; Lagrutta, Armando; Levesque, Paul; Martel, Eric; Okai, Yoshiko; Peri, Ravikumar; Pointon, Amy; Qu, Yusheng; Teisman, Ard; Traebert, Martin; Yoshinaga, Takashi; Gintant, Gary A.; Leishman, Derek J.; Valentin, Jean-Pierre
Cardiovascular response to small-molecule APJ activation
JCI INSIGHT
IF6.1
2020-04-2330
OA
Ason, Brandon; Chen, Yinhong; Guo, Qi; Hoagland, Kimberly M.; Chui, Ray W.; Fielden, Mark; Sutherland, Weston; Chen, Rhonda; Zhang, Ying; Mihardja, Shirley; Ma, Xiaochuan; Li, Xun; Sun, Yaping; Liu, Dongming; Nguyen, Khanh; Wang, Jinghong; Li, Ning; Rajamani, Sridharan; Qu, Yusheng; Gao, BaoXi; Boden, Andrea; Chintalgattu, Vishnu; Turk, Jim R.; Chan, Joyce; Hu, Liaoyuan A.; Dransfield, Paul; Houze, Jonathan; Wong, Jingman; Ma, Ji; Pattaropong, Vatee; Veniant, Murielle M.; Vargas, Hugo M.; Swaminath, Gayathri; Khakoo, Aarif Y.

研究方向

暂未获取到该数据
Y
Yusheng Qu
H 指数:24论文数:74被引数:3,215
M
Michael K. Pugsley
H 指数:31论文数:204被引数:3,787
J
Jean‐Pierre Valentin
H 指数:45论文数:364被引数:6,189
B
BaoXi Gao
H 指数:9论文数:32被引数:318
D
Derek J. Leishman
H 指数:24论文数:172被引数:1,986
M
Michael J. Engwall
H 指数:20论文数:62被引数:974
R
Ray W. Chui
H 指数:18论文数:61被引数:1,167
T
Todd Wisialowski
H 指数:20论文数:78被引数:1,277
M
Martin Traebert
H 指数:32论文数:124被引数:3,748
A
Andrea Greiter‐Wilke
H 指数:16论文数:63被引数:1,072