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Aleksander S. Popel

johns hopkins university

74H指数
565论文数
2.0W被引数
收录论文 144
发表时间
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Structured Schemas for Provenance-Rich, LLM-Assisted QSP Model Calibration溯源丰富的LLM辅助QSP模型校准的结构化模式
errCPT-Pharmacometrics & Systems Pharmacology
IF3
err2026-09-15
err0
errOAAI
errJoel Eliason; Aleksander S. Popel
err分享
err收藏
Experimental and computational studies of IL-6 signaling in endothelial cells under hypoxia serum starvation conditions缺氧血清饥饿条件下内皮细胞中IL-6信号通路的实验与计算研究
errCytokine
IF3.7
err2025-09-13
err0
PREAI
errMin Song; Youli Wang; Brian H. Annex; Aleksander S. Popel
err分享
err收藏
A mechanistic computational model of HGF-VEGF-mediated endothelial cell proliferation and vascular permeabilityHGF-VEGF介导的内皮细胞增殖和血管通透性的机制性计算模型
erriScience
IF4.1
err2025-07-24
err0
errOAAI
errRebeca Hannah de Melo Oliveira; Akash Patil; Brian H. Annex; Arvind P. Pathak; Aleksander S. Popel
err分享
err收藏
Bispecific receptor decoy proteins block ocular neovascularization via simultaneous blockade of vascular endothelial growth factor A and C双特异性受体诱饵蛋白通过同时阻断血管内皮生长因子A和C来抑制眼部新生血管形成
errMolecular Therapy
IF12
err2025-03-25
err0
PREAI
errPaul R. Sargunas; Emily Ariail; Raquel Lima e Silva; Akash Patil; Mingliang Zhang; Jikui Shen; Beatriz Silva Lopes; Yuseong Oh; Amelia C. McCue; Ranjani Ramasubramanian; A. Carson Stephenson; Aleksander S. Popel; Peter A. Campochiaro; Jamie B. Spangler
err分享
err收藏
Bi-level graph learning unveils prognosis-relevant tumor microenvironment patterns in breast multiplexed digital pathology双层次图学习揭示乳腺多重数字病理中与预后相关的肿瘤微环境模式
errPATTERNS
IF7.4
err2025-02-01
err0
errOAAI
errWang, Zhenzhen; Santa-Maria, Cesar A.; Popel, Aleksander S.; Sulam, Jeremias
err分享
err收藏
Spatial Architecture of Single-Cell and Vasculature in Tumor Microenvironment Predicts Clinical Outcomes in Triple-Negative Breast Cancer
errMODERN PATHOLOGY
IF5.5
err2025-02-01
err0
PREAI
errMi, Haoyang; Varadhan, Ravi; Cimino-Mathews, Ashley M.; Emens, Leisha A.; Santa-Maria, Cesar A.; Popel, Aleksander S.
err分享
err收藏
Quantitative Spatial Profiling of Immune Populations in Pancreatic Ductal Adenocarcinoma Reveals Tumor Microenvironment Heterogeneity and Prognostic Biomarkers (vol 82, pg 4359, 2022)
errCANCER RESEARCH
IF16.6
err2024-11-04
err0
errOAAI
errMi, Haoyang; Sivagnanam, Shamilene; Betts, Courtney B.; Liudahl, Shannon M.; Jaffee, Elizabeth M.; Coussens, Lisa M.; Popel, Aleksander S.
err分享
err收藏
Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade虚拟患者分析确定了提高PD-1阻断预测性生物标志物性能的策略
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-10-28
err0
errOAAI
errArulraj, Theinmozhi; Wang, Hanwen; Deshpande, Atul; Varadhan, Ravi; Emens, Leisha A.; Jaffee, Elizabeth M.; Fertig, Elana J.; Santa-Maria, Cesar A.; Popel, Aleksander S.
err分享
err收藏
Identifying biomarkers for treatment of uveal melanoma by T cell engager using a QSP model使用QSP模型鉴定T细胞接合器治疗葡萄膜黑色素瘤的生物标志物
errNPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
err2024-09-30
err2
errOAAI
errAnbari, Samira; Wang, Hanwen; Arulraj, Theinmozhi; Nickaeen, Masoud; Pilvankar, Minu; Wang, Jun; Hansel, Steven; Popel, Aleksander S.
err分享
err收藏
Computational methods and biomarker discovery strategies for spatial proteomics: a review in immuno-oncology空间蛋白质组学的计算方法和生物标志物发现策略: 免疫肿瘤学综述
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2024-08-23
err1
errOAAI
errMi, Haoyang; Sivagnanam, Shamilene; Ho, Won Jin; Zhang, Shuming; Bergman, Daniel; Deshpande, Atul; Baras, Alexander S.; Jaffee, Elizabeth M.; Coussens, Lisa M.; Fertig, Elana J.; Popel, Aleksander S.
err分享
err收藏
From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling从虚拟患者到免疫肿瘤学中的数字双胞胎: 从机械定量系统药理学建模中学到的经验教训
errNPJ DIGITAL MEDICINE
IF15.1
err2024-07-16
err3
errOAAI
errWang, Hanwen; Arulraj, Theinmozhi; Ippolito, Alberto; Popel, Aleksander S.
err分享
err收藏
Integration of Clinical Trial Spatial Multiomics Analysis and Virtual Clinical Trials Enables Immunotherapy Response Prediction and Biomarker Discovery
errCANCER RESEARCH
IF16.6
err2024-06-11
err5
PREAI
errZhang, Shuming; Deshpande, Atul; Verma, Babita K.; Wang, Hanwen; Mi, Haoyang; Yuan, Long; Ho, Won Jin; Jaffee, Elizabeth M.; Zhu, Qingfeng; Anders, Robert A.; Yarchoan, Mark; Kagohara, Luciane T.; Fertig, Elana J.; Popel, Aleksander S.
err分享
err收藏
Quantitative systems pharmacology modeling of macrophage-targeted therapy combined with PD-L1 inhibition in advanced NSCLC晚期NSCLC巨噬细胞靶向治疗联合PD-L1抑制的定量系统药理学模型
errCTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
err2024-05-30
err1
errOAAI
errWang, Hanwen; Arulraj, Theinmozhi; Anbari, Samira; Popel, Aleksander S.
err分享
err收藏
Chemokine-derived oncolytic peptide induces immunogenic cancer cell death and significantly suppresses tumor growth
errCELL DEATH DISCOVERY
IF7
err2024-04-02
err1
errOAAI
errFurukawa, Natsuki; Yang, Wendy; Chao, Alex R.; Patil, Akash; Mirando, Adam C.; Pandey, Niranjan B.; Popel, Aleksander S.
err分享
err收藏
Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology利用多组学数据来增强免疫肿瘤学中的定量系统药理学
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2024-03-31
err4
errOAAI
errArulraj, Theinmozhi; Wang, Hanwen; Ippolito, Alberto; Zhang, Shuming; Fertig, Elana J.; Popel, Aleksander S.
err分享
err收藏
Integrating spatial multi-omics data with spatial quantitative pharmacology (spQSP) model to simulate human neoadjuvant immunotherapy clinical trial of hepatocellular carcinoma
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errZhang, Shuming; Deshpande, Atul; Verma, Babita K.; Wang, Hanwen; Mi, Haoyang; Yuan, Long; Ho, Won Jin; Jaffee, Elizabeth M.; Zhu, Qingfeng; Anders, Robert A.; Yarchoan, Mark; Kagohara, Luciane T.; Fertig, Elana J.; Popel, Aleksander S.
err分享
err收藏
Endothelial cells signaling and patterning under hypoxia: a mechanistic integrative computational model including the Notch-Dll4 pathway
errFRONTIERS IN PHYSIOLOGY
IF3.4
err2024-02-22
err3
errOAAI
errOliveira, Rebeca Hannah de Melo; Annex, Brian H.; Popel, Aleksander S.
err分享
err收藏
Signaling-biophysical modeling unravels mechanistic control of red blood cell phagocytosis by macrophages in sickle cell disease信号-生物物理模型解开了镰状细胞病中巨噬细胞对红细胞吞噬作用的机制控制
errPNAS NEXUS
IF3.8
err2024-01-20
err5
errOAAI
errZhang, Yu; Qiang, Yuhao; Li, He; Li, Guansheng; Lu, Lu; Dao, Ming; Karniadakis, George E.; Popel, Aleksander S.; Zhao, Chen
err分享
err收藏
Eliciting the antitumor immune response with a conditionally activated PD-L1 targeting antibody analyzed with a quantitative systems pharmacology model用定量系统药理学模型分析的条件激活的PD-L1靶向抗体引起抗肿瘤免疫反应
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2023-12-07
err5
errOAAI
errIppolito, Alberto; Wang, Hanwen; Zhang, Yu; Vakil, Vahideh; Bazzazi, Hojjat; Popel, Aleksander S.
err分享
err收藏
Experiment-based computational model predicts that IL-6 classic and trans-signaling exhibit similar potency in inducing downstream signaling in endothelial cells基于实验的计算模型预测，IL-6经典和反式信号在诱导内皮细胞下游信号方面表现出相似的效力
errNPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
err2023-09-21
err1
errOAAI
errSong, Min; Wang, Youli; Annex, Brian H.; Popel, Aleksander S.
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
A
Alexander S. Szalay
H 指数: 132 · 论文数: 939
G
George Em Karniadakis
H 指数: 130 · 论文数: 1.2K
P
Peter A. Campochiaro
H 指数: 112 · 论文数: 541
E
Elizabeth M. Jaffee
H 指数: 112 · 论文数: 1.4K
L
Lisa M. Coussens
H 指数: 100 · 论文数: 628
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