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J

Jaroslav Pejchal

military faculty of medicine

24H指数
157论文数
1.7K被引数
收录论文 45
发表时间
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Next-generation broad-spectrum reactivators for effective countermeasure against organophosphorus poisoning下一代广谱重活化剂，用于有效对抗有机磷中毒的对策
errArchives of Toxicology
IF6.9
err2026-03-16
err0
errOAAI
errJana Zdarova Karasova; Martina Hrabinova; Alzbeta Dlabkova; Vendula Hepnarova; Natalie Zivna; Monika Schmidt; Valeria Sheshko; Carilyn Torruellas; Jakub Opravil; Lukas Prchal; Natalie Vanova; Jakub Fibigar; Zbynek Vecera; Tomas Kucera; Jaroslav Chladek; Gabriele Horn; Franz Worek; Jan Marek; Jaroslav Pejchal; Daniel Jun; Ondrej Soukup; Jan Korabecny; Lukas Gorecki
err分享
err收藏
A case report of fatal chlormequat poisoning: Identification of potential additional mechanism of toxicity一例致命矮壮素中毒的病例报告：潜在额外毒性机制的鉴定
errScience Progress
IF2.9
err2025-11-04
err0
errOAAI
errMichal Čečrle; Martin Mžik; Alžběta Dlabková; Lubica Múčková; Martina Hrabinová; Lenka Fikejzlova; Jakub Opravil; Nela Váňová; Petr Hejna; Štěpánka Pohlová Kučerová; David Astapenko; Martin Jakl; Jaroslav Chladek; Jana Žďárová Karaová; Jaroslav Pejchal
err分享
err收藏
Reactivation screening of A-234-inhibited human recombinant acetylcholinesterase in vitroA-234抑制的人重组乙酰胆碱酯酶的体外重激活筛选
errChemico-Biological Interactions
IF5.4
err2025-11-04
err0
PREAI
errJakub Opravil; Jaroslav Pejchal; Martina Hrabinova; Lubica Muckova; Lukas Prchal; Jan Korabecny; Tomas Rozsypal; Lukas Gorecki; Jakub Fibigar; Ondrej Soukup; Kamil Musilek; Daniel Jun
err分享
err收藏
Evaluation of novel surfactants for the decontamination of chemical warfare agents新型表面活性剂在化学战剂去污中的应用评估
errTOXICOLOGY MECHANISMS AND METHODS
IF2.7
err2025-09-01
err0
PREAI
errMatula, Marek; Pejchal, Jaroslav; Marek, Jan; Ernestova, Viktoria; Zivna, Natalie; Markova, Aneta Voparilova; Rehulkova, Helena; Dlabkova, Alzbeta
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ADMET parameters of tacrine and its metabolites confirm unsuitability of Sus scrofa f. domestica model to study tacrine-associated hepatotoxicity他克林及其代谢物的ADMET参数证实，猪属家猪亚种模型不适合用于研究他克林相关的肝毒性。
errCHEMICO-BIOLOGICAL INTERACTIONS
IF5.4
err2025-05-27
err0
PREAI
errNovak, M.; Bures, J.; Radochova, V.; Pejchal, J.; Prchal, L.; Soukup, O.
err分享
err收藏
Dimethyl fumarate attenuates bile acid retention and liver fibrosis in a mouse model of cholestasis二甲基富马酸减弱胆汁酸滞留和肝纤维化，在胆汁淤积小鼠模型中
errAMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
IF3.3
err2025-05-01
err0
PREAI
errLastuvkova, H; Dohnalkova, E; Manna, DF; Cermanova, J; Mokry, J; Pejchal, J; Hirsova, P; Nachtigal, P; Pavkova, I; Bajnokova, M; Smutna, L; Stefela, A; Kamaraj, R; Jandova, L; Uher, M; Pavek, P; Micuda, S; Hroch, M
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Dizocilpine derivatives as neuroprotective NMDA receptor antagonists without psychomimetic side effects
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-12-01
err0
errOAAI
errKonecny, Jan; Misiachna, Anna; Chvojkova, Marketa; Kleteckova, Lenka; Kolcheva, Marharyta; Novak, Martin; Prchal, Lukas; Ladislav, Marek; Hemelikova, Katarina; Netolicky, Jakub; Hrabinova, Martina; Kobrlova, Tereza; Karasova, Jana Zdarova; Pejchal, Jaroslav; Fibigar, Jakub; Vecera, Zbynek; Kucera, Tomas; Jendelova, Pavla; Zahumenska, Petra; Langore, Emily; Doderovic, Jovana; Pang, Yuan-Ping; Vales, Karel; Korabecny, Jan; Soukup, Ondrej; Horak, Martin
err分享
err收藏
The Effect of Tacrine on Functional Response of the Lower Oesophageal Sphincter Assessed by Endoscopic Luminal Impedance Planimetry in Experimental Pigs
errPHARMACEUTICALS
IF4.8
err2024-11-25
err0
errOAAI
errBures, Jan; Novak, Martin; Radochova, Vera; Kohoutova, Darina; Prchal, Lukas; Martinek, Jan; Mares, Jan; Cerny, Jaroslav; Suchanek, Stepan; Pejchal, Jaroslav; Voxova, Barbora; Urbanek, Petr; Zavoral, Miroslav; Soukup, Ondrej
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Multifunctional, Fluorene-Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-11-22
err0
errOAAI
errPanek, Dawid; Pasieka, Anna; Jonczyk, Jakub; Gawlinska, Milena; Zareba, Paula; Siwek, Agata; Wolak, Malgorzata; Mordyl, Barbara; Gluch-Lutwin, Monika; Latacz, Gniewomir; Brazzolotto, Xavier; Chantegreil, Fabien; Nachon, Florian; Zdarova Karasova, Jana; Pejchal, Jaroslav; Mzik, Martin; Sestak, Vit; Prchal, Lukas; Odvarkova, Jitka; Soukup, Ondrej; Korabecny, Jan; Sorf, Ales; Hamsikova, Marie; Zemanova, Lucie; Muckova, Lubica; Vanova, Nela; Dryja, Pola; Salat, Kinga; Hoefner, Georg; Wanner, Klaus; Wieckowska, Anna; Malawska, Barbara
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err收藏
In Vivo Assessment on Freeze-Cast Calcium Phosphate-Based Scaffolds with a Selective Cell/Tissue Ingrowth
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2024-10-21
err0
errOAAI
errPejchalova, Lucie; Pejchal, Jaroslav; Rolecek, Jakub; Vojnikova, Michaela; Chlup, Zdenek; Marak, Vojtech; Gonzalez-Sanchez, Manuela; Cizkova, Jana; Salamon, David
err分享
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Potent and reversible open-channel blocker of NMDA receptor derived from dizocilpine with enhanced membrane-to-channel inhibition
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2024-09-01
err1
errOAAI
errMisiachna, Anna; Konecny, Jan; Kolcheva, Marharyta; Ladislav, Marek; Prchal, Lukas; Netolicky, Jakub; Kortus, Stepan; Zahumenska, Petra; Langore, Emily; Novak, Martin; Hemelikova, Katarina; Hermanova, Zuzana; Hrochova, Michaela; Pelikanova, Anezka; Odvarkova, Jitka; Pejchal, Jaroslav; Kassa, Jiri; Karasova, Jana Zdarova; Korabecny, Jan; Soukup, Ondrej; Horak, Martin
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Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents溴化肟亲核试剂有效地重新激活被神经毒剂抑制的胆碱酯酶
errARCHIVES OF TOXICOLOGY
IF6.9
err2024-05-24
err2
PREAI
errPrchalova, Eliska; Andrys, Rudolf; Pejchal, Jaroslav; Kohoutova, Zuzana; Knittelova, Karolina; Hofmanova, Tereza; Skarka, Adam; Dlabkova, Alzbeta; Psotka, Miroslav; Prchal, Lukas; Musilek, Kamil; Karasova, Jana Zdarova; Malinak, David
err分享
err收藏
A-series agent A-234: initial in vitro and in vivo characterization
errARCHIVES OF TOXICOLOGY
IF6.9
err2024-03-06
err7
errOAAI
errHrabinova, Martina; Pejchal, Jaroslav; Hepnarova, Vendula; Muckova, Lubica; Junova, Lucie; Opravil, Jakub; Zdarova Karasova, Jana; Rozsypal, Tomas; Dlabkova, Alzbeta; Rehulkova, Helena; Kucera, Tomas; Vecera, Zbynek; Caisberger, Filip; Schmidt, Monika; Soukup, Ondrej; Jun, Daniel
err分享
err收藏
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition苯氧他克林衍生物: 低毒性神经保护剂，对ifenprodil结合位点和胆碱酯酶抑制具有亲和力
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-02-01
err8
errOAAI
errMisiachna, Anna; Svobodova, Barbora; Netolicky, Jakub; Chvojkova, Marketa; Kleteckova, Lenka; Prchal, Lukas; Novak, Martin; Hrabinova, Martina; Kucera, Tomas; Muckova, Lubica; Moravcova, Zuzana; Karasova, Jana Zdarova; Pejchal, Jaroslav; Blazek, Filip; Malinak, David; Hakenova, Kristina; Krausova, Barbora Hrcka; Kolcheva, Marharyta; Ladislav, Marek; Korabecny, Jan; Pahnke, Jens; Vales, Karel; Horak, Martin; Soukup, Ondrej
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err收藏
Second-generation piperazine derivatives as promising radiation countermeasures
errRSC MEDICINAL CHEMISTRY
IF3.6
err2024-01-01
err0
errOAAI
errChmil, Vojtech; Zivna, Natalie; Milanova, Marcela; Filipova, Alzbeta; Pejchal, Jaroslav; Prchal, Lukas; Muthna, Darina; Rehacek, Vit; Rezacova, Martina; Marek, Jan; Tichy, Ales; Havelek, Radim
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The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease (vol 159, 114223, 2023)
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2023-09-01
err0
errOAAI
errValis, Martin; Dlabkova, Alzbeta; Hort, Jakub; Angelucci, Francesco; Pejchal, Jaroslav; Kuca, Kamil; Pavelek, Zbysek; Karasova, Jana Zdarova; Novotny, Michal
err分享
err收藏
A-agents, misleadingly known as Novichoks: a narrative review
errARCHIVES OF TOXICOLOGY
IF6.9
err2023-08-24
err12
errOAAI
errOpravil, Jakub; Pejchal, Jaroslav; Finger, Vladimir; Korabecny, Jan; Rozsypal, Tomas; Hrabinova, Martina; Muckova, Lubica; Hepnarova, Vendula; Konecny, Jan; Soukup, Ondrej; Jun, Daniel
err分享
err收藏
The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2023-03-01
err1
errOAAI
errValis, Martin; Dlabkova, Alzbeta; Hort, Jakub; Angelucci, Francesco; Pejchal, Jaroslav; Kuca, Kamil; Pavelek, Zbysek; Karasova, Jana Zdarova; Novotny, Michal
err分享
err收藏
Neurotoxicity evoked by organophosphates and available countermeasures
errARCHIVES OF TOXICOLOGY
IF6.9
err2022-11-06
err26
PREAI
errPulkrabkova, Lenka; Svobodova, Barbora; Konecny, Jan; Kobrlova, Tereza; Muckova, Lubica; Janousek, Jiri; Pejchal, Jaroslav; Korabecny, Jan; Soukup, Ondrej
err分享
err收藏
UHPLC-HRMS study of pharmacokinetics of a novel hybrid cholinesterase inhibitor K1234: A comparison between in silico, in vitro and in vivo data
errJOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
IF3.1
err2022-09-01
err0
PREAI
errMzik, M.; Sestak, V; Mezeiova, E.; Korabecny, J.; Hroch, M.; Pejchal, J.; Karasova-Zdarova, J.
err分享
err收藏

研究方向

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