Malcolm Rowland - Publications, H-index & Citations

Malcolm Rowland

University of Michigan

75H指数

425论文数

2.1W被引数

收录论文 53

发表时间

Target Reserve and Turnover Parameters Determine Rightward Shift of Enalaprilat Potency From its Binding Affinity to the Angiotensin Converting Enzyme

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2024-01-01

PREAI

Nguyen, Van Anh; Zhang, Li; Kagan, Leonid; Rowland, Malcolm; Mager, Donald E.

Hepatic clearance models and IVIVE predictions

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2022-03-01

PREAI

Rowland, Malcolm; Pang, K. Sandy

Phase 0/microdosing approaches: time for mainstream application in drug development?第0阶段/微剂量方法: 药物开发主流应用的时间？

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2020-09-08

OAAI

Burt, Tal; Young, Graeme; Lee, Wooin; Kusuhara, Hiroyuki; Langer, Oliver; Rowland, Malcolm; Sugiyama, Yuichi

Hepatic clearance concepts and misconceptions: Why the well-stirred model is still used even though it is not physiologic reality?

BIOCHEMICAL PHARMACOLOGY

IF5.6

2019-11-01

PREAI

Pang, K. Sandy; Han, Yi Rang; Noh, Keumhan; Lee, Ping I.; Rowland, Malcolm

Importance of target-mediated drug disposition for small molecules

DRUG DISCOVERY TODAY

IF7.5

2018-12-01

PREAI

Smith, Dennis A.; van Waterschoot, Robert A. B.; Parrott, Neil J.; Olivares-Morales, Andres; Lave, Thierry; Rowland, Malcolm

Past, Present, and Future of Bioequivalence: Improving Assessment and Extrapolation of Therapeutic Equivalence for Oral Drug Products

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2018-10-01

PREAI

Cristofoletti, Rodrigo; Rowland, Malcolm; Lesko, Lawrence J.; Blume, Henning; Rostami-Hodjegan, Amin; Dressman, Jennifer B.

Impact of target interactions on small-molecule drug disposition: an overlooked area

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2018-02-23

PREAI

van Waterschoot, Robert A. B.; Parrott, Neil J.; Olivares-Morales, Andres; Lave, Thierry; Rowland, Malcolm; Smith, Dennis A.

Physiologically Based Pharmacokinetic Model Qualification and Reporting Procedures for Regulatory Submissions: A Consortium Perspective

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2018-02-02

273

OAAI

Shebley, Mohamad; Sandhu, Punam; Riedmaier, Arian Emami; Jamei, Masoud; Narayanan, Rangaraj; Patel, Aarti; Peters, Sheila Annie; Reddy, Venkatesh Pilla; Zheng, Ming; de Zwart, Loeckie; Beneton, Maud; Bouzom, Francois; Chen, Jun; Chen, Yuan; Cleary, Yumi; Collins, Christiane; Dickinson, Gemma L.; Djebli, Nassim; Einolf, Heidi J.; Gardner, Iain; Huth, Felix; Kazmi, Faraz; Khalil, Feras; Lin, Jing; Odinecs, Aleksandrs; Patel, Chirag; Rong, Haojing; Schuck, Edgar; Sharma, Pradeep; Wu, Shu-Pei; Xu, Yang; Yamazaki, Shinji; Yoshida, Kenta; Rowland, Malcolm

Whole body physiologically based modelling of β-blockers in the rat: events in tissues and plasma following an i.v. bolus dose

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2017-12-01

OAAI

Cheung, S. Y. A.; Rodgers, T.; Aarons, L.; Gueorguieva, I.; Dickinson, G. L.; Murby, S.; Brown, C.; Collins, B.; Rowland, M.

Commentary on The Universally Unrecognized Assumption in Predicting Drug Clearance and Organ Extraction Ratio

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2017-11-14

PREAI

Rowland, Malcolm; Pang, K. Sandy

Intra-Target Microdosing - A Novel Drug Development Approach: Proof of Concept, Safety, and Feasibility Study in Humans

CTS-CLINICAL AND TRANSLATIONAL SCIENCE

IF2.8

2017-07-08

OAAI

Burt, T.; MacLeod, D.; Lee, K.; Santoro, A.; DeMasi, D. K.; Hawk, T.; Feinglos, M.; Rowland, M.; Noveck, R. J.

Intra-Target Microdosing (ITM): A Novel Drug Development Approach Aimed at Enabling Safer and Earlier Translation of Biological Insights Into Human Testing

CTS-CLINICAL AND TRANSLATIONAL SCIENCE

IF2.8

2017-04-18

OAAI

Burt, T.; Noveck, R. J.; MacLeod, D. B.; Layton, A. T.; Rowland, M.; Lappin, G.

Microdosing and Other Phase 0 Clinical Trials: Facilitating Translation in Drug Development

CTS-CLINICAL AND TRANSLATIONAL SCIENCE

IF2.8

2016-03-30

OAAI

Burt, T.; Yoshida, K.; Lappin, G.; Vuong, L.; John, C.; de Wildt, S. N.; Sugiyama, Y.; Rowland, M.

Are Physiologically Based Pharmacokinetic Models Reporting the Right Cmax? Central Venous Versus Peripheral Sampling Site

AAPS JOURNAL

IF3.7

2015-06-23

OAAI

Musther, Helen; Gill, Katherine L.; Chetty, Manoranjenni; Rostami-Hodjegan, Amin; Rowland, Malcolm; Jamei, Masoud

Disposition Kinetics of Diclofenac in the Dual Perfused Rat Liver

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2013-09-01

OAAI

Sahin, Selma; Rowland, Malcolm

Tissue lipids and drug distribution: Dog versus rat

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2012-12-01

PREAI

Rodgers, Trudy; Jones, Hannah M.; Rowland, Malcolm

Factors influencing non-approval of new drugs in Europe

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2012-11-30

PREAI

Putzeist, Michelle; Mantel-Teeuwisse, Aukje K.; Aronsson, Bo; Rowland, Malcolm; Gispen-de Wied, Christine C.; Vamvakas, Spiros; Hoes, Arno W.; Leufkens, Hubert G. M.; Eichler, Hans-Georg

Cyclosporine Inhibition of Hepatic and Intestinal CYP3A4, Uptake and Efflux Transporters: Application of PBPK Modeling in the Assessment of Drug-Drug Interaction Potential

PHARMACEUTICAL RESEARCH

IF4.3

2012-11-22

137

PREAI

Gertz, Michael; Cartwright, Catherine M.; Hobbs, Michael J.; Kenworthy, Kathryn E.; Rowland, Malcolm; Houston, J. Brian; Galetin, Aleksandra

Impact of the pharmaceutical sciences on health care: A reflection over the past 50 years

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2012-11-01

PREAI

Rowland, Malcolm; Noe, Christian R.; Smith, Dennis A.; Tucker, G. T.; Crommelin, Daan J. A.; Peck, Carl C.; Rocci, Mario L., Jr.; Besancon, Luc; Shah, Vinod P.

Dedication to Professor Leslie Z. Benet: 50 Years of Scientific Excellence and Still Going Strong!

PHARMACEUTICAL RESEARCH

IF4.3

2012-07-20

OAAI

Smith, David E.; Rowland, Malcolm; Giacomini, Kathleen M.; Amidon, Gordon L.

研究方向