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T

Travis K. Hughes

Harvard University
H指数:25
被引数:7,921

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Single-cell and spatial profiling highlights TB-induced myofibroblasts as drivers of lung pathology

单细胞和空间分析揭示结核分枝杆菌诱导的肌成纤维细胞是肺病理学的驱动因素

Journal of Experimental Medicine
IF10.6
2026-01-053
PRE
Mbano, Ian M.; Liu, Nuo; Wadsworth II, Marc H.; Chambers, Mark J.; Mpotje, Thabo; Asowata, Osaretin E.; Nyquist, Sarah K.; Nargan, Kievershen; Ramsuran, Duran; Karim, Farina; Hughes, Travis K.; Bromley, Joshua D.; Krause, Robert; Naidoo, Threnesan; Tezera, Liku B.; Reichmann, Michaela T.; Ganchua, Sharie Keanne; Kloverpris, Henrik N.; Dullabh, Kaylesh J.; Madansein, Rajhmun; Triana, Sergio; Steyn, Adrie J. C.; Berger, Bonnie; Marakalala, Mohlopheni J.; Fortune, Sarah M.; Flynn, JoAnne L.; Elkington, Paul T.; Shalek, Alex K.; Leslie, Alasdair
Single-cell profiling reveals a role for tuberculosis-induced myofibroblasts in the immunopathology of infected lungs
JOURNAL OF IMMUNOLOGY
IF3.4
2025-11-010
PRE
Liu, Nuo; Mbano, Ian Maheti; Wardsworth, Marc; Chambers, Mark; Mpotje, Thabo; Asowata, Osaretin; Nyquist, Sarah; Nargan, Kievershen; Ramsuran, Duran; Karim, Farina; Hughes, Travis; Bromley, Joshua; Krause, Robert; Tezera, Liku; Reichmann, Michaela; Keanne, Sharie; Ganchua, C.; Kloverpris, Henrik; Dullabh, Kaylesh; Madansein, Rajhmun; Triana, Sergio; Steyn, Adrie; Berger, Bonnie; Marakalala, Mohlopheni; Fortune, Sarah; Flynn, Joanne L.; Elkington, Paul T.; Shalek, Alex K.; Leslie, Alasdair
High-dose intravenous BCG vaccination induces enhanced immune signaling in the airways

高剂量静脉BCG疫苗接种诱导气道中增强的免疫信号传导

SCIENCE ADVANCES
IF12.5
2025-01-031
PRE
Peters, Joshua M.; Irvine, Edward B.; Makatsa, Mohau S.; Rosenberg, Jacob M.; Wadsworth II, Marc H.; Hughes, Travis K.; Sutton, Matthew S.; Nyquist, Sarah K.; Bromley, Joshua D.; Mondal, Rajib; Seder, Robert A.; Darrah, Patricia A.; Seshadri, Chetan; Flynn, JoAnne L.; Shalek, Alex K.; Fortune, Sarah M.
Single-Cell RNA Sequencing Reveals That Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress

单细胞RNA测序揭示了人主动脉内皮细胞对抗增殖疗法的适应性是由流动诱导的剪切应力调节的

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
IF7.4
2023-12-011
OAAI
Salazar-Martin, Antonio G.; Kalluri, Aditya S.; Villanueva, Martin A.; Hughes, Travis K.; Wadsworth, Marc H.; Dao, Tyler T.; Balcells, Mercedes; Nezami, Farhad R.; Shalek, Alex K.; Edelman, Elazer R.
CD8+ lymphocytes are critical for early control of tuberculosis in macaques

CD8淋巴细胞对猕猴结核病的早期控制至关重要

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2023-10-1613
OAAI
Winchell, Caylin G.; Nyquist, Sarah K.; Chao, Michael C.; Maiello, Pauline; Myers, Amy J.; Hopkins, Forrest; Chase, Michael; Gideon, Hannah P.; Patel, Kush V.; Bromley, Joshua D.; Simonson, Andrew W.; Floyd-O'Sullivan, Roisin; Wadsworth, Marc; Rosenberg, Jacob M.; Uddin, Rockib; Hughes, Travis; Kelly, Ryan J.; Griffo, Josephine; Tomko, Jaime; Klein, Edwin; Berger, Bonnie; Scanga, Charles A.; Mattila, Joshua; Fortune, Sarah M.; Shalek, Alex K.; Lin, Philana Ling; Flynn, JoAnne L.
Uncommitted cells and phenotypic plasticity elucidate the complexity of the epithelial-mesenchymal molecular gradient of pleural mesothelioma
CANCER RESEARCH
IF16.6
2023-04-040
PRE
Severson, David T.; Freyaldenhoven, Samuel; Wadowski, Benjamin; Hughes, Travis; Hung, Yin P.; Jensen, Roderick V.; Richards, William G.; Gustafson, Corinne E.; Vermilya, Kimberly; Innocenti, Simona; Barlow, Julianne S.; Cougar, Matthew B.; Anderson, Jamie; Wang, Vivian; Dao, Mary N.; Shalek, Alex K.; De Rienzo, Assunta; Bueno, Raphael
Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation

环境性肠病的单细胞分析揭示了上皮重塑和免疫激活的特征

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-08-319
OA
Kummerlowe, Conner; Mwakamui, Simutanyi; Hughes, Travis K.; Mulugeta, Nolawit; Mudenda, Victor; Besa, Ellen; Zyambo, Kanekwa; Shay, Jessica E. S.; Fleming, Ira; Vukovic, Marko; Doran, Ben A.; Aicher, Toby P.; Wadsworth, Marc H., II; Bramante, Juliet Tongue; Uchida, Amiko M.; Fardoos, Rabiah; Asowata, Osaretin E.; Herbert, Nicholas; Yilmaz, Omer H.; Kloverpris, Henrik N.; Garber, John J.; Ordovas-Montanes, Jose; Gartner, Zev J.; Wallach, Thomas; Shalek, Alex K.; Kelly, Paul
Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation
FRONTIERS IN IMMUNOLOGY
IF5.9
2022-07-2823
OAAI
Bassler, Kevin; Fujii, Wataru; Kapellos, Theodore S.; Dudkin, Erika; Reusch, Nico; Horne, Ari; Reiz, Benedikt; Luecken, Malte D.; Osei-Sarpong, Collins; Warnat-Herresthal, Stefanie; Bonaguro, Lorenzo; Schulte-Schrepping, Jonas; Wagner, Allon; Guenther, Patrick; Pizarro, Carmen; Schreiber, Tina; Knoll, Rainer; Holsten, Lisa; Kroeger, Charlotte; De Domenico, Elena; Becker, Matthias; Haendler, Kristian; Wohnhaas, Christian T.; Baumgartner, Florian; Koehler, Meike; Theis, Heidi; Kraut, Michael; Wadsworth, Marc H.; Hughes, Travis K.; Ferreira, Humberto J.; Hinkley, Emily; Kaltheuner, Ines H.; Geyer, Matthias; Thiele, Christoph; Shalek, Alex K.; Feisst, Andreas; Thomas, Daniel; Dickten, Henning; Beyer, Marc; Baum, Patrick; Yosef, Nir; Aschenbrenner, Anna C.; Ulas, Thomas; Hasenauer, Jan; Theis, Fabian J.; Skowasch, Dirk; Schultze, Joachim L.
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

猕猴肺部肉芽肿的多模式分析揭示了结核病控制的细胞相关性

IMMUNITY
IF26.3
2022-05-0196
OAAI
Gideon, Hannah P.; Hughes, Travis K.; Tzouanas, Constantine N.; Wadsworth, Marc H., II; Tu, Ang Andy; Gierahn, Todd M.; Peters, Joshua M.; Hopkins, Forrest F.; Wei, Jun-Rong; Kummerlowe, Conner; Nargan, Kievershen; Phuah, Jia Yao; Borish, H. Jacob; Maiello, Pauline; White, Alexander G.; Winchell, Caylin G.; Nyquist, Sarah K.; Ganchua, Sharie Keanne C.; Myers, Amy; V. Patel, Kush; Ameel, Cassaundra L.; Cochran, Catherine T.; Ibrahim, Samira; Tomko, Jaime A.; Frye, Lonnie James; Rosenberg, Jacob M.; Shih, Angela; Chao, Michael; Klein, Edwin; Scanga, Charles A.; Ordovas-Montanes, Jose; Berger, Bonnie; Mattila, Joshua T.; Madansein, Rajhmun; Love, J. Christopher; Lin, Philana Ling; Leslie, Alasdair; Behar, Samuel M.; Bryson, Bryan; Flynn, JoAnne L.; Fortune, Sarah M.; Shalek, Alex K.
Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells
CELL REPORTS
IF6.9
2022-04-016
OAAI
Morris, Vivian; Wang, Dahai; Li, Zhiheng; Marion, William; Hughes, Travis; Sousa, Patricia; Harada, Taku; Sui, Shannan Ho; Naumenko, Sergey; Kalfon, Jeremie; Sensharma, Prerana; Falchetti, Marcelo; da Silva, Renan Vinicius; Candelli, Tito; Schneider, Pauline; Margaritis, Thanasis; Holstege, Frank C. P.; Pikman, Yana; Harris, Marian; Stam, Ronald W.; Orkin, Stuart H.; Koehler, Angela N.; Shalek, Alex K.; North, Trista E.; Pimkin, Maxim; Daley, George Q.; da Rocha, Edroaldo Lummertz; Rowe, R. Grant
The cellular architecture of the antimicrobial response network in human leprosy granulomas
NATURE IMMUNOLOGY
IF27.6
2021-06-2453
OAAI
Ma, Feiyang; Hughes, Travis K.; Teles, Rosane M. B.; Andrade, Priscila R.; de Andrade Silva, Bruno J.; Plazyo, Olesya; Tsoi, Lam C.; Do, Tran; Wadsworth, Marc H., II; Oulee, Aislyn; Ochoa, Maria Teresa; Sarno, Euzenir N.; Luisa Iruela-Arispe, M.; Klechevsky, Eynav; Bryson, Bryan; Shalek, Alex K.; Bloom, Barry R.; Gudjonsson, Johann E.; Pellegrini, Matteo; Modlin, Robert L.
Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation

在2型炎症期间，人气道肥大细胞增殖并获得不同的炎症驱动表型

SCIENCE IMMUNOLOGY
IF16.3
2021-02-12110
OA
Dwyer, Daniel F.; Ordovas-Montanes, Jose; Allon, Samuel J.; Buchheit, Kathleen M.; Vukovic, Marko; Derakhshan, Tahereh; Feng, Chunli; Lai, Juying; Hughes, Travis K.; Nyquist, Sarah K.; Giannetti, Matthew P.; Berger, Bonnie; Bhattacharyya, Neil; Roditi, Rachel E.; Katz, Howard R.; Nawijn, Martijn C.; Berg, Marijn; van den Berge, Maarten; Laidlaw, Tanya M.; Shalek, Alex K.; Barrett, Nora A.; Boyce, Joshua A.
Systematic comparison of single-cell and single-nucleus RNA-sequencing methods (vol 17, pg 891, 2020)
NATURE BIOTECHNOLOGY
IF41.7
2020-04-275
OAAI
Ding, Jiarui; Adiconis, Xian; Simmons, Sean K.; Kowalczyk, Monika S.; Hession, Cynthia C.; Marjanovic, Nemanja D.; Hughes, Travis K.; Wadsworth, Marc H.; Burks, Tyler; Nguyen, Lan T.; Kwon, John Y. H.; Barak, Boaz; Ge, William; Kedaigle, Amanda J.; Carroll, Shaina; Li, Shuqiang; Hacohen, Nir; Rozenblatt-Rosen, Orit; Shalek, Alex K.; Villani, Alexandra-Chloe; Regev, Aviv; Levin, Joshua Z.

研究方向

暂未获取到该数据
A
Alex K. Shalek
H 指数:81论文数:494被引数:4.8万
M
Marc H. Wadsworth
H 指数:29论文数:86被引数:1.5万
S
Sarah K. Nyquist
H 指数:18论文数:62被引数:8,330
S
Sarah M. Fortune
H 指数:62论文数:247被引数:2.0万
B
Bonnie Berger
H 指数:85论文数:518被引数:3.4万
A
Amr H. Sawalha
H 指数:66论文数:298被引数:1.2万
B
Bryan D. Bryson
H 指数:27论文数:134被引数:5,734
J
Jacob M. Rosenberg
H 指数:17论文数:39被引数:1,358
J
Joshua D. Bromley
H 指数:8论文数:35被引数:612
J
José Ordovás-Montañés
H 指数:38论文数:126被引数:1.3万