未登录 The protein deacetylase SIRT2 exerts metabolic control over adaptive J3 cell proliferation 蛋白质去乙酰化酶SIRT2对适应性J3细胞增殖发挥代谢调控作用 Wortham, Matthew; Ramms, Bastian; Zeng, Chun; Benthuysen, Jacqueline R.; Sai, Somesh; Pollow, Dennis P.; Liu, Fenfen; Schlichting, Michael; Harrington, Austin R.; Liu, Bradley; Prakash, Thazha P.; Pirie, Elaine C.; Zhu, Han; Baghdasarian, Siyouneh; Lee, Sean T.; Ruthig, Victor A.; Wells, Kristen L.; Auwerx, Johan; Shirihai, Orian S.; Sander, Maike 分享 收藏
Murine nuclear tyrosyl-tRNA synthetase deficiency leads to fat storage deficiency and hearing loss Jones, Julia A.; Zhou, Jiadong; Dong, Jianjie; Huitron-Resendiz, Salvador; Boussaty, Ely; Chavez, Eduardo; Wei, Na; Dumitru, Calin Dan; Morodomi, Yosuke; Kanaji, Taisuke; Ryan, Allen F.; Friedman, Rick; Zhou, Tong; Kanaji, Sachiko; Wortham, Matthew; Schenk, Simon; Roberts, Amanda J.; Yang, Xiang-Lei 分享 收藏
A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction Bender, R. Hugh F.; ODonnell, Benjamen T.; Shergill, Bhupinder; Pham, Brittany Q.; Tahmouresie, Sima; Sanchez, Celeste N.; Juat, Damie J.; Hatch, Michaela M. S.; Shirure, Venktesh S.; Wortham, Matthew; Nguyen-Ngoc, Kim-Vy; Jun, Yesl; Gaetani, Roberto; Christman, Karen L.; Teyton, Luc; George, Steven C.; Sander, Maike; Hughes, Christopher C. W. 分享 收藏
Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding 骨形态发生蛋白 (BMP)-2诱导的 β 细胞功能障碍与组蛋白修饰和NeuroD1染色质结合减少有关 Urizar, Adriana Ibarra; Prause, Michala; Ingerslev, Lars Roed; Wortham, Matthew; Sui, Yinghui; Sander, Maike; Williams, Kristine; Barres, Romain; Larsen, Martin R.; Christensen, Gitte Lund; Billestrup, Nils 分享 收藏
Nutrient regulation of the islet epigenome controls adaptive insulin secretion Wortham, Matthew; Liu, Fenfen; Harrington, Austin R.; Fleischman, Johanna Y.; Wallace, Martina; Mulas, Francesca; Mallick, Medhavi; Vinckier, Nicholas K.; Cross, Benjamin R.; Chiou, Joshua; Patel, Nisha A.; Sui, Yinghui; McGrail, Carolyn; Jun, Yesl; Wang, Gaowei; Jhala, Ulupi S.; Schuele, Roland; Shirihai, Orian S.; Huising, Mark O.; Gaulton, Kyle J.; Metallo, Christian M.; Sander, Maike 分享 收藏
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Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance Shum, Michael; Segawa, Mayuko; Gharakhanian, Raffi; Vinuela, Ana; Wortham, Matthew; Baghdasarian, Siyouneh; Wolf, Dane M.; Sereda, Samuel B.; Nocito, Laura; Stiles, Linsey; Zhou, Zhiqiang; Gutierrez, Vincent; Sander, Maike; Shirihai, Orian S.; Liesa, Marc 分享 收藏
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LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development Vinckier, Nicholas K.; Pate, Nisha A.; Geusz, Ryan J.; Wang, Allen; Wang, Jinzhao; Matta, Ileana; Harrington, Austin R.; Wortham, Matthew; Wetton, Nichole; Wang, Jianxun; Jhala, Ulupi S.; Rosenfeld, Michael G.; Benner, Christopher W.; Shih, Hung-Ping; Sander, Maike 分享 收藏
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Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function Wortham, Matthew; Benthuysen, Jacqueline R.; Wallace, Martina; Savas, Jeffrey N.; Mulas, Francesca; Divakaruni, Ajit S.; Liu, Fenfen; Albert, Verena; Taylor, Brandon L.; Sui, Yinghui; Saez, Enrique; Murphy, Anne N.; Yates, John R., III; Metallo, Christian M.; Sander, Maike 分享 收藏
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Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways Guo, Changcun; Chang, Chun-Chi; Wortham, Matthew; Chen, Lee H.; Kernagis, Dawn N.; Qin, Xiaoxia; Cho, Young-Wook; Chi, Jen-Tsan; Grant, Gerald A.; McLendon, Roger E.; Yan, Hai; Ge, Kai; Papadopoulos, Nickolas; Bigner, Darell D.; He, Yiping 分享 收藏
Extensive Evolutionary Changes in Regulatory Element Activity during Human Origins Are Associated with Altered Gene Expression and Positive Selection Shibata, Yoichiro; Sheffield, Nathan C.; Fedrigo, Olivier; Babbitt, Courtney C.; Wortham, Matthew; Tewari, Alok K.; London, Darin; Song, Lingyun; Lee, Bum-Kyu; Iyer, Vishwanath R.; Parker, Stephen C. J.; Margulies, Elliott H.; Wray, Gregory A.; Furey, Terrence S.; Crawford, Gregory E. 分享 收藏
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OTX2 copy number gain is a driver event in Shh-independent medulloblastomas Wortham, Matthew; Adamson, David C.; Shi, Qun; Northcott, Paul A.; Di, Chunhui; Duncan, Christopher G.; Li, Jianjun; McLendon, Roger E.; Bigner, Darell D.; Taylor, Michael D.; Yan, Hai 分享 收藏
OTX2 Is Critical for the Maintenance and Progression of Shh-Independent Medulloblastomas Adamson, David C.; Shi, Qun; Wortham, Matthew; Northcott, Paul A.; Di, Chunhui; Duncan, Christopher G.; Li, Jianjun; McLendon, Roger E.; Bigner, Darell D.; Taylor, Michael D.; Yan, Hai 分享 收藏
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