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Christiane Guguen‐Guillouzo

centre national de la recherche scientifique (cnrs)
H指数:58
被引数:1.3万
浏览量:0

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Extended lifespan and improved genome stability in HepaRG-derived cell lines through reprogramming by high-density stress
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-08-281
OAAI
Brun, Charlotte; Allain, Coralie; Ferron, Pierre-Jean; Younoussa, Haifaou; Colicchio, Bruno; Jeandidier, Eric; M'Kacher, Radhia; Guguen-Guillouzo, Christiane; Bertile, Fabrice
In-Depth Proteome Analysis Highlights HepaRG Cells as a Versatile Cell System Surrogate for Primary Human Hepatocytes
CELLS
IF5.2
2019-02-2159
OAAI
Tascher, Georg; Burban, Audrey; Camus, Sandrine; Plumel, Marine; Chanon, Stephanie; Le Guevel, Remy; Shevchenko, Valery; Van Dorsselaer, Alain; Lefai, Etienne; Guguen-Guillouzo, Christiane; Bertile, Fabrice
Predictive Value of Cellular Accumulation of Hydrophobic Bile Acids As a Marker of Cholestatic Drug Potential
TOXICOLOGICAL SCIENCES
IF4.1
2019-01-109
OAAI
Burban, Audrey; Sharanek, Ahmad; Humbert, Lydie; Eguether, Thibaut; Guguen-Guillouzo, Christiane; Rainteau, Dominique; Guillouzo, Andre
Expansion of human primary hepatocytes in vitro through their amplification as liver progenitors in a 3D organoid system
SCIENTIFIC REPORTS
IF3.9
2018-05-2960
OAAI
Garnier, Delphine; Li, Ruoya; Delbos, Frederic; Fourrier, Angelique; Collet, Camille; Guguen-Guillouzo, Christiane; Chesne, Christophe; Tuan Huy Nguyen
Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes
FREE RADICAL BIOLOGY AND MEDICINE
IF8.2
2018-02-0149
PREAI
Burban, Audrey; Sharanek, Ahmad; Guguen-Guillouzo, Christiane; Guillouzo, Andre
Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways
SCIENTIFIC REPORTS
IF3.9
2017-05-1225
OAAI
Burban, Audrey; Sharanek, Ahmad; Hue, Romain; Gay, Marion; Routier, Sylvain; Guillouzo, Andre; Guguen-Guillouzo, Christiane
Mechanistic Insights in Cytotoxic and Cholestatic Potential of the Endothelial Receptor Antagonists Using HepaRG Cells
TOXICOLOGICAL SCIENCES
IF4.1
2017-03-2415
OAAI
Burbank, Matthew Gibson; Sharanek, Ahmad; Burban, Audrey; Mialanne, Herve; Aerts, Helene; Guguen-Guillouzo, Christiane; Weaver, Richard John; Guillouzo, Andre
Novel optimization of valmerins (tetrahydropyrido[1,2-a] isoindolones) as potent dual CDK5/GSK3 inhibitors
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2016-06-0122
PREAI
Ouach, Aziz; Boulahjar, Rajaa; Vala, Christine; Bourg, Stephane; Bonnet, Pascal; Guguen-Guillouzo, Christiane; Ravache, Myriam; Le Guevel, Remy; Lozach, Olivier; Lazar, Said; Troin, Yves; Meijer, Laurent; Ruchaud, Sandrine; Akssira, Mohamed; Guillaumet, Gerald; Routier, Sylvain
Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs
SCIENTIFIC REPORTS
IF3.9
2016-05-1268
OAAI
Sharanek, Ahmad; Burban, Audrey; Burbank, Matthew; Le Guevel, Remy; Li, Ruoya; Guillouzo, Andre; Guguen-Guillouzo, Christiane
Functional polymer-dependent 3D culture accelerates the differentiation of HepaRG cells into mature hepatocytes
HEPATOLOGY RESEARCH
IF3.4
2016-02-0748
OAAI
Higuchi, Yichiro; Kawai, Kenji; Kanaki, Tatsuro; Yamazaki, Hiroshi; Chesne, Christophe; Guguen-Guillouzo, Christiane; Suemizu, Hiroshi
Hepatic differentiation of human pluripotent stem cells on human liver progenitor HepaRG-derived acellular matrix
EXPERIMENTAL CELL RESEARCH
IF3.5
2016-02-0125
PREAI
Kanninen, Liisa K.; Porola, Pauliina; Niklander, Johanna; Malinen, Melina M.; Corlu, Anne; Guguen-Guillouzo, Christiane; Urtti, Arto; Yliperttula, Marjo L.; Lou, Yan-Ru
Two persistent organic pollutants which act through different xenosensors (alpha-endosulfan and 2,3,7,8 tetrachlorodibenzo-p-dioxin) interact in a mixture and downregulate multiple genes involved in human hepatocyte lipid and glucose metabolism
BIOCHIMIE
IF3
2015-09-0132
OAAI
Ambolet-Camoit, Ariane; Ottolenghi, Chris; Leblanc, Alix; Kim, Min Ji; Letourneur, Franck; Jacques, Sebastien; Cagnard, Nicolas; Guguen-Guillouzo, Christiane; Barouki, Robert; Aggerbeck, Martine
Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2015-08-0129
OAAI
Boulahjar, Rajaa; Ouach, Aziz; Bourg, Stephane; Bonnet, Pascal; Lozach, Olivier; Meijer, Laurent; Guguen-Guillouzo, Christiane; Le Guevel, Remy; Lazar, Said; Akssira, Mohamed; Troin, Yves; Guillaumet, Gerald; Routier, Sylvain
Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes
TOXICOLOGICAL SCIENCES
IF4.1
2015-02-1769
OAAI
Bachour-El Azzi, Pamela; Sharanek, Ahmad; Burban, Audrey; Li, Ruoya; Le Guevel, Remy; Abdel-Razzak, Ziad; Stieger, Bruno; Guguen-Guillouzo, Christiane; Guillouzo, Andre
Liver X receptor α (LXRα/NR1H3) regulates differentiation of hepatocyte-like cells via reciprocal regulation of HNF4α
JOURNAL OF HEPATOLOGY
IF33
2014-12-0115
OAAI
Chen, Kai-Ting; Pernelle, Kelig; Tsai, Yuan-Hau; Wu, Yu-Hsuan; Hsieh, Jui-Yu; Liao, Ko-Hsun; Guguen-Guillouzo, Christiane; Wang, Hsei-Wei
Different Dose-Dependent Mechanisms Are Involved in Early Cyclosporine A-Induced Cholestatic Effects in HepaRG Cells
TOXICOLOGICAL SCIENCES
IF4.1
2014-09-1254
OAAI
Sharanek, Ahmad; Bachour-El Azzi, Pamela; Al-Attrache, Houssein; Savary, Camille C.; Humbert, Lydie; Rainteau, Dominique; Guguen-Guillouzo, Christiane; Guillouzo, Andre
Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells
HEPATOLOGY
IF15.8
2013-04-01116
OA
Antherieu, Sebastien; Bachour-El Azzi, Pamela; Dumont, Julie; Abdel-Razzak, Ziad; Guguen-Guillouzo, Christiane; Fromenty, Bernard; Robin, Marie-Anne; Guillouzo, Andre
Nanofibrillar cellulose hydrogel promotes three-dimensional liver cell culture
JOURNAL OF CONTROLLED RELEASE
IF11.5
2012-12-01361
OAAI
Bhattacharya, Madhushree; Malinen, Melina M.; Lauren, Patrick; Lou, Yan-Ru; Kuisma, Saara W.; Kanninen, Liisa; Lille, Martina; Corlu, Anne; GuGuen-Guillouzo, Christiane; Ikkala, Olli; Laukkanen, Antti; Urtti, Arto; Yliperttula, Marjo
Novel Tetrahydropyrido[1,2-a]isoindolone Derivatives (Valmerins): Potent Cyclin-Dependent Kinase/Glycogen Synthase Kinase 3 Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2012-11-0155
PREAI
Boulahjar, Rajaa; Ouach, Aziz; Matteo, Chiurato; Bourg, Stephane; Ravache, Myriam; le Guevel, Remy; Marionneau, Severine; Oullier, Thibauld; Lozach, Olivier; Meijer, Laurent; Guguen-Guillouzo, Christiane; Lazar, Said; Akssira, Mohamed; Troin, Yves; Guillaumet, Gerald; Routier, Sylvain
Three-Dimensional HepaRG Model As An Attractive Tool for Toxicity Testing
TOXICOLOGICAL SCIENCES
IF4.1
2012-07-2789
OA
Leite, Sofia B.; Wilk-Zasadna, Iwona; Zaldivar, Jose M.; Airola, Elodie; Reis-Fernandes, Marcos A.; Mennecozzi, Milena; Guguen-Guillouzo, Christiane; Chesne, Christopher; Guillou, Claude; Alves, Paula M.; Coecke, Sandra

研究方向

暂未获取到该数据
A
Anne Corlu
H 指数:39论文数:181被引数:5,420
P
Pascal Loyer
H 指数:38论文数:136被引数:4,743
D
Denise Glaise
H 指数:35论文数:114被引数:6,846
A
André Guillouzo
H 指数:64论文数:300被引数:1.2万
P
Philippe Gripon
H 指数:29论文数:89被引数:5,323
D
David Gilot
H 指数:30论文数:103被引数:3,565
R
Rémy Le Guével
H 指数:24论文数:136被引数:2,266
A
Audrey Burban
H 指数:15论文数:47被引数:832
A
Ahmad Sharanek
H 指数:15论文数:53被引数:843
G
Georges Baffet
H 指数:37论文数:128被引数:4,369