Judith M. LaLonde - Publications, H-index & Citations

Judith M. LaLonde

Bryn Mawr College

28H指数

58论文数

4.3K被引数

收录论文 20

发表时间

Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition 小分子CD4-Mimics: 基于结构的HIV-1进入抑制优化

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2016-01-19

OAAI

Melillo, Bruno; Liang, Shuaiyi; Park, Jongwoo; Schoen, Arne; Courter, Joel R.; LaLonde, Judith M.; Wendler, Daniel J.; Princiotto, Amy M.; Seaman, Michael S.; Freire, Ernesto; Sodroski, Joseph; Madani, Navid; Hendrickson, Wayne A.; Smith, Amos B., III

O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2016-01-01

OAAI

Malachowski, William P.; Winters, Maria; DuHadaway, James B.; Lewis-Ballester, Ariel; Badir, Shorouk; Wai, Jenny; Rahman, Maisha; Sheikh, Eesha; LaLonde, Judith M.; Yeh, Syun-Ru; Prendergast, George C.; Muller, Alexander J.

CD4-Mimetic Small Molecules Sensitize Human Immunodeficiency Virus to Vaccine-Elicited Antibodies

JOURNAL OF VIROLOGY

IF3.8

2014-06-15

OAAI

Madani, Navid; Princiotto, Amy M.; Schoen, Arne; LaLonde, Judith; Feng, Yu; Freire, Ernesto; Park, Jongwoo; Courter, Joel R.; Jones, David M.; Robinson, James; Liao, Hua-Xin; Moody, M. Anthony; Permar, Sallie; Haynes, Barton; Smith, Amos B., III; Wyatt, Richard; Sodroski, Joseph

Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2014-02-06

OAAI

Courter, Joel R.; Madani, Navid; Sodroski, Joseph; Schoen, Arne; Freire, Ernesto; Kwong, Peter D.; Hendrickson, Wayne A.; Chaiken, Irwin M.; LaLonde, Judith M.; Smith, Amos B., III

Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-ray and Thermodynamic Characterization 利用x射线和热力学表征的基于结构的HIV-1进入抑制剂的设计和合成

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2013-02-11

OAAI

LaLonde, Judith M.; Le-Khac, Matthew; Jones, David M.; Courter, Joel R.; Park, Jongwoo; Schoen, Arne; Princiotto, Amy M.; Wu, Xueling; Mascola, John R.; Freire, Ernesto; Sodroski, Joseph; Madani, Navid; Hendrickson, Wayne A.; Smith, Amos B., III

HIV-1 ENV gp120 structural determinants for peptide triazole dual receptor site antagonism

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2012-10-26

OAAI

Tuzer, Ferit; Madani, Navid; Kamanna, Kantharaju; Zentner, Isaac; LaLonde, Judith; Holmes, Andrew; Upton, Elizabeth; Rajagopal, Srivats; McFadden, Karyn; Contarino, Mark; Sodroski, Joseph; Chaiken, Irwin

Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2012-04-23

104

OAAI

LaLonde, Judith M.; Kwon, Young Do; Jones, David M.; Sun, Alexander W.; Courter, Joel R.; Soeta, Takahiro; Kobayashi, Toyoharu; Princiotto, Amy M.; Wu, Xueling; Schoen, Arne; Freire, Ernesto; Kwong, Peter D.; Mascola, John R.; Sodroski, Joseph; Madani, Navid; Smith, Amos B., III

A Molecular Dynamics Simulation of Peptide-Triazole HIV Entry Inhibitor Binding to gp120 Hydrophobic Core

BIOPHYSICAL JOURNAL

IF3.1

2012-01-01

OAAI

Emileh, Ali; Tuzer, Ferit; Moreira, Diogo R.; LaLonde, Judith M.; Bewley, Carole A.; Chaiken, Irwin M.; Abrams, Cameron F.

Structure-Based Identification and Neutralization Mechanism of Tyrosine Sulfate Mimetics That Inhibit HIV-1 Entry

ACS CHEMICAL BIOLOGY

IF3.8

2011-08-05

OAAI

Acharya, Priyamvada; Dogo-Isonagie, Cajetan; LaLonde, Judith M.; Lam, Son N.; Leslie, George J.; Louder, Mark K.; Frye, Leah L.; Debnath, Asim K.; Greenwood, Jeremy R.; Luongo, Timothy S.; Martin, Loic; Watts, K. Shawn; Hoxie, James A.; Mascola, John R.; Bewley, Carole A.; Kwong, Peter D.

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2011-02-02

OAAI

Schoen, Arne; Madani, Navid; Smith, Amos B.; Lalonde, Judith M.; Freire, Ernesto

Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening 基于虚拟筛选的CD4-gp120结合小分子抑制剂的设计、合成及生物学评价

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2011-01-01

OAAI

LaLonde, Judith M.; Elban, Mark A.; Courter, Joel R.; Sugawara, Akihiro; Soeta, Takahiro; Madani, Navid; Princiotto, Amy M.; Do Kwon, Young; Kwong, Peter D.; Schoen, Arne; Freire, Ernesto; Sodroski, Joseph; Smith, Amos B., III

The Active Core in a Triazole Peptide Dual-Site Antagonist of HIV-1 gp120

CHEMMEDCHEM

IF3.4

2010-10-28

OAAI

Umashankara, Muddegowda; McFadden, Karyn; Zentner, Isaac; Schoen, Arne; Rajagopal, Srivats; Tuzer, Ferit; Kuriakose, Syna A.; Contarino, Mark; LaLonde, Judith; Freire, Ernesto; Chaiken, Irwin

Indoleamine 2,3-Dioxygenase Is the Anticancer Target for a Novel Series of Potent Naphthoquinone-Based Inhibitors (vol 51, pg 1712, 2008)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-10-28

OAAI

Kumar, Sanjeev; Malachowski, William P.; DuHadaway, James B.; LaLonde, Juidth M.; Carroll, Patrick J.; Jaller, Daniel; Metz, Richard; Prendergast, George C.; Muller, Alexander J.

Structure based development of phenylimidazole-derived inhibitors of indoleamine 2,3-dioxygenase 吲哚胺2，3-双加氧酶的苯基咪唑衍生抑制剂的基于结构的开发

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-07-30

159

OAAI

Kumar, Sanjeev; Jaller, Daniel; Patel, Bhumika; LaLonde, Judith M.; DuHadaway, James B.; Malachowski, William P.; Prendergast, George C.; Muller, Alexander J.

Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-04-11

OAAI

Gopi, Hosahudya; Umashankara, M.; Pirrone, Vanessa; LaLonde, Judith; Madani, Navid; Tuzer, Ferit; Baxter, Sabine; Zentner, Isaac; Cocklin, Simon; Jawanda, Navneet; Miller, Shendra R.; Schon, Arne; Klein, Jeffrey C.; Freire, Ernesto; Krebs, Fred C.; Smith, Amos B.; Sodroski, Joseph; Chaiken, Irwin

Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-03-05

176

OAAI

Kumar, Sanjeev; Malachowski, William P.; DuHadaway, James B.; LaLonde, Judith M.; Carroll, Patrick J.; Jaller, Daniel; Metz, Richard; Prendergast, George C.; Muller, Alexander J.

Validation studies of the site-directed docking program LibDock

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2007-11-07

308

OAAI

Rao, Shashidhar N.; Head, Martha S.; Kulkarni, Amit; LaLonde, Judith M.

A critical assessment of docking programs and scoring functions

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2005-08-13

1.5K

PREAI

Warren, Gregory L.; Andrews, C. Webster; Capelli, Anna-Maria; Clarke, Brian; LaLonde, Judith; Lambert, Millard H.; Lindvall, Mika; Nevins, Neysa; Semus, Simon F.; Senger, Stefan; Tedesco, Giovanna; Wall, Ian D.; Woolven, James M.; Peishoff, Catherine E.; Head, Martha S.

Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155

JOURNAL OF VIROLOGY

IF3.8

2004-04-01

138

OAAI

Madani, N; Perdigoto, AL; Srinivasan, K; Cox, JM; Chruma, JJ; LaLonde, J; Head, M; Smith, AB; Sodroski, JG

Use of papain as a model for the structure-based design of cathepsin K inhibitors:: Crystal structures of two papain-inhibitor complexes demonstrate binding to S′-subsites

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

1998-10-21

PREAI

LaLonde, JM; Zhao, BG; Smith, WW; Janson, CA; DesJarlais, RL; Tomaszek, TA; Carr, TJ; Thompson, SK; Oh, HJ; Yamashita, DS; Veber, DF; Abdel-Meguid, SS

研究方向