Thomas G. Tampone - Publications, H-index & Citations

Thomas G. Tampone

Boehringer Ingelheim

8H指数

29论文数

261被引数

收录论文 11

发表时间

Leveraging an intelligent slug flow platform for self-optimization of reaction systems with categorical variables 利用智能 slug 流平台对含分类变量的反应系统进行自优化

Chem. Sci.

IF7.4

2025-10-13

OAAI

Florian Wagner; Gernot Neun; Thomas Tampone; Zhen Lei; Frederic Buono; Christopher A. Hone; C. Oliver Kappe

Enabling the First Scale-Up of the Selective HER2 Inhibitor BI-4142 实现选择性HER2抑制剂BI-4142的首个规模化生产

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2025-05-14

PREAI

Chong, Eugene; Li, Ruoshi; Dong, Weitong; Chevliakov, Maxim; Tampone, Thomas G.; Zhang, Yongda; Qu, Bo; Haddad, Nizar; Lorenz, Jon C.; Sarvestani, Max; Omar, Thuraya; Li, Huayu; Gao, Joe J.; Gao, Donghong A.; Pennino, Scott; Wu, Ling; Spinelli, Earl; Yao, Steven; Lee, Heewon; Buono, Frederic; Song, Jinhua J.; Wilding, Birgit

Development of a Scalable Asymmetric Process for the Synthesis of Selective PDE4B Inhibitor Nerandomilast (BI 1015550)

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2024-09-05

PREAI

Frutos, Rogelio P.; Tampone, Thomas G.; Gerstmann, Frank; Weber, Dirk; Brodmann, Tobias; Hagenko''tter, Robert; Abella, Jocelyn; Yang, Bing-Shiou; Mulder, Jason; Rodriguez, Sonia; Lee, Heewon; Gao, Joe; Song, Jinhua J.

Self-Optimizing Flow Reactions for Sustainability: An Experimental Bayesian Optimization Study

ACS SUSTAINABLE CHEMISTRY & ENGINEERING

IF7.3

2024-06-19

OAAI

Wagner, Florian L.; Sagmeister, Peter; Tampone, Thomas G.; Manee, Vidhyadhar; Yerkozhanov, Dauzhan; Buono, Frederic G.; Williams, Jason D.; Kappe, C. Oliver

A Slug Flow Platform with Multiple Process Analytics Facilitates Flexible Reaction Optimization

ADVANCED SCIENCE

IF14.1

2024-01-25

OAAI

Wagner, Florian; Sagmeister, Peter; Jusner, Clemens E.; Tampone, Thomas G.; Manee, Vidhyadhar; Buono, Frederic G.; Williams, Jason D.; Kappe, C. Oliver

Development of a Scalable Synthesis toward a KRAS G12C Inhibitor Building Block Bearing an All-Carbon Quaternary Stereocenter, Part 2: Asymmetric Synthesis via Shi Epoxidation

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2024-01-05

PREAI

Tan, Zhulin; Ju, Xuan; Wu, Hao; Dong, Weitong; Leung, Joyce C.; Hou, Xiaowen; Lee, Heewon; Granger, Alice; Paolillo, Joshua M.; Dimeo, Susan V.; Chen, Chengsheng; Wu, Linglin; Lorenz, Jon C.; Sarvestani, Max; Buono, Frederic; Frutos, Rogelio; Tampone, Thomas G.; Huang, Xiaojun; Zhang, Gulin; Wang, Yuwen; Spinelli, Earl; Lei, Zhen; Song, Jinhua J.

Development of a Scalable Asymmetric Process for the Synthesis of GLYT1 Inhibitor BI 425809 (Iclepertin)

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2023-03-03

PREAI

Frutos, Rogelio; Tampone, Thomas G.; Mulder, Jason; Gao, Joe; Sieber, Joshua D.; Rodriguez, Sonia; Haddad, Nizar; Baer, Katrin; Brown, Jack; Yang, Bing-Shiou; Giovannini, Riccardo; Song, Jinhua J.; Grinberg, Nelu; Lee, Heewon; Senanayake, Chris H.

Autonomous Multi-Step and Multi-Objective Optimization Facilitated by Real-Time Process Analytics

ADVANCED SCIENCE

IF14.1

2022-02-01

OAAI

Sagmeister, Peter; Ort, Florian F.; Jusner, Clemens E.; Hebrault, Dominique; Tampone, Thomas; Buono, Frederic G.; Williams, Jason D.; Kappe, C. Oliver

Development of a Practical Process for the Synthesis of PDE4 Inhibitors

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2016-05-05

PREAI

Frutos, Rogelio P.; Tampone, Thomas G.; Mulder, Jason A.; Rodriguez, Sonia; Yee, Nathan K.; Yang, Bing-Shiou; Senanayake, Chris H.

One-Pot Synthesis of 2,5-Disubstituted Pyrimidines from Nitriles

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2013-05-22

PREAI

Frutos, Rogelio P.; Wei, Xudong; Patel, Nitinchandra D.; Tampone, Thomas G.; Mulder, Jason A.; Busacca, Carl A.; Senanayake, Chris H.

Development of a Safe and Economical Synthesis of Methyl 6-Chloro-5-(trifluoromethyl)nicotinate: Trifluoromethylation on Kilogram Scale

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2013-05-09

PREAI

Mulder, Jason A.; Frutos, Rogelio P.; Patel, Nitinchandra D.; Qu, Bo; Sun, Xiufeng; Tampone, Thomas G.; Gao, Joe; Sarvestani, Max; Eriksson, Magnus C.; Haddad, Nizar; Shen, Sherry; Song, Jinhua J.; Senanayake, Chris H.

研究方向