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Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure-Activity Relationship Models Herman, Dorota; Kandula, Maciej M. M.; Freitas, Lorena G. A.; van Dongen, Caressa; Van, Thanh Le; Mesens, Natalie; Jaensch, Steffen; Gustin, Emmanuel; Micholt, Liesbeth; Lardeau, Charles-Hugues; Varsakelis, Christos; Reumers, Joke; Zoffmann, Sannah; Will, Yvonne; Peeters, Pieter J. J.; Ceulemans, Hugo 分享 收藏
AI/ML Models to Predict the Severity of Drug-Induced Liver Injury for Small Molecules Rao, Mohan; Nassiri, Vahid; Alhambra, Cristobal; Snoeys, Jan; Van Goethem, Freddy; Irrechukwu, Onyi; Aleo, Michael D.; Geys, Helena; Mitra, Kaushik; Will, Yvonne 分享 收藏
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Moving beyond Binary Predictions of Human Drug-Induced Liver Injury (DILI) toward Contrasting Relative Risk Potential Aleo, Michael D.; Shah, Falgun; Allen, Scott; Barton, Hugh A.; Costales, Chester; Lazzaro, Sarah; Leung, Louis; Nilson, Andrea; Obach, R. Scott; Rodrigues, A. David; Will, Yvonne 分享 收藏
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An Industry Perspective on the 2017 EMA Guideline on First-in-Human and Early Clinical Trials DeGeorge, Joseph; Robertson, Sarah; Butler, Lynne; Derzi, Mazin; Stoch, S. Aubrey; Diaz, Dolores; Hartke, James; Guzzie-Peck, Peggy; Mortimer-Cassen, Elisabeth; Bogdanffy, Matthew; Will, Yvonne; Greene, Nigel 分享 收藏
Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases Connolly, Niamh M. C.; Theurey, Pierre; Adam-Vizi, Vera; Bazan, Nicolas G.; Bernardi, Paolo; Bolanos, Juan P.; Culmsee, Carsten; Dawson, Valina L.; Deshmukh, Mohanish; Duchen, Michael R.; Dussmann, Heiko; Fiskum, Gary; Galindo, Maria F.; Hardingham, Giles E.; Hardwick, J. Marie; Jekabsons, Mika B.; Jonas, Elizabeth A.; Jordan, Joaquin; Lipton, Stuart A.; Manfredi, Giovanni; Mattson, Mark P.; McLaughlin, BethAnn; Methner, Axel; Murphy, Anne N.; Murphy, Michael P.; Nicholls, David G.; Polster, Brian M.; Pozzan, Tullio; Rizzuto, Rosario; Satrustegui, Jorgina; Slack, Ruth S.; Swanson, Raymond A.; Swerdlow, Russell H.; Will, Yvonne; Ying, Zheng; Joselin, Alvin; Gioran, Anna; Pinho, Catarina Moreira; Watters, Orla; Salvucci, Manuela; Llorente-Folch, Irene; Park, David S.; Bano, Daniele; Ankarcrona, Maria; Pizzo, Paola; Prehn, Jochen H. M. 分享 收藏
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Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic Mendrick, Donna L.; Diehl, Anna Mae; Topor, Lisa S.; Dietert, Rodney R.; Will, Yvonne; La Merrill, Michele A.; Bouret, Sebastien; Varma, Vijayalaskshmi; Hastings, Kenneth L.; Schug, Thaddeus T.; Hart, Susan G. Emeigh; Burlesona, Florence G. 分享 收藏
Current nonclinical testing paradigms in support of safe clinical trials: An IQ Consortium DruSafe perspective Butler, Lynne D.; Guzzie-Peck, Peggy; Hartke, James; Bogdanffy, Matthew S.; Will, Yvonne; Diaz, Dolores; Mortimer-Cassen, Elisabeth; Derzi, Mazin; Greene, Nigel; DeGeorge, Joseph J. 分享 收藏
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